Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

Diabetologia

Volumn 56, Issue 10, 2013, Pages 2203-2212

  Nesca, Valeria ^a   Guay, Claudiane ^a   Jacovetti, Cécile ^a   Menoud, Véronique ^a   Peyot, Marie Line ^b   Laybutt, D Ross ^c   Prentki, Marc ^b   Regazzi, Romano ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c ST VINCENT S HOSPITAL   (Australia)

Author keywords

Apoptosis; Beta cell; Diabetes; High fat diet; Insulin resistance; MicroRNA; Obesity; Pancreatic islet; Secretion

Indexed keywords

MICRORNA; MICRORNA 132; MICRORNA 146A; MICRORNA 184; MICRORNA 199A 3P; MICRORNA 203; MICRORNA 338 3P; MICRORNA 34A; MICRORNA 383; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN RESISTANCE; MALE; MOLECULAR PATHOLOGY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; RNA ANALYSIS;

ANIMALS; APOPTOSIS; CELL LINE; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; HUMANS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; OBESITY; RATS; RATS, WISTAR;

EID: 84890124194     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-013-2993-y     Document Type: Article

References (50)

1. Prentki M, Nolan CJ (2006) Islet beta cell failure in type 2 diabetes. J Clin Invest 116:1802-1812
2. Schofield CJ, Sutherland C (2012) Disordered insulin secretion in the development of insulin resistance and type 2 diabetes. Diabet Med 29:972-979
3. Sayed D, Abdellatif M (2011) MicroRNAs in development and disease. Physiol Rev 91:827-887
4. Guay C, Jacovetti C, Nesca V, Motterle A, Tugay K, Regazzi R (2012) Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction. Diabetes Obes Metab 14(Suppl 3):12-21
5. Zhao E, Keller MP, Rabaglia ME et al (2009) Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mamm Genome 20:476-485
6. Lovis P, Roggli E, Laybutt DR et al (2008) Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes 57:2728-2736
7. Esguerra JL, Bolmeson C, Cilio CM, Eliasson L (2011) Differential glucose-regulation of MicroRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat. PLoS One 6:e18613
8. Roggli E, Britan A, Gattesco S et al (2010) Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes 59:978-986
9. Jacovetti C, Abderrahmani A, Parnaud G et al (2012) MicroRNAs contribute to compensatory beta cell expansion during pregnancy and obesity. J Clin Invest 122:3541-3551
10. Chan JY, Luzuriaga J, Bensellam M, Biden TJ, Laybutt DR (2013) Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in beta-cell gene expression and progression to diabetes. Diabetes 62:1557-1568
11. Peyot ML, Pepin E, Lamontagne J et al (2010) Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes 59:2178-2187
12. Gotoh M, Maki T, Satomi S et al (1987) Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation 43:725-730
13. Lilla V, Webb G, Rickenbach K et al (2003) Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinology 144:1368-1379
14. Roggli E, Gattesco S, Caille D et al (2012) Changes in microRNA expression contribute to pancreatic beta-cell dysfunction in prediabetic NOD mice. Diabetes 61:1742-1751
15. Roche E, Buteau J, Aniento I, Reig JA, Soria B, Prentki M (1999) Palmitate and oleate induce the immediate-early response genes c-fos and nur-77 in the pancreatic beta-cell line INS-1. Diabetes 48:2007-2014
16. Coppola T, Frantz C, Perret-Menoud V, Gattesco S, Hirling H, Regazzi R (2002) Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis. Mol Biol Cell 13:1906-1915
17. Kobayashi K, Forte TM, Taniguchi S, Ishida BY, Oka K, Chan L (2000) The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding. Metabolism 49:22-31
18. Melkman-Zehavi T, Oren R, Kredo-Russo S et al (2011) miRNAs control insulin content in pancreatic beta-cells via downregulation of transcriptional repressors. EMBO J 30:835-845
19. Kornfeld JW, Baitzel C, Konner AC et al (2013) Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature 494:111-115
20. Lupi R, Del Prato S (2008) Beta-cell apoptosis in type 2 diabetes: quantitative and functional consequences. Diabetes Metab 34(Suppl 2):S56-S64
21. Fornari F, Milazzo M, Chieco P et al (2010) MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res 70:5184-5193
22. Xie J, Herbert TP (2012) The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic beta-cell mass: implications in the development of type-2 diabetes. Cell Mol Life Sci 69:1289-1304
23. Mellado-Gil J, Rosa TC, Demirci C et al (2011) Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes. Diabetes 60:525-536
24. Liu Y, Tanabe K, Baronnier D et al (2010) Conditional ablation of Gsk-3beta in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice. Diabetologia 53:2600-2610
25. Liu Z, Tanabe K, Bernal-Mizrachi E, Permutt MA (2008) Mice with beta cell overexpression of glycogen synthase kinase-3beta have reduced beta cell mass and proliferation. Diabetologia 51:623-631
26. Guo H, Ingolia NT, Weissman JS, Bartel DP (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466:835-840
27. Davis DB, Lavine JA, Suhonen JI et al (2010) FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol 24:1822-1834
28. Hang Y, Stein R (2011) MafA and MafB activity in pancreatic beta cells. Trends Endocrinol Metab 22:364-373
29. Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR (2004) PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. J Clin Invest 114:828-836
30. Bolmeson C, Esguerra JL, Salehi A, Speidel D, Eliasson L, Cilio CM (2011) Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects. Biochem Biophys Res Commun 404:16-22
31. Lovis P, Gattesco S, Regazzi R (2008) Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs. Biol Chem 389(3):305-312
32. Plaisance V, Abderrahmani A, Perret-Menoud V, Jacquemin P, Lemaigre F, Regazzi R (2006) MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. J Biol Chem 281:26932-26942
33. Baroukh N, Ravier MA, Loder MK et al (2007) MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem 282:19575-19588
34. Poy MN, Hausser J, Trajkovski M et al (2009) miR-375 maintains normal pancreatic alpha- and beta-cell mass. Proc Natl Acad Sci U S A 106:5813-5818
35. Nudelman AS, DiRocco DP, Lambert TJ et al (2010) Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo. Hippocampus 20:492-498
36. Remenyi J, Hunter CJ, Cole C et al (2010) Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins. Biochem J 428:281-291
37. Pathania M, Torres-Reveron J, Yan L et al (2012) miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons. PLoS One 7:e38174
38. Scott HL, Tamagnini F, Narduzzo KE et al (2012) MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex. Eur J Neurosci 36:2941-2948
39. Lin LF, Chiu SP, Wu MJ, Chen PY, Yen JH (2012) Luteolin induces microRNA-132 expression and modulates neurite outgrowth in PC12 cells. PLoS One 7:e43304
40. Numakawa T, Yamamoto N, Chiba S et al (2011) Growth factors stimulate expression of neuronal and glial miR-132. Neurosci Lett 505:242-247
41. Keller DM, Clark EA, Goodman RH (2012) Regulation of microRNA-375 by cAMP in pancreatic beta-cells. Mol Endocrinol 26:989-999
42. Hagman DK, Hays LB, Parazzoli SD, Poitout V (2005) Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans. J Biol Chem 280:32413-32418
43. Matsuoka TA, Kaneto H, Miyatsuka T et al (2010) Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes. Diabetes 59:1709-1720
44. Butler AE, Robertson RP, Hernandez R, Matveyenko AV, Gurlo T, Butler PC (2012) Beta cell nuclear musculoaponeurotic fibrosarcoma oncogene family A (MafA) is deficient in type 2 diabetes. Diabetologia 55:2985-2988
45. Ru P, Steele R, Hsueh EC, Ray RB (2011) Anti-miR-203 upregulates SOCS3 expression in breast cancer cells and enhances cisplatin chemosensitivity. Genes Cancer 2:720-727
46. Liu Y, Han Y, Zhang H et al (2012) Synthetic miRNA-mowers targeting miR-183-96-182 cluster or miR-210 inhibit growth and migration and induce apoptosis in bladder cancer cells. PLoS One 7:e52280
47. Li KK, Pang JC, Lau KM et al (2012) MiR-383 is downregulated in medulloblastoma and targets peroxiredoxin 3 (PRDX3). Brain Pathol 23(4):413-425
48. Kim S, Lee UJ, Kim MN et al (2008) MicroRNA miR-199a * regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2). J Biol Chem 283:18158-18166
49. Mori H, Inoki K, Opland D et al (2009) Critical roles for the TSC-mTOR pathway in beta-cell function. Am J Physiol Endocrinol Metab 297:E1013-E1022
50. Las G, Shirihai OS (2010) The role of autophagy in beta-cell lipotoxicity and type 2 diabetes. Diabetes Obes Metab 12(Suppl 2):15-19