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Volumn 43, Issue 1, 2004, Pages 93-98

Sepiapterin Decreases Vasorelaxation in Nitric Oxide Synthase Inhibition-Induced Hypertension

Author keywords

Endothelium; GTP cyclohydrolase 1; Hypertension; Nitric oxide synthase; Tetrahydrobiopterin

Indexed keywords

ACETYLCHOLINE; ASCORBIC ACID; HYDROETHIDINE; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; SEPIAPTERIN; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN;

EID: 0346333139     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200401000-00014     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 0029054512 scopus 로고
    • Nitric oxide and its putative role in hypertension
    • Dominiczak AF, Bohr DF. Nitric oxide and its putative role in hypertension. Hypertension. 1995;25:1202-1211.
    • (1995) Hypertension , vol.25 , pp. 1202-1211
    • Dominiczak, A.F.1    Bohr, D.F.2
  • 2
    • 0028864010 scopus 로고
    • L-NAME hypertension alters endothelial and smooth muscle function in rat aorta: Prevention by trandolapril and verapamil
    • Kung CF, Moreau P, Takase H, et al. L-NAME hypertension alters endothelial and smooth muscle function in rat aorta: prevention by trandolapril and verapamil. Hypertension. 1995;26:744-748.
    • (1995) Hypertension , vol.26 , pp. 744-748
    • Kung, C.F.1    Moreau, P.2    Takase, H.3
  • 3
    • 0029825613 scopus 로고    scopus 로고
    • Elevated blood pressure in mice lacking endothelial nitric oxide synthase
    • Shesely EG, Maeda N, Kim HS, et al. Elevated blood pressure in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci. 1996;93:13176-13181.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 13176-13181
    • Shesely, E.G.1    Maeda, N.2    Kim, H.S.3
  • 4
    • 0035045172 scopus 로고    scopus 로고
    • Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice
    • Cosentino F, Barker JE, Brand MP, et al. Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice. Arterioscler Thromb Vasc Biol. 2001;21:496-502.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 496-502
    • Cosentino, F.1    Barker, J.E.2    Brand, M.P.3
  • 5
    • 0002274895 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: An essential cofactor of nitric oxide synthase with an elusive role
    • Ignarro L, ed. San Diego, CA: Academic Press
    • Gross SS, Jones CL, Hattori Y, et al. Tetrahydrobiopterin: an essential cofactor of nitric oxide synthase with an elusive role. In: Ignarro L, ed. Nitric Oxide Biology and Pathobiology. San Diego, CA: Academic Press, 2000:167-186.
    • (2000) Nitric Oxide Biology and Pathobiology , pp. 167-186
    • Gross, S.S.1    Jones, C.L.2    Hattori, Y.3
  • 6
    • 0032482975 scopus 로고    scopus 로고
    • Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
    • Vasquez-Vivar J, Kalyanaraman B, Martasek P, et al. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci. 1999;95:9220-9225.
    • (1999) Proc Natl Acad Sci , vol.95 , pp. 9220-9225
    • Vasquez-Vivar, J.1    Kalyanaraman, B.2    Martasek, P.3
  • 7
    • 0031577442 scopus 로고    scopus 로고
    • Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase
    • Wever RMF, van Dam T, van Rijn HJM, et al. Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase. Biochem Biophys Res Commun. 1997;237:340-344.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 340-344
    • Wever, R.M.F.1    Van Dam, T.2    Van Rijn, H.J.M.3
  • 8
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A clacium/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, et al. Superoxide generation from endothelial nitric-oxide synthase. A clacium/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem. 1998;273:25804-25808.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3
  • 9
    • 0033566888 scopus 로고    scopus 로고
    • Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes, and heart failure
    • Kojda G, Harrison DG. Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes, and heart failure. Cardiovasc Res. 1999;43:562-571.
    • (1999) Cardiovasc Res , vol.43 , pp. 562-571
    • Kojda, G.1    Harrison, D.G.2
  • 10
    • 0037086565 scopus 로고    scopus 로고
    • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: An EPR spin trapping study
    • Vasquez-Vivar J, Martasek P, Whitsett J, et al. The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. Biochem J. 2002;362:733-739.
    • (2002) Biochem J , vol.362 , pp. 733-739
    • Vasquez-Vivar, J.1    Martasek, P.2    Whitsett, J.3
  • 11
    • 0033512422 scopus 로고    scopus 로고
    • Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2-imbalance in insulin-resistant rat aorta
    • Shinozaki K, Kashiwagi A, Nishio Y, et al. Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2-imbalance in insulin-resistant rat aorta. Diabetes. 1999;48:2437-2445.
    • (1999) Diabetes , vol.48 , pp. 2437-2445
    • Shinozaki, K.1    Kashiwagi, A.2    Nishio, Y.3
  • 13
    • 0028813306 scopus 로고
    • Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
    • Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation. 1995;91:139-144.
    • (1995) Circulation , vol.91 , pp. 139-144
    • Cosentino, F.1    Katusic, Z.S.2
  • 14
    • 33751290467 scopus 로고    scopus 로고
    • Inhibition of tetrahydrobiopterin biosynthesis impairs endothelium-dependent relaxations in canine basilar artery
    • Kinoshita H, Milstein S, Wambi C, et al. Inhibition of tetrahydrobiopterin biosynthesis impairs endothelium-dependent relaxations in canine basilar artery. Am J Physiol. 1997;273:H718-H724.
    • (1997) Am J Physiol , vol.273
    • Kinoshita, H.1    Milstein, S.2    Wambi, C.3
  • 15
    • 0030035889 scopus 로고    scopus 로고
    • Effect of tetrahydrobiopterin on endothelial function in canine middle cerebral arteries
    • Tsutsui M, Milstein S, Katusic ZS. Effect of tetrahydrobiopterin on endothelial function in canine middle cerebral arteries. Circ Res. 1996;79:336-342.
    • (1996) Circ Res , vol.79 , pp. 336-342
    • Tsutsui, M.1    Milstein, S.2    Katusic, Z.S.3
  • 16
    • 0033967254 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease
    • Maier W, Cosentino F, Lutolf RB, et al. Tetrahydrobiopterin improves endothelial function in patients with coronary artery disease. J Cardiovasc Pharmacol. 2000;35:173-178.
    • (2000) J Cardiovasc Pharmacol , vol.35 , pp. 173-178
    • Maier, W.1    Cosentino, F.2    Lutolf, R.B.3
  • 17
    • 0031018510 scopus 로고    scopus 로고
    • Tetrahydrobiopterin restores endothelial function in hypercholesterolemia
    • Stroes E, Kastelein J, Cosentino F, et al. Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest. 1997;99:41-46.
    • (1997) J Clin Invest , vol.99 , pp. 41-46
    • Stroes, E.1    Kastelein, J.2    Cosentino, F.3
  • 18
    • 0034739459 scopus 로고    scopus 로고
    • Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis
    • Tiefenbacher CP, Bleeke T, Vahl C, et al. Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis. Circulation. 2000;102:2172-2179.
    • (2000) Circulation , vol.102 , pp. 2172-2179
    • Tiefenbacher, C.P.1    Bleeke, T.2    Vahl, C.3
  • 19
    • 0035726142 scopus 로고    scopus 로고
    • Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats
    • Hong HJ, Hsiao G, Cheng TH, et al. Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats. Hypertension. 2001;38:1044-1048.
    • (2001) Hypertension , vol.38 , pp. 1044-1048
    • Hong, H.J.1    Hsiao, G.2    Cheng, T.H.3
  • 20
    • 0035887885 scopus 로고    scopus 로고
    • Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical
    • Vasquez-Vivar J, Whitsett J, Martasek P, et al. Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical. Free Radic Biol Med. 2001;31:975-985.
    • (2001) Free Radic Biol Med , vol.31 , pp. 975-985
    • Vasquez-Vivar, J.1    Whitsett, J.2    Martasek, P.3
  • 21
    • 0033547810 scopus 로고    scopus 로고
    • Superoxide production, risk factors, and endothelium-dependent relaxations in human internal mammary arteries
    • Huraux C, Makita T, Kurz S, et al. Superoxide production, risk factors, and endothelium-dependent relaxations in human internal mammary arteries. Circulation. 1999;99:53-59.
    • (1999) Circulation , vol.99 , pp. 53-59
    • Huraux, C.1    Makita, T.2    Kurz, S.3
  • 22
    • 0037219687 scopus 로고    scopus 로고
    • Specific potentiation of endothelium-dependent contractions in SHR by tetrahydrobiopterin
    • Yang D, Levens N, Zhang JN, et al. Specific potentiation of endothelium-dependent contractions in SHR by tetrahydrobiopterin. Hypertension. 2003;41:136-142.
    • (2003) Hypertension , vol.41 , pp. 136-142
    • Yang, D.1    Levens, N.2    Zhang, J.N.3
  • 23
    • 0032211437 scopus 로고    scopus 로고
    • Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical
    • Benov L, Sztejnberg L, Fridovich I. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic Biol Med. 1998;25:826-831.
    • (1998) Free Radic Biol Med , vol.25 , pp. 826-831
    • Benov, L.1    Sztejnberg, L.2    Fridovich, I.3
  • 25
    • 0035120543 scopus 로고    scopus 로고
    • Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells
    • Baker TA, Milstien S, Katusic ZS. Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells. J Cardiovasc Pharmacol. 2001;37:333-338.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 333-338
    • Baker, T.A.1    Milstien, S.2    Katusic, Z.S.3
  • 26
    • 0035808310 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin
    • Heller R, Unbehaun A, Schellenberg B, et al. L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J Biol Chem. 2001;276:40-47.
    • (2001) J Biol Chem , vol.276 , pp. 40-47
    • Heller, R.1    Unbehaun, A.2    Schellenberg, B.3
  • 27
    • 0034625391 scopus 로고    scopus 로고
    • Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin
    • Huang A, Vita JA, Venema RC, et al. Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. J Biol Chem. 2000;275:17399-17406.
    • (2000) J Biol Chem , vol.275 , pp. 17399-17406
    • Huang, A.1    Vita, J.A.2    Venema, R.C.3
  • 28
    • 0142146220 scopus 로고
    • Possible involvement of the cyclic nucleotide system in hypertension
    • Weiss B, ed. Baltimore: University Park Press
    • Amer MS. Possible involvement of the cyclic nucleotide system in hypertension. In: Weiss B, ed. Cyclic Nucletides in Disease. Baltimore: University Park Press, 1975:133-156.
    • (1975) Cyclic Nucletides in Disease , pp. 133-156
    • Amer, M.S.1
  • 29
    • 0037338639 scopus 로고    scopus 로고
    • GTP cyclohydrolase 1 down-regulation contributes to glucocorticoid hypertension in rats
    • Mitchell BM, Dorrance AM, Webb RC. GTP cyclohydrolase 1 down-regulation contributes to glucocorticoid hypertension in rats. Hypertension. 2003;41:669-674.
    • (2003) Hypertension , vol.41 , pp. 669-674
    • Mitchell, B.M.1    Dorrance, A.M.2    Webb, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.