메뉴 건너뛰기




Volumn 42, Issue 7, 1998, Pages 1695-1701

Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMPHOTERICIN B; FLUCONAZOLE; ITRACONAZOLE;

EID: 0031807604     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.7.1695     Document Type: Article
Times cited : (137)

References (42)
  • 1
    • 0029853191 scopus 로고    scopus 로고
    • Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance
    • Albertson, G. D., M. Niimi, R. D. Cannon, and H. F. Jenkinson. 1996. Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance. Antimicrob. Agents Chemother. 40:2835-2841.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2835-2841
    • Albertson, G.D.1    Niimi, M.2    Cannon, R.D.3    Jenkinson, H.F.4
  • 2
    • 0029778911 scopus 로고    scopus 로고
    • Techniques for investigation of an apparent outbreak of infections with Candida glabrata
    • Arif, S., T. Barkham, E. G. Power, and S. A. Howell. 1996. Techniques for investigation of an apparent outbreak of infections with Candida glabrata. J. Clin. Microbiol. 34:2205-2209.
    • (1996) J. Clin. Microbiol. , vol.34 , pp. 2205-2209
    • Arif, S.1    Barkham, T.2    Power, E.G.3    Howell, S.A.4
  • 3
    • 0030716391 scopus 로고    scopus 로고
    • The Candida albicans CDR3 gene codes for an opaque phase ABC transporter
    • Balan, I., A.-M. Alarco, and M. Raymond. 1997. The Candida albicans CDR3 gene codes for an opaque phase ABC transporter. J. Bacteriol. 179:7210-7218.
    • (1997) J. Bacteriol. , vol.179 , pp. 7210-7218
    • Balan, I.1    Alarco, A.-M.2    Raymond, M.3
  • 4
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi, E., M. Wang, S. Leterme, L. Van Dyck, and A. Goffeau. 1994. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J. Biol. Chem. 269:2206-2214.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 5
    • 0030671457 scopus 로고    scopus 로고
    • Molecular and phenotypic characterization of yeast PDRI mutants that show hyperactive transcription of various ABC multidrug transporter genes
    • Carvajal, E., H. B. van den Hazel, A. Cybularz-Kolaczkowska, E. Balzi, and A. Goffeau. 1997. Molecular and phenotypic characterization of yeast PDRI mutants that show hyperactive transcription of various ABC multidrug transporter genes. Mol. Gen. Genet. 256:406-415.
    • (1997) Mol. Gen. Genet. , vol.256 , pp. 406-415
    • Carvajal, E.1    Van Den Hazel, H.B.2    Cybularz-Kolaczkowska, A.3    Balzi, E.4    Goffeau, A.5
  • 6
    • 0029073576 scopus 로고
    • Identification and characterization of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane
    • Decottignies, A., L. Lambert, P. Catty, H. Degand, E. A. Epping, W. S. Moye-Rowley, E. Balzi, and A. Goffeau. 1995. Identification and characterization of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane. J. Biol. Chem. 270:18150-18157.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18150-18157
    • Decottignies, A.1    Lambert, L.2    Catty, P.3    Degand, H.4    Epping, E.A.5    Moye-Rowley, W.S.6    Balzi, E.7    Goffeau, A.8
  • 8
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Dereveux, J., P. Haeberli, and O. Smithies. 1984. a comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Dereveux, J.1    Haeberli, P.2    Smithies, O.3
  • 9
    • 0028883458 scopus 로고
    • Deletion of the Candida glabrata ERG3 and ERG11 genes: Effect on cell viability, cell growth, sterol composition, and antifungal susceptibility
    • Geber, A., C. A. Hitchcock, J. E. Swartz, F. S. Pullen, K. E. Marsden, L. J. Kwon-Chung, and J. E. Bennett. 1995. Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility. Antimicrob. Agents Chemother. 39:2708-2717.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2708-2717
    • Geber, A.1    Hitchcock, C.A.2    Swartz, J.E.3    Pullen, F.S.4    Marsden, K.E.5    Kwon-Chung, L.J.6    Bennett, J.E.7
  • 10
    • 0020530850 scopus 로고
    • Transcription terminates in yeast distal to a control sequence
    • Henikoff, S., J. D. Kelly, and E. H. Cohen. 1983. Transcription terminates in yeast distal to a control sequence. Cell 33:607-614.
    • (1983) Cell , vol.33 , pp. 607-614
    • Henikoff, S.1    Kelly, J.D.2    Cohen, E.H.3
  • 11
    • 84907123977 scopus 로고
    • The lipid composition and permeability to azole of an azole- and polyene-resistant mutant of Candida albicans
    • Hitchcock, C. A., K. J. Barrett-Bee, and N. J. Russell. 1987. The lipid composition and permeability to azole of an azole- and polyene-resistant mutant of Candida albicans. J. Med. Vet. Mycol. 25:29-37.
    • (1987) J. Med. Vet. Mycol. , vol.25 , pp. 29-37
    • Hitchcock, C.A.1    Barrett-Bee, K.J.2    Russell, N.J.3
  • 13
    • 0028807725 scopus 로고
    • Altered P450 activity associated with direct selection for fungal azole resistance
    • Joseph-Horne, T., D. W. Hollomon, R. S. Loeffler, and S. L. Kelly. 1995. Altered P450 activity associated with direct selection for fungal azole resistance. FEBS Lett. 374:174-178.
    • (1995) FEBS Lett. , vol.374 , pp. 174-178
    • Joseph-Horne, T.1    Hollomon, D.W.2    Loeffler, R.S.3    Kelly, S.L.4
  • 14
    • 0029836129 scopus 로고    scopus 로고
    • Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5
    • Katzmann, D. J., T. C. Hallstrom, Y. Mahe, and W. S. Moye-Rowley. 1996. Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5. J. Biol. Chem. 271:23049-23054.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23049-23054
    • Katzmann, D.J.1    Hallstrom, T.C.2    Mahe, Y.3    Moye-Rowley, W.S.4
  • 16
    • 0031054924 scopus 로고    scopus 로고
    • The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity
    • Lamb, D. C., D. E. Kelly, W. H. Schunck, A. Z. Shyadehi, M. Akhtar, D. J. Lowe, B. C. Baldwin, and S. L. Kelly. 1997. The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity. J. Biol. Chem. 272:5682-5688.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5682-5688
    • Lamb, D.C.1    Kelly, D.E.2    Schunck, W.H.3    Shyadehi, A.Z.4    Akhtar, M.5    Lowe, D.J.6    Baldwin, B.C.7    Kelly, S.L.8
  • 17
    • 0026439153 scopus 로고
    • Genotypic identification and characterization of species and strains within the genus Candida by using random amplified polymorphic DNA
    • Lehmann, P. F., D. Lin, and B. A. Lasker. 1992. Genotypic identification and characterization of species and strains within the genus Candida by using random amplified polymorphic DNA. J. Clin. Microbiol. 30:3249-3254.
    • (1992) J. Clin. Microbiol. , vol.30 , pp. 3249-3254
    • Lehmann, P.F.1    Lin, D.2    Lasker, B.A.3
  • 19
    • 0027262399 scopus 로고
    • The nucleotide sequence of the 25S rRNA-encoding gene from Candida albicans
    • Mercure, S., N. Rougeau, S. Montplaisir, and G. Lemay. 1993. The nucleotide sequence of the 25S rRNA-encoding gene from Candida albicans. Nucleic Acids Res. 21:1490.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1490
    • Mercure, S.1    Rougeau, N.2    Montplaisir, S.3    Lemay, G.4
  • 20
    • 0029202916 scopus 로고
    • Functional analysis of the promoter of the Saccharomyces cerevisiae multidrug resistance gene YDR1, which encodes a member of the ATP Binding Cassette (ABC) superfamily
    • Miyahara, K., D. Hirata, and T. Miyakawa. 1995. Functional analysis of the promoter of the Saccharomyces cerevisiae multidrug resistance gene YDR1, which encodes a member of the ATP Binding Cassette (ABC) superfamily. Biosci. Biotechnol. Biochem. 59:147-149.
    • (1995) Biosci. Biotechnol. Biochem. , vol.59 , pp. 147-149
    • Miyahara, K.1    Hirata, D.2    Miyakawa, T.3
  • 21
    • 0028957971 scopus 로고
    • +, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily
    • +, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily. J. Bacteriol. 177:1536-1543.
    • (1995) J. Bacteriol. , vol.177 , pp. 1536-1543
    • Nagao, K.1    Taguchi, Y.2    Arioka, M.3    Kadokura, H.4    Takatsuki, A.5    Yoda, J.6    Yamasaki, M.7
  • 22
    • 0028287541 scopus 로고
    • CHROMagar Candida, a new differential isolation medium for presumptive identification of clinically important Candida species
    • Odds, F. C., and R. Bernaerts. 1994. CHROMagar Candida, a new differential isolation medium for presumptive identification of clinically important Candida species. J. Clin. Microbiol. 32:1923-1929.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 1923-1929
    • Odds, F.C.1    Bernaerts, R.2
  • 23
    • 0029130683 scopus 로고
    • Fluconazole resistance due to energy-dependent drug efflux in Candida glabrata
    • Parkinson, T., D. J. Falconer, and C. A. Hitchcock. 1995. Fluconazole resistance due to energy-dependent drug efflux in Candida glabrata. Antimicrob. Agents Chemother. 39:1696-1699.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1696-1699
    • Parkinson, T.1    Falconer, D.J.2    Hitchcock, C.A.3
  • 24
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals
    • Prasad, R., P. D. Wergifosse, A. Goffeau, and E. Balzi. 1995. Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr. Genet. 27:320-329.
    • (1995) Curr. Genet. , vol.27 , pp. 320-329
    • Prasad, R.1    Wergifosse, P.D.2    Goffeau, A.3    Balzi, E.4
  • 27
    • 0027993041 scopus 로고
    • Epidemiology of oral candidiasis in HIV-infected patients: Colonization, infection, treatment and emergence of fluconazole resistance
    • Sangeorzan, J. A., S. F. Bradley, H. Xiaogang, L. T. Zarins, G. L. Ridenour, R. N. Tiballi, and C. A. Kauffman. 1994. Epidemiology of oral candidiasis in HIV-infected patients: colonization, infection, treatment and emergence of fluconazole resistance. Am. J. Med. 97:339-346.
    • (1994) Am. J. Med. , vol.97 , pp. 339-346
    • Sangeorzan, J.A.1    Bradley, S.F.2    Xiaogang, H.3    Zarins, L.T.4    Ridenour, G.L.5    Tiballi, R.N.6    Kauffman, C.A.7
  • 28
    • 0028793725 scopus 로고
    • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    • Sanglard, D., K. Kuchler, F. Ischer, J.-L. Pagani, M. Monod, and J. Bille. 1995. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob. Agents Chemother. 39:2378-2386.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2378-2386
    • Sanglard, D.1    Kuchler, K.2    Ischer, F.3    Pagani, J.-L.4    Monod, M.5    Bille, J.6
  • 29
    • 0029820482 scopus 로고    scopus 로고
    • Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    • Sanglard, D., F. Ischer, M. Monod, and J. Bille. 1996. Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrob. Agents Chemother. 40:2300-2305.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 2300-2305
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 30
    • 0031938057 scopus 로고    scopus 로고
    • Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents
    • Sanglard, D., F. Ischer, L. Koymans, and J. Bille. 1998. Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob. Agents Chemother. 42:241-253.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 241-253
    • Sanglard, D.1    Ischer, F.2    Koymans, L.3    Bille, J.4
  • 31
    • 0031047670 scopus 로고    scopus 로고
    • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: Characterization of CDR2, a new multidrug ABC transporter gene
    • Sanglard, D., F. Ischer, M. Monod, and J. Bille. 1997. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene. Microbiology 143: 405-416.
    • (1997) Microbiology , vol.143 , pp. 405-416
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 33
    • 0029834495 scopus 로고    scopus 로고
    • The unusual inheritance of multidrug-resistance factors in Saccharomyces
    • Shallom, J. M., and J. Golin. 1996. The unusual inheritance of multidrug-resistance factors in Saccharomyces. Curr. Genet. 30:212-217.
    • (1996) Curr. Genet. , vol.30 , pp. 212-217
    • Shallom, J.M.1    Golin, J.2
  • 34
    • 0029100965 scopus 로고
    • Candida dublinensis sp. nov.: Phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals
    • Sullivan, D. J., T. J. Westerneng, K. A. Haynes, D. E. Bennett, and D. C. Coleman. 1995. Candida dublinensis sp. nov.: phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals. Microbiology 141:1507-1521.
    • (1995) Microbiology , vol.141 , pp. 1507-1521
    • Sullivan, D.J.1    Westerneng, T.J.2    Haynes, K.A.3    Bennett, D.E.4    Coleman, D.C.5
  • 35
    • 0029822361 scopus 로고    scopus 로고
    • Analysis of the risk factors associated with the emergence of azole resistant oral candidosis in the course of HIV infection
    • Tumbarello, M., G. Caldarola, E. Tacconelli, G. Morace, B. Posteraro, R. Cauda, and L. Ortona. 1996. Analysis of the risk factors associated with the emergence of azole resistant oral candidosis in the course of HIV infection. J. Antimicrob. Chemother. 38:691-699.
    • (1996) J. Antimicrob. Chemother. , vol.38 , pp. 691-699
    • Tumbarello, M.1    Caldarola, G.2    Tacconelli, E.3    Morace, G.4    Posteraro, B.5    Cauda, R.6    Ortona, L.7
  • 38
    • 0001607723 scopus 로고
    • Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker, J. E., M. Saraste, M. J. Runswick, and N. J. Gay. 1982. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:945-951.
    • (1982) EMBO J. , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 40
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
    • White, T. C. 1997. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob. Agents Chemother. 41:1482-1487.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1482-1487
    • White, T.C.1
  • 41
    • 0030792602 scopus 로고    scopus 로고
    • The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α demethylase in Candida albicans
    • White, T. C. 1997. The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14α demethylase in Candida albicans. Antimicrob. Agents Chemother. 41:1488-1494.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 1488-1494
    • White, T.C.1
  • 42
    • 0020108296 scopus 로고
    • DNA sequence required for efficient transcription termination in yeast
    • Zaret, K. S., and F. Sherman. 1982. DNA sequence required for efficient transcription termination in yeast. Cell 28:563-573.
    • (1982) Cell , vol.28 , pp. 563-573
    • Zaret, K.S.1    Sherman, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.