The glyoxylate cycle is required for fungal virulence

Nature

Volumn 412, Issue 6842, 2001, Pages 83-86

  Lorenz, M C ^a   Fink, G R ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CELLS; ENZYMES; FUNGI; GENES; PATIENT MONITORING;

FUNGAL VIRULENCE;

FUNGUS ATTACK;

GLYOXYLIC ACID;

FUNGUS;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; FUNGAL VIRULENCE; FUNGUS MUTANT; GENOME; LYSOSOME; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; VIRULENCE;

ANIMALS; CANDIDA ALBICANS; CANDIDIASIS; CELL LINE; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; GLYOXYLATES; ISOCITRATE LYASE; MACROPHAGES; MALATE SYNTHASE; MICE; MICE, INBRED C57BL; MUTAGENESIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHAGOCYTOSIS; SACCHAROMYCES CEREVISIAE; TRICARBOXYLIC ACIDS; UP-REGULATION; VIRULENCE;

ANIMALIA; CANDIDA ALBICANS; FUNGI; MAMMALIA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; SACCHAROMYCES CEREVISIAE;

EID: 0035811478     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35083594     Document Type: Article

References (18)

1. Production and function of cytokines in natural and acquired immunity to Candida albicans infection
2. Nonfilamentous C. albicans mutants are avirulent
3. Nosocomial Candida. Epidemiology, transmission, and prevention
4. Fungal infections in cancer patients: An international autopsy survey
5. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
6. Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis
7. Characterization of mutants of the yeast Yarrowia lipolytica defective in acetyl-coenzyme A synthetase
8. Trans-dominant mutations in the GPR1 gene cause high sensitivity to acetic acid and ethanol in the yeast Yarrowia lipolytica
9. Fructose bisphosphatase of Saccharomyces cerevisiae, Cloning, disruption and regulation of the FBP1 structural gene
10. Isolation, nucleotide sequence analysis, and disruption of the MDH2 gene from Saccharomyces cerevisiae: Evidence for three isozymes of yeast malate dehydrogenase
11. Genealogy of principal strains of the yeast genetic stock center
12. Genome-wide expression monitoring in Saccharomyces cerevisiae
13. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
14. Isogenic strain construction and gene mapping in Candida albicans
15. Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura 3 and E. coli pyrF mutations
16. Cloning and expression of Candida albicans ADE2 and proteinase genes on a replicative plasmid in C. albicans and in Saccharomyces cerevisiae
17. Control of filament formation in Candida albicans by the transcriptional repressor TUP1
18. Getting started with yeast