Corrigendum: Adipose-derived circulating miRNAs regulate gene expression in other tissues (Nature (2017) 542 (450-455) DOI: 10.1038/nature21365);Adipose-derived circulating miRNAs regulate gene expression in other tissues

Nature

Volumn 542, Issue 7642, 2017, Pages 450-455

  Thomou, Thomas ^a   Mori, Marcelo A ^b   Dreyfuss, Jonathan M ^c,d   Konishi, Masahiro ^a   Sakaguchi, Masaji ^a   Wolfrum, Christian ^e   Rao, Tata Nageswara ^a,f   Winnay, Jonathon N ^a   Garcia Martin, Ruben ^a   Grinspoon, Steven K ^g   Gorden, Phillip ^h   Kahn, C Ronald ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Boston University   (United States)

^e ETH ZURICH   (Switzerland)

^f UNIVERSITY HOSPITAL BASEL   (Switzerland)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ADIPOCYTOKINE; ADIPONECTIN; DICER; FAT; FIBROBLAST GROWTH FACTOR 21; INTERLEUKIN 6; LEPTIN; MICRORNA; MICRORNA 16; MICRORNA 201; MICRORNA 221; MICRORNA 222; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; FIBROBLAST GROWTH FACTOR; MESSENGER RNA; MIRN99 MICRORNA, MOUSE; RIBONUCLEASE III;

ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE; LIPID; METABOLISM; RNA; RODENT; SERUM;

3' UNTRANSLATED REGION; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONGENITAL GENERALIZED LIPODYSTROPHY; CONTROLLED STUDY; EXOSOME; GENE CONTROL; GENE EXPRESSION; GENETIC RECOMBINATION; GLUCOSE TOLERANCE; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; HUMAN TISSUE; IMPAIRED GLUCOSE TOLERANCE; IN VIVO STUDY; INSULIN RESISTANCE; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RNA PROCESSING; WHITE ADIPOSE TISSUE; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; BLOOD; CYTOLOGY; DEFICIENCY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GLUCOSE TOLERANCE TEST; METABOLISM; PARACRINE SIGNALING; SECRETION (PROCESS); TRANSPLANTATION;

MUS;

3' UNTRANSLATED REGIONS; ADIPOKINES; ADIPOSE TISSUE; ADIPOSE TISSUE, BROWN; ADIPOSE TISSUE, WHITE; ANIMALS; EXOSOMES; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GENES, REPORTER; GLUCOSE TOLERANCE TEST; LIVER; MALE; MICE; MICRORNAS; MODELS, BIOLOGICAL; ORGAN SPECIFICITY; PARACRINE COMMUNICATION; RIBONUCLEASE III; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 85015317590     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature22319     Document Type: Erratum

References (50)

1. Krol, J., Loedige, I. & Filipowicz, W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610 (2010).
2. Sun, L. et al. Mir193b-365 is essential for brown fat differentiation. Nat. Cell Biol. 13, 958-965 (2011).
3. Trajkovski, M. et al. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474, 649-653 (2011).
4. Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
5. Ameres, S. L. & Zamore, P. D. Diversifying microRNA sequence and function. Nat. Rev. Mol. Cell Biol. 14, 475-488 (2013).
6. Arroyo, J. D. et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc. Natl Acad. Sci. USA 108, 5003-5008 (2011).
7. Thery, C., Amigorena, S., Raposo, G. & Clayton, A. Curr Protoc Cell Biol Chapter 3, Unit 3 22 (2006).
8. Gyorgy, B. et al. Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell. Mol. Life Sci. 68, 2667-2688 (2011).
9. Hata, A. & Lieberman, J. Dysregulation of microRNA biogenesis and gene silencing in cancer. Sci. Signal. 8, re3 (2015).
10. Dumortier, O., Hinault, C. & Van Obberghen, E. MicroRNAs and metabolism crosstalk in energy homeostasis. Cell Metab. 18, 312-324 (2013).
11. Arner, E. et al. Adipose tissue microRNAs as regulators of CCL2 production in human obesity. Diabetes 61, 1986-1993 (2012).
12. Capobianco, V. et al. miRNA and protein expression profiles of visceral adipose tissue reveal miR-141/YWHAG and miR-520e/RAB11A as two potential miRNA/protein target pairs associated with severe obesity. J. Proteome Res. 11, 3358-3369 (2012).
13. Caroli, A., Cardillo, M. T., Galea, R. & Biasucci, L. M. Potential therapeutic role of microRNAs in ischemic heart disease. J. Cardiol. 61, 315-320 (2013).
14. Guay, C., Roggli, E., Nesca, V., Jacovetti, C. & Regazzi, R. Diabetes mellitus, a microRNA-related disease? Transl. Res. 157, 253-264 (2011).
15. Mori, M. A. et al. Role of microRNA processing in adipose tissue in stress defense and longevity. Cell Metab. 16, 336-347 (2012).
16. Mori, M. A. et al. Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy. J. Clin. Invest. 124, 3339-3351 (2014).
17. Skog, J. et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 10, 1470-1476 (2008).
18. Taylor, D. D., Zacharias, W. & Gercel-Taylor, C. Exosome isolation for proteomic analyses and RNA profiling. Methods Mol. Biol. 728, 235-246 (2011).
19. Escola, J. M. et al. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J. Biol. Chem. 273, 20121-20127 (1998).
20. Fevrier, B. & Raposo, G. Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr. Opin. Cell Biol. 16, 415-421 (2004).
21. Ortega, F. J. et al. MiRNA expression profile of human subcutaneous adipose and during adipocyte differentiation. PLoS One 5, e9022 (2010).
22. Chou, W. W. et al. Decreased microRNA-221 is associated with high levels of TNF-a in human adipose tissue-derived mesenchymal stem cells from obese woman. Cell. Physiol. Biochem. 32, 127-137 (2013).
23. Oger, F. et al. Cell-specific dysregulation of microRNA expression in obese white adipose tissue. J. Clin. Endocrinol. Metab. 99, 2821-2833 (2014).
24. Keller, P. et al. Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity. BMC Endocr. Disord. 11, 7 (2011).
25. McGregor, R. A. & Choi, M. S. microRNAs in the regulation of adipogenesis and obesity. Curr. Mol. Med. 11, 304-316 (2011).
26. Potthoff, M. J., Kliewer, S. A. & Mangelsdorf, D. J. Endocrine fibroblast growth factors 15/19 and 21: from feast to famine. Genes Dev. 26, 312-324 (2012).
27. Badman, M. K. et al. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab. 5, 426-437 (2007).
28. Wong, N. & Wang, X. miRDB: an online resource for microRNA target prediction and functional annotations. Nucleic Acids Res. 43, D146-D152 (2015).
29. Yao, Y. et al. MicroRNA profiling of human gastric cancer. Mol. Med. Rep. 2, 963-970 (2009).
30. Uhrig-Schmidt, S. et al. Gene delivery to adipose tissue using transcriptionally targeted rAAV8 vectors. PLoS One 9, e116288 (2014).
31. Atai, N. A. et al. Heparin blocks transfer of extracellular vesicles between donor and recipient cells. J. Neurooncol. 115, 343-351 (2013).
32. Zech, D., Rana, S., Buchler, M. W. & Zoller, M. Tumor-exosomes and leukocyte activation: an ambivalent crosstalk. Cell Commun. Signal. 10, 37 (2012).
33. Valadi, H. et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9, 654-659 (2007).
34. Bluher, M. Adipokines -removing road blocks to obesity and diabetes therapy. Mol. Metab. 3, 230-240 (2014).
35. Thery, C., Ostrowski, M. & Segura, E. Membrane vesicles as conveyors of immune responses. Nat. Rev. Immunol. 9, 581-593 (2009).
36. Bang, C. et al. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. J. Clin. Invest. 124, 2136-2146 (2014).
37. Hergenreider, E. et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat. Cell Biol. 14, 249-256 (2012).
38. Mittelbrunn, M. et al. Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat. Commun. 2, 282 (2011).
39. Ismail, N. et al. Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood 121, 984-995 (2013).
40. Zernecke, A. et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci. Signal. 2, ra81 (2009).
41. van der Vos, K. E. et al. Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain. Neuro-oncol. 18, 58-69 (2016).
42. Yuan, A. et al. Transfer of microRNAs by embryonic stem cell microvesicles. PLoS One 4, e4722 (2009).
43. Gallo, A., Tandon, M., Alevizos, I. & Illei, G. G. The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS One 7, e30679 (2012).
44. Turchinovich, A., Weiz, L., Langheinz, A. & Burwinkel, B. Characterization of extracellular circulating microRNA. Nucleic Acids Res. 39, 7223-7233 (2011)
45. Tian, Y. et al. A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy. Biomaterials 35, 2383-2390 (2014).
46. Mathivanan, S., Fahner, C. J., Reid, G. E. & Simpson, R. J. ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic Acids Res. 40, D1241-D1244 (2012).
47. Mestdagh, P. et al. A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol. 10, R64 (2009).
48. Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3, Article3 (2004).
49. Eisen, M. B., Spellman, P. T., Brown, P. O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl Acad. Sci. USA 95, 14863-14868 (1998).
50. Tran, T. T., Yamamoto, Y., Gesta, S. & Kahn, C. R. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab. 7, 410-420 (2008).