PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases

Cell Reports

Volumn 12, Issue 9, 2015, Pages 1391-1399

  Xiong, Shiqin ^a   Patrushev, Nikolay ^a   Forouzandeh, Farshad ^a   Hilenski, Lula ^a   Alexander, R Wayne ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P53; TELOMERASE REVERSE TRANSCRIPTASE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2; NFE2L2 PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; TELOMERASE; TERT PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADULT; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DISEASE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CELL PROTECTION; CHROMOSOME DISORDER; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DAMAGE; ELECTROPHILICITY; GENE FUNCTION; LIPID DIET; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; TELOMERE SHORTENING; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; VASCULAR DISEASE; ANIMAL; ANTIOXIDANT RESPONSIVE ELEMENT; BLOOD VESSEL; C57BL MOUSE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOLOGY; TELOMERE;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ATHEROSCLEROSIS; BLOOD VESSELS; DNA DAMAGE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; TELOMERASE; TELOMERE; TELOMERE SHORTENING; THIOCTIC ACID; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84940786859     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.07.047     Document Type: Article

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