Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice

Science Translational Medicine

Volumn 9, Issue 401, 2017, Pages

  Selimbeyoglu, Aslihan ^a   Kim, Christina K ^a   Inoue, Masatoshi ^b   Lee, Soo Yeun ^a,b   Hong, Alice S O ^b   Kauvar, Isaac ^b   Ramakrishnan, Charu ^b   Fenno, Lief E ^a,b   Davidson, Thomas J ^a,b   Wright, Matthew ^a   Deisseroth, Karl ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTISM; CNTNAP2 GENE; CONTROLLED STUDY; FEMALE; GENE; GENE INACTIVATION; MALE; MEDIAL PREFRONTAL CORTEX; MOUSE; NERVE CELL INHIBITION; NERVE CELL STIMULATION; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SOCIAL BEHAVIOR; SOCIAL INTERACTION; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DEFICIENCY; GENETIC ENGINEERING; KNOCKOUT MOUSE; METABOLISM; MOVEMENT (PHYSIOLOGY); NERVE CELL; PATHOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX;

CNTNAP2 PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE PROTEIN; OPSIN; PARVALBUMIN;

ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; GENETIC ENGINEERING; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICE, KNOCKOUT; MOVEMENT; NERVE TISSUE PROTEINS; NEURONS; OPSINS; PARVALBUMINS; PREFRONTAL CORTEX; SOCIAL BEHAVIOR;

EID: 85026666748     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aah6733     Document Type: Article

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