CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms

Nature Reviews Microbiology

Volumn 16, Issue 6, 2018, Pages 333-339

  Shapiro, Rebecca S ^a,b,c   Chavez, Alejandro ^d   Collins, James J ^a,b,e  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF GUELPH   (Canada)

^d Columbia University College of Physicians and Surgeons ^*  (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; GUIDE RNA; RIBONUCLEOPROTEIN; RNA BINDING PROTEIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE; BACTERIAL DNA;

ANTIBIOTIC RESISTANCE; ANTIFUNGAL RESISTANCE; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CRISPR-CAS9 SYSTEM; CRYPTOSPORIDIUM PARVUM; DNA END JOINING REPAIR; ESSENTIAL GENE; FILAMENTOUS FUNGUS; FUNCTIONAL GENOMICS; GENE DELETION; GENE DISRUPTION; GENE EDITING; GENE FUNCTION; GENE INTERACTION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC MANIPULATION; HOMOLOGOUS RECOMBINATION; HYPOCREA JECORINA; INDEL MUTATION; KOMAGATAELLA PASTORIS; LEISHMANIA DONOVANI; LOSS OF FUNCTION MUTATION; METAGENOMICS; MYCELIOPHTHORA THERMOPHILA; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PENICILLIUM CHRYSOGENUM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STOP CODON; TOXOPLASMA GONDII; TRYPANOSOMA CRUZI; YARROWIA LIPOLYTICA; BACTERIAL GENOME; BACTERIUM; CRISPR CAS SYSTEM; GENETIC ENGINEERING; GENETICS; GENOMICS; PROCEDURES;

BACTERIA; CRISPR-CAS SYSTEMS; DNA, BACTERIAL; GENETIC ENGINEERING; GENOME, BACTERIAL; GENOMICS;

EID: 85044589051     PISSN: 17401526     EISSN: 17401534     Source Type: Journal    
DOI: 10.1038/s41579-018-0002-7     Document Type: Article

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