CRISPR-Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters

Nature Chemical Biology

Volumn 13, Issue 6, 2017, Pages 607-609

  Zhang, Mingzi M ^a   Wong, Fong Tian ^b   Wang, Yajie ^c   Luo, Shangwen ^c   Lim, Yee Hwee ^d   Heng, Elena ^b   Yeo, Wan Lin ^a   Cobb, Ryan E ^c   Enghiad, Behnam ^c   Ang, Ee Lui ^a   Zhao, Huimin ^a,c  

^a Agency for Science   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CRISPR CAS SYSTEM; GENE CLUSTER; GENETIC MANIPULATION; HETEROLOGOUS EXPRESSION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOLOGOUS RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; STREPTOMYCES; STREPTOMYCES ALBUS; STREPTOMYCES GRISEUS; STREPTOMYCES LAVENDULAE; STREPTOMYCES VIRIDOCHROMOGENES; STREPTOMYCETACEAE;

EID: 85017266739     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2341     Document Type: Article

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