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Volumn 89, Issue 1, 2016, Pages 113-128

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; RBFOX1 PROTEIN; RBFOX3 PROTEIN; RNA BINDING PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; ESTRIOL; ESTRIOL SUCCINATE; RBFOX1 PROTEIN, HUMAN; RBFOX1 PROTEIN, MOUSE; RNA SPLICING FACTOR;

EID: 84953835989     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.11.025     Document Type: Article
Times cited : (162)

References (64)
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 58149178561 scopus 로고    scopus 로고
    • AutDB: a gene reference resource for autism research
    • Basu S.N., Kollu R., Banerjee-Basu S. AutDB: a gene reference resource for autism research. Nucleic Acids Res. 2009, 37:D832-D836.
    • (2009) Nucleic Acids Res. , vol.37 , pp. D832-D836
    • Basu, S.N.1    Kollu, R.2    Banerjee-Basu, S.3
  • 4
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - a practical and powerful approach to multiple testing
    • Benjamini Y., Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J. Roy. Stat. Soc. B Met. 1995, 57:289-300.
    • (1995) J. Roy. Stat. Soc. B Met. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 7
    • 80051951015 scopus 로고    scopus 로고
    • The RNA-binding protein Sam68 is a multifunctional player in human cancer
    • Bielli P., Busà R., Paronetto M.P., Sette C. The RNA-binding protein Sam68 is a multifunctional player in human cancer. Endocr. Relat. Cancer 2011, 18:R91-R102.
    • (2011) Endocr. Relat. Cancer , vol.18 , pp. R91-R102
    • Bielli, P.1    Busà, R.2    Paronetto, M.P.3    Sette, C.4
  • 9
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi S.W., Zang J.B., Mele A., Darnell R.B. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009, 460:479-486.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 10
    • 84940234906 scopus 로고    scopus 로고
    • MicroRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer
    • Ciafrè S.A., Galardi S. microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancer. RNA Biol. 2013, 10:935-942.
    • (2013) RNA Biol. , vol.10 , pp. 935-942
    • Ciafrè, S.A.1    Galardi, S.2
  • 11
    • 75149194407 scopus 로고    scopus 로고
    • Autoregulation of Fox protein expression to produce dominant negative splicing factors
    • Damianov A., Black D.L. Autoregulation of Fox protein expression to produce dominant negative splicing factors. RNA 2010, 16:405-416.
    • (2010) RNA , vol.16 , pp. 405-416
    • Damianov, A.1    Black, D.L.2
  • 12
    • 84865645908 scopus 로고    scopus 로고
    • Cytoplasmic RNA-binding proteins and the control of complex brain function
    • Darnell J.C., Richter J.D. Cytoplasmic RNA-binding proteins and the control of complex brain function. Cold Spring Harb. Perspect. Biol. 2012, 4:a012344.
    • (2012) Cold Spring Harb. Perspect. Biol. , vol.4 , pp. a012344
    • Darnell, J.C.1    Richter, J.D.2
  • 16
    • 27944511853 scopus 로고    scopus 로고
    • Splicing-active nuclear extracts from rat brain
    • Grabowski P.J. Splicing-active nuclear extracts from rat brain. Methods 2005, 37:323-330.
    • (2005) Methods , vol.37 , pp. 323-330
    • Grabowski, P.J.1
  • 18
    • 84925767325 scopus 로고    scopus 로고
    • The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity
    • Heraud-Farlow J.E., Kiebler M.A. The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity. Trends Neurosci. 2014, 37:470-479.
    • (2014) Trends Neurosci. , vol.37 , pp. 470-479
    • Heraud-Farlow, J.E.1    Kiebler, M.A.2
  • 21
    • 84866505114 scopus 로고    scopus 로고
    • Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
    • Ince-Dunn G., Okano H.J., Jensen K.B., Park W.Y., Zhong R., Ule J., Mele A., Fak J.J., Yang C., Zhang C., et al. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron 2012, 75:1067-1080.
    • (2012) Neuron , vol.75 , pp. 1067-1080
    • Ince-Dunn, G.1    Okano, H.J.2    Jensen, K.B.3    Park, W.Y.4    Zhong, R.5    Ule, J.6    Mele, A.7    Fak, J.J.8    Yang, C.9    Zhang, C.10
  • 22
    • 84869859046 scopus 로고    scopus 로고
    • Cotranscriptional splicing efficiency differs dramatically between Drosophila and mouse
    • Khodor Y.L., Menet J.S., Tolan M., Rosbash M. Cotranscriptional splicing efficiency differs dramatically between Drosophila and mouse. RNA 2012, 18:2174-2186.
    • (2012) RNA , vol.18 , pp. 2174-2186
    • Khodor, Y.L.1    Menet, J.S.2    Tolan, M.3    Rosbash, M.4
  • 24
    • 70949092754 scopus 로고    scopus 로고
    • Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors
    • Kim K.K., Adelstein R.S., Kawamoto S. Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J. Biol. Chem. 2009, 284:31052-31061.
    • (2009) J. Biol. Chem. , vol.284 , pp. 31052-31061
    • Kim, K.K.1    Adelstein, R.S.2    Kawamoto, S.3
  • 26
    • 70849124572 scopus 로고    scopus 로고
    • Fox-1 family of RNA-binding proteins
    • Kuroyanagi H. Fox-1 family of RNA-binding proteins. Cell. Mol. Life Sci. 2009, 66:3895-3907.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 3895-3907
    • Kuroyanagi, H.1
  • 28
    • 84873407345 scopus 로고    scopus 로고
    • Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy
    • EMINet Consortium, EPICURE ConsortiumEPICURE Consortium
    • Lal D., Trucks H., Møller R.S., Hjalgrim H., Koeleman B.P., de Kovel C.G., Visscher F., Weber Y.G., Lerche H., Becker F., et al. Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy. Epilepsia 2013, 54:265-271. EMINet Consortium, EPICURE ConsortiumEPICURE Consortium.
    • (2013) Epilepsia , vol.54 , pp. 265-271
    • Lal, D.1    Trucks, H.2    Møller, R.S.3    Hjalgrim, H.4    Koeleman, B.P.5    de Kovel, C.G.6    Visscher, F.7    Weber, Y.G.8    Lerche, H.9    Becker, F.10
  • 29
    • 84901913783 scopus 로고    scopus 로고
    • RNA Bind-n-Seq: quantitative assessment of the sequence and structural binding specificity of RNA binding proteins
    • Lambert N., Robertson A., Jangi M., McGeary S., Sharp P.A., Burge C.B. RNA Bind-n-Seq: quantitative assessment of the sequence and structural binding specificity of RNA binding proteins. Mol. Cell 2014, 54:887-900.
    • (2014) Mol. Cell , vol.54 , pp. 887-900
    • Lambert, N.1    Robertson, A.2    Jangi, M.3    McGeary, S.4    Sharp, P.A.5    Burge, C.B.6
  • 30
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B., Trapnell C., Pop M., Salzberg S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009, 10:R25.
    • (2009) Genome Biol. , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 32
    • 70349620615 scopus 로고    scopus 로고
    • An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons
    • Lee J.A., Tang Z.Z., Black D.L. An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons. Genes Dev. 2009, 23:2284-2293.
    • (2009) Genes Dev. , vol.23 , pp. 2284-2293
    • Lee, J.A.1    Tang, Z.Z.2    Black, D.L.3
  • 34
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basis of CaMKII function in synaptic and behavioural memory
    • Lisman J., Schulman H., Cline H. The molecular basis of CaMKII function in synaptic and behavioural memory. Nat. Rev. Neurosci. 2002, 3:175-190.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 37
    • 0018380404 scopus 로고
    • A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells
    • Mackall J., Meredith M., Lane M.D. A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells. Anal. Biochem. 1979, 95:270-274.
    • (1979) Anal. Biochem. , vol.95 , pp. 270-274
    • Mackall, J.1    Meredith, M.2    Lane, M.D.3
  • 40
    • 17544367787 scopus 로고    scopus 로고
    • Tissue-dependent isoforms of mammalian Fox-1 homologs are associated with tissue-specific splicing activities
    • Nakahata S., Kawamoto S. Tissue-dependent isoforms of mammalian Fox-1 homologs are associated with tissue-specific splicing activities. Nucleic Acids Res. 2005, 33:2078-2089.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 2078-2089
    • Nakahata, S.1    Kawamoto, S.2
  • 41
    • 84878044937 scopus 로고    scopus 로고
    • Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression
    • Pandya-Jones A., Bhatt D.M., Lin C.H., Tong A.J., Smale S.T., Black D.L. Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression. RNA 2013, 19:811-827.
    • (2013) RNA , vol.19 , pp. 811-827
    • Pandya-Jones, A.1    Bhatt, D.M.2    Lin, C.H.3    Tong, A.J.4    Smale, S.T.5    Black, D.L.6
  • 42
    • 38149081454 scopus 로고    scopus 로고
    • Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex
    • Papin C., Rouget C., Mandart E. Xenopus Rbm9 is a novel interactor of XGld2 in the cytoplasmic polyadenylation complex. FEBS J. 2008, 275:490-503.
    • (2008) FEBS J. , vol.275 , pp. 490-503
    • Papin, C.1    Rouget, C.2    Mandart, E.3
  • 43
    • 84889561601 scopus 로고    scopus 로고
    • Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
    • Parikshak N.N., Luo R., Zhang A., Won H., Lowe J.K., Chandran V., Horvath S., Geschwind D.H. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell 2013, 155:1008-1021.
    • (2013) Cell , vol.155 , pp. 1008-1021
    • Parikshak, N.N.1    Luo, R.2    Zhang, A.3    Won, H.4    Lowe, J.K.5    Chandran, V.6    Horvath, S.7    Geschwind, D.H.8
  • 47
    • 84867331444 scopus 로고    scopus 로고
    • The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data
    • Smith C.L., Eppig J.T. The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data. Mamm. Genome 2012, 23:653-668.
    • (2012) Mamm. Genome , vol.23 , pp. 653-668
    • Smith, C.L.1    Eppig, J.T.2
  • 48
    • 84863927610 scopus 로고    scopus 로고
    • Functional interplay between RNA-binding protein HuR and microRNAs
    • Srikantan S., Tominaga K., Gorospe M. Functional interplay between RNA-binding protein HuR and microRNAs. Curr. Protein Pept. Sci. 2012, 13:372-379.
    • (2012) Curr. Protein Pept. Sci. , vol.13 , pp. 372-379
    • Srikantan, S.1    Tominaga, K.2    Gorospe, M.3
  • 50
    • 84902129480 scopus 로고    scopus 로고
    • Autism spectrum disorder genetics: diverse genes with diverse clinical outcomes
    • Talkowski M.E., Minikel E.V., Gusella J.F. Autism spectrum disorder genetics: diverse genes with diverse clinical outcomes. Harv. Rev. Psychiatry 2014, 22:65-75.
    • (2014) Harv. Rev. Psychiatry , vol.22 , pp. 65-75
    • Talkowski, M.E.1    Minikel, E.V.2    Gusella, J.F.3
  • 52
    • 84861128352 scopus 로고    scopus 로고
    • An emerging role of RNA-binding proteins as multifunctional regulators of lymphocyte development and function
    • Turner M., Hodson D.J. An emerging role of RNA-binding proteins as multifunctional regulators of lymphocyte development and function. Adv. Immunol. 2012, 115:161-185.
    • (2012) Adv. Immunol. , vol.115 , pp. 161-185
    • Turner, M.1    Hodson, D.J.2
  • 53
    • 27644455141 scopus 로고    scopus 로고
    • Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals
    • Underwood J.G., Boutz P.L., Dougherty J.D., Stoilov P., Black D.L. Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals. Mol. Cell. Biol. 2005, 25:10005-10016.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10005-10016
    • Underwood, J.G.1    Boutz, P.L.2    Dougherty, J.D.3    Stoilov, P.4    Black, D.L.5
  • 54
    • 84903954699 scopus 로고    scopus 로고
    • Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer
    • Vanharanta S., Marney C.B., Shu W., Valiente M., Zou Y., Mele A., Darnell R.B., Massagué J. Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. eLife 2014, 3:3.
    • (2014) eLife , vol.3 , pp. 3
    • Vanharanta, S.1    Marney, C.B.2    Shu, W.3    Valiente, M.4    Zou, Y.5    Mele, A.6    Darnell, R.B.7    Massagué, J.8
  • 57
    • 80054931745 scopus 로고    scopus 로고
    • SpliceTrap: a method to quantify alternative splicing under single cellular conditions
    • Wu J., Akerman M., Sun S., McCombie W.R., Krainer A.R., Zhang M.Q. SpliceTrap: a method to quantify alternative splicing under single cellular conditions. Bioinformatics 2011, 27:3010-3016.
    • (2011) Bioinformatics , vol.27 , pp. 3010-3016
    • Wu, J.1    Akerman, M.2    Sun, S.3    McCombie, W.R.4    Krainer, A.R.5    Zhang, M.Q.6
  • 58
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3[U+02B9] UTRs by comparison of several mammals
    • Xie X., Lu J., Kulbokas E.J., Golub T.R., Mootha V., Lindblad-Toh K., Lander E.S., Kellis M. Systematic discovery of regulatory motifs in human promoters and 3[U+02B9] UTRs by comparison of several mammals. Nature 2005, 434:338-345.
    • (2005) Nature , vol.434 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5    Lindblad-Toh, K.6    Lander, E.S.7    Kellis, M.8
  • 59
    • 72149117411 scopus 로고    scopus 로고
    • Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping
    • Xue Y., Zhou Y., Wu T., Zhu T., Ji X., Kwon Y.S., Zhang C., Yeo G., Black D.L., Sun H., et al. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol. Cell 2009, 36:996-1006.
    • (2009) Mol. Cell , vol.36 , pp. 996-1006
    • Xue, Y.1    Zhou, Y.2    Wu, T.3    Zhu, T.4    Ji, X.5    Kwon, Y.S.6    Zhang, C.7    Yeo, G.8    Black, D.L.9    Sun, H.10
  • 60
    • 84872601985 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits
    • Xue Y., Ouyang K., Huang J., Zhou Y., Ouyang H., Li H., Wang G., Wu Q., Wei C., Bi Y., et al. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell 2013, 152:82-96.
    • (2013) Cell , vol.152 , pp. 82-96
    • Xue, Y.1    Ouyang, K.2    Huang, J.3    Zhou, Y.4    Ouyang, H.5    Li, H.6    Wang, G.7    Wu, Q.8    Wei, C.9    Bi, Y.10
  • 61
    • 59649107040 scopus 로고    scopus 로고
    • An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
    • Yeo G.W., Coufal N.G., Liang T.Y., Peng G.E., Fu X.D., Gage F.H. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat. Struct. Mol. Biol. 2009, 16:130-137.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 130-137
    • Yeo, G.W.1    Coufal, N.G.2    Liang, T.Y.3    Peng, G.E.4    Fu, X.D.5    Gage, F.H.6
  • 62
    • 84904572509 scopus 로고    scopus 로고
    • Direct binding of Ataxin-2 to distinct elements in 3[U+02B9] UTRs promotes mRNA stability and protein expression
    • Yokoshi M., Li Q., Yamamoto M., Okada H., Suzuki Y., Kawahara Y. Direct binding of Ataxin-2 to distinct elements in 3[U+02B9] UTRs promotes mRNA stability and protein expression. Mol. Cell 2014, 55:186-198.
    • (2014) Mol. Cell , vol.55 , pp. 186-198
    • Yokoshi, M.1    Li, Q.2    Yamamoto, M.3    Okada, H.4    Suzuki, Y.5    Kawahara, Y.6
  • 64
    • 51949111100 scopus 로고    scopus 로고
    • Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2
    • Zhang C., Zhang Z., Castle J., Sun S., Johnson J., Krainer A.R., Zhang M.Q. Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev. 2008, 22:2550-2563.
    • (2008) Genes Dev. , vol.22 , pp. 2550-2563
    • Zhang, C.1    Zhang, Z.2    Castle, J.3    Sun, S.4    Johnson, J.5    Krainer, A.R.6    Zhang, M.Q.7


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