CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain of Candida albicans

Yeast

Volumn 18, Issue 12, 2001, Pages 1117-1129

  Panwar, Sneh Lata ^a   Krishnamurthy, Shankarling ^a   Gupta, Vinita ^a   Alarco, Anne Marie ^b   Raymond, Martine ^c   Sanglard, Dominique ^a   Prasad, Rajendra ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Alkane inducible cytochrome P450; Candida albicans; Multidrug resistance

Indexed keywords

1,10 PHENANTHROLINE; 4 NITROQUINOLINE 1 OXIDE; ABC TRANSPORTER; ALKANE; CYCLOHEXIMIDE; CYTOCHROME P450; DRUG; FATTY ACID; FLUCONAZOLE; NUCLEOTIDE; PYRROLE DERIVATIVE;

ARTICLE; CANDIDA ALBICANS; CANDIDA TROPICALIS; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; DRUG SENSITIVITY; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE ISOLATION; GENE SEQUENCE; GENETIC CODE; HOMOZYGOSITY; HYDROXYLATION; MULTIDRUG RESISTANCE; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

4-NITROQUINOLINE-1-OXIDE; AMINO ACID SEQUENCE; ANTIFUNGAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; CANDIDA ALBICANS; CYCLOHEXIMIDE; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, MULTIPLE, FUNGAL; FLUCONAZOLE; GENE EXPRESSION REGULATION, FUNGAL; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PHENANTHROLINES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034834285     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.762     Document Type: Article

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