Inhibition of oxidative cross-linking between engineered cysteine residues at positions 332 in predicted transmembrane segments (TM) 6 and 975 in predicted TM12 of human P-glycoprotein by drug substrates

Journal of Biological Chemistry

Volumn 271, Issue 44, 1996, Pages 27482-27487

  Loo, Tip W ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; BINDING PROTEIN; COLCHICINE; CYSTEINE; GLYCOPROTEIN P; MEMBRANE PROTEIN; MUTANT PROTEIN; OXIDIZING AGENT; VERAPAMIL; VINBLASTINE;

ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; EMBRYO; ENZYME SUBSTRATE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; OXIDATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BINDING SITES; CELL MEMBRANE; COLCHICINE; CROSS-LINKING REAGENTS; CYSTEINE; DNA, COMPLEMENTARY; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDANTS; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; POINT MUTATION; RECOMBINANT PROTEINS; TRANSFECTION; VERAPAMIL; VINBLASTINE;

EID: 0029909604     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.44.27482     Document Type: Article

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