Application of LC-MS/MS analysis of plasma amino acids profiles in children with autism

Journal of Clinical Biochemistry and Nutrition

Volumn 51, Issue 3, 2012, Pages 248-249

  Tu, Wen Jun ^a   Chen, Hui ^a   He, Jian ^b  

^a CHINA REHABILITATION RESEARCH CENTER   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Amino acids profiles; Autism; Chinese; Liquid chromatography tandem mass spectrometry

Indexed keywords

ADRENALIN; AMINO ACID; DOPAMINE; GLUTAMIC ACID; GLUTAMINE; HOMOCYSTEINE; LEUCINE; LYSINE; NORADRENALIN; TAURINE; TRYPTOPHAN; TYROSINE; VALINE;

AMINO ACID ANALYSIS; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; AUTISM; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; HOSPITALIZATION; HUMAN; LENGTH OF STAY; LETTER; LIQUID CHROMATOGRAPHY; PATHOPHYSIOLOGY; PRESCHOOL CHILD; PROSPECTIVE STUDY; TANDEM MASS SPECTROMETRY;

EID: 84868605782     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.12-45     Document Type: Letter

References (6)

1. Eigsti IM, Shapiro T. A systems neuroscience approach to autism: biological, cognitive, and clinical perspectives. Ment Retard Dev Disabil Res Rev 2003; 9: 205-215.
2. Taylor B, Miller E, Farrington CP, et al. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet 1999; 353: 2026-2029.
3. Arnold GL, Hyman SL, Mooney RA, Kirby RS. Plasma amino acids profiles in children with autism: potential risk of nutritional deficiencies. J Autism Dev Disord 2003; 33: 449-454.
4. Leblond CS, Heinrich J, Delorme R, et al. Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet 2012; 8: e1002521.
5. Xia W, Zhou Y, Sun C, Wang J, Wu L. A preliminary study on nutritional status and intake in Chinese children with autism. Eur J Pediatr 2010; 169: 1201-1206.
6. Whiteley P, Haracopos D, Knivsberg AM, et al. The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders. Nutr Neurosci 2010; 13: 87-100.