Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells

Regulatory Peptides

Volumn 177, Issue 1-3, 2012, Pages 35-39

  Ichiki, Toshihiro ^a,b   Miyazaki, Ryohei ^a   Kamiharaguchi, Aya ^a   Hashimoto, Toru ^a   Matsuura, Hirohide ^a   Kitamoto, Shiro ^a,b   Tokunou, Tomotake ^a   Sunagawa, Kenji ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Angiotensin II; P53; Resveratrol; Senescence

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; PROTEIN P21; PROTEIN P53; RESVERATROL;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL AGING; CELL CULTURE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DOWN REGULATION; LIFE EXTENSION; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE CELL;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ASSAYS; IMIDAZOLES; LOSARTAN; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OXIDATIVE STRESS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; STILBENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84862759386     PISSN: 01670115     EISSN: 18731686     Source Type: Journal    
DOI: 10.1016/j.regpep.2012.04.005     Document Type: Article

References (22)

1. Renaud S., de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992, 339:1523-1526.
2. Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006, 5:493-506.
3. Wang Q., Xu J., Rottinghaus G.E., Simonyi A., Lubahn D., Sun G.Y., Sun A.Y. Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 2002, 958:439-447.
4. Jang M., Cai L., Udeani G.O., Slowing K.V., Thomas C.F., Beecher C.W., Fong H.H., Farnsworth N.R., Kinghorn A.D., Mehta R.G., Moon R.C., Pezzuto J.M. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997, 275:218-220.
5. Howitz K.T., Bitterman K.J., Cohen H.Y., Lamming D.W., Lavu S., Wood J.G., Zipkin R.E., Chung P., Kisielewski A., Zhang L.L., Scherer B., Sinclair D.A. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003, 425:191-196.
6. Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., Prabhu V.V., Allard J.S., Lopez-Lluch G., Lewis K., Pistell P.J., Poosala S., Becker K.G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K.W., Spencer R.G., Lakatta E.G., et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006, 444:337-342.
7. Sasaki K., Yamano Y., Bardhan S., Iwai N., Murray J.J., Hasegawa M., Matsuda Y., Inagami T. Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature 1991, 351:230-233.
8. Kambayashi Y., Bardhan S., Takahashi K., Tsuzuki S., Inui H., Hamakubo T., Inagami T. Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J Biol Chem 1993, 268:24543-24546.
9. Stegbauer J., Coffman T.M. New insights into angiotensin receptor actions: from blood pressure to aging. Curr Opin Nephrol Hypertens 2011, 20:84-88.
10. Minamino T., Yoshida T., Tateno K., Miyauchi H., Zou Y., Toko H., Komuro I. Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation 2003, 108:2264-2269.
11. Linz W., Heitsch H., Scholkens B.A., Wiemer G. Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats. Hypertension 2000, 35:908-913.
12. Minamino T., Komuro I. Vascular cell senescence: contribution to atherosclerosis. Circ Res 2007, 100:15-26.
13. Kunieda T., Minamino T., Nishi J., Tateno K., Oyama T., Katsuno T., Miyauchi H., Orimo M., Okada S., Takamura M., Nagai T., Kaneko S., Komuro I. Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation 2006, 114:953-960.
14. Mnjoyan Z.H., Fujise K. Profound negative regulatory effects by resveratrol on vascular smooth muscle cells: a role of p53-p21(WAF1/CIP1) pathway. Biochem Biophys Res Commun 2003, 311:546-552.
15. Zheng J.P., Ju D., Jiang H., Shen J., Yang M., Li L. Resveratrol induces p53 and suppresses myocardin-mediated vascular smooth muscle cell differentiation. Toxicol Lett 2010, 199:115-122.
16. Herbert K.E., Mistry Y., Hastings R., Poolman T., Niklason L., Williams B. Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways. Circ Res 2008, 102:201-208.
17. Fukao H., Ijiri Y., Miura M., Hashimoto M., Yamashita T., Fukunaga C., Oiwa K., Kawai Y., Suwa M., Yamamoto J. Effect of trans-resveratrol on the thrombogenicity and atherogenicity in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice. Blood Coagul Fibrinolysis 2004, 15:441-446.
18. Miyazaki R., Ichiki T., Hashimoto T., Inanaga K., Imayama I., Sadoshima J., Sunagawa K. SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 2008, 28:1263-1269.
19. Brooks CL, Gu W. The impact of acetylation and deacetylation on the p53 pathway. Protein Cell;2:456-462.
20. Benigni A., Corna D., Zoja C., Sonzogni A., Latini R., Salio M., Conti S., Rottoli D., Longaretti L., Cassis P., Morigi M., Coffman T.M., Remuzzi G. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 2009, 119:524-530.
21. Lekli I., Ray D., Das D.K. Longevity nutrients resveratrol, wines and grapes. Genes Nutr 2010, 5:55-60.
22. Li Y., Cao Z., Zhu H. Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress. Pharmacol Res 2006, 53:6-15.