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Volumn 11, Issue 1, 2019, Pages

Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease

Author keywords

Cardiovascular disease; ECs; NADPH oxidases; Polyphenols; ROS; Senescence; VSMCS

Indexed keywords

ANTHOCYANIDIN; ASCORBIC ACID; CATECHIN; CHOLESTEROL; EPICATECHIN; EXTRA VIRGIN OLIVE OIL; FLAVONOID; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; P47PHOX; P67PHOX; POLYPHENOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 85059267692     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu11010053     Document Type: Review
Times cited : (188)

References (133)
  • 1
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: When bad things happen to good cells
    • Campisi, J.; d’Adda di Fagagna, F. Cellular senescence: When bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 2007, 8, 729–740. [CrossRef] [PubMed]
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 729-740
    • Campisi, J.1    D’Adda Di Fagagna, F.2
  • 3
    • 0028582034 scopus 로고
    • Growth suppression by p18, a p16INK4/MTS1-and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan, K.L.; Jenkins, C.W.; Li, Y.; Nichols, M.A.; Wu, X.; O’Keefe, C.L.; Matera, A.G.; Xiong, Y. Growth suppression by p18, a p16INK4/MTS1-and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev. 1994, 8, 2939–2952. [CrossRef] [PubMed]
    • (1994) Genes Dev , vol.8 , pp. 2939-2952
    • Guan, K.L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.A.4    Wu, X.5    O’Keefe, C.L.6    Matera, A.G.7    Xiong, Y.8
  • 6
    • 33749020871 scopus 로고    scopus 로고
    • P53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts
    • Jackson, J.G.; Pereira-Smith, O.M. p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts. Cancer Res. 2006, 66, 8356–8360. [CrossRef] [PubMed]
    • (2006) Cancer Res , vol.66 , pp. 8356-8360
    • Jackson, J.G.1    Pereira-Smith, O.M.2
  • 7
    • 33747625689 scopus 로고    scopus 로고
    • Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress
    • Matthews, C.; Gorenne, I.; Scott, S.; Figg, N.; Kirkpatrick, P.; Ritchie, A.; Goddard, M.; Bennett, M. Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress. Circ. Res. 2006, 99, 156–164. [CrossRef] [PubMed]
    • (2006) Circ. Res. , vol.99 , pp. 156-164
    • Matthews, C.1    Gorenne, I.2    Scott, S.3    Figg, N.4    Kirkpatrick, P.5    Ritchie, A.6    Goddard, M.7    Bennett, M.8
  • 8
    • 0035325264 scopus 로고    scopus 로고
    • Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts
    • Chen, Q.M.; Prowse, K.R.; Tu, V.C.; Purdom, S.; Linskens, M.H. Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp. Cell Res. 2001, 265, 294–303. [CrossRef]
    • (2001) Exp. Cell Res. , vol.265 , pp. 294-303
    • Chen, Q.M.1    Prowse, K.R.2    Tu, V.C.3    Purdom, S.4    Linskens, M.H.5
  • 9
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • Campisi, J. Aging, cellular senescence, and cancer. Annu. Rev. Physiol. 2013, 75, 685–705. [CrossRef]
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 685-705
    • Campisi, J.1
  • 10
    • 85054025424 scopus 로고    scopus 로고
    • Cellular Senescence: The Sought or the Unwanted?
    • Sun, Y.; Coppe, J.P.; Lam, E.W. Cellular Senescence: The Sought or the Unwanted? Trends Mol. Med. 2018, 24, 871–885. [CrossRef]
    • (2018) Trends Mol. Med. , vol.24 , pp. 871-885
    • Sun, Y.1    Coppe, J.P.2    Lam, E.W.3
  • 11
    • 77952105389 scopus 로고    scopus 로고
    • Inflammatory networks during cellular senescence: Causes and consequences
    • Freund, A.; Orjalo, A.V.; Desprez, P.Y.; Campisi, J. Inflammatory networks during cellular senescence: Causes and consequences. Trends Mol. Med. 2010, 16, 238–246. [CrossRef] [PubMed]
    • (2010) Trends Mol. Med. , vol.16 , pp. 238-246
    • Freund, A.1    Orjalo, A.V.2    Desprez, P.Y.3    Campisi, J.4
  • 12
    • 84940391650 scopus 로고    scopus 로고
    • Senescent Vascular Smooth Muscle Cells Drive Inflammation through an Interleukin-1alpha-Dependent Senescence-Associated Secretory Phenotype
    • Gardner, S.E.; Humphry, M.; Bennett, M.R.; Clarke, M.C. Senescent Vascular Smooth Muscle Cells Drive Inflammation through an Interleukin-1alpha-Dependent Senescence-Associated Secretory Phenotype. Arterioscler. Thromb. Vasc. Biol. 2015, 35, 1963–1974. [CrossRef] [PubMed]
    • (2015) Arterioscler. Thromb. Vasc. Biol. , vol.35 , pp. 1963-1974
    • Gardner, S.E.1    Humphry, M.2    Bennett, M.R.3    Clarke, M.C.4
  • 14
    • 79955017452 scopus 로고    scopus 로고
    • P38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
    • Freund, A.; Patil, C.K.; Campisi, J. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J. 2011, 30, 1536–1548. [CrossRef] [PubMed]
    • (2011) EMBO J , vol.30 , pp. 1536-1548
    • Freund, A.1    Patil, C.K.2    Campisi, J.3
  • 15
    • 54349125514 scopus 로고    scopus 로고
    • 4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-kappaB signaling pathways
    • Lee, S.J.; Seo, K.W.; Yun, M.R.; Bae, S.S.; Lee, W.S.; Hong, K.W.; Kim, C.D. 4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-kappaB signaling pathways. Free Radic. Biol. Med. 2008, 45, 1487–1492. [CrossRef] [PubMed]
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 1487-1492
    • Lee, S.J.1    Seo, K.W.2    Yun, M.R.3    Bae, S.S.4    Lee, W.S.5    Hong, K.W.6    Kim, C.D.7
  • 16
    • 85016779291 scopus 로고    scopus 로고
    • Zinc regulates Nox1 expression through a NF-kappaB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells
    • Salazar, G.; Huang, J.; Feresin, R.G.; Zhao, Y.; Griendling, K.K. Zinc regulates Nox1 expression through a NF-kappaB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells. Free Radic. Biol. Med. 2017, 108, 225–235. [CrossRef] [PubMed]
    • (2017) Free Radic. Biol. Med. , vol.108 , pp. 225-235
    • Salazar, G.1    Huang, J.2    Feresin, R.G.3    Zhao, Y.4    Griendling, K.K.5
  • 17
    • 84891713034 scopus 로고    scopus 로고
    • Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
    • Coppe, J.P.; Patil, C.K.; Rodier, F.; Sun, Y.; Munoz, D.P.; Goldstein, J.; Nelson, P.S.; Desprez, P.Y.; Campisi, J. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 2008, 6, 2853–2868. [CrossRef] [PubMed]
    • (2008) Plos Biol , vol.6 , pp. 2853-2868
    • Coppe, J.P.1    Patil, C.K.2    Rodier, F.3    Sun, Y.4    Munoz, D.P.5    Goldstein, J.6    Nelson, P.S.7    Desprez, P.Y.8    Campisi, J.9
  • 18
    • 80054682555 scopus 로고    scopus 로고
    • Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype
    • Coppe, J.P.; Rodier, F.; Patil, C.K.; Freund, A.; Desprez, P.Y.; Campisi, J. Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. J. Biol. Chem. 2011, 286, 36396–36403. [CrossRef] [PubMed]
    • (2011) J. Biol. Chem. , vol.286 , pp. 36396-36403
    • Coppe, J.P.1    Rodier, F.2    Patil, C.K.3    Freund, A.4    Desprez, P.Y.5    Campisi, J.6
  • 21
    • 0242361641 scopus 로고    scopus 로고
    • Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis
    • Minamino, T.; Yoshida, T.; Tateno, K.; Miyauchi, H.; Zou, Y.; Toko, H.; Komuro, I. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003, 108, 2264–2269. [CrossRef] [PubMed]
    • (2003) Circulation , vol.108 , pp. 2264-2269
    • Minamino, T.1    Yoshida, T.2    Tateno, K.3    Miyauchi, H.4    Zou, Y.5    Toko, H.6    Komuro, I.7
  • 23
    • 4744347593 scopus 로고    scopus 로고
    • Replication protein A and gamma-H2AX foci assembly is triggered by cellular response to DNA double-strand breaks
    • Balajee, A.S.; Geard, C.R. Replication protein A and gamma-H2AX foci assembly is triggered by cellular response to DNA double-strand breaks. Exp. Cell Res. 2004, 300, 320–334. [CrossRef] [PubMed]
    • (2004) Exp. Cell Res. , vol.300 , pp. 320-334
    • Balajee, A.S.1    Geard, C.R.2
  • 24
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • Bedard, K.; Krause, K.H. The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol. Rev. 2007, 87, 245–313. [CrossRef] [PubMed]
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 25
    • 0042810670 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidases: Specific features, expression, and regulation
    • Lassegue, B.; Clempus, R.E. Vascular NAD(P)H oxidases: Specific features, expression, and regulation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 285, R277–R297. [CrossRef] [PubMed]
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.285 , pp. R277-R297
    • Lassegue, B.1    Clempus, R.E.2
  • 26
    • 85008352122 scopus 로고    scopus 로고
    • Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases
    • Kigawa, Y.; Miyazaki, T.; Lei, X.F.; Kim-Kaneyama, J.R.; Miyazaki, A. Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases. J. Atheroscler. Thromb. 2017, 24, 1–13. [CrossRef] [PubMed]
    • (2017) J. Atheroscler. Thromb , vol.24 , pp. 1-13
    • Kigawa, Y.1    Miyazaki, T.2    Lei, X.F.3    Kim-Kaneyama, J.R.4    Miyazaki, A.5
  • 27
    • 85046139347 scopus 로고    scopus 로고
    • NADPH Oxidases and Mitochondria in Vascular Senescence
    • Salazar, G. NADPH Oxidases and Mitochondria in Vascular Senescence. Int. J. Mol. Sci. 2018, 19, 1327. [CrossRef] [PubMed]
    • (2018) Int. J. Mol. Sci. , vol.19 , pp. 1327
    • Salazar, G.1
  • 28
    • 27444447834 scopus 로고    scopus 로고
    • Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice
    • Dikalova, A.; Clempus, R.; Lassegue, B.; Cheng, G.; McCoy, J.; Dikalov, S.; San Martin, A.; Lyle, A.; Weber, D.S.; Weiss, D.; et al. Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Circulation 2005, 112, 2668–2676. [CrossRef] [PubMed]
    • (2005) Circulation , vol.112 , pp. 2668-2676
    • Dikalova, A.1    Clempus, R.2    Lassegue, B.3    Cheng, G.4    McCoy, J.5    Dikalov, S.6    San Martin, A.7    Lyle, A.8    Weber, D.S.9    Weiss, D.10
  • 29
    • 84991480380 scopus 로고    scopus 로고
    • Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells
    • Feresin, R.G.; Huang, J.; Klarich, D.S.; Zhao, Y.; Pourafshar, S.; Arjmandi, B.H.; Salazar, G. Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells. Food Funct. 2016, 7, 4175–4187. [CrossRef]
    • (2016) Food Funct , vol.7 , pp. 4175-4187
    • Feresin, R.G.1    Huang, J.2    Klarich, D.S.3    Zhao, Y.4    Pourafshar, S.5    Arjmandi, B.H.6    Salazar, G.7
  • 30
    • 80053906943 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells
    • Maheswaranathan, M.; Gole, H.K.; Fernandez, I.; Lassegue, B.; Griendling, K.K.; San Martin, A. Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. J. Biol. Chem. 2011, 286, 35430–35437. [CrossRef]
    • (2011) J. Biol. Chem. , vol.286 , pp. 35430-35437
    • Maheswaranathan, M.1    Gole, H.K.2    Fernandez, I.3    Lassegue, B.4    Griendling, K.K.5    San Martin, A.6
  • 31
    • 85017350229 scopus 로고    scopus 로고
    • Microvascular NADPH oxidase in health and disease
    • Li, Y.; Pagano, P.J. Microvascular NADPH oxidase in health and disease. Free Radic. Biol. Med. 2017, 109, 33–47. [CrossRef] [PubMed]
    • (2017) Free Radic. Biol. Med , vol.109 , pp. 33-47
    • Li, Y.1    Pagano, P.J.2
  • 32
    • 77954202847 scopus 로고    scopus 로고
    • Pro-inflammatory effects of interleukin-17A on vascular smooth muscle cells involve NAD(P)H-oxidase derived reactive oxygen species
    • Pietrowski, E.; Bender, B.; Huppert, J.; White, R.; Luhmann, H.J.; Kuhlmann, C.R. Pro-inflammatory effects of interleukin-17A on vascular smooth muscle cells involve NAD(P)H-oxidase derived reactive oxygen species. J. Vasc. Res. 2011, 48, 52–58. [CrossRef] [PubMed]
    • (2011) J. Vasc. Res. , vol.48 , pp. 52-58
    • Pietrowski, E.1    Bender, B.2    Huppert, J.3    White, R.4    Luhmann, H.J.5    Kuhlmann, C.R.6
  • 33
    • 84943338778 scopus 로고    scopus 로고
    • INF-gamma Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself
    • Ellison, M.A.; Thurman, G.; Gearheart, C.M.; Seewald, R.H.; Porter, C.C.; Ambruso, D.R. INF-gamma Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself. PLoS ONE 2015, 10, e0136766. [CrossRef] [PubMed]
    • (2015) Plos ONE , vol.10
    • Ellison, M.A.1    Thurman, G.2    Gearheart, C.M.3    Seewald, R.H.4    Porter, C.C.5    Ambruso, D.R.6
  • 34
    • 65349125859 scopus 로고    scopus 로고
    • Identification of structural elements in Nox1 and Nox4 controlling localization and activity
    • Helmcke, I.; Heumuller, S.; Tikkanen, R.; Schroder, K.; Brandes, R.P. Identification of structural elements in Nox1 and Nox4 controlling localization and activity. Antioxid. Redox Signal. 2009, 11, 1279–1287. [CrossRef] [PubMed]
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 1279-1287
    • Helmcke, I.1    Heumuller, S.2    Tikkanen, R.3    Schroder, K.4    Brandes, R.P.5
  • 35
    • 20744440943 scopus 로고    scopus 로고
    • The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: Its regulation by oxidase organizers and activators
    • Ueno, N.; Takeya, R.; Miyano, K.; Kikuchi, H.; Sumimoto, H. The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: Its regulation by oxidase organizers and activators. J. Biol. Chem. 2005, 280, 23328–23339. [CrossRef] [PubMed]
    • (2005) J. Biol. Chem. , vol.280 , pp. 23328-23339
    • Ueno, N.1    Takeya, R.2    Miyano, K.3    Kikuchi, H.4    Sumimoto, H.5
  • 37
    • 77957360252 scopus 로고    scopus 로고
    • Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1)
    • Flaherty, J.P.; Spruce, C.A.; Fairfield, H.E.; Bergstrom, D.E. Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1). Genesis 2010, 48, 568–575. [CrossRef]
    • (2010) Genesis , vol.48 , pp. 568-575
    • Flaherty, J.P.1    Spruce, C.A.2    Fairfield, H.E.3    Bergstrom, D.E.4
  • 38
    • 76749124314 scopus 로고    scopus 로고
    • NOX3-derived reactive oxygen species promote TNF-alpha-induced reductions in hepatocyte glycogen levels via a JNK pathway
    • Li, L.; He, Q.; Huang, X.; Man, Y.; Zhou, Y.; Wang, S.; Wang, J.; Li, J. NOX3-derived reactive oxygen species promote TNF-alpha-induced reductions in hepatocyte glycogen levels via a JNK pathway. FEBS Lett. 2010, 584, 995–1000. [CrossRef]
    • (2010) FEBS Lett , vol.584 , pp. 995-1000
    • Li, L.1    He, Q.2    Huang, X.3    Man, Y.4    Zhou, Y.5    Wang, S.6    Wang, J.7    Li, J.8
  • 41
    • 33646716659 scopus 로고    scopus 로고
    • The mechanism of superoxide production by NADH:Ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
    • Kussmaul, L.; Hirst, J. The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc. Natl. Acad. Sci. USA 2006, 103, 7607–7612. [CrossRef] [PubMed]
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7607-7612
    • Kussmaul, L.1    Hirst, J.2
  • 43
    • 77953476933 scopus 로고    scopus 로고
    • Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells
    • Manea, A.; Tanase, L.I.; Raicu, M.; Simionescu, M. Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. Biochem. Biophys. Res. Commun. 2010, 396, 901–907. [CrossRef] [PubMed]
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 901-907
    • Manea, A.1    Tanase, L.I.2    Raicu, M.3    Simionescu, M.4
  • 45
    • 84940786859 scopus 로고    scopus 로고
    • PGC-1alpha Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases
    • Xiong, S.; Patrushev, N.; Forouzandeh, F.; Hilenski, L.; Alexander, R.W. PGC-1alpha Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases. Cell Rep. 2015, 12, 1391–1399. [CrossRef] [PubMed]
    • (2015) Cell Rep , vol.12 , pp. 1391-1399
    • Xiong, S.1    Patrushev, N.2    Forouzandeh, F.3    Hilenski, L.4    Alexander, R.W.5
  • 46
    • 19444365211 scopus 로고    scopus 로고
    • PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
    • Valle, I.; Alvarez-Barrientos, A.; Arza, E.; Lamas, S.; Monsalve, M. PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc. Res. 2005, 66, 562–573. [CrossRef] [PubMed]
    • (2005) Cardiovasc. Res. , vol.66 , pp. 562-573
    • Valle, I.1    Alvarez-Barrientos, A.2    Arza, E.3    Lamas, S.4    Monsalve, M.5
  • 48
    • 84876283524 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1alpha is a central negative regulator of vascular senescence
    • Xiong, S.; Salazar, G.; Patrushev, N.; Ma, M.; Forouzandeh, F.; Hilenski, L.; Alexander, R.W. Peroxisome proliferator-activated receptor gamma coactivator-1alpha is a central negative regulator of vascular senescence. Arterioscler. Thromb. Vasc. Biol. 2013, 33, 988–998. [CrossRef]
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 988-998
    • Xiong, S.1    Salazar, G.2    Patrushev, N.3    Ma, M.4    Forouzandeh, F.5    Hilenski, L.6    Alexander, R.W.7
  • 49
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: Chemistry, bioavailability and effects on health
    • Crozier, A.; Jaganath, I.B.; Clifford, M.N. Dietary phenolics: Chemistry, bioavailability and effects on health. Nat. Prod. Rep. 2009, 26, 1001–1043. [CrossRef]
    • (2009) Nat. Prod. Rep. , vol.26 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 51
    • 84879798489 scopus 로고    scopus 로고
    • Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro
    • Johnson, M.H.; de Mejia, E.G.; Fan, J.; Lila, M.A.; Yousef, G.G. Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro. Mol. Nutr. Food Res. 2013, 57, 1182–1197. [CrossRef] [PubMed]
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1182-1197
    • Johnson, M.H.1    de Mejia, E.G.2    Fan, J.3    Lila, M.A.4    Yousef, G.G.5
  • 53
    • 84903765330 scopus 로고    scopus 로고
    • Dietary grape powder increases IL-1beta and IL-6 production by lipopolysaccharide-activated monocytes and reduces plasma concentrations of large LDL and large LDL-cholesterol particles in obese humans
    • Zunino, S.J.; Peerson, J.M.; Freytag, T.L.; Breksa, A.P.; Bonnel, E.L.; Woodhouse, L.R.; Storms, D.H. Dietary grape powder increases IL-1beta and IL-6 production by lipopolysaccharide-activated monocytes and reduces plasma concentrations of large LDL and large LDL-cholesterol particles in obese humans. Br. J. Nutr. 2014, 112, 369–380. [CrossRef] [PubMed]
    • (2014) Br. J. Nutr. , vol.112 , pp. 369-380
    • Zunino, S.J.1    Peerson, J.M.2    Freytag, T.L.3    Breksa, A.P.4    Bonnel, E.L.5    Woodhouse, L.R.6    Storms, D.H.7
  • 54
    • 84937603863 scopus 로고    scopus 로고
    • Mixed pro-and anti-oxidative effects of pomegranate polyphenols in cultured cells
    • Danesi, F.; Kroon, P.A.; Saha, S.; de Biase, D.; D’Antuono, L.F.; Bordoni, A. Mixed pro-and anti-oxidative effects of pomegranate polyphenols in cultured cells. Int. J. Mol. Sci. 2014, 15, 19458–19471. [CrossRef] [PubMed]
    • (2014) Int. J. Mol. Sci. , vol.15 , pp. 19458-19471
    • Danesi, F.1    Kroon, P.A.2    Saha, S.3    de Biase, D.4    D’Antuono, L.F.5    Bordoni, A.6
  • 55
    • 84929152744 scopus 로고    scopus 로고
    • Anti-atherogenic properties of date vs. Pomegranate polyphenols: The benefits of the combination
    • Rosenblat, M.; Volkova, N.; Borochov-Neori, H.; Judeinstein, S.; Aviram, M. Anti-atherogenic properties of date vs. pomegranate polyphenols: The benefits of the combination. Food Funct. 2015, 6, 1496–1509. [CrossRef] [PubMed]
    • (2015) Food Funct , vol.6 , pp. 1496-1509
    • Rosenblat, M.1    Volkova, N.2    Borochov-Neori, H.3    Judeinstein, S.4    Aviram, M.5
  • 56
    • 85034078465 scopus 로고    scopus 로고
    • Impact of daily strawberry consumption on blood pressure and arterial stiffness in pre-and stage 1-hypertensive postmenopausal women: A randomized controlled trial
    • Feresin, R.G.; Johnson, S.A.; Pourafshar, S.; Campbell, J.C.; Jaime, S.J.; Navaei, N.; Elam, M.L.; Akhavan, N.S.; Alvarez-Alvarado, S.; Tenenbaum, G.; et al. Impact of daily strawberry consumption on blood pressure and arterial stiffness in pre-and stage 1-hypertensive postmenopausal women: A randomized controlled trial. Food Funct. 2017, 8, 4139–4149. [CrossRef]
    • (2017) Food Funct , vol.8 , pp. 4139-4149
    • Feresin, R.G.1    Johnson, S.A.2    Pourafshar, S.3    Campbell, J.C.4    Jaime, S.J.5    Navaei, N.6    Elam, M.L.7    Akhavan, N.S.8    Alvarez-Alvarado, S.9    Tenenbaum, G.10
  • 59
    • 84896874935 scopus 로고    scopus 로고
    • Polyphenol-rich apple (Malus domestica L.) peel extract attenuates arsenic trioxide induced cardiotoxicity in H9c2 cells via its antioxidant activity
    • Vineetha, V.P.; Girija, S.; Soumya, R.S.; Raghu, K.G. Polyphenol-rich apple (Malus domestica L.) peel extract attenuates arsenic trioxide induced cardiotoxicity in H9c2 cells via its antioxidant activity. Food Funct. 2014, 5, 502–511. [CrossRef] [PubMed]
    • (2014) Food Funct , vol.5 , pp. 502-511
    • Vineetha, V.P.1    Girija, S.2    Soumya, R.S.3    Raghu, K.G.4
  • 60
    • 84863846774 scopus 로고    scopus 로고
    • Effects of blackcurrant-based juice on atherosclerosis-related biomarkers in cultured macrophages and in human subjects after consumption of a high-energy meal
    • Huebbe, P.; Giller, K.; de Pascual-Teresa, S.; Arkenau, A.; Adolphi, B.; Portius, S.; Arkenau, C.N.; Rimbach, G. Effects of blackcurrant-based juice on atherosclerosis-related biomarkers in cultured macrophages and in human subjects after consumption of a high-energy meal. Br. J. Nutr. 2012, 108, 234–244. [CrossRef]
    • (2012) Br. J. Nutr. , vol.108 , pp. 234-244
    • Huebbe, P.1    Giller, K.2    de Pascual-Teresa, S.3    Arkenau, A.4    Adolphi, B.5    Portius, S.6    Arkenau, C.N.7    Rimbach, G.8
  • 61
    • 77955852925 scopus 로고    scopus 로고
    • Bilberry juice modulates plasma concentration of NF-kappaB related inflammatory markers in subjects at increased risk of CVD
    • Karlsen, A.; Paur, I.; Bohn, S.K.; Sakhi, A.K.; Borge, G.I.; Serafini, M.; Erlund, I.; Laake, P.; Tonstad, S.; Blomhoff, R. Bilberry juice modulates plasma concentration of NF-kappaB related inflammatory markers in subjects at increased risk of CVD. Eur. J. Nutr. 2010, 49, 345–355. [CrossRef] [PubMed]
    • (2010) Eur. J. Nutr. , vol.49 , pp. 345-355
    • Karlsen, A.1    Paur, I.2    Bohn, S.K.3    Sakhi, A.K.4    Borge, G.I.5    Serafini, M.6    Erlund, I.7    Laake, P.8    Tonstad, S.9    Blomhoff, R.10
  • 62
    • 84980390287 scopus 로고    scopus 로고
    • Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia
    • Yang, F.; Suo, Y.; Chen, D.; Tong, L. Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia. Biosci. Trends 2016, 10, 188–196. [CrossRef] [PubMed]
    • (2016) Biosci. Trends , vol.10 , pp. 188-196
    • Yang, F.1    Suo, Y.2    Chen, D.3    Tong, L.4
  • 64
    • 85012113124 scopus 로고    scopus 로고
    • Passiflora tarminiana fruits reduce UVB-induced photoaging in human skin fibroblasts
    • Bravo, K.; Duque, L.; Ferreres, F.; Moreno, D.A.; Osorio, E. Passiflora tarminiana fruits reduce UVB-induced photoaging in human skin fibroblasts. J. Photochem. Photobiol. B 2017, 168, 78–88. [CrossRef] [PubMed]
    • (2017) J. Photochem. Photobiol. B , vol.168 , pp. 78-88
    • Bravo, K.1    Duque, L.2    Ferreres, F.3    Moreno, D.A.4    Osorio, E.5
  • 65
    • 84938091747 scopus 로고    scopus 로고
    • 14 Days of supplementation with blueberry extract shows anti-atherogenic properties and improves oxidative parameters in hypercholesterolemic rats model
    • Stroher, D.J.; Escobar Piccoli Jda, C.; Gullich, A.A.; Pilar, B.C.; Coelho, R.P.; Bruno, J.B.; Faoro, D.; Manfredini, V. 14 Days of supplementation with blueberry extract shows anti-atherogenic properties and improves oxidative parameters in hypercholesterolemic rats model. Int. J. Food Sci. Nutr. 2015, 66, 559–568. [CrossRef] [PubMed]
    • (2015) Int. J. Food Sci. Nutr. , vol.66 , pp. 559-568
    • Stroher, D.J.1    Escobar Piccoli Jda, C.2    Gullich, A.A.3    Pilar, B.C.4    Coelho, R.P.5    Bruno, J.B.6    Faoro, D.7    Manfredini, V.8
  • 66
    • 77956569393 scopus 로고    scopus 로고
    • Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression
    • Wu, X.; Kang, J.; Xie, C.; Burris, R.; Ferguson, M.E.; Badger, T.M.; Nagarajan, S. Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression. J. Nutr. 2010, 140, 1628–1632. [CrossRef] [PubMed]
    • (2010) J. Nutr. , vol.140 , pp. 1628-1632
    • Wu, X.1    Kang, J.2    Xie, C.3    Burris, R.4    Ferguson, M.E.5    Badger, T.M.6    Nagarajan, S.7
  • 67
    • 84925938790 scopus 로고    scopus 로고
    • Strawberry extract presents antiplatelet activity by inhibition of inflammatory mediator of atherosclerosis (SP-selectin, sCD40L, RANTES, and IL-1beta) and thrombus formation
    • Alarcon, M.; Fuentes, E.; Olate, N.; Navarrete, S.; Carrasco, G.; Palomo, I. Strawberry extract presents antiplatelet activity by inhibition of inflammatory mediator of atherosclerosis (sP-selectin, sCD40L, RANTES, and IL-1beta) and thrombus formation. Platelets 2015, 26, 224–229. [CrossRef] [PubMed]
    • (2015) Platelets , vol.26 , pp. 224-229
    • Alarcon, M.1    Fuentes, E.2    Olate, N.3    Navarrete, S.4    Carrasco, G.5    Palomo, I.6
  • 68
    • 84898415598 scopus 로고    scopus 로고
    • Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: A randomized double-blind controlled trial
    • Moazen, S.; Amani, R.; Homayouni Rad, A.; Shahbazian, H.; Ahmadi, K.; Taha Jalali, M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: A randomized double-blind controlled trial. Ann. Nutr. Metab. 2013, 63, 256–264. [CrossRef] [PubMed]
    • (2013) Ann. Nutr. Metab. , vol.63 , pp. 256-264
    • Moazen, S.1    Amani, R.2    Homayouni Rad, A.3    Shahbazian, H.4    Ahmadi, K.5    Taha Jalali, M.6
  • 69
    • 77955974733 scopus 로고    scopus 로고
    • Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome
    • Basu, A.; Fu, D.X.; Wilkinson, M.; Simmons, B.; Wu, M.; Betts, N.M.; Du, M.; Lyons, T.J. Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome. Nutr. Res. 2010, 30, 462–469. [CrossRef]
    • (2010) Nutr. Res. , vol.30 , pp. 462-469
    • Basu, A.1    Fu, D.X.2    Wilkinson, M.3    Simmons, B.4    Wu, M.5    Betts, N.M.6    Du, M.7    Lyons, T.J.8
  • 70
    • 84973650054 scopus 로고    scopus 로고
    • Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes: A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial
    • An, J.H.; Kim, D.L.; Lee, T.B.; Kim, K.J.; Kim, S.H.; Kim, N.H.; Kim, H.Y.; Choi, D.S.; Kim, S.G. Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes: A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial. Phytother. Res. 2016, 30, 1634–1640. [CrossRef]
    • (2016) Phytother. Res. , vol.30 , pp. 1634-1640
    • An, J.H.1    Kim, D.L.2    Lee, T.B.3    Kim, K.J.4    Kim, S.H.5    Kim, N.H.6    Kim, H.Y.7    Choi, D.S.8    Kim, S.G.9
  • 71
    • 79961015677 scopus 로고    scopus 로고
    • Raspberry juice consumption, oxidative stress and reduction of atherosclerosis risk factors in hypercholesterolemic golden Syrian hamsters
    • Suh, J.H.; Romain, C.; Gonzalez-Barrio, R.; Cristol, J.P.; Teissedre, P.L.; Crozier, A.; Rouanet, J.M. Raspberry juice consumption, oxidative stress and reduction of atherosclerosis risk factors in hypercholesterolemic golden Syrian hamsters. Food Funct. 2011, 2, 400–405. [CrossRef] [PubMed]
    • (2011) Food Funct , vol.2 , pp. 400-405
    • Suh, J.H.1    Romain, C.2    Gonzalez-Barrio, R.3    Cristol, J.P.4    Teissedre, P.L.5    Crozier, A.6    Rouanet, J.M.7
  • 72
    • 85013867818 scopus 로고    scopus 로고
    • Acai (Euterpe oleracea Mart.) dietary intake affects plasma lipids, apolipoproteins, cholesteryl ester transfer to high-density lipoprotein and redox metabolism: A prospective study in women
    • Pala, D.; Barbosa, P.O.; Silva, C.T.; de Souza, M.O.; Freitas, F.R.; Volp, A.C.P.; Maranhao, R.C.; Freitas, R.N. Acai (Euterpe oleracea Mart.) dietary intake affects plasma lipids, apolipoproteins, cholesteryl ester transfer to high-density lipoprotein and redox metabolism: A prospective study in women. Clin. Nutr. 2018, 37, 618–623. [CrossRef] [PubMed]
    • (2018) Clin. Nutr , vol.37 , pp. 618-623
    • Pala, D.1    Barbosa, P.O.2    Silva, C.T.3    de Souza, M.O.4    Freitas, F.R.5    Volp, A.C.P.6    Maranhao, R.C.7    Freitas, R.N.8
  • 74
    • 85048313669 scopus 로고    scopus 로고
    • Fruit and vegetables in hypertensive women with asymptomatic peripheral arterial disease
    • Mattioli, A.V.; Francesca, C.; Mario, M.; Alberto, F. Fruit and vegetables in hypertensive women with asymptomatic peripheral arterial disease. Clin. Nutr. ESPEN 2018, 27, 110–112. [CrossRef] [PubMed]
    • (2018) Clin. Nutr. ESPEN , vol.27 , pp. 110-112
    • Mattioli, A.V.1    Francesca, C.2    Mario, M.3    Alberto, F.4
  • 76
    • 85037649478 scopus 로고    scopus 로고
    • Joint Effects of PON1 Polymorphisms and Vegetable Intake on Ischemic Stroke: A Family-Based Case Control Study
    • Juan, J.; Jiang, X.; Tang, X.; Wu, Y.; Sun, K.; Xiang, X.; Tian, Y.; Wu, T.; Sun, Q.; Kraft, P.; et al. Joint Effects of PON1 Polymorphisms and Vegetable Intake on Ischemic Stroke: A Family-Based Case Control Study. Int. J. Mol. Sci. 2017, 18, 2652. [CrossRef] [PubMed]
    • (2017) Int. J. Mol. Sci. , vol.18 , pp. 2652
    • Juan, J.1    Jiang, X.2    Tang, X.3    Wu, Y.4    Sun, K.5    Xiang, X.6    Tian, Y.7    Wu, T.8    Sun, Q.9    Kraft, P.10
  • 77
    • 85047193126 scopus 로고    scopus 로고
    • Influence of Dietary Patterns and Inflammatory Markers on Atherosclerosis Using Ankle Brachial Index as a Surrogate
    • Woo, J.; Yu, B.W.M.; Chan, R.S.M.; Leung, J. Influence of Dietary Patterns and Inflammatory Markers on Atherosclerosis Using Ankle Brachial Index as a Surrogate. J. Nutr. Health Aging 2018, 22, 619–626. [CrossRef]
    • (2018) J. Nutr. Health Aging , vol.22 , pp. 619-626
    • Woo, J.1    Yu, B.W.M.2    Chan, R.S.M.3    Leung, J.4
  • 80
    • 85034049201 scopus 로고    scopus 로고
    • A serving of blueberry (V. corymbosum) acutely improves peripheral arterial dysfunction in young smokers and non-smokers: Two randomized, controlled, crossover pilot studies
    • Del Bo, C.; Deon, V.; Campolo, J.; Lanti, C.; Parolini, M.; Porrini, M.; Klimis-Zacas, D.; Riso, P. A serving of blueberry (V. corymbosum) acutely improves peripheral arterial dysfunction in young smokers and non-smokers: Two randomized, controlled, crossover pilot studies. Food Funct. 2017, 8, 4108–4117. [CrossRef]
    • (2017) Food Funct , vol.8 , pp. 4108-4117
    • Del Bo, C.1    Deon, V.2    Campolo, J.3    Lanti, C.4    Parolini, M.5    Porrini, M.6    Klimis-Zacas, D.7    Riso, P.8
  • 81
    • 79952066487 scopus 로고    scopus 로고
    • Chemistry and biochemistry of dietary polyphenols
    • Tsao, R. Chemistry and biochemistry of dietary polyphenols. Nutrients 2010, 2, 1231–1246. [CrossRef] [PubMed]
    • (2010) Nutrients , vol.2 , pp. 1231-1246
    • Tsao, R.1
  • 82
    • 37549011857 scopus 로고    scopus 로고
    • Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase
    • Steffen, Y.; Gruber, C.; Schewe, T.; Sies, H. Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. Arch. Biochem. Biophys. 2008, 469, 209–219. [CrossRef] [PubMed]
    • (2008) Arch. Biochem. Biophys. , vol.469 , pp. 209-219
    • Steffen, Y.1    Gruber, C.2    Schewe, T.3    Sies, H.4
  • 83
    • 85034421842 scopus 로고    scopus 로고
    • Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats
    • Jin, L.; Piao, Z.H.; Sun, S.; Liu, B.; Kim, G.R.; Seok, Y.M.; Lin, M.Q.; Ryu, Y.; Choi, S.Y.; Kee, H.J.; et al. Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats. Sci. Rep. 2017, 7, 15607. [CrossRef] [PubMed]
    • (2017) Sci. Rep. , vol.7
    • Jin, L.1    Piao, Z.H.2    Sun, S.3    Liu, B.4    Kim, G.R.5    Seok, Y.M.6    Lin, M.Q.7    Ryu, Y.8    Choi, S.Y.9    Kee, H.J.10
  • 84
    • 84890278710 scopus 로고    scopus 로고
    • Regulatory mechanism of gallic acid against advanced glycation end products induced cardiac remodeling in experimental rats
    • Umadevi, S.; Gopi, V.; Elangovan, V. Regulatory mechanism of gallic acid against advanced glycation end products induced cardiac remodeling in experimental rats. Chem. Biol. Interact. 2014, 208, 28–36. [CrossRef] [PubMed]
    • (2014) Chem. Biol. Interact. , vol.208 , pp. 28-36
    • Umadevi, S.1    Gopi, V.2    Elangovan, V.3
  • 87
    • 84903187818 scopus 로고    scopus 로고
    • Luteolin protects HUVECs from TNF-alpha-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-kappaB and MAPK pathways
    • Xia, F.; Wang, C.; Jin, Y.; Liu, Q.; Meng, Q.; Liu, K.; Sun, H. Luteolin protects HUVECs from TNF-alpha-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-kappaB and MAPK pathways. J. Atheroscler. Thromb. 2014, 21, 768–783. [CrossRef] [PubMed]
    • (2014) J. Atheroscler. Thromb. , vol.21 , pp. 768-783
    • Xia, F.1    Wang, C.2    Jin, Y.3    Liu, Q.4    Meng, Q.5    Liu, K.6    Sun, H.7
  • 88
    • 84927696925 scopus 로고    scopus 로고
    • Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IKappaBalpha/NF-kappaB signaling pathway
    • Jia, Z.; Nallasamy, P.; Liu, D.; Shah, H.; Li, J.Z.; Chitrakar, R.; Si, H.; McCormick, J.; Zhu, H.; Zhen, W.; et al. Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IKappaBalpha/NF-kappaB signaling pathway. J. Nutr. Biochem. 2015, 26, 293–302. [CrossRef]
    • (2015) J. Nutr. Biochem. , vol.26 , pp. 293-302
    • Jia, Z.1    Nallasamy, P.2    Liu, D.3    Shah, H.4    Li, J.Z.5    Chitrakar, R.6    Si, H.7    McCormick, J.8    Zhu, H.9    Zhen, W.10
  • 89
    • 84893737264 scopus 로고    scopus 로고
    • Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation
    • Lamy, S.; Ouanouki, A.; Beliveau, R.; Desrosiers, R.R. Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation. Exp. Cell Res. 2014, 322, 89–98. [CrossRef]
    • (2014) Exp. Cell Res. , vol.322 , pp. 89-98
    • Lamy, S.1    Ouanouki, A.2    Beliveau, R.3    Desrosiers, R.R.4
  • 90
    • 84891615140 scopus 로고    scopus 로고
    • Hydroxytyrosol suppresses MMP-9 and COX-2 activity and expression in activated human monocytes via PKCalpha and PKCbeta1 inhibition
    • Scoditti, E.; Nestola, A.; Massaro, M.; Calabriso, N.; Storelli, C.; De Caterina, R.; Carluccio, M.A. Hydroxytyrosol suppresses MMP-9 and COX-2 activity and expression in activated human monocytes via PKCalpha and PKCbeta1 inhibition. Atherosclerosis 2014, 232, 17–24. [CrossRef]
    • (2014) Atherosclerosis , vol.232 , pp. 17-24
    • Scoditti, E.1    Nestola, A.2    Massaro, M.3    Calabriso, N.4    Storelli, C.5    de Caterina, R.6    Carluccio, M.A.7
  • 92
    • 84908662080 scopus 로고    scopus 로고
    • Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1
    • Storniolo, C.E.; Rosello-Catafau, J.; Pinto, X.; Mitjavila, M.T.; Moreno, J.J. Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1. Redox Boil. 2014, 2, 971–977. [CrossRef] [PubMed]
    • (2014) Redox Boil , vol.2 , pp. 971-977
    • Storniolo, C.E.1    Rosello-Catafau, J.2    Pinto, X.3    Mitjavila, M.T.4    Moreno, J.J.5
  • 93
    • 84867101055 scopus 로고    scopus 로고
    • Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer
    • Scoditti, E.; Calabriso, N.; Massaro, M.; Pellegrino, M.; Storelli, C.; Martines, G.; De Caterina, R.; Carluccio, M.A. Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch. Biochem. Biophys. 2012, 527, 81–89. [CrossRef] [PubMed]
    • (2012) Arch. Biochem. Biophys. , vol.527 , pp. 81-89
    • Scoditti, E.1    Calabriso, N.2    Massaro, M.3    Pellegrino, M.4    Storelli, C.5    Martines, G.6    de Caterina, R.7    Carluccio, M.A.8
  • 94
    • 77951191817 scopus 로고    scopus 로고
    • Reactive oxygen generated by NADPH oxidase 1 (Nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration
    • Shinohara, M.; Adachi, Y.; Mitsushita, J.; Kuwabara, M.; Nagasawa, A.; Harada, S.; Furuta, S.; Zhang, Y.; Seheli, K.; Miyazaki, H.; et al. Reactive oxygen generated by NADPH oxidase 1 (Nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration. J. Biol. Chem. 2010, 285, 4481–4488. [CrossRef] [PubMed]
    • (2010) J. Biol. Chem. , vol.285 , pp. 4481-4488
    • Shinohara, M.1    Adachi, Y.2    Mitsushita, J.3    Kuwabara, M.4    Nagasawa, A.5    Harada, S.6    Furuta, S.7    Zhang, Y.8    Seheli, K.9    Miyazaki, H.10
  • 95
    • 0642373569 scopus 로고    scopus 로고
    • Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: Critical role of NADPH oxidase
    • Barbieri, S.S.; Eligini, S.; Brambilla, M.; Tremoli, E.; Colli, S. Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: Critical role of NADPH oxidase. Cardiovasc. Res. 2003, 60, 187–197. [CrossRef]
    • (2003) Cardiovasc. Res. , vol.60 , pp. 187-197
    • Barbieri, S.S.1    Eligini, S.2    Brambilla, M.3    Tremoli, E.4    Colli, S.5
  • 96
    • 73749086768 scopus 로고    scopus 로고
    • Effects of red grape juice polyphenols in NADPH oxidase subunit expression in human neutrophils and mononuclear blood cells
    • Davalos, A.; de la Pena, G.; Sanchez-Martin, C.C.; Teresa Guerra, M.; Bartolome, B.; Lasuncion, M.A. Effects of red grape juice polyphenols in NADPH oxidase subunit expression in human neutrophils and mononuclear blood cells. Br. J. Nutr. 2009, 102, 1125–1135. [CrossRef] [PubMed]
    • (2009) Br. J. Nutr. , vol.102 , pp. 1125-1135
    • Davalos, A.1    de la Pena, G.2    Sanchez-Martin, C.C.3    Teresa Guerra, M.4    Bartolome, B.5    Lasuncion, M.A.6
  • 97
    • 77950469163 scopus 로고    scopus 로고
    • Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4)
    • Spanier, G.; Xu, H.; Xia, N.; Tobias, S.; Deng, S.; Wojnowski, L.; Forstermann, U.; Li, H. Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4). J. Physiol. Pharmacol. 2009, 60 (Suppl. 4), 111–116.
    • (2009) J. Physiol. Pharmacol. , vol.60 , pp. 111-116
    • Spanier, G.1    Xu, H.2    Xia, N.3    Tobias, S.4    Deng, S.5    Wojnowski, L.6    Forstermann, U.7    Li, H.8
  • 99
    • 84862215866 scopus 로고    scopus 로고
    • Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms
    • Tang, Y.; Xu, J.; Qu, W.; Peng, X.; Xin, P.; Yang, X.; Ying, C.; Sun, X.; Hao, L. Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms. J. Nutr. Biochem. 2012, 23, 1410–1416. [CrossRef]
    • (2012) J. Nutr. Biochem. , vol.23 , pp. 1410-1416
    • Tang, Y.1    Xu, J.2    Qu, W.3    Peng, X.4    Xin, P.5    Yang, X.6    Ying, C.7    Sun, X.8    Hao, L.9
  • 100
    • 85057983460 scopus 로고    scopus 로고
    • Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK
    • Wang, J.; Li, J.; Cao, N.; Li, Z.; Han, J.; Li, L. Resveratrol, an activator of SIRT1, induces protective autophagy in non-small-cell lung cancer via inhibiting Akt/mTOR and activating p38-MAPK. Onco Targets Ther. 2018, 11, 7777–7786. [CrossRef]
    • (2018) Onco Targets Ther , vol.11 , pp. 7777-7786
    • Wang, J.1    Li, J.2    Cao, N.3    Li, Z.4    Han, J.5    Li, L.6
  • 101
    • 85049527332 scopus 로고    scopus 로고
    • Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage
    • [CrossRef] [PubMed]
    • Gao, J.; Zhang, Q.; Song, L. Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage. Biosci. Rep. 2018, 38, BSR20180544. [CrossRef] [PubMed]
    • (2018) Biosci. Rep. , vol.38
    • Gao, J.1    Zhang, Q.2    Song, L.3
  • 102
    • 84915751046 scopus 로고    scopus 로고
    • Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling
    • Alayev, A.; Doubleday, P.F.; Berger, S.M.; Ballif, B.A.; Holz, M.K. Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling. J. Proteome Res. 2014, 13, 5734–5742. [CrossRef] [PubMed]
    • (2014) J. Proteome Res. , vol.13 , pp. 5734-5742
    • Alayev, A.1    Doubleday, P.F.2    Berger, S.M.3    Ballif, B.A.4    Holz, M.K.5
  • 103
    • 79952831059 scopus 로고    scopus 로고
    • Resveratrol blocks Akt activation in angiotensin II-or EGF-stimulated vascular smooth muscle cells in a redox-independent manner
    • Schreiner, C.E.; Kumerz, M.; Gesslbauer, J.; Schachner, D.; Joa, H.; Erker, T.; Atanasov, A.G.; Heiss, E.H.; Dirsch, V.M. Resveratrol blocks Akt activation in angiotensin II-or EGF-stimulated vascular smooth muscle cells in a redox-independent manner. Cardiovasc. Res. 2011, 90, 140–147. [CrossRef] [PubMed]
    • (2011) Cardiovasc. Res. , vol.90 , pp. 140-147
    • Schreiner, C.E.1    Kumerz, M.2    Gesslbauer, J.3    Schachner, D.4    Joa, H.5    Erker, T.6    Atanasov, A.G.7    Heiss, E.H.8    Dirsch, V.M.9
  • 104
    • 84896914528 scopus 로고    scopus 로고
    • Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK
    • Thompson, A.M.; Martin, K.A.; Rzucidlo, E.M. Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK. PLoS ONE 2014, 9, e85495. [CrossRef] [PubMed]
    • (2014) Plos ONE , vol.9
    • Thompson, A.M.1    Martin, K.A.2    Rzucidlo, E.M.3
  • 105
    • 0036784081 scopus 로고    scopus 로고
    • Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells
    • Haider, U.G.; Sorescu, D.; Griendling, K.K.; Vollmar, A.M.; Dirsch, V.M. Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol. Pharmacol. 2002, 62, 772–777. [CrossRef] [PubMed]
    • (2002) Mol. Pharmacol. , vol.62 , pp. 772-777
    • Haider, U.G.1    Sorescu, D.2    Griendling, K.K.3    Vollmar, A.M.4    Dirsch, V.M.5
  • 107
    • 0036197909 scopus 로고    scopus 로고
    • Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells
    • Klein, R.D.; Fischer, S.M. Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. Carcinogenesis 2002, 23, 217–221. [CrossRef] [PubMed]
    • (2002) Carcinogenesis , vol.23 , pp. 217-221
    • Klein, R.D.1    Fischer, S.M.2
  • 108
    • 84900805614 scopus 로고    scopus 로고
    • Delphinidin inhibits VEGF induced-mitochondrial biogenesis and Akt activation in endothelial cells
    • Duluc, L.; Jacques, C.; Soleti, R.; Andriantsitohaina, R.; Simard, G. Delphinidin inhibits VEGF induced-mitochondrial biogenesis and Akt activation in endothelial cells. Int. J. Biochem. Cell Biol. 2014, 53, 9–14. [CrossRef]
    • (2014) Int. J. Biochem. Cell Biol. , vol.53 , pp. 9-14
    • Duluc, L.1    Jacques, C.2    Soleti, R.3    Andriantsitohaina, R.4    Simard, G.5
  • 109
    • 85055633102 scopus 로고    scopus 로고
    • Targeting Autophagy in Aging and Aging-Related Cardiovascular Diseases
    • Ren, J.; Zhang, Y. Targeting Autophagy in Aging and Aging-Related Cardiovascular Diseases. Trends Pharmacol. Sci. 2018, 39, 1064–1076. [CrossRef]
    • (2018) Trends Pharmacol. Sci. , vol.39 , pp. 1064-1076
    • Ren, J.1    Zhang, Y.2
  • 110
    • 85042226943 scopus 로고    scopus 로고
    • Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants
    • Teixeira, J.; Deus, C.M.; Borges, F.; Oliveira, P.J. Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants. Int. J. Biochem. Cell Biol. 2018, 97, 98–103. [CrossRef]
    • (2018) Int. J. Biochem. Cell Biol. , vol.97 , pp. 98-103
    • Teixeira, J.1    Deus, C.M.2    Borges, F.3    Oliveira, P.J.4
  • 112
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
    • Lagouge, M.; Argmann, C.; Gerhart-Hines, Z.; Meziane, H.; Lerin, C.; Daussin, F.; Messadeq, N.; Milne, J.; Lambert, P.; Elliott, P.; et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 2006, 127, 1109–1122. [CrossRef] [PubMed]
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3    Meziane, H.4    Lerin, C.5    Daussin, F.6    Messadeq, N.7    Milne, J.8    Lambert, P.9    Elliott, P.10
  • 114
    • 85049032651 scopus 로고    scopus 로고
    • Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1
    • Khajevand-Khazaei, M.R.; Mohseni-Moghaddam, P.; Hosseini, M.; Gholami, L.; Baluchnejadmojarad, T.; Roghani, M. Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1. Eur. J. Pharmacol. 2018, 833, 307–313. [CrossRef] [PubMed]
    • (2018) Eur. J. Pharmacol. , vol.833 , pp. 307-313
    • Khajevand-Khazaei, M.R.1    Mohseni-Moghaddam, P.2    Hosseini, M.3    Gholami, L.4    Baluchnejadmojarad, T.5    Roghani, M.6
  • 115
    • 85046818282 scopus 로고    scopus 로고
    • Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats
    • Qiu, L.; Luo, Y.; Chen, X. Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats. Biomed. Pharmacother. 2018, 103, 1585–1591. [CrossRef] [PubMed]
    • (2018) Biomed. Pharmacother. , vol.103 , pp. 1585-1591
    • Qiu, L.1    Luo, Y.2    Chen, X.3
  • 117
    • 85044965469 scopus 로고    scopus 로고
    • (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells
    • Cremonini, E.; Oteiza, P.I. (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells. Arch. Biochem. Biophys. 2018, 646, 55–63. [CrossRef]
    • (2018) Arch. Biochem. Biophys. , vol.646 , pp. 55-63
    • Cremonini, E.1    Oteiza, P.I.2
  • 118
    • 85031702355 scopus 로고    scopus 로고
    • Effects of catechins and caffeine on the development of atherosclerosis in mice
    • Liu, L.; Nagai, I.; Gao, Y.; Matsushima, Y.; Kawai, Y.; Sayama, K. Effects of catechins and caffeine on the development of atherosclerosis in mice. Biosci. Biotechnol. Biochem. 2017, 81, 1948–1955. [CrossRef]
    • (2017) Biosci. Biotechnol. Biochem. , vol.81 , pp. 1948-1955
    • Liu, L.1    Nagai, I.2    Gao, Y.3    Matsushima, Y.4    Kawai, Y.5    Sayama, K.6
  • 119
    • 84924577160 scopus 로고    scopus 로고
    • Anti-atherosclerotic activity of catechins depends on their stereoisomerism
    • Mika, M.; Kostogrys, R.B.; Franczyk-Zarow, M.; Wikiera, A.; Maslak, E. Anti-atherosclerotic activity of catechins depends on their stereoisomerism. Atherosclerosis 2015, 240, 125–130. [CrossRef]
    • (2015) Atherosclerosis , vol.240 , pp. 125-130
    • Mika, M.1    Kostogrys, R.B.2    Franczyk-Zarow, M.3    Wikiera, A.4    Maslak, E.5
  • 120
    • 85016205558 scopus 로고    scopus 로고
    • Catechins as Potential Mediators of Cardiovascular Health
    • Mangels, D.R.; Mohler, E.R., 3rd. Catechins as Potential Mediators of Cardiovascular Health. Arterioscler. Thromb. Vasc. Biol. 2017, 37, 757–763. [CrossRef]
    • (2017) Arterioscler. Thromb. Vasc. Biol. , vol.37 , pp. 757-763
    • Mangels, D.R.1    Mohler, E.R.2
  • 122
    • 85045880291 scopus 로고    scopus 로고
    • The Role of Catechins in Cellular Responses to Oxidative Stress
    • Bernatoniene, J.; Kopustinskiene, D.M. The Role of Catechins in Cellular Responses to Oxidative Stress. Molecules 2018, 23, 965. [CrossRef] [PubMed]
    • (2018) Molecules , vol.23 , pp. 965
    • Bernatoniene, J.1    Kopustinskiene, D.M.2
  • 123
    • 84901054689 scopus 로고    scopus 로고
    • (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
    • Bettaieb, A.; Vazquez Prieto, M.A.; Rodriguez Lanzi, C.; Miatello, R.M.; Haj, F.G.; Fraga, C.G.; Oteiza, P.I. (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. Free Radic. Biol. Med. 2014, 72, 247–256. [CrossRef] [PubMed]
    • (2014) Free Radic. Biol. Med. , vol.72 , pp. 247-256
    • Bettaieb, A.1    Vazquez Prieto, M.A.2    Rodriguez Lanzi, C.3    Miatello, R.M.4    Haj, F.G.5    Fraga, C.G.6    Oteiza, P.I.7
  • 125
  • 126
    • 85034034558 scopus 로고    scopus 로고
    • (−)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance
    • Cremonini, E.; Wang, Z.; Bettaieb, A.; Adamo, A.M.; Daveri, E.; Mills, D.A.; Kalanetra, K.M.; Haj, F.G.; Karakas, S.; Oteiza, P.I. (−)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. Redox Boil. 2018, 14, 588–599. [CrossRef]
    • (2018) Redox Boil , vol.14 , pp. 588-599
    • Cremonini, E.1    Wang, Z.2    Bettaieb, A.3    Adamo, A.M.4    Daveri, E.5    Mills, D.A.6    Kalanetra, K.M.7    Haj, F.G.8    Karakas, S.9    Oteiza, P.I.10
  • 127
  • 128
    • 85016298004 scopus 로고    scopus 로고
    • Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase
    • Xiao, L.; Liu, L.; Guo, X.; Zhang, S.; Wang, J.; Zhou, F.; Liu, L.; Tang, Y.; Yao, P. Quercetin attenuates high fat diet-induced atherosclerosis in apolipoprotein E knockout mice: A critical role of NADPH oxidase. Food Chem. Toxicol. 2017, 105, 22–33. [CrossRef]
    • (2017) Food Chem. Toxicol. , vol.105 , pp. 22-33
    • Xiao, L.1    Liu, L.2    Guo, X.3    Zhang, S.4    Wang, J.5    Zhou, F.6    Liu, L.7    Tang, Y.8    Yao, P.9
  • 129
    • 84863011114 scopus 로고    scopus 로고
    • Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases
    • Park, S.J.; Ahmad, F.; Philp, A.; Baar, K.; Williams, T.; Luo, H.; Ke, H.; Rehmann, H.; Taussig, R.; Brown, A.L.; et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell 2012, 148, 421–433. [CrossRef]
    • (2012) Cell , vol.148 , pp. 421-433
    • Park, S.J.1    Ahmad, F.2    Philp, A.3    Baar, K.4    Williams, T.5    Luo, H.6    Ke, H.7    Rehmann, H.8    Taussig, R.9    Brown, A.L.10
  • 130
    • 84946472612 scopus 로고    scopus 로고
    • Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3
    • Bagul, P.K.; Deepthi, N.; Sultana, R.; Banerjee, S.K. Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3. J. Nutr. Biochem. 2015, 26, 1298–1307. [CrossRef]
    • (2015) J. Nutr. Biochem. , vol.26 , pp. 1298-1307
    • Bagul, P.K.1    Deepthi, N.2    Sultana, R.3    Banerjee, S.K.4
  • 131
    • 15444377466 scopus 로고    scopus 로고
    • SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
    • Bouras, T.; Fu, M.; Sauve, A.A.; Wang, F.; Quong, A.A.; Perkins, N.D.; Hay, R.T.; Gu, W.; Pestell, R.G. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J. Biol. Chem. 2005, 280, 10264–10276. [CrossRef] [PubMed]
    • (2005) J. Biol. Chem. , vol.280 , pp. 10264-10276
    • Bouras, T.1    Fu, M.2    Sauve, A.A.3    Wang, F.4    Quong, A.A.5    Perkins, N.D.6    Hay, R.T.7    Gu, W.8    Pestell, R.G.9
  • 132
    • 85052371951 scopus 로고    scopus 로고
    • Food Bioactive HDAC Inhibitors in the Epigenetic Regulation of Heart Failure
    • Evans, L.W.; Ferguson, B.S. Food Bioactive HDAC Inhibitors in the Epigenetic Regulation of Heart Failure. Nutrients 2018, 10, 1120. [CrossRef] [PubMed]
    • (2018) Nutrients , vol.10 , pp. 1120
    • Evans, L.W.1    Ferguson, B.S.2


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