Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei

Medical Mycology

Volumn 39, Issue 1, 2001, Pages 109-116

  Katiyar, S K ^a   Edlind, T D ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

ABC transporter; Azoles; MDR; Multidrug resistance

Indexed keywords

ABC TRANSPORTER; ALBENDAZOLE; CLOTRIMAZOLE; CYCLOHEXIMIDE; FLUCONAZOLE; MICONAZOLE; PYRROLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA KRUSEI; DRUG ANTAGONISM; FUNGAL GENETICS; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENOME; IN VITRO STUDY; MULTIDRUG RESISTANCE; NONHUMAN; SOUTHERN BLOTTING;

CANDIDA; CANDIDA ALBICANS; CANDIDA KRUSEI; FUNGI; ISSATCHENKIA ORIENTALIS;

EID: 0035120054     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/mmy.39.1.109.116     Document Type: Article

References (26)

1. Antifungal drug resistance in pathogenic fungi
2. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
3. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with Human Immunodeficiency Virus
4. Origin of differences in susceptibility of Candida krusei to azole antifungal agents
5. Resistance of Candida species to fluconazole
6. Importance of Candida species other than C. albicans as pathogens in oncology patients
7. Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance
8. Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs
9. Mechanism of fluconazole resistance in Candida krusei
10. Genetics and biochemistry of yeast multidrug resistance
11. Complete inventory of the yeast ABC proteins
12. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: Characterization of CDR2, a new multidrug ABC transporter gene
13. Multidrug resistance in Aspergillus nidulans involves novel ATP-binding cassette transporters
14. Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata
15. The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents
16. Identification of Candida krusei multidrug resistance genes: Potential role in azole resistance
17. A rapid and simple method for preparation of RNA from Saccharomyces cerevesiae
18. Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents
19. Rapid fungicidal action of tioconazole and miconazole
20. Distantly related sequences in the α and β subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
21. Expression of CDR1, a multidrug resistance gene of Candida albicans: Transcriptional activation by heat shock, drugs and human steroid hormones
22. Saccharomyces cerevisiae YDR1, which encodes a member of the ATP-binding cassette (ABC) superfamily, is required for multidrug resistance
23. Genetics of MDR-mediated azole resistance in Saccharomyces cerevisiae
24. A general pattern for substrate recognition by P-glycoprotein
25. Interpretation of trailing endpoints in antifungal susceptibility testing by the National Committee for Clinical Laboratory Standards method