Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A2 production

British Journal of Pharmacology

Volumn 134, Issue 8, 2001, Pages 1639-1646

  Gao, Y J ^a   Lee, R M K W ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Hydrogen peroxide; Hypertension; Mesenteric artery; Reactive oxygen species; Spontaneously hypertensive rats; Wistar Kyoto rats

Indexed keywords

6 [2 (2 CHLOROPHENYL) 4 (2 HYDROXYPHENYL) 1,3 DIOXAN 5 YL] 4 HEXENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; DICLOFENAC; FUREGRELATE; HYDROGEN PEROXIDE; INDOMETACIN; MEPACRINE; PHOSPHOLIPASE A2; POTASSIUM CHLORIDE; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2;

ANIMAL TISSUE; AORTA CONSTRICTION; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; HYPERTENSION; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; TACHYPHYLAXIS;

EID: 0035671492     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704420     Document Type: Article

References (45)

1. Differential responses of rat aorta and mesenteric artery to norepinephrine and serotonin in vitro
2. Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat
3. - in vascular smooth muscle cells
4. Vasodilator dysfunction in aged spontaneously hypertensive rats: Changes in NO synthase III and soluble guanylyl cyclase expression, and in superoxide anion production
5. Hydrogen peroxide: An endogenous smooth muscle cell hyperpolarizing factor
6. Chemistry, physiology and pathology of free radicals
7. Signaling mechanisms for the selective vasoconstrictior effect of norbormide on the rat small arteries
8. Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium
9. Role of protein kinase C in oxidant-mediated activation of phospholipase A2 in rabbit pulmonary arterial smooth muscle cells
10. An introduction to free radical biochemistry
11. Oxidation of tartaric acid in the presence of iron
12. Mechanisms of hydrogen peroxide-induced relaxation in rabbit mesenteric small artery
13. Oxidative stress induced by tert-butyl hydroperoxide causes vasoconstriction in the aorta from hypertensive and aged rats: Role of cyclooxygenase-2 isoform
14. Oxidative stress and cardiovascular disease
15. NAD(P)H oxidase: Role in cardiovascular biology and disease
16. Is hydrogen peroxide an EDHF in human radial arteries?
17. Renovascular hypertension, aortic superoxide production: Effect of perindopril and indapamide
18. Peroxide induced activation of glycogen phosphorylase A activity in vascular smooth muscle
19. 2 in aorta of the spontaneously hypertensive rat
20. Lipid hydroperoxides potentiate mesenteric artery vasoconstrictor responses
21. 2+ sensitivity as a mechanism of hydrogen peroxide-induced relaxation of rabbit aorta
22. A comparative study on defense systems for lipid peroxidation by free radicals in spontaneously hypertensive and normotensive rat myocardium
23. 2-induced contraction in pulmonary artery
24. Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery
25. Reactive oxygen species induce apoptosis of vascular smooth muscle cell
26. Free radical tissue damage: Protective role of antioxidant nutrients
27. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice
28. Inactivation of enzymes and oxidative modification of proteins by stimulated neutrophils
29. Hydrogen peroxide and reoxygenation cause prostaglandin-mediated contraction of human placental arteries and veins
30. 20 phosphorylation-independent contraction in intact and permeabilized vascular muscle
31. Free radical generation, lipid peroxidation and essential fatty acids in uncontrolled essential hypertension
32. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
33. Contractile responses elicited by hydrogen peroxide in aorta from normotensive and hypertensive rats. Endothelial modulation and mechanism involved
34. 2+ release from pulmonary smooth muscle mitochondria
35. 2-induced contractions of pulmonary arteries
36. 2
37. 2-induced contraction of rat aorta in the absence of endothelium
38. Vascular superoxide production and vasomotor function in hypertension induced by deoxycorticosterone acetate-salt
39. 2 for platelet-derived growth factor signal transduction
40. In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography
41. Oxidative stress in the Dahl hypertensive rat
42. Peroxides cause dose-dependent relaxant and contractor responses in isolated bovine intrapulmonary arterial and venous rings
43. 2+ and other cellular metabolites
44. Mechanisms of hydrogen peroxide-induced contraction of rat aorta
45. Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta