-
1
-
-
56249094164
-
Type 1 diabetes: Chronic progressive autoimmune disease
-
Zhang L, Gianani R, Nakayama M et al. Type 1 diabetes: chronic progressive autoimmune disease. Novartis Found Symp 2008;292:85-94
-
(2008)
Novartis Found Symp
, vol.292
, pp. 85-94
-
-
Zhang, L.1
Gianani, R.2
Nakayama, M.3
-
2
-
-
67649364114
-
The role of inflammation in insulitis and beta-cell loss in type 1 diabetes
-
Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and beta-cell loss in type 1 diabetes. Nat Rev Endocrinol 2009;5:219-226
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 219-226
-
-
Eizirik, D.L.1
Colli, M.L.2
Ortis, F.3
-
3
-
-
0030030057
-
Cytokines and nitric oxide in islet inflammation and diabetes
-
McDaniel ML, Kwon G, Hill JR et al. Cytokines and nitric oxide in islet inflammation and diabetes. Proc Soc Exp Biol Med 1996;211:24-32
-
(1996)
Proc Soc Exp Biol Med
, vol.211
, pp. 24-32
-
-
McDaniel, M.L.1
Kwon, G.2
Hill, J.R.3
-
4
-
-
43549093332
-
Cytokines and beta-cell biology: From concept to clinical translation
-
Donath MY, Storling J, Berchtold LA et al. Cytokines and beta-cell biology: from concept to clinical translation. Endocr Rev 2008;29:334-350
-
(2008)
Endocr Rev
, vol.29
, pp. 334-350
-
-
Donath, M.Y.1
Storling, J.2
Berchtold, L.A.3
-
5
-
-
0347444723
-
Micrornas: Genomics, biogenesis, mechanism, and function
-
Bartel DP. Micrornas: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
77955644289
-
Mammalian micrornas predominantly act to decrease target mRNA levels
-
Guo H, Ingolia NT, Weissman JS et al. Mammalian micrornas predominantly act to decrease target mrna levels. Nature 2010;466: 835-840
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
-
7
-
-
35348821616
-
Micrornas in vertebrate physiology and human disease
-
Chang TC, Mendell JT. Micrornas in vertebrate physiology and human disease. Annu Rev Genomics Hum Genet 2007;8:215-239
-
(2007)
Annu Rev Genomics Hum Genet
, vol.8
, pp. 215-239
-
-
Chang, T.C.1
Mendell, J.T.2
-
8
-
-
9144270691
-
A pancreatic islet-specific Micro RNA regulates insulin secretion
-
Poy MN, Eliasson L, Krutzfeldt J et al. A pancreatic islet-specific Micro RNA regulates insulin secretion. Nature 2004;432:226-230
-
(2004)
Nature
, vol.432
, pp. 226-230
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
-
9
-
-
33748749597
-
Microrna-9 controls the expression of granuphilin/slp4 and the secretory response of insulin-producing cells
-
Plaisance V, Abderrahmani A, Perret-Menoud V et al. Microrna-9 controls the expression of granuphilin/slp4 and the secretory response of insulin-producing cells. J Biol Chem 2006;281:26932-26942
-
(2006)
J Biol Chem
, vol.281
, pp. 26932-26942
-
-
Plaisance, V.1
Abderrahmani, A.2
Perret-Menoud, V.3
-
10
-
-
34547126004
-
Microrna-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines
-
Baroukh N, Ravier MA, Loder MK et al. Microrna-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem 2007;282:19575-19588
-
(2007)
J Biol Chem
, vol.282
, pp. 19575-19588
-
-
Baroukh, N.1
Ma, R.2
Loder, M.K.3
-
11
-
-
40149083894
-
Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by micrornas
-
Lovis P, Gattesco S, Regazzi R. Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by micrornas. Biol Chem 2008;389:305-312
-
(2008)
Biol Chem
, vol.389
, pp. 305-312
-
-
Lovis, P.1
Gattesco, S.2
Regazzi, R.3
-
12
-
-
58149350343
-
Mir-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucoseinduced biological responses in pancreatic beta-cells
-
El Ouaamari A, Baroukh N, Martens GA et al. Mir-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucoseinduced biological responses in pancreatic beta-cells. Diabetes 2008;57:2708-2717
-
(2008)
Diabetes
, vol.57
, pp. 2708-2717
-
-
El Ouaamari, A.1
Baroukh, N.2
Martens, G.A.3
-
13
-
-
58149350340
-
Alterations in Micro RNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction
-
Lovis P, Roggli E, Laybutt DR et al. Alterations in Micro RNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes 2008;57:2728-2736
-
(2008)
Diabetes
, vol.57
, pp. 2728-2736
-
-
Lovis, P.1
Roggli, E.2
Laybutt, D.R.3
-
14
-
-
77951158889
-
Involvement of micrornas in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells
-
Roggli E, Britan A, Gattesco S et al. Involvement of micrornas in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes 2010;59:978-986
-
(2010)
Diabetes
, vol.59
, pp. 978-986
-
-
Roggli, E.1
Britan, A.2
Gattesco, S.3
-
15
-
-
84863228519
-
Changes in Micro RNA expression contribute to pancreatic beta-cell dysfunction in prediabetic Nod mice
-
Roggli E, Gattesco S, Caille D et al. Changes in Micro RNA expression contribute to pancreatic beta-cell dysfunction in prediabetic Nod mice. Diabetes 2012;61:1742-1751
-
(2012)
Diabetes
, vol.61
, pp. 1742-1751
-
-
Roggli, E.1
Gattesco, S.2
Caille, D.3
-
16
-
-
84859269961
-
Differential usage of Nf-Kappa b activating signals by Il-1beta and TNF-alpha in pancreatic beta cells
-
Ortis F, Miani M, Colli ML et al. Differential usage of Nf-Kappa b activating signals by Il-1beta and Tnf-alpha in pancreatic beta cells. FEBS Lett 2012;586:984-989
-
(2012)
FEBS Lett
, vol.586
, pp. 984-989
-
-
Ortis, F.1
Miani, M.2
Colli, M.L.3
-
17
-
-
0031897507
-
Human islets of langerhans express fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation
-
Loweth AC, Williams GT, James RF et al. Human islets of langerhans express fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation. Diabetes 1998;47:727-732
-
(1998)
Diabetes
, vol.47
, pp. 727-732
-
-
Loweth, A.C.1
Williams, G.T.2
James, R.F.3
-
18
-
-
0029665049
-
Cytokines activate the nuclear factor kappa B (Nf-Kappa B) and induce nitric oxide production in human pancreatic islets
-
Flodstrom M, Welsh N, Eizirik DL. Cytokines activate the nuclear factor kappa B (Nf-Kappa B) and induce nitric oxide production in human pancreatic islets. FEBS Lett 1996;385:4-6
-
(1996)
FEBS Lett
, vol.385
, pp. 4-6
-
-
Flodstrom, M.1
Welsh, N.2
Eizirik, D.L.3
-
19
-
-
84872507076
-
Microrna-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus
-
Yang J, Lu YW, Lu MM et al. Microrna-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus. Lupus 2013;22:115-120
-
(2013)
Lupus
, vol.22
, pp. 115-120
-
-
Yang, J.1
Lu, Y.W.2
Lu, M.M.3
-
20
-
-
78650643190
-
Microrna-101 targets Mapk phosphatase-1 to regulate the activation of Mapks in macrophages
-
Zhu QY, Liu Q, Chen JX et al. Microrna-101 targets Mapk phosphatase-1 to regulate the activation of Mapks in macrophages. J Immunol 2010;185:7435-7442
-
(2010)
J Immunol
, vol.185
, pp. 7435-7442
-
-
Zhu, Q.Y.1
Liu, Q.2
Chen, J.X.3
-
21
-
-
84893845668
-
Nf-kappab-mediated Mir-30b regulation in cardiomyocytes cell death by targeting Bcl-2
-
Wei C, Li L, Gupta S. Nf-kappab-mediated Mir-30b regulation in cardiomyocytes cell death by targeting Bcl-2. Mol Cell Biochem 2014;387:135-141
-
(2014)
Mol Cell Biochem
, vol.387
, pp. 135-141
-
-
Wei, C.1
Li, L.2
Gupta, S.3
-
22
-
-
53149104775
-
Glucose regulation of insulin gene expression in pancreatic beta-cells
-
Andrali SS, Sampley ML, Vanderford NL et al. Glucose regulation of insulin gene expression in pancreatic beta-cells. Biochem J 2008;415:1-10
-
(2008)
Biochem J
, vol.415
, pp. 1-10
-
-
Andrali, S.S.1
Sampley, M.L.2
Vanderford, N.L.3
-
23
-
-
0027944249
-
Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein Stf1/ Ipf1 acting through the Ct boxes
-
Petersen HV, Serup P, Leonard J et al. Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein Stf1/ Ipf1 acting through the Ct boxes. Proc Natl Acad Sci USA 1994;91: 10465-10469
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10465-10469
-
-
Petersen, H.V.1
Serup, P.2
Leonard, J.3
-
24
-
-
0028941181
-
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor
-
Naya FJ, Stellrecht CM, Tsai MJ. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev 1995;9:1009-1019
-
(1995)
Genes Dev
, vol.9
, pp. 1009-1019
-
-
Naya, F.J.1
Stellrecht, C.M.2
Tsai, M.J.3
-
25
-
-
43449091944
-
Pdx-1 and Mafa play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell funcation
-
Kaneto H, Miyatsuka T, Kawamori D et al. Pdx-1 and Mafa play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell funcation. Endocr J 2008;55:235-252
-
(2008)
Endocr J
, vol.55
, pp. 235-252
-
-
Kaneto, H.1
Miyatsuka, T.2
Kawamori, D.3
-
26
-
-
27844499690
-
Sox6 attenuates glucose-stimulated insulin secretion by repressing pdx1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice
-
Iguchi H, Ikeda Y, Okamura M et al. Sox6 attenuates glucose-stimulated insulin secretion by repressing pdx1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. J Biol Chem 2005;280:37669-37680
-
(2005)
J Biol Chem
, vol.280
, pp. 37669-37680
-
-
Iguchi, H.1
Ikeda, Y.2
Okamura, M.3
-
27
-
-
0032583520
-
Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats
-
Inada A, Yamada Y, Someya Y et al. Transcriptional repressors are increased in pancreatic islets of type 2 diabetic rats. Biochem Biophys Res Commun 1998;253:712-718
-
(1998)
Biochem Biophys Res Commun
, vol.253
, pp. 712-718
-
-
Inada, A.1
Yamada, Y.2
Someya, Y.3
-
28
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen J, Pedersen EE, Galante P et al. Control of endodermal endocrine development by Hes-1. Nat Genet 2000;24:36-44
-
(2000)
Nat Genet
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
-
30
-
-
0033556082
-
Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
-
Lang J. Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Eur J Biochem 1999;259:3-17
-
(1999)
Eur J Biochem
, vol.259
, pp. 3-17
-
-
Lang, J.1
-
31
-
-
37549048249
-
The Bcl-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. The Bcl-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008;9:47-59
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
32
-
-
70350028224
-
Signaling by Il-1beta+Ifn-gamma and Er stress converge on Dp5/Hrk activation: A novel mechanism for pancreatic beta-cell apoptosis
-
Gurzov EN, Ortis F, Cunha DA et al. Signaling by Il-1beta+Ifn-gamma and Er stress converge on Dp5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis. Cell Death Differ 2009;16:1539-1550
-
(2009)
Cell Death Differ
, vol.16
, pp. 1539-1550
-
-
Gurzov, E.N.1
Ortis, F.2
Cunha, D.A.3
-
33
-
-
79959618962
-
Bcl-2 proteins in diabetes: Mitochondrial pathways of beta-cell death and dysfunction
-
Gurzov EN, Eizirik DL. Bcl-2 proteins in diabetes: mitochondrial pathways of beta-cell death and dysfunction. Trends Cell Biol 2011;21:424-431
-
(2011)
Trends Cell Biol
, vol.21
, pp. 424-431
-
-
Gurzov, E.N.1
Eizirik, D.L.2
-
34
-
-
58149337392
-
Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling
-
Akerfeldt MC, Howes J, Chan JY et al. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. Diabetes 2008;57:3034-3044
-
(2008)
Diabetes
, vol.57
, pp. 3034-3044
-
-
Akerfeldt, M.C.1
Howes, J.2
Chan, J.Y.3
-
35
-
-
84884373262
-
Microrna-124 regulates Stat3 expression and Is down-regulated in colon tissues of pediatric patients with ulcerative colitis
-
Koukos G, Polytarchou C, Kaplan JL et al. Microrna-124 regulates Stat3 expression and Is down-regulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology 2013;145:842-852
-
(2013)
Gastroenterology
, vol.145
, pp. 842-852
-
-
Koukos, G.1
Polytarchou, C.2
Kaplan, J.L.3
|