Endothelin-1 increases vascular superoxide via endothelinA-NADPH oxidase pathway in low-renin hypertension

Circulation

Volumn 107, Issue 7, 2003, Pages 1053-1058

  Li, Lixin ^a   Fink, Gregory D ^a,b   Watts, Stephanie W ^a   Northcott, Carrie A ^a   Galligan, James J ^a,b   Pagano, Patrick J ^c   Chen, Alex F ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c HENRY FORD HOSPITAL   (United States)

Author keywords

Endothelin; Hypertension; NADPH oxidase; Superoxide

Indexed keywords

ALLOPURINOL; ANGIOTENSIN; APOCYNIN; ATRASENTAN; DEOXYCORTICOSTERONE ACETATE; DIPHENYLIODONIUM SALT; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; ENZYME INHIBITOR; FLAVOPROTEIN; MANGANESE SUPEROXIDE DISMUTASE; N(G) NITROARGININE METHYL ESTER; NADPH OXIDASE INHIBITOR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RENIN; SUPEROXIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE INHIBITOR;

ANIMAL CELL; ARTICLE; CAROTID ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME MECHANISM; GENE TRANSFER; HYPERTENSION; INHIBITION KINETICS; MALE; NONHUMAN; OXIDATION KINETICS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING; RENIN RELEASE; SALT INTAKE; SODIUM RETENTION; SYSTOLIC BLOOD PRESSURE; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD PRESSURE; CAROTID ARTERIES; DESOXYCORTICOSTERONE; ENDOTHELIN-1; HYPERTENSION; MALE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; RENIN; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRANSDUCTION, GENETIC; XANTHINE OXIDASE;

EID: 0037465438     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000051459.74466.46     Document Type: Article

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