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Volumn 187, Issue 10, 1998, Pages 1555-1564

CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells

Author keywords

Adoptive T cell transfer; Antigen presenting cells; CD4+ T cells; Peripheral tolerance; Transgenic mice

Indexed keywords

ANTIGEN; CD4 ANTIGEN; HEMAGGLUTININ; T LYMPHOCYTE RECEPTOR;

EID: 0032543225     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.10.1555     Document Type: Article
Times cited : (247)

References (43)
  • 1
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler, J., M. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell. 49:273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.1    Roehm, M.2    Marrack, P.3
  • 2
    • 0025339512 scopus 로고
    • Self-nonself discrimination by T cells
    • von Boehmer, H., and P. Kisielow. 1990. Self-nonself discrimination by T cells. Science. 248:1369-1373.
    • (1990) Science , vol.248 , pp. 1369-1373
    • Von Boehmer, H.1    Kisielow, P.2
  • 3
    • 0024402836 scopus 로고
    • Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells
    • Lo, D., L.C. Burkly, R.A. Flavell, R.D. Palmiter, and R.L. Brinster. 1989. Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells. J. Exp. Med. 170:87-104.
    • (1989) J. Exp. Med. , vol.170 , pp. 87-104
    • Lo, D.1    Burkly, L.C.2    Flavell, R.A.3    Palmiter, R.D.4    Brinster, R.L.5
  • 5
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response
    • Oldstone, M.B., M. Nerenberg, P. Southern, J. Price, and H. Lewicki. 1991. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response. Cell. 65:319-331.
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.B.1    Nerenberg, M.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 6
    • 0028199631 scopus 로고
    • Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness
    • Harlan, D.M., H. Hengartner, M.L. Huang, Y.H. Kang, R. Abe, R.W. Moreadith, H. Pircher, G.S. Gray, P.S. Ohashi, G.J. Freeman, et al. 1994. Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proc. Natl. Acad. Sci. USA. 91:3137-3141.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3137-3141
    • Harlan, D.M.1    Hengartner, H.2    Huang, M.L.3    Kang, Y.H.4    Abe, R.5    Moreadith, R.W.6    Pircher, H.7    Gray, G.S.8    Ohashi, P.S.9    Freeman, G.J.10
  • 7
    • 0029551987 scopus 로고
    • Coexpression of B7-1 and viral ("self') transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes
    • von Herrath, M.G., S. Guerder, H. Lewicki, R.A. Flavell, and M.B. Oldstone. 1995. Coexpression of B7-1 and viral ("self') transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. Immunity. 3:727-738.
    • (1995) Immunity , vol.3 , pp. 727-738
    • Von Herrath, M.G.1    Guerder, S.2    Lewicki, H.3    Flavell, R.A.4    Oldstone, M.B.5
  • 8
    • 0025693909 scopus 로고
    • Peripheral clonal elimination of functional T cells
    • Jones, L.A., L.T. Chin, D.L. Longo, and A.M. Kruisbeek. 1990. Peripheral clonal elimination of functional T cells. Science. 250:1726-1739.
    • (1990) Science , vol.250 , pp. 1726-1739
    • Jones, L.A.1    Chin, L.T.2    Longo, D.L.3    Kruisbeek, A.M.4
  • 11
    • 0025908321 scopus 로고
    • Peripheral selection of the T cell repertoire
    • Rocha, B., and H. von Boehmer. 1991. Peripheral selection of the T cell repertoire. Science. 251:1225-1228.
    • (1991) Science , vol.251 , pp. 1225-1228
    • Rocha, B.1    Von Boehmer, H.2
  • 12
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • Webb, S., C. Morris, and J. Sprent. 1990. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell. 63:1249-1256.
    • (1990) Cell , vol.63 , pp. 1249-1256
    • Webb, S.1    Morris, C.2    Sprent, J.3
  • 17
    • 0029121077 scopus 로고
    • Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance
    • Zhang, L., W. Fung-Leung, and R.G. Miller. 1995. Down-regulation of CD8 on mature antigen-reactive T cells as a mechanism of peripheral tolerance. J. Immunol. 155:3464-3471.
    • (1995) J. Immunol. , vol.155 , pp. 3464-3471
    • Zhang, L.1    Fung-Leung, W.2    Miller, R.G.3
  • 18
    • 0024327899 scopus 로고
    • Clonal expansion versus functional clonal inactivation: A costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller, D.L., M.K. Jenkins, and R.H. Schwartz. 1989. Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7: 445-480.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 19
    • 0024381358 scopus 로고
    • A nondeletional mechanism of thymic self tolerance
    • Ramsdell, F., T. Lantz, and B.J. Fowlkes. 1989. A nondeletional mechanism of thymic self tolerance. Science. 246:1038-1041.
    • (1989) Science , vol.246 , pp. 1038-1041
    • Ramsdell, F.1    Lantz, T.2    Fowlkes, B.J.3
  • 20
    • 0024398589 scopus 로고
    • T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I-E
    • Burkly, L.C., D. Lo, O. Kanagawa, R.L. Brinster, and R.A. Flavell. 1989. T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I-E. Nature. 342:564-566.
    • (1989) Nature , vol.342 , pp. 564-566
    • Burkly, L.C.1    Lo, D.2    Kanagawa, O.3    Brinster, R.L.4    Flavell, R.A.5
  • 21
    • 0025334064 scopus 로고
    • Tolerance in transgenic mice expressing major histocompatibility molecules extrathymically on pancreatic cells
    • Burkly, L.C., D. Lo, and R.A. Flavell. 1990. Tolerance in transgenic mice expressing major histocompatibility molecules extrathymically on pancreatic cells. Science. 248:1364-1368.
    • (1990) Science , vol.248 , pp. 1364-1368
    • Burkly, L.C.1    Lo, D.2    Flavell, R.A.3
  • 22
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz, R.H. 1990. A cell culture model for T lymphocyte clonal anergy. Science. 248:1349-1356.
    • (1990) Science , vol.248 , pp. 1349-1356
    • Schwartz, R.H.1
  • 23
    • 0028428910 scopus 로고
    • The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen
    • Guerder, S., J. Meyerhoff, and R. Flavell. 1994. The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen. Immunity. 1:155-166.
    • (1994) Immunity , vol.1 , pp. 155-166
    • Guerder, S.1    Meyerhoff, J.2    Flavell, R.3
  • 25
    • 0026593440 scopus 로고
    • Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens
    • Eynon, E.E., and D.C. Parker. 1992. Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens. J. Exp. Med. 175:131-138.
    • (1992) J. Exp. Med. , vol.175 , pp. 131-138
    • Eynon, E.E.1    Parker, D.C.2
  • 26
    • 0026451165 scopus 로고
    • B cells turn off virgin but not memory T cells
    • Fuchs, E.J., and P. Matzinger. 1992. B cells turn off virgin but not memory T cells. Science. 258:1156-1159.
    • (1992) Science , vol.258 , pp. 1156-1159
    • Fuchs, E.J.1    Matzinger, P.2
  • 28
    • 0021676380 scopus 로고
    • Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells
    • Townsend, A.R., A.J. McMichael, N.P. Carter, J.A. Huddleston, and G.G. Brownlee. 1984. Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells. Cell. 39:13-25.
    • (1984) Cell , vol.39 , pp. 13-25
    • Townsend, A.R.1    McMichael, A.J.2    Carter, N.P.3    Huddleston, J.A.4    Brownlee, G.G.5
  • 30
    • 0020663605 scopus 로고
    • Prostatic steroid-binding protein. Isolation and characterization of C3 genes
    • Parker, M., R. White, H. Hurst, M. Needham, and R. Tilly. 1983. Prostatic steroid-binding protein. Isolation and characterization of C3 genes. J. Biol. Chem. 258:12-15.
    • (1983) J. Biol. Chem. , vol.258 , pp. 12-15
    • Parker, M.1    White, R.2    Hurst, H.3    Needham, M.4    Tilly, R.5
  • 31
    • 0024596941 scopus 로고
    • Tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein in transgenic mice
    • Allison, J., Y. Zhang, and M. Parker. 1989. Tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein in transgenic mice. Mol. Cell. Biol. 9:2254-2257.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2254-2257
    • Allison, J.1    Zhang, Y.2    Parker, M.3
  • 32
    • 0028574256 scopus 로고
    • T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance
    • Miller, J.F., and R.A. Flavell. 1994. T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance. Curr. Opin. Immunol. 6:892-899.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 892-899
    • Miller, J.F.1    Flavell, R.A.2
  • 33
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Kearney, E.R., K.A. Pape, D.Y. Loh, and M.K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity. 1:327-339.
    • (1994) Immunity , vol.1 , pp. 327-339
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 34
    • 0029823232 scopus 로고    scopus 로고
    • Peripheral tolerance of CD4 T cells following local activation in adolescent mice
    • Forster, I., and I. Lieberam. 1996. Peripheral tolerance of CD4 T cells following local activation in adolescent mice. Eur. J. Immunol. 26:3194-3202.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 3194-3202
    • Forster, I.1    Lieberam, I.2
  • 36
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science. 272:60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 37
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
    • Finkelman, F.D., A. Lees, R. Birnbaum, W.C. Gause, and S.C. Morris. 1996. Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. J. Immunol. 157: 1406-1414.
    • (1996) J. Immunol. , vol.157 , pp. 1406-1414
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3    Gause, W.C.4    Morris, S.C.5
  • 38
    • 0027493158 scopus 로고
    • The role of macrophages in antigen presentation and T cell tolerance
    • Miyazaki, T., C. Suzuki, and K. Yamamura. 1993. The role of macrophages in antigen presentation and T cell tolerance. Int. Immunol. 5:1023-1033.
    • (1993) Int. Immunol. , vol.5 , pp. 1023-1033
    • Miyazaki, T.1    Suzuki, C.2    Yamamura, K.3
  • 39
    • 0027170482 scopus 로고
    • Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes
    • Lo, D., C.R. Reilly, B. Scott, R. Liblau, H.O. McDevitt, and L.C. Burkly. 1993. Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes. Eur. J. Immunol. 23:1693-1698.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1693-1698
    • Lo, D.1    Reilly, C.R.2    Scott, B.3    Liblau, R.4    McDevitt, H.O.5    Burkly, L.C.6
  • 41
    • 0029795112 scopus 로고    scopus 로고
    • Dendritic cells and tolerance induction
    • Steptoe, R.J., and A.W. Thomson. 1996. Dendritic cells and tolerance induction. Clin. Exp. Immunol. 105:397-402.
    • (1996) Clin. Exp. Immunol. , vol.105 , pp. 397-402
    • Steptoe, R.J.1    Thomson, A.W.2
  • 42
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang, A.Y., P. Golumbek, M. Ahmadzadeh, E. Jaffee, D. Pardoll, and H. Levitsky. 1994. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 264:961-965.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 43
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff, G., E. Jaffee, A. Lazenby, P. Golumbek, H. Levitsky, K. Brose, V. Jackson, H. Hamada, D. Pardoll, and R.C. Mulligan. 1993. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA. 90:3539-3543.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.