In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network

Microbial Drug Resistance

Volumn 4, Issue 3, 1998, Pages 143-158

  Kolaczkowski, Marcin ^a   Kolaczkowska, Anna ^a   Luczynski, Jacek ^b   Witek, Stanislaw ^b   Goffeau, Andre ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANILINE DERIVATIVE; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; BENZIMIDAZOLE DERIVATIVE; BETA GALACTOSIDASE; BILE ACID; CYANIDE; DETERGENT; DISINFECTANT AGENT; DITHIOCARBAMIC ACID DERIVATIVE; ESTER; FLAVONOID; FUNGICIDE; GUANIDINE DERIVATIVE; HERBICIDE; IONOPHORE; MEMBRANE LIPID; METHANOL DERIVATIVE; POLYENE; PYRIMIDINE DERIVATIVE; RHODAMINE; THIAZOLE DERIVATIVE; UREA DERIVATIVE;

ARTICLE; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE; GENE DISRUPTION; MULTIDRUG RESISTANCE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

EID: 0031796062     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.1998.4.143     Document Type: Article

References (13)

1. Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116:541-545.
2. Alarco, A.M., I. Balan, D. Talibi, N. Mainville, and M. Raymond. 1997. AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 a tansporter of the Major Facilitator superfamily. J. Biol. Chem. 272:19304-19313.
3. Albertson, G.D., M. Niimi, R.D. Cannon, and H.F. Jenkinson. 1996. Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance. Antimicrob. Agents Chemother. 40:2835-2841.
4. Balzi, E., and A. Goffeau. 1995. Yeast multidrug resistance: The PDR network. J. Bioenerg. Biomembr. 27:71-76.
5. Balzi, E., W. Chen, S. Ulaszewski, E. Capieaux, and A. Goffeau. 1987. The multidrug resistance gene PDR1 from Saccharomyces cerevisiae. J. Biol. Chem. 262:16871-16879.
6. Bien, M., T.M. Lachowicz, E. Sauter, J. Luczynski, and S. Witek. 1995. Antifungal activity of some model "soft" lysosomotropic compounds. Bull. Polish Acad. Sci. 43:108-112.
7. Bissonnette, L., S. Champetier, J.P. Buisson, and P.H. Roy. 1991. Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of TN1696: Similarity of the product to transmembrane transport proteins. J. Bacteriol. 173:4493-4502.
8. Boeke, J.D., F. Lacroute, and G.R. Fink. 1984. A positive selection for mutants lacking orotidine 5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197:345-346.
9. Bolhuis, H., H.W. van Veen, D. Molenaar, B. Poolman, A.J.M. Driessen, and W.N. Konings. 1996. Multidrug resistance in Lactococcus lactis: Evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. EMBO J. 15:4239-4245.
10. Bolhuis, H., H.W. van Veen, J.R. Brands, M. Putman, B. Poolman, AJ.M. Driessen, and W.N. Konings. 1996. Energetics and mechanism of drug transport mediated by the lactococcal multidrug transporter LmrP. J. Biol. Chem. 271:24123-24128.
11. Borst, P., and M. Ouelette. 1995. New mechanisms of drug resistance in parasitic protozoa. Ann. Rev. Microbiol. 49:427-460.
12. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
13. Breeden, L., and Nasmyth, K. 1985. Cold Spring symposia on quantitative biology. Vol. 50. Cold Spring Harbor Lab., Cold Spring Harbor, New York, p. 643.