메뉴 건너뛰기




Volumn 122, Issue 4, 2004, Pages 339-352

Reactive oxygen species in vascular biology: Implications in hypertension

Author keywords

Atherosclerosis; Hypertension; NAD(P)H oxidase; Nitric oxide synthase; Nox; Redox signaling; Superoxide; Xanthine oxidase

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIOXIDANT; ARACHIDONIC ACID; CATALASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; G PROTEIN COUPLED RECEPTOR; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; PHOSPHOLIPASE C; PHOSPHOLIPASE D; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SCAVENGER; SCLEROPROTEIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOREDOXIN; XANTHINE OXIDASE;

EID: 8644277006     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-004-0696-7     Document Type: Review
Times cited : (539)

References (176)
  • 2
    • 0028821016 scopus 로고
    • Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: A new perspective
    • Alexander RW (1995) Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension 25:155-161
    • (1995) Hypertension , vol.25 , pp. 155-161
    • Alexander, R.W.1
  • 3
    • 0033527374 scopus 로고    scopus 로고
    • Expression of NADH/ NADPH oxidase p22phox in human coronary arteries
    • Azumimi H, Inoue N, Takeshita S (1999) Expression of NADH/ NADPH oxidase p22phox in human coronary arteries. Circulation 100:1494-1498
    • (1999) Circulation , vol.100 , pp. 1494-1498
    • Azumimi, H.1    Inoue, N.2    Takeshita, S.3
  • 5
    • 0037228474 scopus 로고    scopus 로고
    • Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin
    • Bagi Z, Koller A (2003) Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin. J Vasc Res 40:47-57
    • (2003) J Vasc Res , vol.40 , pp. 47-57
    • Bagi, Z.1    Koller, A.2
  • 6
    • 0038789165 scopus 로고    scopus 로고
    • Two novel proteins activate superoxide generation by the NADPH oxidase Nox1
    • Banfi B, Clark RA, Steger K, Krause K-H (2003) Two novel proteins activate superoxide generation by the NADPH oxidase Nox1. J Biol Chem 278:3510-3513
    • (2003) J Biol Chem , vol.278 , pp. 3510-3513
    • Banfi, B.1    Clark, R.A.2    Steger, K.3    Krause, K.-H.4
  • 7
    • 0037154308 scopus 로고    scopus 로고
    • Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
    • Bendall JK, Cave AC, Heymes C, Gall N, Shah AM (2002) Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 105:293-296
    • (2002) Circulation , vol.105 , pp. 293-296
    • Bendall, J.K.1    Cave, A.C.2    Heymes, C.3    Gall, N.4    Shah, A.M.5
  • 9
    • 0034625073 scopus 로고    scopus 로고
    • Investigation into the sources of superoxide in human blood vessels: Angiotensin II increases superoxide production in human internal mammary arteries
    • Berry C, Hamilton CA, Brosnan MJ, Magill FG, Berg GA, McMurray JJ, Dominiczak AF (2000) Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation 101:2206-2212
    • (2000) Circulation , vol.101 , pp. 2206-2212
    • Berry, C.1    Hamilton, C.A.2    Brosnan, M.J.3    Magill, F.G.4    Berg, G.A.5    McMurray, J.J.6    Dominiczak, A.F.7
  • 13
    • 0035083871 scopus 로고    scopus 로고
    • Dietary modulation of endothelial function: Implications for cardiovascular disease
    • Brown AA, Hu FB (2001) Dietary modulation of endothelial function: implications for cardiovascular disease. Am J Clin Nutr. 73:673-686
    • (2001) Am J Clin Nutr. , vol.73 , pp. 673-686
    • Brown, A.A.1    Hu, F.B.2
  • 14
    • 0042379916 scopus 로고    scopus 로고
    • The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
    • Cai H, Griendling KK, Harrison DG (2003) The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 24:471-478
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 471-478
    • Cai, H.1    Griendling, K.K.2    Harrison, D.G.3
  • 15
    • 0141464922 scopus 로고    scopus 로고
    • Oxidative stress and heart disease: Cardiac dysfunction, nutrition, and gene therapy
    • Cantor EJ, Mancini EV, Seth R, Yao XH, Netticadan T (2003) Oxidative stress and heart disease: cardiac dysfunction, nutrition, and gene therapy. Curr Hypertens Rep 5:215-220
    • (2003) Curr Hypertens Rep , vol.5 , pp. 215-220
    • Cantor, E.J.1    Mancini, E.V.2    Seth, R.3    Yao, X.H.4    Netticadan, T.5
  • 17
    • 0036908442 scopus 로고    scopus 로고
    • Mechanisms of superoxide production in human blood vessels: Relationship to endothelial dysfunction, clinical and genetic risk factors
    • Channon KM, Guzik TJ (2002) Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors. J Physiol Pharmacol 53:515-524
    • (2002) J Physiol Pharmacol , vol.53 , pp. 515-524
    • Channon, K.M.1    Guzik, T.J.2
  • 18
    • 0033523401 scopus 로고    scopus 로고
    • Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: A randomized trial
    • Chappell LC, Seed PT, Briley AL, Kelly FJ, Lee R, et al (1999) Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomized trial. Lancet 354:810-815
    • (1999) Lancet , vol.354 , pp. 810-815
    • Chappell, L.C.1    Seed, P.T.2    Briley, A.L.3    Kelly, F.J.4    Lee, R.5
  • 19
    • 0035460097 scopus 로고    scopus 로고
    • Antioxidant effects of vitamins C and e are associated with altered activation of vascular NAD(P)H oxidase and superoxide dismutase in stroke-prone SHR
    • Chen X, Touyz RM, Park JB, Schiffrin EL (2001) Antioxidant effects of vitamins C and E are associated with altered activation of vascular NAD(P)H oxidase and superoxide dismutase in stroke-prone SHR. Hypertension 38:606-611
    • (2001) Hypertension , vol.38 , pp. 606-611
    • Chen, X.1    Touyz, R.M.2    Park, J.B.3    Schiffrin, E.L.4
  • 20
    • 0035897653 scopus 로고    scopus 로고
    • Homologs of gp91phox: Cloning and tissue expression of Nox3, Nox4, and Nox5
    • Cheng G, Cao Z, Xu X, van Meir EG, Lambeth JD (2001) Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. Gene 269:131-140
    • (2001) Gene , vol.269 , pp. 131-140
    • Cheng, G.1    Cao, Z.2    Xu, X.3    Van Meir, E.G.4    Lambeth, J.D.5
  • 21
    • 0642276003 scopus 로고    scopus 로고
    • Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction
    • Chiarugi P, Cirri P (2003) Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction. Trends Biochem Sci 28:509-514
    • (2003) Trends Biochem Sci , vol.28 , pp. 509-514
    • Chiarugi, P.1    Cirri, P.2
  • 22
    • 23444436348 scopus 로고
    • Role of superoxide anions in the mediation of endothelium-dependent contractions
    • Cosentino F, Sill JC, Katusic ZS (1994) Role of superoxide anions in the mediation of endothelium-dependent contractions. Hypertension 23:229-235
    • (1994) Hypertension , vol.23 , pp. 229-235
    • Cosentino, F.1    Sill, J.C.2    Katusic, Z.S.3
  • 25
    • 0033959248 scopus 로고    scopus 로고
    • Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids
    • Dandona P, Karne R, Ghanim H, Hamouda W, Aljada A, Magsino CH (2000) Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids. Circulation 101:122-124
    • (2000) Circulation , vol.101 , pp. 122-124
    • Dandona, P.1    Karne, R.2    Ghanim, H.3    Hamouda, W.4    Aljada, A.5    Magsino, C.H.6
  • 27
    • 0029144638 scopus 로고
    • Nitric oxide and oxygen radicals, a question of balance
    • Darley-Usmar V, Wiseman H, Halliwell B (1995) Nitric oxide and oxygen radicals, a question of balance. FEBS Lett 369:13-15
    • (1995) FEBS Lett , vol.369 , pp. 13-15
    • Darley-Usmar, V.1    Wiseman, H.2    Halliwell, B.3
  • 29
    • 0030054867 scopus 로고    scopus 로고
    • Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox
    • De Leo FR, Ulman KV, Davis AR,Jutila KL, Quinn MT (1996) Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox. J Biol Chem 271:17013-17020
    • (1996) J Biol Chem , vol.271 , pp. 17013-17020
    • De Leo, F.R.1    Ulman, K.V.2    Davis, A.R.3    Jutila, K.L.4    Quinn, M.T.5
  • 31
    • 0034083227 scopus 로고    scopus 로고
    • Role of oxidative stress in cardiovascular diseases
    • Dhalla SN, Temsah RM, Netticadan T (2000) Role of oxidative stress in cardiovascular diseases. J Hypertens 18:655-673
    • (2000) J Hypertens , vol.18 , pp. 655-673
    • Dhalla, S.N.1    Temsah, R.M.2    Netticadan, T.3
  • 33
    • 1542270216 scopus 로고    scopus 로고
    • The A1166C polymorphism of the AT1 receptor gene is associated with collagen type I synthesis and myocardial stiffness in hypertensives
    • Diez J, Laviades C, Orbe J, Zalba G, Lopez B, Gonzalez A, Mayor G, Paramo JA, Beloqui O (2003) The A1166C polymorphism of the AT1 receptor gene is associated with collagen type I synthesis and myocardial stiffness in hypertensives. J Hypertens 21:2085-2092
    • (2003) J Hypertens , vol.21 , pp. 2085-2092
    • Diez, J.1    Laviades, C.2    Orbe, J.3    Zalba, G.4    Lopez, B.5    Gonzalez, A.6    Mayor, G.7    Paramo, J.A.8    Beloqui, O.9
  • 34
    • 0035317895 scopus 로고    scopus 로고
    • Prospects for the use of antioxidant therapy in hypertension
    • Digiesi D, Lenuzza M, Digiese G (2001) Prospects for the use of antioxidant therapy in hypertension. Ann Ital Med Int 16:93-100
    • (2001) Ann Ital Med Int , vol.16 , pp. 93-100
    • Digiesi, D.1    Lenuzza, M.2    Digiese, G.3
  • 35
    • 0035112988 scopus 로고    scopus 로고
    • Lead-induced hypertension. III. Increased hydroxyl radical production
    • Ding Y, Gonick HC, Vaziri ND, Liang K, Wei L (2001) Lead-induced hypertension. III. Increased hydroxyl radical production. Am J Hypertens 14:169-173
    • (2001) Am J Hypertens , vol.14 , pp. 169-173
    • Ding, Y.1    Gonick, H.C.2    Vaziri, N.D.3    Liang, K.4    Wei, L.5
  • 37
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W (2001) Free radicals in the physiological control of cell function. Physiol Rev 82:47-95
    • (2001) Physiol Rev , vol.82 , pp. 47-95
    • Droge, W.1
  • 40
    • 0036182380 scopus 로고    scopus 로고
    • Calcium and oxidative stress: From cell signaling to cell death
    • Ermak G, Davies KJA (2001) Calcium and oxidative stress: from cell signaling to cell death. Mol Immunol 38:713-721
    • (2001) Mol Immunol , vol.38 , pp. 713-721
    • Ermak, G.1    Davies, K.J.A.2
  • 41
    • 0037340080 scopus 로고    scopus 로고
    • Characterization of an animal model of postmenopausal hypertension in spontaneously hypertensive rats
    • Fortepiani LA, Zhang H, Racusen L, Roberts LJ II, Reckelhoff JF (2003) Characterization of an animal model of postmenopausal hypertension in spontaneously hypertensive rats. Hypertension 41:640-645
    • (2003) Hypertension , vol.41 , pp. 640-645
    • Fortepiani, L.A.1    Zhang, H.2    Racusen, L.3    Roberts II, L.J.4    Reckelhoff, J.F.5
  • 42
    • 0034043751 scopus 로고    scopus 로고
    • Effect of vitamin C on ambulatory blood pressure and plasma lipids in older patients
    • Fotheby MD, Williams JC, Forster LA, Craner P, Ferns GA (2000) Effect of vitamin C on ambulatory blood pressure and plasma lipids in older patients. J Hypertens 18:411-415
    • (2000) J Hypertens , vol.18 , pp. 411-415
    • Fotheby, M.D.1    Williams, J.C.2    Forster, L.A.3    Craner, P.4    Ferns, G.A.5
  • 43
    • 0020427486 scopus 로고
    • Biology of disease: Free radicals and tissue injury
    • Freeman BA, Crapo JD (1982) Biology of disease: free radicals and tissue injury. Lab Invest 47:412-426
    • (1982) Lab Invest , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 44
    • 1842845223 scopus 로고    scopus 로고
    • Very high alpha-tocopherol diet diminishes oxidative stress and hypercoagulation in hypertensive rats but not in normotensive rats
    • Frenoux JM, Noirot B, Prost ED, Madani S, Blond JP, Belleville JL, Prost JL (2002) Very high alpha-tocopherol diet diminishes oxidative stress and hypercoagulation in hypertensive rats but not in normotensive rats. Med Sci Monit 8:BR401-BR407
    • (2002) Med Sci Monit , vol.8
    • Frenoux, J.M.1    Noirot, B.2    Prost, E.D.3    Madani, S.4    Blond, J.P.5    Belleville, J.L.6    Prost, J.L.7
  • 45
    • 0030806863 scopus 로고    scopus 로고
    • Superoxide anion radical, superoxide dismutases, and related matters
    • Fridovich I (1997) Superoxide anion radical, superoxide dismutases, and related matters. J Biol Chem 272:18515-18517
    • (1997) J Biol Chem , vol.272 , pp. 18515-18517
    • Fridovich, I.1
  • 46
    • 0030895186 scopus 로고    scopus 로고
    • Combination oral antioxidant supplementation reduces blood pressure
    • Lond
    • Galley HF, Thornton J, Howdle PD, Walker BE, Webster NR (1997) Combination oral antioxidant supplementation reduces blood pressure. Clin Sci (Lond) 92:361-365
    • (1997) Clin Sci , vol.92 , pp. 361-365
    • Galley, H.F.1    Thornton, J.2    Howdle, P.D.3    Walker, B.E.4    Webster, N.R.5
  • 47
    • 0035671492 scopus 로고    scopus 로고
    • Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production
    • Gao YJ, Lee RM (2001) Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. Br J Pharmacol 134:1639-1646
    • (2001) Br J Pharmacol , vol.134 , pp. 1639-1646
    • Gao, Y.J.1    Lee, R.M.2
  • 50
    • 0035816732 scopus 로고    scopus 로고
    • Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase
    • Gorlach A, Diebold I, Schini-Kerth VB, Berchner-Pfannschmidt U, Roth U, Brandes RP, Kietzmann T, Busse R (2001) Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: role of the p22(phox)-containing NADPH oxidase. Circ Res 89:47-54
    • (2001) Circ Res , vol.89 , pp. 47-54
    • Gorlach, A.1    Diebold, I.2    Schini-Kerth, V.B.3    Berchner-Pfannschmidt, U.4    Roth, U.5    Brandes, R.P.6    Kietzmann, T.7    Busse, R.8
  • 51
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW (1994) Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74:1141-1148
    • (1994) Circ Res , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 52
    • 0033781454 scopus 로고    scopus 로고
    • Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology
    • Griendling KK, Sorescu D, Lassegue B, Ushio-Fukai M (2000a) Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler Thromb Vasc Biol 20:2175-2183
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2175-2183
    • Griendling, K.K.1    Sorescu, D.2    Lassegue, B.3    Ushio-Fukai, M.4
  • 53
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M (2000b) NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86:494-501
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 54
    • 0038718531 scopus 로고    scopus 로고
    • Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species
    • Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, Drexler H, Schieffer B (2003) Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species. Circ Res 92:e80-e86
    • (2003) Circ Res , vol.92
    • Grote, K.1    Flach, I.2    Luchtefeld, M.3    Akin, E.4    Holland, S.M.5    Drexler, H.6    Schieffer, B.7
  • 55
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ratnatunga C, Pillai R, Channon KM (2002) Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 105:1656-1562
    • (2002) Circulation , vol.105 , pp. 1656-11562
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 56
    • 0036829062 scopus 로고    scopus 로고
    • Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
    • Haddad JJ (2002) Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cell Signal 14:879-897
    • (2002) Cell Signal , vol.14 , pp. 879-897
    • Haddad, J.J.1
  • 57
    • 0032823769 scopus 로고    scopus 로고
    • Antioxidant defence mechanisms: From the beginning to the end (of the beginning)
    • Halliwell B (1999) Antioxidant defence mechanisms: from the beginning to the end (of the beginning). Free Radic Res 31:261-272
    • (1999) Free Radic Res , vol.31 , pp. 261-272
    • Halliwell, B.1
  • 58
    • 0037458619 scopus 로고    scopus 로고
    • Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
    • Han D, Antunes F, Canali R, Rettori D, Cadenas E (2003) Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem 278:5557-5563
    • (2003) J Biol Chem , vol.278 , pp. 5557-5563
    • Han, D.1    Antunes, F.2    Canali, R.3    Rettori, D.4    Cadenas, E.5
  • 59
    • 0030711684 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of endothelial cell dysfunction
    • Harrison DG (1997) Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest 1997:2153-2157
    • (1997) J Clin Invest , vol.1997 , pp. 2153-2157
    • Harrison, D.G.1
  • 60
    • 0036100972 scopus 로고    scopus 로고
    • Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
    • Higashi Y, Sasaki S, Nakagawa K, Fukuda Y, Matsuura H, Oshima T, Chayama K (2002a) Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals. Am J Hypertens 15:326-332
    • (2002) Am J Hypertens , vol.15 , pp. 326-332
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Fukuda, Y.4    Matsuura, H.5    Oshima, T.6    Chayama, K.7
  • 61
    • 0037142088 scopus 로고    scopus 로고
    • Endothelial function and oxidative stress in renovascular hypertension
    • Higashi Y, Sasaki S, Nakagawa K, et al (2002b) Endothelial function and oxidative stress in renovascular hypertension. N Engl J Med 346:1954-1962
    • (2002) N Engl J Med , vol.346 , pp. 1954-1962
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3
  • 63
    • 0037342599 scopus 로고    scopus 로고
    • Contributions of 20-HETE to the antihypertensive effects of Tempol in Dahl salt-sensitive rats
    • Hoagland KM, Maier KG, Roman RJ (2003) Contributions of 20-HETE to the antihypertensive effects of Tempol in Dahl salt-sensitive rats. Hypertension 41:697-702
    • (2003) Hypertension , vol.41 , pp. 697-702
    • Hoagland, K.M.1    Maier, K.G.2    Roman, R.J.3
  • 64
    • 0035726142 scopus 로고    scopus 로고
    • Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats
    • Hong HJ, Hsiao G, Cheng TH, Yen MH (2001) Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats. Hypertension 38:1044-1048
    • (2001) Hypertension , vol.38 , pp. 1044-1048
    • Hong, H.J.1    Hsiao, G.2    Cheng, T.H.3    Yen, M.H.4
  • 65
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin e supplementation and cardiovascular events in high risk patients
    • HOPE Investigators (2000) Vitamin E supplementation and cardiovascular events in high risk patients. N Engl J Med 342:154-160
    • (2000) N Engl J Med , vol.342 , pp. 154-160
  • 66
    • 33750845370 scopus 로고    scopus 로고
    • Expression of phagocyte NADPH oxidase components in human endothelial cells
    • Jones A, O'Donnell VB, Wood JD (1996) Expression of phagocyte NADPH oxidase components in human endothelial cells. Am J Physiol H1626-H1634
    • (1996) Am J Physiol
    • Jones, A.1    O'Donnell, V.B.2    Wood, J.D.3
  • 68
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension. Role of endothelium
    • Kerr S, Brosnan J, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA (1999) Superoxide anion production is increased in a model of genetic hypertension. Role of endothelium. Hypertension 33:1353-1358
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 69
    • 0035799105 scopus 로고    scopus 로고
    • Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: A prospective population study
    • Khaw K-T, Bingham S, Welch A, Luben R, Wareham N, Oakes S, et al (2001) Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. Lancet 357:657-663
    • (2001) Lancet , vol.357 , pp. 657-663
    • Khaw, K.-T.1    Bingham, S.2    Welch, A.3    Luben, R.4    Wareham, N.5    Oakes, S.6
  • 71
    • 0031850917 scopus 로고    scopus 로고
    • Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension
    • Kristal B, Shurta-Swirrski R, Chezar J (1998) Participation of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation in patients with essential hypertension. Am J Hypertens 11:921-928
    • (1998) Am J Hypertens , vol.11 , pp. 921-928
    • Kristal, B.1    Shurta-Swirrski, R.2    Chezar, J.3
  • 72
    • 0033695425 scopus 로고    scopus 로고
    • Plasma hydrogen peroxide production in human essential hypertension: Role of heredity, gender, and ethnicity
    • Lacy F, Kailasam MT, O'Connor DT, Schmid-Schonbein GW, Parmer RJ (2000) Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity. Hypertension 36:878-884
    • (2000) Hypertension , vol.36 , pp. 878-884
    • Lacy, F.1    Kailasam, M.T.2    O'Connor, D.T.3    Schmid-Schonbein, G.W.4    Parmer, R.J.5
  • 73
    • 0034764030 scopus 로고    scopus 로고
    • Oxidative stress and vascular damage in hypertension
    • Landmesser U, Harrison DG (2001) Oxidative stress and vascular damage in hypertension. Coron Artery Dis 12:455-461
    • (2001) Coron Artery Dis , vol.12 , pp. 455-461
    • Landmesser, U.1    Harrison, D.G.2
  • 76
    • 0042810670 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidases: Specific features, expression, and regulation
    • Lassegue B, Clempus RE (2003) Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Regul Integr Comp Physiol 285:R277-R297
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Lassegue, B.1    Clempus, R.E.2
  • 77
    • 0035844030 scopus 로고    scopus 로고
    • Novel gp91(phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
    • Lassegue B, Sorescu D, Szocs K, Yin Q, Akers M, Zhang Y, Grant SL, Lambeth JD, Griendling KK (2001) Novel gp91(phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res 88:888-894
    • (2001) Circ Res , vol.88 , pp. 888-894
    • Lassegue, B.1    Sorescu, D.2    Szocs, K.3    Yin, Q.4    Akers, M.5    Zhang, Y.6    Grant, S.L.7    Lambeth, J.D.8    Griendling, K.K.9
  • 79
    • 0037108204 scopus 로고    scopus 로고
    • 2 regulates the activation of distinct MAPK pathways
    • 2 regulates the activation of distinct MAPK pathways. Free Radic Biol Med 33:1121-1132
    • (2002) Free Radic Biol Med , vol.33 , pp. 1121-1132
    • Lee, K.1    Esselman, W.J.2
  • 80
    • 0032546955 scopus 로고    scopus 로고
    • Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor
    • Lee SR, Kwon KS, Kim SR, Rhee SG (1998) Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J Biol Chem 273:15366-15372
    • (1998) J Biol Chem , vol.273 , pp. 15366-15372
    • Lee, S.R.1    Kwon, K.S.2    Kim, S.R.3    Rhee, S.G.4
  • 82
    • 0037331766 scopus 로고    scopus 로고
    • Neutrophil activation and production of reactive oxygen species in pre-eclampsia
    • Lee VM, Quinn PA, Jennings SC, Ng LL (2003) Neutrophil activation and production of reactive oxygen species in pre-eclampsia. J Hypertens 21:395-402
    • (2003) J Hypertens , vol.21 , pp. 395-402
    • Lee, V.M.1    Quinn, P.A.2    Jennings, S.C.3    Ng, L.L.4
  • 83
    • 0002501831 scopus 로고    scopus 로고
    • Interactions between the components of the human NADPH oxidase: A review about the intrigues in the phox family
    • Leusen JHW, Verhoeven AJ, Roos D (1996) Interactions between the components of the human NADPH oxidase: a review about the intrigues in the phox family. Front Biosci 1:72-90
    • (1996) Front Biosci , vol.1 , pp. 72-90
    • Leusen, J.H.W.1    Verhoeven, A.J.2    Roos, D.3
  • 84
    • 0037205457 scopus 로고    scopus 로고
    • Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells
    • Li JM, Shah AM (2002) Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem 277:19952-19960
    • (2002) J Biol Chem , vol.277 , pp. 19952-19960
    • Li, J.M.1    Shah, A.M.2
  • 85
    • 0037809230 scopus 로고    scopus 로고
    • Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit
    • Li JM, Shah AM (2003) Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit. J Biol Chem 278:12094-12100
    • (2003) J Biol Chem , vol.278 , pp. 12094-12100
    • Li, J.M.1    Shah, A.M.2
  • 87
    • 0037465438 scopus 로고    scopus 로고
    • Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension
    • Li L, Fink GD, Watts SW, Northcott CA, Galligan JJ, Pagano PJ, Chen AF (2003a) Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation 107:1053-1058
    • (2003) Circulation , vol.107 , pp. 1053-1058
    • Li, L.1    Fink, G.D.2    Watts, S.W.3    Northcott, C.A.4    Galligan, J.J.5    Pagano, P.J.6    Chen, A.F.7
  • 88
    • 0344430160 scopus 로고    scopus 로고
    • Hydrogen peroxide induces apoptosis in cerebral vascular smooth muscle cells: Possible relation to neurodegenerative diseases and strokes
    • Li J, Li W, Su J, Liu W, Altura BT, Altura BM (2003b) Hydrogen peroxide induces apoptosis in cerebral vascular smooth muscle cells: possible relation to neurodegenerative diseases and strokes. Brain Res Bull 62:101-106
    • (2003) Brain Res Bull , vol.62 , pp. 101-106
    • Li, J.1    Li, W.2    Su, J.3    Liu, W.4    Altura, B.T.5    Altura, B.M.6
  • 90
    • 0030948345 scopus 로고    scopus 로고
    • Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: Tetrahydrobiopterin binding kinetics and role of haem in dimerization
    • List BM, Klosch B, Volker C, Gorren AC, Sessa WC, Werner ER, Kukovetz WR, Schmidt K, Mayer B (1997) Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization. Biochem J 323:159-165
    • (1997) Biochem J , vol.323 , pp. 159-165
    • List, B.M.1    Klosch, B.2    Volker, C.3    Gorren, A.C.4    Sessa, W.C.5    Werner, E.R.6    Kukovetz, W.R.7    Schmidt, K.8    Mayer, B.9
  • 92
    • 0034190304 scopus 로고    scopus 로고
    • Calcium signaling and oxidant stress in the vasculature
    • Lounsbury KM, Hu Q, Ziegelstein RC (2000) Calcium signaling and oxidant stress in the vasculature. Free Radic Biol Med 28:1362-1369
    • (2000) Free Radic Biol Med , vol.28 , pp. 1362-1369
    • Lounsbury, K.M.1    Hu, Q.2    Ziegelstein, R.C.3
  • 93
    • 0035092984 scopus 로고    scopus 로고
    • Mechanisms and cardiovascular damage in hypertension
    • Luft FC (2001) Mechanisms and cardiovascular damage in hypertension. Hypertension 37:594-598
    • (2001) Hypertension , vol.37 , pp. 594-598
    • Luft, F.C.1
  • 94
    • 0344873104 scopus 로고    scopus 로고
    • Renal and vascular oxidative stress and salt-sensitivity of arterial pressure
    • Manning RD Jr, Meng S, Tian N (2003) Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. Acta Physiol Scand 179:243-250
    • (2003) Acta Physiol Scand , vol.179 , pp. 243-250
    • Manning Jr., R.D.1    Meng, S.2    Tian, N.3
  • 96
    • 0030770395 scopus 로고    scopus 로고
    • Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells
    • Marumo T, Schini-Kerth VB, Fisslthaler B, Busse R (1997) Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells. Circulation 96:2361-2367
    • (1997) Circulation , vol.96 , pp. 2361-2367
    • Marumo, T.1    Schini-Kerth, V.B.2    Fisslthaler, B.3    Busse, R.4
  • 97
    • 0036184190 scopus 로고    scopus 로고
    • Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
    • Meng TC, Fukada T, Tonks NK (2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol Cell 9:387-399
    • (2002) Mol Cell , vol.9 , pp. 387-399
    • Meng, T.C.1    Fukada, T.2    Tonks, N.K.3
  • 98
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • Milstien S, Katusic Z (1999) Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263:681-684
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 99
    • 0037180471 scopus 로고    scopus 로고
    • Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease
    • Minuz P, Patrignani P, Gaino S, Degan M, Menapace L, Tommasoli R (2002) Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. Circulation 106:2800-2805
    • (2002) Circulation , vol.106 , pp. 2800-2805
    • Minuz, P.1    Patrignani, P.2    Gaino, S.3    Degan, M.4    Menapace, L.5    Tommasoli, R.6
  • 100
    • 0346333139 scopus 로고    scopus 로고
    • Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition-induced hypertension
    • Mitchell BM, Dorrance AM, Ergul A, Webb RC (2004) Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition-induced hypertension. J Cardiovasc Pharmacol 43:93-98
    • (2004) J Cardiovasc Pharmacol , vol.43 , pp. 93-98
    • Mitchell, B.M.1    Dorrance, A.M.2    Ergul, A.3    Webb, R.C.4
  • 101
    • 0038363762 scopus 로고    scopus 로고
    • Preliminary characterisation of the promoter of the human p22(phox) gene: Identification of a new polymorphism associated with hypertension
    • Moreno MU, San Jose G, Orbe J, Paramo JA, Beloqui O, Diez J, Zalba G (2003) Preliminary characterisation of the promoter of the human p22(phox) gene: identification of a new polymorphism associated with hypertension. FEBS Lett 542:27-31
    • (2003) FEBS Lett , vol.542 , pp. 27-31
    • Moreno, M.U.1    San Jose, G.2    Orbe, J.3    Paramo, J.A.4    Beloqui, O.5    Diez, J.6    Zalba, G.7
  • 102
    • 0036900442 scopus 로고    scopus 로고
    • Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes
    • Mullan B, Young IS, Fee H, McCance DR (2002) Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes. Hypertension 40:804-809
    • (2002) Hypertension , vol.40 , pp. 804-809
    • Mullan, B.1    Young, I.S.2    Fee, H.3    McCance, D.R.4
  • 104
    • 0038353477 scopus 로고    scopus 로고
    • Role of the endothelium and nitric oxide synthases in modulating superoxide formation induced by endotoxin and cytokines in porcine pulmonary arteries
    • Muzaffar S, Jeremy JY, Angelini GD, Stuart-Smith K, Shukla N (2003) Role of the endothelium and nitric oxide synthases in modulating superoxide formation induced by endotoxin and cytokines in porcine pulmonary arteries. Thorax 58:598-604
    • (2003) Thorax , vol.58 , pp. 598-604
    • Muzaffar, S.1    Jeremy, J.Y.2    Angelini, G.D.3    Stuart-Smith, K.4    Shukla, N.5
  • 106
    • 17744377600 scopus 로고    scopus 로고
    • The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and α1-blockers
    • Ohtahara A, Hisatome I, Yamamoto Y, Furuse M, Sonoyama K, Furuse Y (2001) The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and α1-blockers. J Hypertens 19:575-582
    • (2001) J Hypertens , vol.19 , pp. 575-582
    • Ohtahara, A.1    Hisatome, I.2    Yamamoto, Y.3    Furuse, M.4    Sonoyama, K.5    Furuse, Y.6
  • 107
    • 0036155396 scopus 로고    scopus 로고
    • Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats
    • Park JB, Touyz RM, Chen X, Schiffrin EL (2002) Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats. Am J Hypertens 15:78-84
    • (2002) Am J Hypertens , vol.15 , pp. 78-84
    • Park, J.B.1    Touyz, R.M.2    Chen, X.3    Schiffrin, E.L.4
  • 110
    • 0042266230 scopus 로고    scopus 로고
    • AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: Role of the AT1 receptor and NADPH oxidase
    • Privratsky JR, Wold LE, Sowers JR, Quinn MT, Ren J (2003) AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase. Hypertension 42:206-212
    • (2003) Hypertension , vol.42 , pp. 206-212
    • Privratsky, J.R.1    Wold, L.E.2    Sowers, J.R.3    Quinn, M.T.4    Ren, J.5
  • 111
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: Contribution to alterations of vasomotor tone
    • Rajagopalan S, Kurz S, Munzel T (1996a) Angiotensin II mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest 97:1916-1923
    • (1996) J Clin Invest , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Munzel, T.3
  • 112
    • 10544246489 scopus 로고    scopus 로고
    • Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro
    • Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS (1996b) Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. J Clin Invest 98:2572-2579
    • (1996) J Clin Invest , vol.98 , pp. 2572-2579
    • Rajagopalan, S.1    Meng, X.P.2    Ramasamy, S.3    Harrison, D.G.4    Galis, Z.S.5
  • 113
    • 0026515446 scopus 로고
    • Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression
    • Rao GN, Berk BC (1992) Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression. Circ Res 70:593-599
    • (1992) Circ Res , vol.70 , pp. 593-599
    • Rao, G.N.1    Berk, B.C.2
  • 114
    • 0036911138 scopus 로고    scopus 로고
    • Hydrogen peroxide as second messenger in lymphocyte activation
    • Reth M (2002) Hydrogen peroxide as second messenger in lymphocyte activation. Nat Immunol 3:1129-1134
    • (2002) Nat Immunol , vol.3 , pp. 1129-1134
    • Reth, M.1
  • 115
    • 0036924243 scopus 로고    scopus 로고
    • The reactive adventitia: Fibroblast oxidase in vascular function
    • Rey FE, Pagano PJ (2002) The reactive adventitia: fibroblast oxidase in vascular function. Arterioscler Thromb Vasc Biol 22:1962-1971
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1962-1971
    • Rey, F.E.1    Pagano, P.J.2
  • 116
    • 0033209906 scopus 로고    scopus 로고
    • Role of angiotensin and oxidative stress in essential hypertension
    • Romero JC, Reckelhoff JF (1999) Role of angiotensin and oxidative stress in essential hypertension. Hypertension 34:943-949
    • (1999) Hypertension , vol.34 , pp. 943-949
    • Romero, J.C.1    Reckelhoff, J.F.2
  • 119
    • 0034873185 scopus 로고    scopus 로고
    • Reactive oxygen species as intracellular messengers during cell growth and differentiation
    • Sauer H, Wartenberg M, Hescheler J (2001) Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11:173-186
    • (2001) Cell Physiol Biochem , vol.11 , pp. 173-186
    • Sauer, H.1    Wartenberg, M.2    Hescheler, J.3
  • 120
    • 0034937504 scopus 로고    scopus 로고
    • NADH/NADPH oxidase p22 phox gene polymorphism is associated with improved coronary endothelial vasodilator function
    • Schachinger V, Britten MB, Dimmeler S, Zeiher AM (2001) NADH/NADPH oxidase p22 phox gene polymorphism is associated with improved coronary endothelial vasodilator function. Fur Heart J 22:96-101
    • (2001) Fur Heart J , vol.22 , pp. 96-101
    • Schachinger, V.1    Britten, M.B.2    Dimmeler, S.3    Zeiher, A.M.4
  • 121
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple
    • Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/ glutathione couple. Free Radic Biol Med 30:1191-1212
    • (2001) Free Radic Biol Med , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 122
    • 0031926961 scopus 로고    scopus 로고
    • Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic. Role of nitric oxide
    • Schnackenberg CG, Welch W, Wilcox CS (1999) Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic. Role of nitric oxide. Hypertension 32:59-64
    • (1999) Hypertension , vol.32 , pp. 59-64
    • Schnackenberg, C.G.1    Welch, W.2    Wilcox, C.S.3
  • 123
    • 1442348092 scopus 로고    scopus 로고
    • Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: A study in human and porcine arteries
    • Schuijt MP, Tom B, De Vries R, Saxena PR, Sluiter W, Van Kats JP, Danser AH (2003) Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries. J Hypertens 21:2335-2344
    • (2003) J Hypertens , vol.21 , pp. 2335-2344
    • Schuijt, M.P.1    Tom, B.2    De Vries, R.3    Saxena, P.R.4    Sluiter, W.5    Van Kats, J.P.6    Danser, A.H.7
  • 125
    • 0030175709 scopus 로고    scopus 로고
    • Probucol suppresses oxidant stress in hypertensive arteries. Immunohistochemical evidence
    • Sharma RC, Hodis HN, Mack WJ (1996) Probucol suppresses oxidant stress in hypertensive arteries. Immunohistochemical evidence. Am J Hypertens 9:577-590
    • (1996) Am J Hypertens , vol.9 , pp. 577-590
    • Sharma, R.C.1    Hodis, H.N.2    Mack, W.J.3
  • 126
    • 0033068858 scopus 로고    scopus 로고
    • Reactive oxygen species and the control of vasomotor tone
    • Somers MJ, Harrison DG (1999) Reactive oxygen species and the control of vasomotor tone. Curr Hypertens Rep 1:102-108
    • (1999) Curr Hypertens Rep , vol.1 , pp. 102-108
    • Somers, M.J.1    Harrison, D.G.2
  • 128
    • 0036591604 scopus 로고    scopus 로고
    • Increasing plasma fatty acids elevates F2-isoprostanes in humans: Implications for the cardiovascular risk factor cluster
    • Stojiljkovic MP, Lopes HF, Zhang D, Morrow JD, Goodfriend TL, Egan BM (2002) Increasing plasma fatty acids elevates F2-isoprostanes in humans: implications for the cardiovascular risk factor cluster. J Hypertens 20:1215-1221
    • (2002) J Hypertens , vol.20 , pp. 1215-1221
    • Stojiljkovic, M.P.1    Lopes, H.F.2    Zhang, D.3    Morrow, J.D.4    Goodfriend, T.L.5    Egan, B.M.6
  • 129
    • 0028805056 scopus 로고
    • The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase
    • Stralin P, Karlsson K, Johannson BO, Marklund SL (1995) The interstitium of the human arterial wall contains very large amounts of extracellular superoxide dismutase. Arterioscler Thromb Vasc Biol 15:2032-2036
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 2032-2036
    • Stralin, P.1    Karlsson, K.2    Johannson, B.O.3    Marklund, S.L.4
  • 130
    • 0038893696 scopus 로고    scopus 로고
    • The inflammatory aspect of the microcirculation in hypertension: Oxidative stress, leukocytes/endothelial interaction, apoptosis
    • Suematsu M, Suzuki H, Delano FA, Schmid-Schonbein GW (2002) The inflammatory aspect of the microcirculation in hypertension: oxidative stress, leukocytes/endothelial interaction, apoptosis. Microcirculation 9:259-276
    • (2002) Microcirculation , vol.9 , pp. 259-276
    • Suematsu, M.1    Suzuki, H.2    Delano, F.A.3    Schmid-Schonbein, G.W.4
  • 131
    • 0033517275 scopus 로고    scopus 로고
    • Cell transformation by the superoxide-generating Mox-1
    • Suh YA, Arnold RS, Lassegue B (1999) Cell transformation by the superoxide-generating Mox-1. Nature 410:79-82
    • (1999) Nature , vol.410 , pp. 79-82
    • Suh, Y.A.1    Arnold, R.S.2    Lassegue, B.3
  • 132
    • 0037432615 scopus 로고    scopus 로고
    • Multiple pathways of peroxynitrite cytotoxicity
    • Szabo C (2003) Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett 140:105-112
    • (2003) Toxicol Lett , vol.140 , pp. 105-112
    • Szabo, C.1
  • 133
    • 0032499667 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
    • Taddei S, Virdis A, Ghiadoni L, Magagna A, Salvetti A (1998) Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation 97:2222-2229
    • (1998) Circulation , vol.97 , pp. 2222-2229
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5
  • 134
    • 0034897608 scopus 로고    scopus 로고
    • Effect of calcium antagonist or beta blockade treatment on nitric oxide-dependent vasodilation and oxidative stress in essential hypertensive patients
    • Taddei S, Virdis A, Ghiadoni L, Magagna A, Pasini AF, Garbin U, et al (2001) Effect of calcium antagonist or beta blockade treatment on nitric oxide-dependent vasodilation and oxidative stress in essential hypertensive patients. J Hypertens 19:1379-1386
    • (2001) J Hypertens , vol.19 , pp. 1379-1386
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Pasini, A.F.5    Garbin, U.6
  • 136
    • 0348109425 scopus 로고    scopus 로고
    • Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
    • Taniyama Y, Griendling KK (2003) Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42:1075-1081
    • (2003) Hypertension , vol.42 , pp. 1075-1081
    • Taniyama, Y.1    Griendling, K.K.2
  • 137
    • 0036899292 scopus 로고    scopus 로고
    • Angiotensin II and oxidative stress in Dahl salt-sensitive rat with heart failure
    • Tojo A, Onozato ML, Kobayashi N, Goto A, Matsuoka H, Fujita T (2002) Angiotensin II and oxidative stress in Dahl salt-sensitive rat with heart failure. Hypertension 40:834-839
    • (2002) Hypertension , vol.40 , pp. 834-839
    • Tojo, A.1    Onozato, M.L.2    Kobayashi, N.3    Goto, A.4    Matsuoka, H.5    Fujita, T.6
  • 139
    • 0012449739 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway in redox signaling
    • Torres M (2003) Mitogen-activated protein kinase pathway in redox signaling. Front Biosci 8:369-391
    • (2003) Front Biosci , vol.8 , pp. 369-391
    • Torres, M.1
  • 140
    • 0034137152 scopus 로고    scopus 로고
    • Oxidative stress and vascular damage in hypertension
    • Touyz RM (2000) Oxidative stress and vascular damage in hypertension. Curr Hypertens Rep 2:98-105
    • (2000) Curr Hypertens Rep , vol.2 , pp. 98-105
    • Touyz, R.M.1
  • 141
    • 0037335290 scopus 로고    scopus 로고
    • Recent advances in intracellular signalling in hypertension
    • Touyz RM (2003a) Recent advances in intracellular signalling in hypertension. Curr Opin Nephrol Hypertens 12:165-174
    • (2003) Curr Opin Nephrol Hypertens , vol.12 , pp. 165-174
    • Touyz, R.M.1
  • 142
    • 1442274621 scopus 로고    scopus 로고
    • Activated oxygen metabolites: Do they really play a role in angiotensin II-regulated vascular tone?
    • Touyz RM (2003b) Activated oxygen metabolites: do they really play a role in angiotensin II-regulated vascular tone? J Hypertens 21:2235-2238
    • (2003) J Hypertens , vol.21 , pp. 2235-2238
    • Touyz, R.M.1
  • 143
    • 0032737361 scopus 로고    scopus 로고
    • Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells
    • Touyz RM, Schiffrin EL (1999) Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. Hypertension 34:976-982
    • (1999) Hypertension , vol.34 , pp. 976-982
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 144
    • 0033635110 scopus 로고    scopus 로고
    • Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
    • Touyz RM, Schiffrin EL (2000) Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 52:639-672
    • (2000) Pharmacol Rev , vol.52 , pp. 639-672
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 145
    • 0034948793 scopus 로고    scopus 로고
    • Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: Role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways
    • Touyz RM, Schiffrin EL (2001) Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways. J Hypertens 19:1245-1254
    • (2001) J Hypertens , vol.19 , pp. 1245-1254
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 146
    • 0037076798 scopus 로고    scopus 로고
    • Expression of a gp91phox-containing leukocyte-type NADPH oxidase in human vascular smooth muscle cells: Modulation by Ang II
    • Touyz RM, Chen X, He G, Quinn MT, Schiffrin EL (2002a) Expression of a gp91phox-containing leukocyte-type NADPH oxidase in human vascular smooth muscle cells: modulation by Ang II. Circ Res 90:1205-1213
    • (2002) Circ Res , vol.90 , pp. 1205-1213
    • Touyz, R.M.1    Chen, X.2    He, G.3    Quinn, M.T.4    Schiffrin, E.L.5
  • 147
    • 0036179708 scopus 로고    scopus 로고
    • Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats
    • Touyz RM, Wu XH, He G, Salomon S, Schiffrin EL (2002b) Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension 39:479-485
    • (2002) Hypertension , vol.39 , pp. 479-485
    • Touyz, R.M.1    Wu, X.H.2    He, G.3    Salomon, S.4    Schiffrin, E.L.5
  • 148
    • 0037783377 scopus 로고    scopus 로고
    • C-Src induces phosphorylation and translocation of p47phox: Role in superoxide generation by angiotensin II in human vascular smooth muscle cells
    • Touyz RM, Yao G, Schiffrin EL (2003a) c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 23:981-987
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 981-987
    • Touyz, R.M.1    Yao, G.2    Schiffrin, E.L.3
  • 149
    • 0037306526 scopus 로고    scopus 로고
    • Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: Role of receptor tyrosine kinase transactivation
    • Touyz RM, Cruzado M, Tabet F, Yao G, Salomon S, Schiffrin EL (2003b) Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Can J Physiol Pharmacol 81:159-167
    • (2003) Can J Physiol Pharmacol , vol.81 , pp. 159-167
    • Touyz, R.M.1    Cruzado, M.2    Tabet, F.3    Yao, G.4    Salomon, S.5    Schiffrin, E.L.6
  • 150
    • 2642551439 scopus 로고    scopus 로고
    • Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells
    • in press
    • Touyz RM, Yao G, Viel E, Amiri F, Schiffrin EL (2004) Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells. J Hypertens (in press)
    • (2004) J Hypertens
    • Touyz, R.M.1    Yao, G.2    Viel, E.3    Amiri, F.4    Schiffrin, E.L.5
  • 151
    • 0030029311 scopus 로고    scopus 로고
    • Direct in situ measurement of nitric oxide in mesenteric resistance arteries: Increased decomposition by superoxide in hypertension
    • Tschudi M, Mesaros S, Luscher TF, Malinski T (1996) Direct in situ measurement of nitric oxide in mesenteric resistance arteries: increased decomposition by superoxide in hypertension. Hypertension 27:32-35
    • (1996) Hypertension , vol.27 , pp. 32-35
    • Tschudi, M.1    Mesaros, S.2    Luscher, T.F.3    Malinski, T.4
  • 152
    • 0036511547 scopus 로고    scopus 로고
    • Reactive oxygen species and regulation of gene expression
    • Turpaev KT (2002) Reactive oxygen species and regulation of gene expression. Biochemistry 67:281-292
    • (2002) Biochemistry , vol.67 , pp. 281-292
    • Turpaev, K.T.1
  • 153
    • 0032510977 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy
    • Ushio-Fukai M, Alexander RW, Akers M, Griendling KK (1998) p38 mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. Role in vascular smooth muscle cell hypertrophy. J Biol Chem 273:15022-15029
    • (1998) J Biol Chem , vol.273 , pp. 15022-15029
    • Ushio-Fukai, M.1    Alexander, R.W.2    Akers, M.3    Griendling, K.K.4
  • 154
    • 0036790604 scopus 로고    scopus 로고
    • Altered tetrahydrobiopterin metabolism in atherosclerosis: Implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants
    • Vasquez-Vivar J, Duquaine D, Whitsett J, Kalyanaraman B, Rajagopalan S (2002) Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants. Arterioscler Thromb Vasc Biol 22:1655-1661
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1655-1661
    • Vasquez-Vivar, J.1    Duquaine, D.2    Whitsett, J.3    Kalyanaraman, B.4    Rajagopalan, S.5
  • 155
    • 0034090421 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: Involvement of p22phox and reactive oxygen species
    • Viedt C, Soto U, Krieger-Brauer HI, Fei J, Elsing C, Kubler W, Kreuzer J (2000) Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: involvement of p22phox and reactive oxygen species. Arterioscler Thromb Vasc Biol 20:940-948
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 940-948
    • Viedt, C.1    Soto, U.2    Krieger-Brauer, H.I.3    Fei, J.4    Elsing, C.5    Kubler, W.6    Kreuzer, J.7
  • 156
    • 0036710445 scopus 로고    scopus 로고
    • The superoxide-generating NADPH oxidase: Structural aspects and activation mechanism
    • Vignais PV (2002) The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cell Mol Life Sci 59:1428-1459
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1428-1459
    • Vignais, P.V.1
  • 158
    • 0043235659 scopus 로고    scopus 로고
    • Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice
    • Virdis A, Iglarz M, Neves MF, Amiri F, Touyz RM, Rozen R, Schiffrin EL (2003) Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice. Arterioscler Thromb Vasc Biol 23:1352-1357
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1352-1357
    • Virdis, A.1    Iglarz, M.2    Neves, M.F.3    Amiri, F.4    Touyz, R.M.5    Rozen, R.6    Schiffrin, E.L.7
  • 159
    • 1642276271 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
    • Virdis A, Neves MF, Amiri F, Touyz RM, Schiffrin EL (2004) Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens 22:535-542
    • (2004) J Hypertens , vol.22 , pp. 535-542
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Touyz, R.M.4    Schiffrin, E.L.5
  • 160
    • 0037840165 scopus 로고    scopus 로고
    • Use of antioxidant vitamins for the prevention of cardiovascular disease: Meta-analysis of randomised trials
    • Vivekananthan DP, Penn MS, Sapp SK, Hsu A, Topol EJ (2003) Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 361:2017-2023
    • (2003) Lancet , vol.361 , pp. 2017-2023
    • Vivekananthan, D.P.1    Penn, M.S.2    Sapp, S.K.3    Hsu, A.4    Topol, E.J.5
  • 162
    • 0037340081 scopus 로고    scopus 로고
    • Roles of oxidative stress and AT1 receptors in renal hemodynamics and oxygenation in the postclipped 2 K,1C kidney
    • Welch WJ, Mendonca M, Aslam S, Wilcox CS (2003) Roles of oxidative stress and AT1 receptors in renal hemodynamics and oxygenation in the postclipped 2 K,1C kidney. Hypertension 41:692-696
    • (2003) Hypertension , vol.41 , pp. 692-696
    • Welch, W.J.1    Mendonca, M.2    Aslam, S.3    Wilcox, C.S.4
  • 163
    • 0036548475 scopus 로고    scopus 로고
    • Reactive oxygen species: Roles in blood pressure and kidney function
    • Wilcox CS (2002) Reactive oxygen species: roles in blood pressure and kidney function. Curr Hypert Rep 4:160-166
    • (2002) Curr Hypert Rep , vol.4 , pp. 160-166
    • Wilcox, C.S.1
  • 164
    • 0035584538 scopus 로고    scopus 로고
    • Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo
    • Wingler K, Wunsch S, Kreutz R, Rothermund L, Paul M, Schmidt HH (2001) Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. Free Radic Biol Med 31:1456-1464
    • (2001) Free Radic Biol Med , vol.31 , pp. 1456-1464
    • Wingler, K.1    Wunsch, S.2    Kreutz, R.3    Rothermund, L.4    Paul, M.5    Schmidt, H.H.6
  • 165
    • 0035076005 scopus 로고    scopus 로고
    • Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats
    • Wu R, Millette E, Wu L, de Champlain J (2001) Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats. J Hypertens 19:741-748
    • (2001) J Hypertens , vol.19 , pp. 741-748
    • Wu, R.1    Millette, E.2    Wu, L.3    De Champlain, J.4
  • 166
    • 0037154310 scopus 로고    scopus 로고
    • Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats
    • Wu R, Lamontagne D, de Champlain J (2002) Antioxidative properties of acetylsalicylic acid on vascular tissues from normotensive and spontaneously hypertensive rats. Circulation 105:387-392
    • (2002) Circulation , vol.105 , pp. 387-392
    • Wu, R.1    Lamontagne, D.2    De Champlain, J.3
  • 167
    • 0037465511 scopus 로고    scopus 로고
    • Hydrogen peroxide, an endogenous endothelium-derived hyperpolarizing factor, plays an important role in coronary autoregulation in vivo
    • Yada T, Shimokawa H, Hiramatsu O, Kajita T, Shigeto F, Goto M, Ogasawara Y, Kajiya F (2003) Hydrogen peroxide, an endogenous endothelium-derived hyperpolarizing factor, plays an important role in coronary autoregulation in vivo. Circulation 107:1040-1045
    • (2003) Circulation , vol.107 , pp. 1040-1045
    • Yada, T.1    Shimokawa, H.2    Hiramatsu, O.3    Kajita, T.4    Shigeto, F.5    Goto, M.6    Ogasawara, Y.7    Kajiya, F.8
  • 168
    • 0344875019 scopus 로고    scopus 로고
    • Thioredoxin: A key regulator of cardiovascular homeostasis
    • Yamawaki H, Haendeler J, Berk BC (2003) Thioredoxin: a key regulator of cardiovascular homeostasis. Circ Res 93:1029-1033
    • (2003) Circ Res , vol.93 , pp. 1029-1033
    • Yamawaki, H.1    Haendeler, J.2    Berk, B.C.3
  • 171
    • 0034085114 scopus 로고    scopus 로고
    • Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
    • Zalba G, Beaumont FJ, San Jose G, Fortune A, Fortuno MA, Etayo JC, Diez J (2000) Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats. Hypertension 35:1055-1061
    • (2000) Hypertension , vol.35 , pp. 1055-1061
    • Zalba, G.1    Beaumont, F.J.2    San Jose, G.3    Fortune, A.4    Fortuno, M.A.5    Etayo, J.C.6    Diez, J.7
  • 173
    • 0035793313 scopus 로고    scopus 로고
    • Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats
    • Zalba G, San Jose G, Beaumont FJ, Fortuno MA, Fortune A, Diez J (2001b) Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats. Circ Res 88:217-222
    • (2001) Circ Res , vol.88 , pp. 217-222
    • Zalba, G.1    San Jose, G.2    Beaumont, F.J.3    Fortuno, M.A.4    Fortune, A.5    Diez, J.6
  • 174
    • 0037189120 scopus 로고    scopus 로고
    • Mechanisms of action of nitric oxide in the brain stem: Role of oxidative stress
    • Zanzinger J (2002) Mechanisms of action of nitric oxide in the brain stem: role of oxidative stress. Auton Neurosci 98:24-27
    • (2002) Auton Neurosci , vol.98 , pp. 24-27
    • Zanzinger, J.1
  • 175
    • 0347362495 scopus 로고    scopus 로고
    • Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: Reversal by lifelong antioxidant supplementation
    • Zhan CD, Sindhu RK, Vaziri ND (2004) Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: reversal by lifelong antioxidant supplementation. Kidney Int 65:219-227
    • (2004) Kidney Int , vol.65 , pp. 219-227
    • Zhan, C.D.1    Sindhu, R.K.2    Vaziri, N.D.3
  • 176
    • 0041915626 scopus 로고    scopus 로고
    • Gene transfer of human guanosine 5′-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension
    • Zheng JS, Yang XQ, Lookingland KJ, et al (2003) Gene transfer of human guanosine 5′-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension. Circulation 108:1238-1245
    • (2003) Circulation , vol.108 , pp. 1238-1245
    • Zheng, J.S.1    Yang, X.Q.2    Lookingland, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.