A role for reactive oxygen species in endothelial cell anoikis

Circulation Research

Volumn 85, Issue 4, 1999, Pages 304-310

  Li, Arthur E ^a   Ito, Hideaki ^a   Rovira, Ilsa I ^a   Kim, Kyung Soo ^a   Takeda, Kazuyo ^a   Yu, Zu Yi ^a   Ferrans, Victor J ^a   Finkel, Toren ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Caspase; Hydrogen peroxide; JNK; Mitochondria

Indexed keywords

ACETYLCYSTEINE; CASPASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CELL ADHESION; CELL DEATH; CELL LEVEL; CELL SUSPENSION; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033588007     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.85.4.304     Document Type: Article

References (33)

1. Frisch SM, Ruoslahti E. Integrins and anoikis. Curr Opin Cell Biol. 1997; 9:701-706.
2. Coucouvanis E, Martin G. Signals for death and survival: a 2-step mechanism for cavitation in the vertebrate embryo. Cell. 1995;83: 279-287.
3. Boudreau N, Sympson C, Werb Z, Bissell MF. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science. 1995;267:891-893.
4. Meredith JE Jr, Fazeli B, Schwartz MA. The extracellular matrix as a cell survival factor. Mol Biol Cell. 1993;4:953-961.
5. Frisch SM, Vuori K, Ruoslahti E, Chan-Hui PY. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol. 1996;134: 793-799.
6. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell. 1994;79: 1157-1164.
7. Frisch SM, Francis H. Distribution of epithelial cell-matrix interactions induces apoptosis. J Cell Biol. 1994;124:619-626.
8. Frisch SM, Vuori K, Kelaita D, Sicks S. A role for Jun-N-terminal kinase in anoikis: suppression by bcl-2 and crmA. J Cell Biol. 1996;135: 1377-1382.
9. Cardone MH, Salvesen GS, Widmann C, Johnson G, Frisch SM. The regulation of anoikis: MEKK-1 activation requires cleavage. Cell. 1997; 90:315-323.
10. 2-terminal kinase and induction of apoptosis after detachment of epithelial cells. J Cell Biol. 1997;139:1017-1023.
11. Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH, Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 1997;16:2783-2793.
12. Jacobson MD. Reactive oxygen species and programmed cell death. Trends Biochem Sci. 1996;21:83-86.
13. Johnson TM, Yu Z, Ferrans VJ, Lowenstein RA, Finkel T. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc Natl Acad Sci USA. 1996;93:11848-11852.
14. Polyak L, Xia Y, Zweier JL, Kinzle KW, Vogelstein B. A model for p53-induced apoptosis. Nature. 1997;389:300-305.
15. Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H, Tsujimoto Y. Prevention of hypoxia-induced cell death by Bcl-2 and Bel-XL. Nature. 1995;374:811-813.
16. Jacobson MD, Raff MC. Programmed cell death and Bcl-2 protection in very low oxygen. Nature. 1995;374:814-816.
17. Kheradmand F, Werner E, Tremble P, Symons M, Werb Z. Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science. 1998;280:898-902.
18. 2 for platelet-derived growth factor signal transduction. Science. 1995;270:296-299.
19. Cai J, Jones DP. Superoxide in apoptosis: mitochondrial generation triggered by cytochrome c loss. J Biol Chem. 1998;273:11401-11404.
20. Tanaka K, Prayck JB, Takeda K, Yu Z-X, Ferrans VJ, Deshpande SS, Ozaki M, Hwang PM, Lowenstein CJ, Irani K, Finkel T. Expression of Idl results in apoptosis of cardiac myocytes through a redox-dependent mechanism. J Biol Chem. 1998;273:25922-25928.
21. Sulciner D, Irani K, Yu ZY, Ferrans VJ, Goldschmidt-Clermom PJ, Finkel T. rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappa B activation. Mol Cell Biol. 1996; 16:7115-7121.
22. Sundaresan M, Yu ZX, Sulciner DJ, Gutkind JS, Irani K, Goldschmidt-Clermont PJ, Finkel T. Regulation of reactive-oxygen-species generation in fibroblasts by Rac1. Biochem J. 1996;318:379-382.
23. Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ. Mitogenic signaling mediated by oxidants in ras-transformed fibroblasts. Science. 1997;275:1649-1652.
24. Joneson T, Bar-Sagi D. A Rac1 effector site controlling mitogenesis through superoxide production. J Biol Chem. 1998;273:17991-17994.
25. Pena LA, Fuks Z, Kolesnick R. Stress-induced apoptosis and the sphingomyelin pathway. Biochem Pharmacol. 1997;53:615-621.
26. Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science. 1996;274:1855-1859.
27. Nakamura H, Oda T, Hamada K, Hirano T, Shimizu N, Utiyama H. Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells. J Biol Chem. 1998;273:15345-15351.
28. Kaga S, Ragg S, Rogers KA, Ochi A. Activation of p21-CDC42/Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals. J Immunol. 1998;160:4182-4189.
29. Kim BC, Kim JH. Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway. Biochem J. 1998;330:1009-1014.
30. Garcia-Ruiz C, Colell A, Mari M, Morales A, Femandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. J Biol Chem. 1997;272: 11369-11377.
31. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK1). EMBO J. 1998; 9:2596-2606.
32. Gotoh Y, Cooper JA. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-α signal transduction. J Biol Chem. 1998;273:17477-17482.
33. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science. 1997;275:90-94.