Taurine inhibits K +-Cl - cotransporter KCC2 to regulate embryonic Cl - homeostasis via with-no-lysine (WNK) protein kinase signaling pathway

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 20839-20850

  Inoue, Koichi ^a   Furukawa, Tomonori ^a   Kumada, Tatsuro ^a   Yamada, Junko ^b   Wang, Tianying ^a   Inoue, Rieko ^a   Fukuda, Atsuo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DEVELOPMENT; CEREBRAL CORTEX; IN-VITRO; IN-VIVO; INHIBITORY EFFECT; OVER-EXPRESSION; PROTEIN KINASE; RADIAL MIGRATION; SIGNALING PATHWAYS; STRESS RESPONSE;

ENZYMES; PHOSPHORYLATION; PHYSIOLOGY;

AMINO ACIDS;

4 AMINOBUTYRIC ACID; OXIDATIVE STRESS RESPONSE 1 PROTEIN; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER 2; PROTEIN KINASE; PROTEIN KINASE WNK1; STE20 SPS1 RELATED PROLINE ALANINE RICH KINASE; TAURINE; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CHLORIDE HOMEOSTASIS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CEREBRAL CORTEX; EMBRYO, MAMMALIAN; HOMEOSTASIS; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SYMPORTERS; TAURINE;

EID: 84862275080     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.319418     Document Type: Article

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