MicroRNAs 106b and 222 Improve Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes via Pancreatic β-Cell Proliferation

EBioMedicine

Volumn 15, Issue , 2017, Pages 163-172

  Tsukita, Sohei ^a   Yamada, Tetsuya ^a   Takahashi, Kei ^a   Munakata, Yuichiro ^a   Hosaka, Shinichiro ^a   Takahashi, Hironobu ^a   Gao, Junhong ^a,b   Shirai, Yuta ^a   Kodama, Shinjiro ^a   Asai, Yoichiro ^a   Sugisawa, Takashi ^a   Chiba, Yumiko ^a   Kaneko, Keizo ^a   Uno, Kenji ^a   Sawada, Shojiro ^a   Imai, Junta ^a   Katagiri, Hideki ^a,c  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT   (Japan)

Author keywords

Cip Kip family; Diabetes; Exosomes; MicroRNAs; cell regeneration

Indexed keywords

ATELOCOLLAGEN; COMPLEMENTARY DNA; DNA NUCLEOTIDYLEXOTRANSFERASE; MICRORNA; MICRORNA 106B 5P; MICRORNA 222; MICRORNA 222 3P; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; CIB1 PROTEIN, MOUSE; CIP PROTEIN, MOUSE; MIRN106 MICRORNA, MOUSE; MIRN222 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; LASER CAPTURE MICRODISSECTION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RNA EXTRACTION; TUNEL ASSAY; ANIMAL; BLOOD; BONE MARROW CELL; DISEASE MODEL; EXOSOME; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PANCREAS ISLET; REGENERATION; RNA INTERFERENCE;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; EXOSOMES; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; MICRORNAS; REGENERATION; RNA INTERFERENCE;

EID: 85008222752     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2016.12.002     Document Type: Article

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