-
2
-
-
84940502214
-
Predicting effective microRNA target sites in mammalian mRNAs
-
Agarwal, V., Bell, G.W., Nam, J.W., Bartel, D.P., Predicting effective microRNA target sites in mammalian mRNAs. eLife, 4, 2015, 4.
-
(2015)
eLife
, vol.4
, pp. 4
-
-
Agarwal, V.1
Bell, G.W.2
Nam, J.W.3
Bartel, D.P.4
-
3
-
-
37648998629
-
Getting to the root of miRNA-mediated gene silencing
-
Eulalio, A., Huntzinger, E., Izaurralde, E., Getting to the root of miRNA-mediated gene silencing. Cell 132 (2008), 9–14.
-
(2008)
Cell
, vol.132
, pp. 9-14
-
-
Eulalio, A.1
Huntzinger, E.2
Izaurralde, E.3
-
4
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., Ingolia, N.T., Weissman, J.S., Bartel, D.P., Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466 (2010), 835–840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
5
-
-
79961170994
-
A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?
-
Salmena, L., Poliseno, L., Tay, Y., Kats, L., Pandolfi, P.P., A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?. Cell 146 (2011), 353–358.
-
(2011)
Cell
, vol.146
, pp. 353-358
-
-
Salmena, L.1
Poliseno, L.2
Tay, Y.3
Kats, L.4
Pandolfi, P.P.5
-
6
-
-
77953957633
-
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
-
Poliseno, L., Salmena, L., Zhang, J., Carver, B., Haveman, W.J., Pandolfi, P.P., A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 465 (2010), 1033–1038.
-
(2010)
Nature
, vol.465
, pp. 1033-1038
-
-
Poliseno, L.1
Salmena, L.2
Zhang, J.3
Carver, B.4
Haveman, W.J.5
Pandolfi, P.P.6
-
7
-
-
80054715378
-
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
-
Cesana, M., Cacchiarelli, D., Legnini, I., Santini, T., Sthandier, O., Chinappi, M., et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 147 (2011), 358–369.
-
(2011)
Cell
, vol.147
, pp. 358-369
-
-
Cesana, M.1
Cacchiarelli, D.2
Legnini, I.3
Santini, T.4
Sthandier, O.5
Chinappi, M.6
-
8
-
-
84874583945
-
Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity
-
Fang, L., Du, W.W., Yang, X., Chen, K., Ghanekar, A., Levy, G., et al. Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity. FASEB Journal 27 (2013), 907–919.
-
(2013)
FASEB Journal
, vol.27
, pp. 907-919
-
-
Fang, L.1
Du, W.W.2
Yang, X.3
Chen, K.4
Ghanekar, A.5
Levy, G.6
-
9
-
-
84901838697
-
Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance
-
Denzler, R., Agarwal, V., Stefano, J., Bartel, D.P., Stoffel, M., Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. Molecular Cell 54 (2014), 766–776.
-
(2014)
Molecular Cell
, vol.54
, pp. 766-776
-
-
Denzler, R.1
Agarwal, V.2
Stefano, J.3
Bartel, D.P.4
Stoffel, M.5
-
10
-
-
84922418997
-
Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition
-
Bosson, A.D., Zamudio, J.R., Sharp, P.A., Endogenous miRNA and target concentrations determine susceptibility to potential ceRNA competition. Molecular Cell 56 (2014), 347–359.
-
(2014)
Molecular Cell
, vol.56
, pp. 347-359
-
-
Bosson, A.D.1
Zamudio, J.R.2
Sharp, P.A.3
-
11
-
-
84995467719
-
Impact of MicroRNA levels, target-site complementarity, and cooperativity on competing endogenous RNA-regulated gene expression
-
Denzler, R., McGeary, S.E., Title, A.C., Agarwal, V., Bartel, D.P., Stoffel, M., Impact of MicroRNA levels, target-site complementarity, and cooperativity on competing endogenous RNA-regulated gene expression. Molecular Cell 64 (2016), 565–579.
-
(2016)
Molecular Cell
, vol.64
, pp. 565-579
-
-
Denzler, R.1
McGeary, S.E.2
Title, A.C.3
Agarwal, V.4
Bartel, D.P.5
Stoffel, M.6
-
12
-
-
84875372911
-
Natural RNA circles function as efficient microRNA sponges
-
Hansen, T.B., Jensen, T.I., Clausen, B.H., Bramsen, J.B., Finsen, B., Damgaard, C.K., et al. Natural RNA circles function as efficient microRNA sponges. Nature 495 (2013), 384–388.
-
(2013)
Nature
, vol.495
, pp. 384-388
-
-
Hansen, T.B.1
Jensen, T.I.2
Clausen, B.H.3
Bramsen, J.B.4
Finsen, B.5
Damgaard, C.K.6
-
13
-
-
84875369248
-
Circular RNAs are a large class of animal RNAs with regulatory potency
-
Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., et al. Circular RNAs are a large class of animal RNAs with regulatory potency. Nature 495 (2013), 333–338.
-
(2013)
Nature
, vol.495
, pp. 333-338
-
-
Memczak, S.1
Jens, M.2
Elefsinioti, A.3
Torti, F.4
Krueger, J.5
Rybak, A.6
-
14
-
-
84956906428
-
Expanded identification and characterization of mammalian circular RNAs
-
Guo, J.U., Agarwal, V., Guo, H., Bartel, D.P., Expanded identification and characterization of mammalian circular RNAs. Genome Biology, 15, 2014, 409.
-
(2014)
Genome Biology
, vol.15
, pp. 409
-
-
Guo, J.U.1
Agarwal, V.2
Guo, H.3
Bartel, D.P.4
-
15
-
-
65249093130
-
miR-375 maintains normal pancreatic alpha- and beta-cell mass
-
Poy, M.N., Hausser, J., Trajkovski, M., Braun, M., Collins, S., Rorsman, P., et al. miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proceedings of the National Academy of Sciences of the United States of America 106 (2009), 5813–5818.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 5813-5818
-
-
Poy, M.N.1
Hausser, J.2
Trajkovski, M.3
Braun, M.4
Collins, S.5
Rorsman, P.6
-
16
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S.E., Hull, R.L., Utzschneider, K.M., Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444 (2006), 840–846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
17
-
-
36248978699
-
MicroRNA expression is required for pancreatic islet cell genesis in the mouse
-
Lynn, F.C., Skewes-Cox, P., Kosaka, Y., McManus, M.T., Harfe, B.D., German, M.S., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes 56 (2007), 2938–2945.
-
(2007)
Diabetes
, vol.56
, pp. 2938-2945
-
-
Lynn, F.C.1
Skewes-Cox, P.2
Kosaka, Y.3
McManus, M.T.4
Harfe, B.D.5
German, M.S.6
-
18
-
-
84876530204
-
Dicer1 is required to repress neuronal fate during endocrine cell maturation
-
Kanji, M.S., Martin, M.G., Bhushan, A., Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes 62 (2013), 1602–1611.
-
(2013)
Diabetes
, vol.62
, pp. 1602-1611
-
-
Kanji, M.S.1
Martin, M.G.2
Bhushan, A.3
-
19
-
-
84455161954
-
Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus
-
Kalis, M., Bolmeson, C., Esguerra, J.L., Gupta, S., Edlund, A., Tormo-Badia, N., et al. Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus. PLoS One, 6, 2011, e29166.
-
(2011)
PLoS One
, vol.6
-
-
Kalis, M.1
Bolmeson, C.2
Esguerra, J.L.3
Gupta, S.4
Edlund, A.5
Tormo-Badia, N.6
-
20
-
-
84867028085
-
Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism
-
Mandelbaum, A.D., Melkman-Zehavi, T., Oren, R., Kredo-Russo, S., Nir, T., Dor, Y., et al. Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism. Experimental Diabetes Research, 2012, 2012, 470302.
-
(2012)
Experimental Diabetes Research
, vol.2012
-
-
Mandelbaum, A.D.1
Melkman-Zehavi, T.2
Oren, R.3
Kredo-Russo, S.4
Nir, T.5
Dor, Y.6
-
21
-
-
84936123498
-
DICER inactivation identifies pancreatic β-cell “disallowed” genes targeted by microRNAs
-
Martinez-Sanchez, A., Nguyen-Tu, M.-S., Rutter, G.A., DICER inactivation identifies pancreatic β-cell “disallowed” genes targeted by microRNAs. Molecular Endocrinology 29 (2015), 1067–1079.
-
(2015)
Molecular Endocrinology
, vol.29
, pp. 1067-1079
-
-
Martinez-Sanchez, A.1
Nguyen-Tu, M.-S.2
Rutter, G.A.3
-
22
-
-
33751073710
-
Denoising feedback loops by thresholding – a new role for microRNAs
-
Cohen, S.M., Brennecke, J., Stark, A., Denoising feedback loops by thresholding – a new role for microRNAs. Genes & Development 20 (2006), 2769–2772.
-
(2006)
Genes & Development
, vol.20
, pp. 2769-2772
-
-
Cohen, S.M.1
Brennecke, J.2
Stark, A.3
-
23
-
-
77953429949
-
Identification of genes selectively disallowed in the pancreatic islet
-
Pullen, T.J., Khan, A.M., Barton, G., Butcher, S.A., Sun, G., Rutter, G.A., Identification of genes selectively disallowed in the pancreatic islet. Islets 2 (2010), 89–95.
-
(2010)
Islets
, vol.2
, pp. 89-95
-
-
Pullen, T.J.1
Khan, A.M.2
Barton, G.3
Butcher, S.A.4
Sun, G.5
Rutter, G.A.6
-
24
-
-
0033431775
-
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells
-
Ishihara, H., Wang, H., Drewes, L.R., Wollheim, C.B., Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells. Journal of Clinical Investigation 104 (1999), 1621–1629.
-
(1999)
Journal of Clinical Investigation
, vol.104
, pp. 1621-1629
-
-
Ishihara, H.1
Wang, H.2
Drewes, L.R.3
Wollheim, C.B.4
-
25
-
-
1542271011
-
Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells
-
Kataoka, K., Shioda, S., Ando, K., Sakagami, K., Handa, H., Yasuda, K., Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells. Journal of Molecular Endocrinology 32 (2004), 9–20.
-
(2004)
Journal of Molecular Endocrinology
, vol.32
, pp. 9-20
-
-
Kataoka, K.1
Shioda, S.2
Ando, K.3
Sakagami, K.4
Handa, H.5
Yasuda, K.6
-
26
-
-
80054991835
-
PDGF signalling controls age-dependent proliferation in pancreatic β-cells
-
Chen, H., Gu, X., Liu, Y., Wang, J., Wirt, S.E., Bottino, R., et al. PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature 478 (2011), 349–355.
-
(2011)
Nature
, vol.478
, pp. 349-355
-
-
Chen, H.1
Gu, X.2
Liu, Y.3
Wang, J.4
Wirt, S.E.5
Bottino, R.6
-
27
-
-
85015325896
-
Ornithine aminotransferase, an important glutamate-metabolizing enzyme at the crossroads of multiple metabolic pathways
-
pii: E18
-
Ginguay, A., Cynober, L., Curis, E., Nicolis, I., Ornithine aminotransferase, an important glutamate-metabolizing enzyme at the crossroads of multiple metabolic pathways. Biology (Basel), 6(1), 2017 Mar 7, 10.3390/biology6010018 pii: E18.
-
(2017)
Biology (Basel)
, vol.6
, Issue.1
-
-
Ginguay, A.1
Cynober, L.2
Curis, E.3
Nicolis, I.4
-
28
-
-
33748367666
-
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins
-
Sitar, T., Popowicz, G.M., Siwanowicz, I., Huber, R., Holak, T.A., Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proceedings of the National Academy of Sciences of the United States of America 103 (2006), 13028–13033.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 13028-13033
-
-
Sitar, T.1
Popowicz, G.M.2
Siwanowicz, I.3
Huber, R.4
Holak, T.A.5
-
29
-
-
84891856209
-
Epigenetic regulation of the DLK1-MEG3 MicroRNA cluster in human type 2 diabetic islets
-
Kameswaran, V., Bramswig, N.C., McKenna, L.B., Penn, M., Schug, J., Hand, N.J., et al. Epigenetic regulation of the DLK1-MEG3 MicroRNA cluster in human type 2 diabetic islets. Cell Metabolism 19 (2014), 135–145.
-
(2014)
Cell Metabolism
, vol.19
, pp. 135-145
-
-
Kameswaran, V.1
Bramswig, N.C.2
McKenna, L.B.3
Penn, M.4
Schug, J.5
Hand, N.J.6
-
30
-
-
85000434635
-
Identification and characterization of microRNAs associated with human β-cell loss in a mouse model
-
Roat, R., Hossain, M.M., Christopherson, J., Free, C., Jain, S., Guay, C., et al. Identification and characterization of microRNAs associated with human β-cell loss in a mouse model. American Journal of Transplantation 17 (2017), 992–1007.
-
(2017)
American Journal of Transplantation
, vol.17
, pp. 992-1007
-
-
Roat, R.1
Hossain, M.M.2
Christopherson, J.3
Free, C.4
Jain, S.5
Guay, C.6
-
31
-
-
84891867862
-
Argonaute2 mediates compensatory expansion of the pancreatic β cell
-
Tattikota, S.G., Rathjen, T., McAnulty, S.J., Wessels, H.-H., Akerman, I., van de Bunt, M., et al. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Cell Metabolism 19 (2014), 122–134.
-
(2014)
Cell Metabolism
, vol.19
, pp. 122-134
-
-
Tattikota, S.G.1
Rathjen, T.2
McAnulty, S.J.3
Wessels, H.-H.4
Akerman, I.5
van de Bunt, M.6
-
32
-
-
84877614776
-
Argonaute2 regulates the pancreatic β-cell secretome
-
Tattikota, S.G., Sury, M.D., Rathjen, T., Wessels, H.-H., Pandey, A.K., You, X., et al. Argonaute2 regulates the pancreatic β-cell secretome. Molecular & Cellular Proteomics 12 (2013), 1214–1225.
-
(2013)
Molecular & Cellular Proteomics
, vol.12
, pp. 1214-1225
-
-
Tattikota, S.G.1
Sury, M.D.2
Rathjen, T.3
Wessels, H.-H.4
Pandey, A.K.5
You, X.6
-
33
-
-
84890124194
-
Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes
-
Nesca, V., Guay, C., Jacovetti, C., Menoud, V., Peyot, M.-L., Laybutt, D., et al. Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes. Diabetologia 56:10 (2013), 2203–2212.
-
(2013)
Diabetologia
, vol.56
, Issue.10
, pp. 2203-2212
-
-
Nesca, V.1
Guay, C.2
Jacovetti, C.3
Menoud, V.4
Peyot, M.-L.5
Laybutt, D.6
-
34
-
-
70349866341
-
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice
-
Zhao, E., Keller, M.P., Rabaglia, M.E., Oler, A.T., Stapleton, D.S., Schueler, K.L., et al. Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mammalian Genome 20 (2009), 476–485.
-
(2009)
Mammalian Genome
, vol.20
, pp. 476-485
-
-
Zhao, E.1
Keller, M.P.2
Rabaglia, M.E.3
Oler, A.T.4
Stapleton, D.S.5
Schueler, K.L.6
-
35
-
-
84863228519
-
Changes in MicroRNA expression contribute to pancreatic b-cell dysfunction in prediabetic NOD mice
-
Roggli, E., Gattesco, S., Caille, D., Briet, C., Boitard, C., Meda, P., et al. Changes in MicroRNA expression contribute to pancreatic b-cell dysfunction in prediabetic NOD mice. Diabetes 61:7 (2012), 1742–1751.
-
(2012)
Diabetes
, vol.61
, Issue.7
, pp. 1742-1751
-
-
Roggli, E.1
Gattesco, S.2
Caille, D.3
Briet, C.4
Boitard, C.5
Meda, P.6
-
36
-
-
85007307434
-
MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149 5p regulate the expression of proapoptotic BH3 only proteins DP5 and PUMA in human pancreatic β-cells
-
Grieco, F.A., Sebastiani, G., Juan-Mateu, J., Villate, O., Marroqui, L., Ladrière, L., et al. MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149 5p regulate the expression of proapoptotic BH3 only proteins DP5 and PUMA in human pancreatic β-cells. Diabetes 66 (2017), 100–112.
-
(2017)
Diabetes
, vol.66
, pp. 100-112
-
-
Grieco, F.A.1
Sebastiani, G.2
Juan-Mateu, J.3
Villate, O.4
Marroqui, L.5
Ladrière, L.6
-
37
-
-
84870717296
-
Inflammation-mediated regulation of MicroRNA expression in transplanted pancreatic islets
-
Bravo-Egana, V., Rosero, S., Klein, D., Jiang, Z., Vargas, N., Tsinoremas, N., et al. Inflammation-mediated regulation of MicroRNA expression in transplanted pancreatic islets. Journal of Transplantation 2012 (2012), 1–15.
-
(2012)
Journal of Transplantation
, vol.2012
, pp. 1-15
-
-
Bravo-Egana, V.1
Rosero, S.2
Klein, D.3
Jiang, Z.4
Vargas, N.5
Tsinoremas, N.6
-
38
-
-
84891043328
-
Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion
-
Locke, J.M., Da Silva Xavier, G., Dawe, H.R., Rutter, G.A., Harries, L.W., Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion. Diabetologia 57 (2014), 122–128.
-
(2014)
Diabetologia
, vol.57
, pp. 122-128
-
-
Locke, J.M.1
Da Silva Xavier, G.2
Dawe, H.R.3
Rutter, G.A.4
Harries, L.W.5
-
39
-
-
77951190661
-
Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression
-
Git, A., Dvinge, H., Salmon-Divon, M., Osborne, M., Kutter, C., Hadfield, J., et al. Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression. RNA 16 (2010), 991–1006.
-
(2010)
RNA
, vol.16
, pp. 991-1006
-
-
Git, A.1
Dvinge, H.2
Salmon-Divon, M.3
Osborne, M.4
Kutter, C.5
Hadfield, J.6
-
40
-
-
84926291228
-
Small RNA sequencing for profiling microRNAs in long-term preserved formalin-fixed and paraffin-embedded non-small cell lung cancer tumor specimens
-
Buitrago, D.H., Patnaik, S.K., Kadota, K., Kannisto, E., Jone, D.R., Adusumilli, P.S., Small RNA sequencing for profiling microRNAs in long-term preserved formalin-fixed and paraffin-embedded non-small cell lung cancer tumor specimens. PLoS One 10 (2015), 1–12.
-
(2015)
PLoS One
, vol.10
, pp. 1-12
-
-
Buitrago, D.H.1
Patnaik, S.K.2
Kadota, K.3
Kannisto, E.4
Jone, D.R.5
Adusumilli, P.S.6
-
41
-
-
79952259862
-
miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors
-
Melkman-Zehavi, T., Oren, R., Kredo-Russo, S., Shapira, T., Mandelbaum, A.D., Rivkin, N., et al. miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors. The EMBO Journal 30 (2011), 835–845.
-
(2011)
The EMBO Journal
, vol.30
, pp. 835-845
-
-
Melkman-Zehavi, T.1
Oren, R.2
Kredo-Russo, S.3
Shapira, T.4
Mandelbaum, A.D.5
Rivkin, N.6
-
42
-
-
85011416868
-
miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway
-
Zeng, X., Huang, C., Senavirathna, L., Wang, P., Liu, L., miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway. BMC Cell Biology, 18, 2017, 9.
-
(2017)
BMC Cell Biology
, vol.18
, pp. 9
-
-
Zeng, X.1
Huang, C.2
Senavirathna, L.3
Wang, P.4
Liu, L.5
-
43
-
-
78650902669
-
Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects
-
Bolmeson, C., Esguerra, J.L., Salehi, A., Speidel, D., Eliasson, L., Cilio, C.M., Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects. Biochemical and Biophysical Research 404 (2011), 16–22.
-
(2011)
Biochemical and Biophysical Research
, vol.404
, pp. 16-22
-
-
Bolmeson, C.1
Esguerra, J.L.2
Salehi, A.3
Speidel, D.4
Eliasson, L.5
Cilio, C.M.6
-
45
-
-
80053481600
-
The Lin28/let-7 axis regulates glucose metabolism
-
Zhu, H., Shyh-Chang, N., Segrè, A.V., Shinoda, G., Shah, S.P., Einhorn, W.S., et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 147 (2011), 81–94.
-
(2011)
Cell
, vol.147
, pp. 81-94
-
-
Zhu, H.1
Shyh-Chang, N.2
Segrè, A.V.3
Shinoda, G.4
Shah, S.P.5
Einhorn, W.S.6
-
46
-
-
58149350343
-
miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells
-
Ouaamari, E.I., Baroukh, N., Martens, G.A., Lebrun, P., Pipeleers, D., van Obberghen, E., miR-375 targets 3′-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes 57 (2008), 2708–2717.
-
(2008)
Diabetes
, vol.57
, pp. 2708-2717
-
-
Ouaamari, E.I.1
Baroukh, N.2
Martens, G.A.3
Lebrun, P.4
Pipeleers, D.5
van Obberghen, E.6
-
47
-
-
84942985712
-
miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development
-
Latreille, M., Herrmanns, K., Renwick, N., Tuschl, T., Malecki, M.T., McCarthy, M.I., et al. miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development. Journal of Molecular Medicine (Berlin) 93 (2015), 1159–1169.
-
(2015)
Journal of Molecular Medicine (Berlin)
, vol.93
, pp. 1159-1169
-
-
Latreille, M.1
Herrmanns, K.2
Renwick, N.3
Tuschl, T.4
Malecki, M.T.5
McCarthy, M.I.6
-
48
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129 (2007), 1401–1414.
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
Sewer, A.4
Iovino, N.5
Aravin, A.6
-
49
-
-
85015862205
-
Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility
-
Ahmed, K., LaPierre, M.P., Gasser, E., Denzler, R., Yang, Y., Rülicke, T., et al. Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility. Journal of Clinical Investigation 127 (2017), 1061–1074.
-
(2017)
Journal of Clinical Investigation
, vol.127
, pp. 1061-1074
-
-
Ahmed, K.1
LaPierre, M.P.2
Gasser, E.3
Denzler, R.4
Yang, Y.5
Rülicke, T.6
-
50
-
-
84938256320
-
The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells
-
Xu, H., Guo, S., Li, W., Yu, P., The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells. Scientific Reports, 5, 2015, 12453.
-
(2015)
Scientific Reports
, vol.5
, pp. 12453
-
-
Xu, H.1
Guo, S.2
Li, W.3
Yu, P.4
-
51
-
-
84900797916
-
MicroRNA-7a regulates pancreatic β cell function
-
Latreille, M., Hausser, J., Stützer, I., Zhang, Q., Hastoy, B., Gargani, S., et al. MicroRNA-7a regulates pancreatic β cell function. Journal of Clinical Investigation 124 (2014), 2722–2735.
-
(2014)
Journal of Clinical Investigation
, vol.124
, pp. 2722-2735
-
-
Latreille, M.1
Hausser, J.2
Stützer, I.3
Zhang, Q.4
Hastoy, B.5
Gargani, S.6
-
52
-
-
79954555856
-
Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat
-
Esguerra, J.L., Bolmeson, C., Cilio, C.M., Eliasson, L., Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat. PLoS One, 6, 2011, e18613.
-
(2011)
PLoS One
, vol.6
-
-
Esguerra, J.L.1
Bolmeson, C.2
Cilio, C.M.3
Eliasson, L.4
-
53
-
-
84864305807
-
Pancreas enriched miRNA refines endocrine cell differentiation
-
Kredo-Russo, S., Mandelbaum, A.D., Ness, A., Alon, I., Lennox, K.A., Behlke, M.A., et al. Pancreas enriched miRNA refines endocrine cell differentiation. Development 139 (2012), 3021–3031.
-
(2012)
Development
, vol.139
, pp. 3021-3031
-
-
Kredo-Russo, S.1
Mandelbaum, A.D.2
Ness, A.3
Alon, I.4
Lennox, K.A.5
Behlke, M.A.6
-
54
-
-
84923251398
-
Characterization of miR-218/322-Stxbp1 pathway in the process of insulin secretion
-
Lang, H., Ai, Z., You, Z., Wan, Y., Guo, W., Xiao, J., et al. Characterization of miR-218/322-Stxbp1 pathway in the process of insulin secretion. Journal of Molecular Endocrinology 54 (2015), 65–73.
-
(2015)
Journal of Molecular Endocrinology
, vol.54
, pp. 65-73
-
-
Lang, H.1
Ai, Z.2
You, Z.3
Wan, Y.4
Guo, W.5
Xiao, J.6
-
55
-
-
84878618788
-
Syntaxin-1a is a direct target of miR-29a in insulin-producing β-cells. Syntaxin-1a is a direct target of miR-29a in insulin-producing β-cells
-
Bagge, A., Dahmcke, C.M., Dalgaard, L.T., Syntaxin-1a is a direct target of miR-29a in insulin-producing β-cells. Syntaxin-1a is a direct target of miR-29a in insulin-producing β-cells. Hormone and Metabolic Research 45 (2013), 463–466.
-
(2013)
Hormone and Metabolic Research
, vol.45
, pp. 463-466
-
-
Bagge, A.1
Dahmcke, C.M.2
Dalgaard, L.T.3
-
56
-
-
33748749597
-
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells
-
Plaisance, V., Abderrahmani, A., Perret-Menoud, V., Jacquemin, P., Lemaigre, F., Regazzi, R., MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. Journal of Biological Chemistry 281 (2006), 26932–26942.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 26932-26942
-
-
Plaisance, V.1
Abderrahmani, A.2
Perret-Menoud, V.3
Jacquemin, P.4
Lemaigre, F.5
Regazzi, R.6
-
57
-
-
0035125001
-
β-Cell dysfunction and failure in type 2 diabetes: potential mechanisms
-
Porte, D. Jr., Kahn, S.E., β-Cell dysfunction and failure in type 2 diabetes: potential mechanisms. Diabetes 50:Suppl. 1 (2001), S160–S163.
-
(2001)
Diabetes
, vol.50
, pp. S160-S163
-
-
Porte, D.1
Kahn, S.E.2
-
58
-
-
84983740826
-
MiR-206 is expressed in pancreatic islets and regulates glucokinase activity
-
Vinod, M., Patankar, J.V., Sachdev, V., Frank, S., Graier, W.F., Kratky, D., et al. MiR-206 is expressed in pancreatic islets and regulates glucokinase activity. American Journal of Physiology Endocrinology and Metabolism 311 (2016), E175–E185.
-
(2016)
American Journal of Physiology Endocrinology and Metabolism
, vol.311
, pp. E175-E185
-
-
Vinod, M.1
Patankar, J.V.2
Sachdev, V.3
Frank, S.4
Graier, W.F.5
Kratky, D.6
-
59
-
-
84939825167
-
miR-184 regulates pancreatic β-cell function according to glucose metabolism
-
Tattikota, S.G., Rathjen, T., Hausser, J., Khedkar, A., Kabra, U.D., Pandey, V., et al. miR-184 regulates pancreatic β-cell function according to glucose metabolism. Journal of Biological Chemistry 290 (2015), 20284–20294.
-
(2015)
Journal of Biological Chemistry
, vol.290
, pp. 20284-20294
-
-
Tattikota, S.G.1
Rathjen, T.2
Hausser, J.3
Khedkar, A.4
Kabra, U.D.5
Pandey, V.6
-
60
-
-
84883116249
-
miR-25 and miR-92a regulate insulin I biosynthesis in rats
-
Setyowati Karolina, D., Sepramaniam, S., Tan, H.Z., Armugam, A., Jeyaseelan, K., miR-25 and miR-92a regulate insulin I biosynthesis in rats. RNA Biology 10 (2013), 1365–1378.
-
(2013)
RNA Biology
, vol.10
, pp. 1365-1378
-
-
Setyowati Karolina, D.1
Sepramaniam, S.2
Tan, H.Z.3
Armugam, A.4
Jeyaseelan, K.5
-
61
-
-
84887363120
-
MicroRNA-24/MODY gene regulatory pathway mediates pancreatic β-cell dysfunction
-
Zhu, Y., You, W., Wang, H., Li, Y., Qiao, N., Shi, Y., et al. MicroRNA-24/MODY gene regulatory pathway mediates pancreatic β-cell dysfunction. Diabetes 62 (2013), 3194–3206.
-
(2013)
Diabetes
, vol.62
, pp. 3194-3206
-
-
Zhu, Y.1
You, W.2
Wang, H.3
Li, Y.4
Qiao, N.5
Shi, Y.6
-
62
-
-
84876484626
-
miRNA-30a-5p-mediated silencing of Beta2/NeuroD expression is an important initial event of glucotoxicity-induced beta cell dysfunction in rodent models
-
Kim, J.W., You, Y.H., Jung, S., Suh-Kim, H., Lee, I.K., Cho, J.H., et al. miRNA-30a-5p-mediated silencing of Beta2/NeuroD expression is an important initial event of glucotoxicity-induced beta cell dysfunction in rodent models. Diabetologia 56 (2013), 847–855.
-
(2013)
Diabetologia
, vol.56
, pp. 847-855
-
-
Kim, J.W.1
You, Y.H.2
Jung, S.3
Suh-Kim, H.4
Lee, I.K.5
Cho, J.H.6
-
63
-
-
84883793279
-
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
-
Xu, G., Chen, J., Jing, G., Shalev, A., Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. Nature Medicine 19 (2013), 1141–1146.
-
(2013)
Nature Medicine
, vol.19
, pp. 1141-1146
-
-
Xu, G.1
Chen, J.2
Jing, G.3
Shalev, A.4
-
64
-
-
34547126004
-
MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines
-
Baroukh, N., Ravier, M.A., Loder, M.K., Hill, E.V., Bounacer, A., Scharfmann, R., et al. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. Journal of Biological Chemistry 282 (2007), 19575–19588.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 19575-19588
-
-
Baroukh, N.1
Ravier, M.A.2
Loder, M.K.3
Hill, E.V.4
Bounacer, A.5
Scharfmann, R.6
-
65
-
-
9144270691
-
A pancreatic islet-specific microRNA regulates insulin secretion
-
Poy, M.N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., Macdonald, P.E., et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432 (2004), 226–230.
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
Macdonald, P.E.6
-
66
-
-
84901942076
-
Altering β-cell number through stable alteration of miR-21 and miR-34a expression
-
Backe, M.B., Novotny, G.W., Christensen, D.P., Grunnet, L.G., Mandrup-Poulsen, T., Altering β-cell number through stable alteration of miR-21 and miR-34a expression. Islets, 6, 2014, e27754.
-
(2014)
Islets
, vol.6
-
-
Backe, M.B.1
Novotny, G.W.2
Christensen, D.P.3
Grunnet, L.G.4
Mandrup-Poulsen, T.5
-
67
-
-
85008222752
-
MicroRNAs 106b and 222 improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation
-
Tsukita, S., Yamada, T., Takahashi, K., Munakata, Y., Hosaka, S., Takahashi, H., et al. MicroRNAs 106b and 222 improve hyperglycemia in a mouse model of insulin-deficient diabetes via pancreatic β-cell proliferation. EBioMedicine 15 (2017), 163–172.
-
(2017)
EBioMedicine
, vol.15
, pp. 163-172
-
-
Tsukita, S.1
Yamada, T.2
Takahashi, K.3
Munakata, Y.4
Hosaka, S.5
Takahashi, H.6
-
68
-
-
84960373350
-
MiR-126 suppresses the glucose-stimulated proliferation via IRS-2 in INS-1 β cells
-
Tao, H., Wang, M.M., Zhang, M., Zhang, S.P., Wang, C.H., Yuan, W.J., et al. MiR-126 suppresses the glucose-stimulated proliferation via IRS-2 in INS-1 β cells. PLoS One, 11, 2016, e0149954.
-
(2016)
PLoS One
, vol.11
-
-
Tao, H.1
Wang, M.M.2
Zhang, M.3
Zhang, S.P.4
Wang, C.H.5
Yuan, W.J.6
-
69
-
-
84942311924
-
Glucose-induced microRNA-17 promotes pancreatic beta cell proliferation through down-regulation of Menin
-
Lu, Y., Fei, X.Q., Yang, S.F., Xu, B.K., Li, Y.Y., Glucose-induced microRNA-17 promotes pancreatic beta cell proliferation through down-regulation of Menin. European Review for Medical and Pharmacological Sciences 19 (2015), 624–629.
-
(2015)
European Review for Medical and Pharmacological Sciences
, vol.19
, pp. 624-629
-
-
Lu, Y.1
Fei, X.Q.2
Yang, S.F.3
Xu, B.K.4
Li, Y.Y.5
-
70
-
-
84930513535
-
Contribution of intronic miR-338-3p and its hosting gene AATK to compensatory β-cell mass expansion
-
Jacovetti, C., Jimenez, V., Ayuso, E., Laybutt, R., Peyot, M.L., Prentki, M., et al. Contribution of intronic miR-338-3p and its hosting gene AATK to compensatory β-cell mass expansion. Molecular Endocrinology 29 (2015), 693–702.
-
(2015)
Molecular Endocrinology
, vol.29
, pp. 693-702
-
-
Jacovetti, C.1
Jimenez, V.2
Ayuso, E.3
Laybutt, R.4
Peyot, M.L.5
Prentki, M.6
-
71
-
-
33644749322
-
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities
-
Cnop, M., Welsh, N., Jonas, J.C., Jörns, A., Lenzen, S., Eizirik, D.L., Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54:Suppl. 2 (2005), S97–S107.
-
(2005)
Diabetes
, vol.54
, pp. S97-S107
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jörns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
72
-
-
84902352296
-
β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment
-
Halban, P.A., Polonsky, K.S., Bowden, D.W., Hawkins, M.A., Ling, C., Mather, K.J., et al. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Journal of Clinical Endocrinology & Metabolism 99 (2014), 1983–1992.
-
(2014)
Journal of Clinical Endocrinology & Metabolism
, vol.99
, pp. 1983-1992
-
-
Halban, P.A.1
Polonsky, K.S.2
Bowden, D.W.3
Hawkins, M.A.4
Ling, C.5
Mather, K.J.6
-
73
-
-
77955507555
-
miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1
-
Schickel, R., Park, S.M., Murmann, A.E., Peter, M.E., miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1. Molecular Cell 38 (2010), 908–915.
-
(2010)
Molecular Cell
, vol.38
, pp. 908-915
-
-
Schickel, R.1
Park, S.M.2
Murmann, A.E.3
Peter, M.E.4
-
74
-
-
84919820315
-
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis
-
Filios, S.R., Xu, G., Chen, J., Hong, K., Jing, G., Shalev, A., MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis. J Biol Chem 289 (2014), 36275–36283.
-
(2014)
J Biol Chem
, vol.289
, pp. 36275-36283
-
-
Filios, S.R.1
Xu, G.2
Chen, J.3
Hong, K.4
Jing, G.5
Shalev, A.6
-
75
-
-
84995595336
-
Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis
-
Wang, Y., Li, D., Luo, J., Tian, G., Zhao, L.Y., Liao, D., Intrinsic cellular signaling mechanisms determine the sensitivity of cancer cells to virus-induced apoptosis. Scientific Reports, 6, 2016, 37213.
-
(2016)
Scientific Reports
, vol.6
-
-
Wang, Y.1
Li, D.2
Luo, J.3
Tian, G.4
Zhao, L.Y.5
Liao, D.6
-
76
-
-
84943775812
-
p38/p53/miR-200a-3p feedback loop promotes oxidative stress-mediated liver cell death
-
Xiao, Y., Yan, W., Lu, L., Wang, Y., Lu, W., Cao, Y., et al. p38/p53/miR-200a-3p feedback loop promotes oxidative stress-mediated liver cell death. Cell Cycle 14 (2015), 1548–1558.
-
(2015)
Cell Cycle
, vol.14
, pp. 1548-1558
-
-
Xiao, Y.1
Yan, W.2
Lu, L.3
Wang, Y.4
Lu, W.5
Cao, Y.6
-
77
-
-
84930751975
-
The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes
-
Belgardt, B.F., Ahmed, K., Spranger, M., Latreille, M., Denzler, R., Kondratiuk, N., et al. The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. Nature Medicine 21 (2015), 619–627.
-
(2015)
Nature Medicine
, vol.21
, pp. 619-627
-
-
Belgardt, B.F.1
Ahmed, K.2
Spranger, M.3
Latreille, M.4
Denzler, R.5
Kondratiuk, N.6
-
78
-
-
84965110675
-
Cytokines regulate β-cell thioredoxin-interacting protein (TXNIP) via distinct mechanisms and pathways
-
Hong, K., Xu, G., Grayson, T.B., Shalev, A., Cytokines regulate β-cell thioredoxin-interacting protein (TXNIP) via distinct mechanisms and pathways. Journal of Biological Chemistry 291 (2016), 8428–8439.
-
(2016)
Journal of Biological Chemistry
, vol.291
, pp. 8428-8439
-
-
Hong, K.1
Xu, G.2
Grayson, T.B.3
Shalev, A.4
-
79
-
-
84864682160
-
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
-
Lerner, A.G., Upton, J.P., Praveen, P.V., Ghosh, R., Nakagawa, Y., Igbaria, A., et al. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism 16 (2012), 250–264.
-
(2012)
Cell Metabolism
, vol.16
, pp. 250-264
-
-
Lerner, A.G.1
Upton, J.P.2
Praveen, P.V.3
Ghosh, R.4
Nakagawa, Y.5
Igbaria, A.6
-
80
-
-
84948464637
-
miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction
-
Zheng, Y., Wang, Z., Tu, Y., Shen, H., Dai, Z., Lin, J., et al. miR-101a and miR-30b contribute to inflammatory cytokine-mediated β-cell dysfunction. Laboratory Investigation 95 (2015), 1387–1397.
-
(2015)
Laboratory Investigation
, vol.95
, pp. 1387-1397
-
-
Zheng, Y.1
Wang, Z.2
Tu, Y.3
Shen, H.4
Dai, Z.5
Lin, J.6
-
81
-
-
84992696188
-
MicroRNA-19a-3p enhances the proliferation and insulin secretion, while it inhibits the apoptosis of pancreatic β cells via the inhibition of SOCS3
-
Li, Y., Luo, T., Wang, L., Wu, J., Guo, S., MicroRNA-19a-3p enhances the proliferation and insulin secretion, while it inhibits the apoptosis of pancreatic β cells via the inhibition of SOCS3. International Journal of Molecular Medicine 38 (2016), 1515–1524.
-
(2016)
International Journal of Molecular Medicine
, vol.38
, pp. 1515-1524
-
-
Li, Y.1
Luo, T.2
Wang, L.3
Wu, J.4
Guo, S.5
-
82
-
-
84939131576
-
Differentially expressed MicroRNA-483 confers distinct functions in pancreatic β- and α-cells
-
Mohan, R., Mao, Y., Zhang, S., Zhang, Y.W., Xu, C.R., Gradwohl, G., et al. Differentially expressed MicroRNA-483 confers distinct functions in pancreatic β- and α-cells. Journal of Biological Chemistry 290 (2015), 19955–19966.
-
(2015)
Journal of Biological Chemistry
, vol.290
, pp. 19955-19966
-
-
Mohan, R.1
Mao, Y.2
Zhang, S.3
Zhang, Y.W.4
Xu, C.R.5
Gradwohl, G.6
-
83
-
-
84922738648
-
MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes
-
Bao, L., Fu, X., Si, M., Wang, Y., Ma, R., Ren, X., et al. MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. PLoS One, 10, 2015, e0116067.
-
(2015)
PLoS One
, vol.10
-
-
Bao, L.1
Fu, X.2
Si, M.3
Wang, Y.4
Ma, R.5
Ren, X.6
-
84
-
-
70349566593
-
Diabetes mellitus: a “thrifty” genotype rendered detrimental by “progress”?
-
Neel, J.V., Diabetes mellitus: a “thrifty” genotype rendered detrimental by “progress”?. American Journal of Human Genetics 14 (1962), 353–362.
-
(1962)
American Journal of Human Genetics
, vol.14
, pp. 353-362
-
-
Neel, J.V.1
-
85
-
-
33745626115
-
Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil)
-
Shafrir, E., Ziv, E., Kalman, R., Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil). ILAR Journal 47 (2006), 212–224.
-
(2006)
ILAR Journal
, vol.47
, pp. 212-224
-
-
Shafrir, E.1
Ziv, E.2
Kalman, R.3
-
86
-
-
48749122914
-
Circulating microRNAs as stable blood-based markers for cancer detection
-
Mitchell, P.S., Parkin, R.K., Kroh, E.M., Fritz, B.R., Wyman, S.K., Pogosova-Agadjanyan, E.L., et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proceedings of the National Academy of Sciences of the United States of America 105 (2008), 10513–10518.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 10513-10518
-
-
Mitchell, P.S.1
Parkin, R.K.2
Kroh, E.M.3
Fritz, B.R.4
Wyman, S.K.5
Pogosova-Agadjanyan, E.L.6
-
87
-
-
53349177819
-
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
-
Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Research 18 (2008), 997–1006.
-
(2008)
Cell Research
, vol.18
, pp. 997-1006
-
-
Chen, X.1
Ba, Y.2
Ma, L.3
Cai, X.4
Yin, Y.5
Wang, K.6
-
88
-
-
77449127999
-
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
-
Zernecke, A., Bidzhekov, K., Noels, H., Shagdarsuren, E., Gan, L., Denecke, B., et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Science Signalling, 2, 2009, ra81.
-
(2009)
Science Signalling
, vol.2
, pp. ra81
-
-
Zernecke, A.1
Bidzhekov, K.2
Noels, H.3
Shagdarsuren, E.4
Gan, L.5
Denecke, B.6
-
89
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi, H., Ekstrom, K., Bossios, A., Sjostrand, M., Lee, J.J., Lotvall, J.O., Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nature Cell Biology 9 (2007), 654–659.
-
(2007)
Nature Cell Biology
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
90
-
-
79953202200
-
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
-
Arroyo, J.D., Chevillet, J.R., Kroh, E.M., Ruf, I.K., Pritchard, C.C., Gibson, D.F., et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proceedings of the National Academy of Sciences of the United States of America 108 (2011), 5003–5008.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, pp. 5003-5008
-
-
Arroyo, J.D.1
Chevillet, J.R.2
Kroh, E.M.3
Ruf, I.K.4
Pritchard, C.C.5
Gibson, D.F.6
-
91
-
-
79953301730
-
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
-
Vickers, K.C., Palmisano, B.T., Shoucri, B.M., Shamburek, R.D., Remaley, A.T., MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nature Cell Biology 13 (2011), 423–433.
-
(2011)
Nature Cell Biology
, vol.13
, pp. 423-433
-
-
Vickers, K.C.1
Palmisano, B.T.2
Shoucri, B.M.3
Shamburek, R.D.4
Remaley, A.T.5
-
92
-
-
85015317590
-
Adipose-derived circulating miRNAs regulate gene expression in other tissues
-
Thomou, T., Mori, M.A., Dreyfuss, J.M., Konishi, M., Sakaguchi, M., Wolfrum, C., et al. Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature 542 (2017), 450–455.
-
(2017)
Nature
, vol.542
, pp. 450-455
-
-
Thomou, T.1
Mori, M.A.2
Dreyfuss, J.M.3
Konishi, M.4
Sakaguchi, M.5
Wolfrum, C.6
-
93
-
-
84875033024
-
Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations
-
Williams, Z., Ben-Dov, I.Z., Elias, R., Mihailovic, A., Brown, M., Rosenwaks, Z., et al. Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations. Proceedings of the National Academy of Sciences of the United States of America 110 (2013), 4255–4260.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, pp. 4255-4260
-
-
Williams, Z.1
Ben-Dov, I.Z.2
Elias, R.3
Mihailovic, A.4
Brown, M.5
Rosenwaks, Z.6
-
94
-
-
80155210177
-
Circulating microRNA expression is reduced in chronic kidney disease
-
Neal, C.S., Michael, M.Z., Pimlott, L.K., Yong, T.Y., Li, J.Y.Z., Gleadle, J.M., Circulating microRNA expression is reduced in chronic kidney disease. Nephrology Dialysis Transplantation 26 (2011), 3794–3802.
-
(2011)
Nephrology Dialysis Transplantation
, vol.26
, pp. 3794-3802
-
-
Neal, C.S.1
Michael, M.Z.2
Pimlott, L.K.3
Yong, T.Y.4
Li, J.Y.Z.5
Gleadle, J.M.6
-
95
-
-
84882693149
-
Circulating microRNAs as novel biomarkers for diabetes mellitus
-
Guay, C., Regazzi, R., Circulating microRNAs as novel biomarkers for diabetes mellitus. Nature Reviews Endocrinology 9 (2013), 513–521.
-
(2013)
Nature Reviews Endocrinology
, vol.9
, pp. 513-521
-
-
Guay, C.1
Regazzi, R.2
-
96
-
-
84872746026
-
Circulating miR-375 as a biomarker of β-cell death and diabetes in mice
-
Erener, S., Mojibian, M., Fox, J.K., Denroche, H.C., Kieffer, T.J., Circulating miR-375 as a biomarker of β-cell death and diabetes in mice. Endocrinology 154 (2013), 603–608.
-
(2013)
Endocrinology
, vol.154
, pp. 603-608
-
-
Erener, S.1
Mojibian, M.2
Fox, J.K.3
Denroche, H.C.4
Kieffer, T.J.5
-
97
-
-
84934985382
-
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future
-
Chappell, J., Watters, K.E., Takahashi, M.K., Lucks, J.B., A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future. Current Opinion in Chemical Biology 28 (2015), 47–56.
-
(2015)
Current Opinion in Chemical Biology
, vol.28
, pp. 47-56
-
-
Chappell, J.1
Watters, K.E.2
Takahashi, M.K.3
Lucks, J.B.4
-
98
-
-
58749095112
-
Viral and cellular messenger RNA targets of viral microRNAs
-
Cullen, B.R., Viral and cellular messenger RNA targets of viral microRNAs. Nature 457 (2009), 421–425.
-
(2009)
Nature
, vol.457
, pp. 421-425
-
-
Cullen, B.R.1
-
99
-
-
58149232358
-
Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo
-
Boudreau, R.L., Martins, I., Davidson, B.L., Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo. Molecular Therapy 17 (2009), 169–175.
-
(2009)
Molecular Therapy
, vol.17
, pp. 169-175
-
-
Boudreau, R.L.1
Martins, I.2
Davidson, B.L.3
-
100
-
-
34249279050
-
MicroRNA-133 controls cardiac hypertrophy
-
Carè, A., Catalucci, D., Felicetti, F., Bonci, D., Addario, A., Gallo, P., et al. MicroRNA-133 controls cardiac hypertrophy. Nature Medicine 13 (2007), 613–618.
-
(2007)
Nature Medicine
, vol.13
, pp. 613-618
-
-
Carè, A.1
Catalucci, D.2
Felicetti, F.3
Bonci, D.4
Addario, A.5
Gallo, P.6
-
101
-
-
34548316982
-
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
-
Ebert, M.S., Neilson, J.R., Sharp, P.A., MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nature Methods 4 (2007), 721–726.
-
(2007)
Nature Methods
, vol.4
, pp. 721-726
-
-
Ebert, M.S.1
Neilson, J.R.2
Sharp, P.A.3
-
102
-
-
34547497309
-
Target mimicry provides a new mechanism for regulation of microRNA activity
-
Franco-Zorrilla, J.M., Valli, A., Todesco, M., Mateos, I., Puga, M.I., Rubio-Somoza, I., et al. Target mimicry provides a new mechanism for regulation of microRNA activity. Nature Genetics 39 (2007), 1033–1037.
-
(2007)
Nature Genetics
, vol.39
, pp. 1033-1037
-
-
Franco-Zorrilla, J.M.1
Valli, A.2
Todesco, M.3
Mateos, I.4
Puga, M.I.5
Rubio-Somoza, I.6
-
103
-
-
28444469246
-
Silencing of microRNAs in vivo with ‘antagomirs’
-
Krützfeldt, J., Rajewsky, N., Braich, R., Rajeev, K.G., Tuschl, T., Manoharan, M., et al. Silencing of microRNAs in vivo with ‘antagomirs’. Nature 438 (2005), 685–689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krützfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
-
104
-
-
34250679405
-
Specificity, duplex degradation and subcellular localization of antagomirs
-
Krützfeldt, J., Kuwajima, S., Braich, R., Rajeev, K.G., Pena, J., Tuschl, T., et al. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Research 35 (2007), 2885–2892.
-
(2007)
Nucleic Acids Research
, vol.35
, pp. 2885-2892
-
-
Krützfeldt, J.1
Kuwajima, S.2
Braich, R.3
Rajeev, K.G.4
Pena, J.5
Tuschl, T.6
-
105
-
-
35148815670
-
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
-
Wolfrum, C., Shi, S., Jayaprakash, K.N., Jayaraman, M., Wang, G., Pandey, R.K., et al. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nature Biotechnology 25 (2007), 1149–1157.
-
(2007)
Nature Biotechnology
, vol.25
, pp. 1149-1157
-
-
Wolfrum, C.1
Shi, S.2
Jayaprakash, K.N.3
Jayaraman, M.4
Wang, G.5
Pandey, R.K.6
-
106
-
-
77953801618
-
Target RNA-directed trimming and tailing of small silencing RNAs
-
Ameres, S.L., Horwich, M.D., Hung, J.H., Xu, J., Ghildiyal, M., Weng, Z., et al. Target RNA-directed trimming and tailing of small silencing RNAs. Science 328 (2010), 1534–1539.
-
(2010)
Science
, vol.328
, pp. 1534-1539
-
-
Ameres, S.L.1
Horwich, M.D.2
Hung, J.H.3
Xu, J.4
Ghildiyal, M.5
Weng, Z.6
-
107
-
-
84880770383
-
Diversifying microRNA sequence and function
-
Ameres, S.L., Phillip, D., Zamore, P., Diversifying microRNA sequence and function. Nature Reviews Molecular Cell Biology 14 (2013), 475–488.
-
(2013)
Nature Reviews Molecular Cell Biology
, vol.14
, pp. 475-488
-
-
Ameres, S.L.1
Phillip, D.2
Zamore, P.3
-
108
-
-
33646715590
-
Improved targeting of miRNA with antisense oligonucleotides
-
Davis, S., Lollo, B., Freier, S., Esau, C., Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Research 34 (2006), 2294–2304.
-
(2006)
Nucleic Acids Research
, vol.34
, pp. 2294-2304
-
-
Davis, S.1
Lollo, B.2
Freier, S.3
Esau, C.4
-
109
-
-
33646027887
-
LNA-modified oligonucleotides mediate specific inhibition of microRNA function
-
Ørom, U.A., Kauppinen, S., Lund, A.H., LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 372 (2006), 137–141.
-
(2006)
Gene
, vol.372
, pp. 137-141
-
-
Ørom, U.A.1
Kauppinen, S.2
Lund, A.H.3
-
110
-
-
77955469975
-
A direct comparison of anti-microRNA oligonucleotide potency
-
Lennox, K.A., Behlke, M.A., A direct comparison of anti-microRNA oligonucleotide potency. Journal of Pharmacy Research 27 (2010), 1788–1799.
-
(2010)
Journal of Pharmacy Research
, vol.27
, pp. 1788-1799
-
-
Lennox, K.A.1
Behlke, M.A.2
-
111
-
-
79958292714
-
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
-
Maekawa, M., Yamaguchi, K., Nakamura, T., Shibukawa, R., Kodanaka, I., Ichisaka, T., et al. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 474 (2011), 225–229.
-
(2011)
Nature
, vol.474
, pp. 225-229
-
-
Maekawa, M.1
Yamaguchi, K.2
Nakamura, T.3
Shibukawa, R.4
Kodanaka, I.5
Ichisaka, T.6
-
112
-
-
84897499406
-
MiRNA-375 promotes beta pancreatic differentiation in human induced pluripotent stem (hiPS) cells
-
Lahmy, R., Soleimani, M., Sanati, M.H., Behmanesh, M., Kouhkan, F., Mobarra, N., MiRNA-375 promotes beta pancreatic differentiation in human induced pluripotent stem (hiPS) cells. Molecular Biology Reports 41 (2014), 2055–2066.
-
(2014)
Molecular Biology Reports
, vol.41
, pp. 2055-2066
-
-
Lahmy, R.1
Soleimani, M.2
Sanati, M.H.3
Behmanesh, M.4
Kouhkan, F.5
Mobarra, N.6
-
113
-
-
85027936868
-
Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection
-
Shaer, A., Azarpira, N., Karimi, M.H., Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection. Applied Biochemistry and Biotechnology 174 (2014), 242–258.
-
(2014)
Applied Biochemistry and Biotechnology
, vol.174
, pp. 242-258
-
-
Shaer, A.1
Azarpira, N.2
Karimi, M.H.3
-
114
-
-
84946022760
-
Embryonic stem cell-derived pancreatic endoderm transplant with MCT1-suppressing miR-495 attenuates type II diabetes in mice
-
Liang, D., Zhang, Y., Han, J., Wang, W., Liu, Y., Li, J., et al. Embryonic stem cell-derived pancreatic endoderm transplant with MCT1-suppressing miR-495 attenuates type II diabetes in mice. Endocrine Journal 62 (2015), 907–920.
-
(2015)
Endocrine Journal
, vol.62
, pp. 907-920
-
-
Liang, D.1
Zhang, Y.2
Han, J.3
Wang, W.4
Liu, Y.5
Li, J.6
-
115
-
-
84947735943
-
miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus
-
Mi, Y., Guo, N., He, T., Ji, J., Li, Z., Huang, P., miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus. Journal of Molecular Endocrinology 55 (2015), 219–229.
-
(2015)
Journal of Molecular Endocrinology
, vol.55
, pp. 219-229
-
-
Mi, Y.1
Guo, N.2
He, T.3
Ji, J.4
Li, Z.5
Huang, P.6
-
116
-
-
84866115684
-
MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells
-
Zhao, X., Mohan, R., Özcan, S., Tang, X., MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells. Journal of Biological Chemistry 287 (2012), 31155–31164.
-
(2012)
Journal of Biological Chemistry
, vol.287
, pp. 31155-31164
-
-
Zhao, X.1
Mohan, R.2
Özcan, S.3
Tang, X.4
-
117
-
-
58249107416
-
Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription
-
Tang, X., Muniappan, L., Tang, G., Özcan, S., Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription. RNA 15 (2009), 287–293.
-
(2009)
RNA
, vol.15
, pp. 287-293
-
-
Tang, X.1
Muniappan, L.2
Tang, G.3
Özcan, S.4
-
118
-
-
84930086094
-
MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion
-
Sebastiani, G., Po, A., Miele, E., Ventriglia, G., Ceccarelli, E., Bugliani, M., et al. MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion. Acta Diabetologica 52 (2015), 523–530.
-
(2015)
Acta Diabetologica
, vol.52
, pp. 523-530
-
-
Sebastiani, G.1
Po, A.2
Miele, E.3
Ventriglia, G.4
Ceccarelli, E.5
Bugliani, M.6
-
119
-
-
84924801936
-
Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells
-
Salunkhe, V.A., Esguerra, J.L., Ofori, J.K., Mollet, I.G., Braun, M., Stoffel, M., et al. Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells. Acta Physiologica (Oxford) 213 (2015), 882–892.
-
(2015)
Acta Physiologica (Oxford)
, vol.213
, pp. 882-892
-
-
Salunkhe, V.A.1
Esguerra, J.L.2
Ofori, J.K.3
Mollet, I.G.4
Braun, M.5
Stoffel, M.6
-
120
-
-
77951158889
-
Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells
-
Roggli, E., Britan, A., Gattesco, S., Lin-Marg, N., Abderrahmani, A., Meda, P., et al. Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes 59 (2010), 978–986.
-
(2010)
Diabetes
, vol.59
, pp. 978-986
-
-
Roggli, E.1
Britan, A.2
Gattesco, S.3
Lin-Marg, N.4
Abderrahmani, A.5
Meda, P.6
-
121
-
-
84940727894
-
Induction of miR-132 and miR-212 expression by glucagon-like peptide 1 (GLP-1) in rodent and human pancreatic β-cells
-
Shang, J., Li, J., Keller, M.P., Hohmeier, H.E., Wang, Y., Feng, Y., et al. Induction of miR-132 and miR-212 expression by glucagon-like peptide 1 (GLP-1) in rodent and human pancreatic β-cells. Molecular Endocrinology 29 (2015), 1243–1253.
-
(2015)
Molecular Endocrinology
, vol.29
, pp. 1243-1253
-
-
Shang, J.1
Li, J.2
Keller, M.P.3
Hohmeier, H.E.4
Wang, Y.5
Feng, Y.6
-
122
-
-
84874432277
-
MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells
-
Wang, Y., Liu, J., Liu, C., Naji, A., Stoffers, D.A., MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells. Diabetes 62 (2013), 887–895.
-
(2013)
Diabetes
, vol.62
, pp. 887-895
-
-
Wang, Y.1
Liu, J.2
Liu, C.3
Naji, A.4
Stoffers, D.A.5
-
123
-
-
85016157333
-
Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
-
Ofori, J.K., Salunkhe, V.A., Bagge, A., Vishnu, N., Nagao, M., Mulder, H., Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell. Scientific Reports, 7, 2017, 44986.
-
(2017)
Scientific Reports
, vol.7
-
-
Ofori, J.K.1
Salunkhe, V.A.2
Bagge, A.3
Vishnu, N.4
Nagao, M.5
Mulder, H.6
-
124
-
-
79960322580
-
miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)
-
Pullen, T.J., da Silva Xavier, G., Kelsey, G., Rutter, G.A., miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1). Molecular and Cellular Biology 31 (2011), 3182–3194.
-
(2011)
Molecular and Cellular Biology
, vol.31
, pp. 3182-3194
-
-
Pullen, T.J.1
da Silva Xavier, G.2
Kelsey, G.3
Rutter, G.A.4
-
125
-
-
84888205573
-
Regulation of ABCA1 protein expression and function in hepatic and pancreatic islet cells by miR-145
-
Kang, M.H., Zhang, L.H., Wijesekara, N., de Haan, W., Butland, S., Bhattacharjee, A., et al. Regulation of ABCA1 protein expression and function in hepatic and pancreatic islet cells by miR-145. Arteriosclerosis Thrombosis and Vascular Biology 33 (2013), 2724–2732.
-
(2013)
Arteriosclerosis Thrombosis and Vascular Biology
, vol.33
, pp. 2724-2732
-
-
Kang, M.H.1
Zhang, L.H.2
Wijesekara, N.3
de Haan, W.4
Butland, S.5
Bhattacharjee, A.6
-
126
-
-
84863150557
-
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets
-
Wijesekara, N., Zhang, L.H., Kang, M.H., Abraham, T., Bhattacharjee, A., Warnock, G.L., et al. miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets. Diabetes 61 (2012), 653–658.
-
(2012)
Diabetes
, vol.61
, pp. 653-658
-
-
Wijesekara, N.1
Zhang, L.H.2
Kang, M.H.3
Abraham, T.4
Bhattacharjee, A.5
Warnock, G.L.6
|