A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

Nature Microbiology

Volumn 3, Issue 1, 2017, Pages 73-82

  Shapiro, Rebecca S ^a,b,c   Chavez, Alejandro ^c,d,e,k   Porter, Caroline B M ^a,b   Hamblin, Meagan ^b   Kaas, Christian S ^c,e,f   DiCarlo, James E ^e,g   Zeng, Guisheng ^h   Xu, Xiaoli ^h   Revtovich, Alexey V ⁱ   Kirienko, Natalia V ⁱ   Wang, Yue ^h,j   Church, George M ^c,e   Collins, James J ^a,b,c  

^a Massachusetts Institute of Technology   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c HARVARD UNIVERSITY   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f NOVO NORDISK A S   (Denmark)

^g Columbia University ^*  (United States)

^h INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

ⁱ RICE UNIVERSITY   (United States)

^j NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^k Columbia University College of Physicians ^*  (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; BIOFILM; CANDIDA ALBICANS; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; DELETION MUTANT; DIPLOIDY; FEMALE; FUNGAL STRAIN; FUNGAL VIRULENCE; GENE DELETION; GENE INTERACTION; GENE LIBRARY; GENE LOCUS; GENE TARGETING; MATING TYPE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WILD TYPE; CRISPR CAS SYSTEM; DRUG EFFECT; GENE DRIVE TECHNOLOGY; GENE EXPRESSION REGULATION; GENETIC PROCEDURES; GENETICS; GROWTH, DEVELOPMENT AND AGING; HIGH THROUGHPUT SCREENING; HOMOZYGOTE; VIRULENCE;

FLUCONAZOLE; FUNGAL PROTEIN;

BIOFILMS; CANDIDA ALBICANS; CRISPR-CAS SYSTEMS; FLUCONAZOLE; FUNGAL PROTEINS; GENE DELETION; GENE DRIVE TECHNOLOGY; GENE EXPRESSION REGULATION, FUNGAL; GENETIC TECHNIQUES; HIGH-THROUGHPUT SCREENING ASSAYS; HOMOZYGOTE; VIRULENCE;

EID: 85031896257     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/s41564-017-0043-0     Document Type: Article

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