Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Cell

Volumn 177, Issue 6, 2019, Pages 1600-1618.e17

  Sharon, Gil ^a   Cruz, Nikki Jamie ^a   Kang, Dae Wook ^b   Gandal, Michael J ^c,d   Wang, Bo ^a   Kim, Young Mo ^e   Zink, Erika M ^e   Casey, Cameron P ^e   Taylor, Bryn C ^f   Lane, Christianne J ^g   Bramer, Lisa M ^e   Isern, Nancy G ^e   Hoyt, David W ^e   Noecker, Cecilia ^h   Sweredoski, Michael J ^a   Moradian, Annie ^a   Borenstein, Elhanan ^h,i,j,k   Jansson, Janet K ^e   Knight, Rob ^f,l,m,n   Metz, Thomas O ^e   Lois, Carlos ^a   Geschwind, Daniel H ^c,d   Krajmalnik Brown, Rosa ^b,o   Mazmanian, Sarkis K ^a   more..

^a California Institute of Technology   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ University of Washington   (United States)

^j TEL AVIV UNIVERSITY   (Israel)

^k SANTA FE INSTITUTE   (United States)

^l UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^m UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o Arizona State University   (United States)

more..

Author keywords

autism; autism spectrum disorder; bacterial metabolites; gut microbiome; gut brain axis; metabolome; microbiota; mouse model

Indexed keywords

5 AMINOVALERIC ACID; GLUTAMATE DECARBOXYLASE; PROLINE;

ACTINOBACTERIA; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BACTERIUM IDENTIFICATION; BEHAVIOR DISORDER; BRAIN FUNCTION; C57BL 6 MOUSE; CHILD; CLINICAL FEATURE; CLINICAL OUTCOME; COMPULSION; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE SEVERITY; FECES ANALYSIS; FEMALE; FIRMICUTES; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; INTESTINE FLORA; LOCOMOTION; MALE; METABOLOME; MICROBIAL COLONIZATION; MICROBIAL COMMUNITY; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; POPULATION ABUNDANCE; PREDICTIVE VALUE; PREFRONTAL CORTEX; PRIORITY JOURNAL; RNA SEQUENCE; RNA SPLICING; SIGNAL TRANSDUCTION; SOCIAL INTERACTION TEST; ANIMAL; ANIMAL BEHAVIOR; BACTERIUM; BEHAVIOR; BRAIN; DISEASE MODEL; METABOLISM; MICROBIOLOGY; MICROFLORA; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR;

ANIMALS; AUTISM SPECTRUM DISORDER; BACTERIA; BEHAVIOR, ANIMAL; BEHAVIORAL SYMPTOMS; BRAIN; DISEASE MODELS, ANIMAL; GASTROINTESTINAL MICROBIOME; HUMANS; MICE; MICROBIOTA; RISK FACTORS;

EID: 85065864469     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2019.05.004     Document Type: Article

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