A comprehensive, CRISPR-based functional analysis of essential genes in bacteria

Cell

Volumn 165, Issue 6, 2016, Pages 1493-1506

  Peters, Jason M ^a   Colavin, Alexandre ^b   Shi, Handuo ^c   Czarny, Tomasz L ^d   Larson, Matthew H ^a,e,f,g   Wong, Spencer ^a   Hawkins, John S ^a,e   Lu, Candy H S ^a   Koo, Byoung Mo ^a   Marta, Elizabeth ^a   Shiver, Anthony L ^a,e   Whitehead, Evan H ^a,e,f   Weissman, Jonathan S ^a,e,f,g   Brown, Eric D ^d   Qi, Lei S ^b,c   Huang, Kerwyn Casey ^b,c,h   Gross, Carol A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

^c Stanford University   (United States)

^d MCMASTER UNIVERSITY   (Canada)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; CELL GROWTH; CELL SHAPE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; ESSENTIAL GENE; GENE FUNCTION; GENE SILENCING; GENETIC ANALYSIS; GROWTH RATE; MICROSCOPY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; CRISPR CAS SYSTEM; GENE LIBRARY; GENE REGULATORY NETWORK; GENETICS; MOLECULARLY TARGETED THERAPY;

BACILLUS SUBTILIS; CRISPR-CAS SYSTEMS; GENE KNOCKDOWN TECHNIQUES; GENE LIBRARY; GENE REGULATORY NETWORKS; GENES, BACTERIAL; GENES, ESSENTIAL; MOLECULAR TARGETED THERAPY;

EID: 84969916078     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.05.003     Document Type: Article

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