Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids

Circulation

Volumn 101, Issue 2, 2000, Pages 122-124

  Dandona, Paresh ^a   Karne, Rajaram ^a   Ghanim, Husam ^a   Hamouda, Wael ^a   Aljada, Ahmad ^a   Magsino Jr , Cesar H ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Amino acids; Carvedilol; Leukocytes; Oxygen

Indexed keywords

AMINO ACID; CARVEDILOL; PHENYLALANINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TYROSINE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG EFFECT; HEART FAILURE; HUMAN; HUMAN EXPERIMENT; LEUKOCYTE; MONONUCLEAR CELL; NORMAL HUMAN; OXIDATION; PRIORITY JOURNAL; RESPIRATORY BURST;

EID: 0033959248     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.2.122     Document Type: Article

References (17)

1. The TIMI Study Group. The Thrombolysis In Myocardial Infarction (TIMI) trial. N Engl J Med. 1985;31:932-936.
2. The GUSTO Angiographic Investigators. The effects of tissue plasminogen activator, streptokinase, or both on coronary artery patency, ventricular function, and survival after acute myocardial infarction. N Engl J Med. 1993;329:1615-1622.
3. Van de Werf F. Discrepancies between the effects of coronary reperfusion on survival and left ventricular function. Lancet. 1989;1:1367-1369.
4. Vogt A, Von Essen R, Tebbe U, Feuerer W, Appel KF, Neuhaus KL. Impact of early perfusion status of the infarct-related artery on short-term mortality after thrombolysis for acute myocardial infarction: retrospective analysis of four German multicenter studies. J Am Coll Cardiol. 1993; 21:1391-1395.
5. Karagounis L, Sorensen SG, Menlove RI, Moreno F, Anderson JL. Does thrombolysis in myocardial infarction TIMI perfusion grade 2 represent a mostly patent artery or a mostly occluded artery? Enzymatic and electrocardiographic evidence from the TEAM-2 study. J Am Coll Cardiol. 1992;17:1-10.
6. Anderson JL, Karagounis LA, Becker LC, Sorensen SG, Menlove RL, for the TEAM-3 Investigators. TIMI perfusion grade 3 but not grade 2 results in improved outcome after thrombolysis for myocardial infarction: ventriculographic, enzymatic, and electrocardiographic evidence from the TEAM-3 study. Circulation. 1993;87:1829-1839.
7. Gibson CM, Cannon CP, Daley WL, Dodge JT, Alexander B, Marble SJ, McCabe CH, Raymond L, Fortin T, Poole WK, Braunwald E. The TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996;93:879-888.
8. Gibson CM, Murphy SA, Rizzo MJ, Ryan KA, Marble SJ, McCabe CH, Cannon CP, Van de Werf F, Braunwald E. The relationship between the TIMI frame count and clinical outcomes after thrombolytic administration. Circulation. 1999;99:1945-1950.
9. Cannon CP, Gibson CM, McCabe CH, Adgey AAJ, Schweiger MJ, Sequeira RF, Grollier G, Giugliano RP, Frey M, Mueller HS, Steingart RM, Fox NL, Weaver WD, Van de Werf F, Braunwald E, for the TIMI 10B Investigators. TNK-tissue plasminogen activator compared with front-loaded alteplase in acute myocardial infarction: results of the TIMI 10B trial. Circulation,. 1998;98:2805-2814.
10. Gibson CM, Ryan KA, Sparano A, Moynihan JL, Rizzo M, Kelley M, Marble SJ, Laham R, Simons M, McClusky TR, Dodge JT. Angiographic methods to assess human coronary angiogenesis. Am Heart J. 1999;137: 169-179.
11. Stata Corp. Stata Statistical Software: Release 6.0. College Station, Tex: Stata Corp; 1999.
12. Van't Hof AWJ, Liem A, Suryapranata H, Hoorntje JCA, de Boer MJ, Zijlstra F. Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Circulation. 1998;97:2302-2306.
13. Ito H, Tomooka T, Sakai N, Hisahiro Y, Higashino Y, Fujii K, Masuyama T, Kitabatake A, Minamino T. Lack of myocardial perfusion immediately after successful thrombolysis. a predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation. 1992;85: 1699-1705.
14. Kenner MD, Zajac EJ, Kondos GT, Dave R, Winkelmann JW, Joftus J, Laucevicius A, Kybarskis A, Berukstis E, Urbonas A, Feinstein SB. Ability of the no-reflow phenomenon during an acute myocardial infarction to predict left ventricular dysfunction at one-month follow-up. Am J Cardiol. 1995;76:861-868.
15. Sakuma T, Hayashi Y, Sumii K, Imazu M, Yamakido M. Prediction of short- and intermediate-term prognoses of patients with acute myocardial infarction using myocardial contrast echocardiography one day after recanalization. J Am Coll Cardiol. 1998;32:890-897.
16. Marwick TH, Brunken R, Meland N, Brochet E, Baer FM, Binder T, Flachskampf F, Kamp O, Nienaber C, Nihoyannopoulos P, Pierard L, Vanoverschelde JL, van der Wouw P, Lindvall K. Accuracy and feasibility of contrast echocardiography for detection of perfusion defects in routine practice: comparison with wall motion and technetium-99m sestamibi single photon emission computed tomography: the Nycomed NC100100 Investigators. J Am Coll Cardiol. 1998;32:1260-1269.
17. Maes A, Van de Werf F, Nuyts J, Bormans G, Desmet W, Mortelmans L. Impaired myocardial tissue perfusion early after successful thrombolysis: impact on myocardial flow, metabolism, and function at late follow-up. Circulation. 1995;92:2072-2078.