The discrepancy between presenilin subcellular localization and γ-secretase processing of amyloid precursor protein

Journal of Cell Biology

Volumn 154, Issue 4, 2001, Pages 731-740

  Cupers, Philippe ^a   Bentahir, Mustapha ^a   Craessaerts, Katleen ^a   Orlans, Isabelle ^a   Vanderstichele, Hugo ^c   Saftig, Paul ^b   De Strooper, Bart ^a,d   Annaert, Wim ^a,d  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c INNOGENETICS   (Belgium)

^d CENTER FOR HUMAN GENETICS   (Belgium)

Author keywords

secretase; Amyloid peptide; APP processing; ER retention; Presenilin 1

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BREFELDIN A; GAMMA SECRETASE; LYSINE; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENDOSOME; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GOLGI COMPLEX; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; RAT;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELL COMPARTMENTATION; CELLS, CULTURED; ENDOPEPTIDASES; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; MEMBRANE PROTEINS; MICE; MUTATION; NEURONS; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT;

ANIMALIA;

EID: 0035921427     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200104045     Document Type: Article

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