PDGF signalling controls age-dependent proliferation in pancreatic β-cells

Nature

Volumn 478, Issue 7369, 2011, Pages 349-355

  Chen, Hainan ^a   Gu, Xueying ^a   Liu, Yinghua ^a   Wang, Jing ^a   Wirt, Stacey E ^a   Bottino, Rita ^b   Schorle, Hubert ^c   Sage, Julien ^a   Kim, Seung K ^a,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

AGE; BIOCHEMISTRY; BLOOD; CYTOLOGY; GENE EXPRESSION; HOMINID; JUVENILE; RODENT; SIGNALING;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; CHILD; CONTROLLED STUDY; DIABETES MELLITUS; GENE INACTIVATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULARLY TARGETED THERAPY; MOUSE; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES;

AGE FACTORS; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; E2F TRANSCRIPTION FACTORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKOUT TECHNIQUES; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION;

MUS;

EID: 80054991835     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10502     Document Type: Article

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