Endothelial function and oxidative stress in renovascular hypertension

New England Journal of Medicine

Volumn 346, Issue 25, 2002, Pages 1954-1962

  Higashi, Yukihito ^a   Sasaki, Shota ^a   Nakagawa, Keigo ^a   Matsuura, Hideo ^a   Oshima, Tetsuya ^a   Chayama, Kazuaki ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCHOLINE; ISOSORBIDE DINITRATE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; MERCURY; OXYGEN; SILASTIC; VASODILATOR AGENT;

ACETYLCHOLINE RELEASE; ADULT; ANGIOPLASTY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIASTOLIC BLOOD PRESSURE; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; FEMALE; FOREARM BLOOD FLOW; HUMAN; MALE; OXIDATIVE STRESS; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RENAL ARTERY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENOVASCULAR HYPERTENSION; STRAIN GAUGE TRANSDUCER; SYSTOLIC BLOOD PRESSURE; URINARY EXCRETION; VASCULAR RESISTANCE;

ACETYLCHOLINE; ADULT; ANGIOPLASTY; ANGIOTENSIN II; ANTIOXIDANTS; ARTERIOSCLEROSIS; ASCORBIC ACID; BIOLOGICAL MARKERS; BLOOD PRESSURE; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FEMALE; FIBROMUSCULAR DYSPLASIA; FOREARM; HUMANS; HYPERTENSION, RENOVASCULAR; ISOSORBIDE DINITRATE; LIPOPROTEINS; MALE; MATCHED-PAIR ANALYSIS; MIDDLE AGED; OXIDATIVE STRESS; REGIONAL BLOOD FLOW; RENAL ARTERY; VASODILATION; VASODILATOR AGENTS;

EID: 0037142088     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa013591     Document Type: Article

References (28)

1. Increased oxidative stress in experimental renovascular hypertension
2. Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall
3. State-of-the-Art lecture: Role of angiotensin and oxidative stress in essential hypertension
4. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: Contributions to alterations of vasomotor tone
5. Alterations in the vasoreactivity of hypertensive rat aortic rings: Role of nitric oxide and superoxide radicals
6. Vasodilation to acetylcholine in primary and secondary forms of human hypertension
7. Endothelial dysfunction in hypertension is independent from etiology and from vascular structure
8. Endothelial dysfunction in human disease
9. Acute simultaneous stimulation of nitric oxide and oxygen radicals by angiotensin II in humans in vivo
10. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
11. Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
12. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
13. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects - Role of endothelium-derived nitric oxide
14. Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine
15. Oxidative damage to DNA during aging: 8-Hydroxy-2′-deoxyguanosine in rat organ DNA and urine
16. New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus
17. Autoantibody against oxidized LDL and progression of carotid atherosclerosis
18. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduced atherogenesis
19. Presence of autoantibodies against oxidatively modified low-density lipoprotein in essential hypertension: A biochemical signature of an enhanced in vivo low-density lipoprotein oxidation
20. Activation of endothelial L-arginine pathway in resistance arteries: Effect of age and hypertension
21. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension
22. Effect of captopril and enalapril on endothelial function in hypertensive patients
23. Comparison of effects of angiotensin I-converting enzyme inhibition and β-blockade for 2 years on function of small arteries from hypertensive patients
24. Converting enzyme inhibitor improves forearm reactive hyperemia in essential hypertension
25. A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta blockers and diuretic agents on reactive hyperemia in patients with essential hypertension: A multicenter study
26. Effect of angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: Relationship between treatment periods and resistance artery endothelial function
27. Interaction between microvascular alpha 1- and alpha 2-adrenoceptors and endothelium-derived relaxing factor
28. Release of norepinephrine from adrenergic nerve endings of blood vessels is modulated by endothelium-derived relaxing factor