Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing

Nature

Volumn 560, Issue 7719, 2018, Pages 441-446

  Parras, Alberto ^a,b   Anta, Héctor ^c,d   Santos Galindo, María ^a,b   Swarup, Vivek ^e   Elorza, Ainara ^a,b   Nieto González, José L ^b,f   Picó, Sara ^a,b   Hernández, Ivó H ^a,b,g   Díaz Hernández, Juan I ^a,b   Belloc, Eulàlia ^d   Rodolosse, Annie ^d   Parikshak, Neelroop N ^e   Peñagarikano, Olga ^e,h,i   Fernández Chacón, Rafael ^b,f   Irimia, Manuel ^j,k   Navarro, Pilar ^c   Geschwind, Daniel H ^e   Méndez, Raúl ^d,l   Lucas, José J ^a,b  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^g UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^h UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

ⁱ CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^j BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Spain)

^k UNIVERSITAT POMPEU FABRA   (Spain)

^l INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN; MESSENGER RNA; TRANSCRIPTOME; CPEB4 PROTEIN, HUMAN; PROTEIN BINDING; RNA BINDING PROTEIN;

BRAIN; CHEMICAL ALTERATION; ENVIRONMENTAL FACTOR; GENE; GENE EXPRESSION; NERVOUS SYSTEM DISORDER; PHENOTYPE; PROTEIN; RISK; RNA; RODENT;

ADENYLATION; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CONTROLLED STUDY; CPEB4 GENE; FEMALE; GENE; GENE EXPRESSION; GENETIC RISK; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RNA SPLICING; ANIMAL; BRAIN; CHEMISTRY; EXON; GENETIC PREDISPOSITION; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; POLYADENYLATION; TRANSGENIC MOUSE;

MUS;

ANIMALS; AUTISM SPECTRUM DISORDER; BRAIN; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MICE; MICE, TRANSGENIC; NEURONS; PHENOTYPE; POLYADENYLATION; PROTEIN BINDING; RNA SPLICING; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSCRIPTOME;

EID: 85052129173     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-018-0423-5     Document Type: Article

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