-
2
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
6
-
-
0033063179
-
Caspases and cytokines: Roles in inflammation and autoimmunity
-
(1998)
Adv. Immunol.
, vol.73
, pp. 265-287
-
-
Reed, J.C.1
-
10
-
-
0030782177
-
Cytochrome c: Can't live with it; can't live without it
-
(1997)
Cell
, vol.91
, pp. 559-562
-
-
Reed, J.C.1
-
12
-
-
0032143986
-
Targeted disruption of the mouse caspase8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenataly
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.1
-
13
-
-
0032505127
-
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
-
(1998)
Curr. Biol.
, vol.8
, pp. 1001-1008
-
-
Juo, P.1
-
14
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase9
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
-
15
-
-
0032493870
-
Differential requirement for caspase9 in apoptotic pathways in vivo
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
-
16
-
-
0006871386
-
The atomic-resolution structure of human caspase-8, a key activator of apoptosis
-
(1999)
Struct. Fold. Des.
, vol.7
, pp. 1135-1143
-
-
Watt, W.1
-
19
-
-
0028170376
-
Structure and mechanism of interleukin-1β converting enzyme
-
(1994)
Nature
, vol.370
, pp. 270-275
-
-
Wilson, K.P.1
-
20
-
-
15844393657
-
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 619-625
-
-
Rotonda, J.1
-
21
-
-
0030889913
-
Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-asp-val-ala-asp fluoromethyl ketone
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6539-6547
-
-
Mittl, P.1
-
22
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.1
-
23
-
-
0032491247
-
Conformationally constrained inhibitors of caspase-1 (interleukin-1 β converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain)
-
(1998)
Bioorg. Med. Chem. Letters
, vol.8
, pp. 2757-2762
-
-
Karanewsky, D.S.1
-
24
-
-
0029670265
-
ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 297-301
-
-
Nicholson, D.W.1
-
25
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
(1998)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
-
26
-
-
0032080197
-
Defects in regulation of apoptosis in caspase-2-deficient mice
-
(1998)
Genes Dev.
, vol.12
, pp. 1304-1314
-
-
Bergeron, L.1
-
27
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
-
28
-
-
0033587128
-
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
-
(1999)
Nature
, vol.399
, pp. 263-267
-
-
Ona, V.O.1
-
29
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
-
(1998)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
-
31
-
-
0032870898
-
Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo
-
(1999)
J. Mol. Cell. Cardiol.
, vol.31
, pp. 1709-1715
-
-
Holly, T.A.1
-
32
-
-
0034131832
-
Protective effect of a caspase inhibitor in models for cerebral ischemia in vitro and in vivo
-
(2000)
Cell Mol. Biol.
, vol.46
, pp. 53-62
-
-
Wiessner, C.1
-
33
-
-
0034660250
-
Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
-
(2000)
J. Neurosci.
, vol.20
, pp. 4398-4404
-
-
Rabuffetti, M.1
-
34
-
-
0032055225
-
Activation of caspase 3 (CPP32)-like proteases is essential for TNF-α-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model
-
(1998)
J. Immunol.
, vol.160
, pp. 3480-3486
-
-
Jaeschke, H.1
-
35
-
-
0032999182
-
Inhibition of caspase activity prevents CD95-mediated hepatic microvascular perfusion failure and restores Kupffer cell clearance capacity
-
(1999)
FASEB J.
, vol.13
, pp. 1239-1248
-
-
Wanner, G.A.1
-
36
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
-
39
-
-
0032575723
-
Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
-
(1998)
Science
, vol.281
, pp. 1355-1357
-
-
Yang, X.1
-
40
-
-
0033596980
-
An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
-
41
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
-
42
-
-
0034658130
-
ATP-activated oligomerization as a mechanism for apoptosis regulation: Fold and mechanism prediction for CED-4
-
(2000)
Proteins
, vol.39
, pp. 197-203
-
-
Jaroszewski, L.1
-
43
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
-
44
-
-
0033532091
-
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12955-12958
-
-
Bertin, J.1
-
45
-
-
0035937797
-
NAC: A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis
-
in press
-
J. Biol. Chem.
-
-
Chu, Z.-L.1
-
46
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4812-1818
-
-
Ogura, Y.1
-
47
-
-
0033556151
-
Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-α and Fas-induced cell death
-
(1999)
EMBO J.
, vol.18
, pp. 353-362
-
-
Kissil, J.1
-
50
-
-
0034644508
-
Insights into programmed cell death through structural biology
-
(2000)
Cell
, vol.103
, pp. 273-282
-
-
Fesik, S.W.1
-
51
-
-
0032735232
-
Surviving apoptosis: An interloper between cell death and cell proliferation in cancer
-
(1999)
Lab. Invest.
, vol.79
, pp. 1327-1333
-
-
Altieri, D.C.1
-
52
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
-
53
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
-
54
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
-
62
-
-
0030614915
-
XL-Bak peptide complex: Recognition between regulators of apoptosis
-
(1997)
Science
, vol.275
, pp. 983-986
-
-
Sattler, M.1
-
66
-
-
0035147650
-
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 183-192
-
-
Tzung, S.1
-
67
-
-
0032752063
-
Cellular survival: A play in three Akts
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.1
-
69
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of Ikappa B kinase
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
-
72
-
-
0000186923
-
Calcineurin promotes apoptosis by dephosphorylating BAD
-
(1998)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.-G.1
-
73
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-κB
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
|