MiRNAs control insulin content in pancreatic β 2-cells via downregulation of transcriptional repressors

EMBO Journal

Volumn 30, Issue 5, 2011, Pages 835-845

  Melkman Zehavi, Tal ^a   Oren, Roni ^a   Kredo Russo, Sharon ^a   Shapira, Tirosh ^a   Mandelbaum, Amitai D ^a   Rivkin, Natalia ^a   Nir, Tomer ^b   Lennox, Kim A ^c   Behlke, Mark A ^c   Dor, Yuval ^b   Hornstein, Eran ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HEBREW UNIVERSITY   (Israel)

^c INTEGRATED DNA TECHNOLOGIES   (United States)

Author keywords

diabetes; Dicer1; insulin; miRNA; post transcriptional

Indexed keywords

GHRELIN; GLUCAGON; GREEN FLUORESCENT PROTEIN; INSULIN; MESSENGER RNA; MICRORNA; PANCREAS POLYPEPTIDE; SOMATOSTATIN; SYNAPTOPHYSIN; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN SYNTHESIS; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; DEAD-BOX RNA HELICASES; DOWN-REGULATION; ENDORIBONUCLEASES; GLUCOSE INTOLERANCE; HUMANS; IMMUNOENZYME TECHNIQUES; INSULIN; INSULIN-SECRETING CELLS; INTEGRASES; LUCIFERASES; MICE; MICE, KNOCKOUT; MICRORNAS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

ANIMALIA; MUS;

EID: 79952259862     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.361     Document Type: Article

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