A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-L-proline

Science

Volumn 355, Issue 6325, 2017, Pages

  Levin, B J ^a   Huang, Y Y ^a   Peck, S C ^a   Wei, Y ^b   Martinez Del Campo A ^a   Marks, J A ^a   Franzosa, E A ^c,d   Huttenhower, C ^c,d   Balskus, E P ^a,d  

^a HARVARD UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCYL RADICAL ENZYME; HYDROLYASE; HYDROXYPROLINE; MICROBIAL ENZYME; UNCLASSIFIED DRUG; PROLINE DEHYDROGENASE; PROPANEDIOL DEHYDRATASE;

AMINO ACID; DIGESTIVE SYSTEM; ENZYME; INFORMATION MANAGEMENT; MICROBIAL COMMUNITY; MICROBIOLOGY; RADICAL;

AMINO ACID METABOLISM; AMINO ACID SEQUENCE; ARTICLE; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; INTESTINE FLORA; LOWER GASTROINTESTINAL TRACT; METAGENOME; METAGENOMICS; MICROBIAL COMMUNITY; NONHUMAN; PATHOGENESIS; PLASMID; PRIORITY JOURNAL; PROTEIN PROCESSING; SEQUENCE ALIGNMENT; WORKFLOW; ANAEROBIC GROWTH; CHEMISTRY; GASTROINTESTINAL TRACT; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; PROTEIN MOTIF;

AMINO ACID MOTIFS; ANAEROBIOSIS; GASTROINTESTINAL MICROBIOME; GASTROINTESTINAL TRACT; HUMANS; HYDROXYPROLINE; METAGENOME; PROLINE OXIDASE; PROPANEDIOL DEHYDRATASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE ALIGNMENT;

EID: 85012066508     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aai8386     Document Type: Article

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