The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

Nature Medicine

Volumn 21, Issue 6, 2015, Pages 619-627

  Belgardt, Bengt Frederik ^a,b   Ahmed, Kashan ^a,b   Spranger, Martina ^a,b   Latreille, Mathieu ^a,b,g   Denzler, Remy ^a,b   Kondratiuk, Nadiia ^a,b   Von Meyenn, Ferdinand ^a,b,f   Villena, Felipe Nunez ^a,b   Herrmanns, Karolin ^a,b   Bosco, Domenico ^c   Kerr Conte, Julie ^d   Pattou, Francois ^d   Rülicke, Thomas ^e   Stoffel, Markus ^a,b  

^a ETH ZURICH   (Switzerland)

^b Competence Center for Systems Physiology and Metabolic Disease Swiss Federal Institute of Technology ^*  (Switzerland)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d UNIV LILLE   (France)

^e UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^f BABRAHAM INSTITUTE   (United Kingdom)

^g HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; MICRORNA; MICRORNA 141; MICRORNA 200; MICRORNA 200A; MICRORNA 200B; MICRORNA 200C; MICRORNA 429; PROTEIN; PROTEIN BAD; PROTEIN BAX; STREPTOZOCIN; TRP53 PROTEIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; DNAJC3 PROTEIN, MOUSE; HEAT SHOCK PROTEIN 40; MIRN200 MICRORNA, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DESTRUCTION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE CONTROL; GENE DOSAGE; GENE OVEREXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOBLOTTING; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; METABOLIC STRESS; MIN6 CELL LINE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE; SPONTANEOUS MUTATION; STRESS; TUNEL ASSAY; UPREGULATION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; APOPTOSIS; CELL SURVIVAL; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION REGULATION; HSP40 HEAT-SHOCK PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED NOD; MICRORNAS; SIGNAL TRANSDUCTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84930751975     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3862     Document Type: Article

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