Amino acid substitutions in the cytochrome P-450 lanosterol 14α- demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 2, 1998, Pages 241-253

  Sanglard, Dominique ^a   Ischer, Françoise ^a   Koymans, Luc ^b   Bille, Jacques ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CYP 51 A 1; CYTOCHROME P450 ISOENZYME; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CANDIDA ALBICANS; DRUG PROTEIN BINDING; DRUG RESISTANCE; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANTIFUNGAL AGENTS; AZOLES; CANDIDA ALBICANS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG RESISTANCE, MICROBIAL; FLUCONAZOLE; FUNGAL PROTEINS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDOREDUCTASES; PROTEIN STRUCTURE, SECONDARY;

EID: 0031938057     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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