Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species.

Circulation research

Volumn 92, Issue 11, 2003, Pages

  Grote, Karsten ^a   Flach, Inna ^a   Luchtefeld, Maren ^a   Akin, Elvan ^a   Holland, Steven M ^a   Drexler, Helmut ^a   Schieffer, Bernhard ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; GELATINASE; GELATINASE A; MESSENGER RNA; METALLOPROTEINASE; NADPH OXIDASE 1; NEUTROPHIL CYTOSOLIC FACTOR 1; OXIDOREDUCTASE; PHOSPHOPROTEIN; PROGELATINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MECHANICAL STRESS; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELLS, CULTURED; ENZYME PRECURSORS; GELATINASES; GENE EXPRESSION REGULATION; MATRIX METALLOPROTEINASE 2; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; STRESS, MECHANICAL; TRANSCRIPTION, GENETIC; UP-REGULATION;

MLCS; MLOWN;

EID: 0038718531     PISSN: None     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/01.res.0000077044.60138.7c     Document Type: Article

References (0)