Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Nature Microbiology

Volumn 2, Issue , 2017, Pages

  Rock, Jeremy M ^a   Hopkins, Forrest F ^a   Chavez, Alejandro ^b,c,d   Diallo, Marieme ^a   Chase, Michael R ^a   Gerrick, Elias R ^a   Pritchard, Justin R ^a   Church, George M ^b,d   Rubin, Eric J ^a   Sassetti, Christopher M ^e   Schnappinger, Dirk ^f   Fortune, Sarah M ^a,g  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF MASSACHUSETTS   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; ENDONUCLEASE;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; GENE EXPRESSION; GENE KNOCKDOWN; GENE SILENCING; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; OPERON; STREPTOCOCCUS PYOGENES; STREPTOCOCCUS THERMOPHILUS; TRANSCRIPTION INITIATION SITE;

BACTERIAL PROTEINS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; ENDONUCLEASES; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GENETIC TECHNIQUES; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; OPERON; STREPTOCOCCUS PYOGENES; STREPTOCOCCUS THERMOPHILUS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 85011705463     PISSN: None     EISSN: 20585276     Source Type: Journal    
DOI: 10.1038/nmicrobiol.2016.274     Document Type: Article

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