Multiple Effects of Aspartate Mutant Presenilin 1 on the Processing and Trafficking of Amyloid Precursor Protein

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43343-43350

  Kim, Seong Hun ^a   Yoon Leem, Jae ^a   Lah, James J ^b   Slunt, Hilda H ^c   Levey, Allan I ^b   Thinakaran, Gopal ^a   Sisodia, Sangram S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS;

MUTATION;

PROTEINS;

ALANINE; AMYLOID PRECURSOR PROTEIN; ASPARTIC ACID; PRESENILIN 1; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; COMPLEMENTARY DNA; MEMBRANE PROTEIN; PEPTIDE; PROTEINASE; SECRETASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; MOUSE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN STABILITY; ANIMAL; BIOTINYLATION; CELL CULTURE; CELL LINE; CELL MEMBRANE; CHEMISTRY; CODON; CONFOCAL MICROSCOPY; ELECTRON MICROSCOPY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SERODIAGNOSIS; TIME; WESTERN BLOTTING;

ANIMALIA;

ALANINE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID; ASPARTIC ENDOPEPTIDASES; BIOTINYLATION; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CODON; DNA, COMPLEMENTARY; ENDOPEPTIDASES; MEMBRANE PROTEINS; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MUTATION; PEPTIDES; PRECIPITIN TESTS; PRESENILIN-1; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035900686     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108245200     Document Type: Article

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