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Volumn 131, Issue 11, 2017, Pages 1069-1092

Kidney, heart and brain: Three organs targeted by ageing and glycation

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AGER PROTEIN, HUMAN;

EID: 85020235257     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20160823     Document Type: Review
Times cited : (67)

References (250)
  • 1
    • 0000916315 scopus 로고
    • Action des acides aminés sur les sucres: formation des mélanöidines par voie méthodique [in French]
    • Maillard, L. (1912) Action des acides aminés sur les sucres: formation des mélanöidines par voie méthodique [in French]. C. R. Acad. Sci. 154, 66
    • (1912) C. R. Acad. Sci. , vol.154 , pp. 66
    • Maillard, L.1
  • 2
    • 77953621114 scopus 로고    scopus 로고
    • The Maillard reaction in the human body The main discoveries and factors that affect glycation.
    • Tessier, F.J. (2010) The Maillard reaction in the human body. The main discoveries and factors that affect glycation. Pathol. Biol. (Paris) 58, 214-2149
    • (2010) Pathol. Biol. (Paris) , vol.58 , pp. 214-2149
    • Tessier, F.J.1
  • 3
    • 84956677187 scopus 로고    scopus 로고
    • Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation
    • Delgado-Andrade, C. (2016) Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation. Food Funct. 7, 46-57
    • (2016) Food Funct. , vol.7 , pp. 46-57
    • Delgado-Andrade, C.1
  • 4
    • 0005485107 scopus 로고
    • New hemoglobin in normal adult blood
    • Kunkel, H.G. and Wallenius, G. (1955) New hemoglobin in normal adult blood. Science 122, 288
    • (1955) Science , vol.122 , pp. 288
    • Kunkel, H.G.1    Wallenius, G.2
  • 5
    • 0014346452 scopus 로고
    • An abnormal hemoglobin in red cells of diabetics
    • Rahbar, S. (1968) An abnormal hemoglobin in red cells of diabetics. Clin. Chim. Acta 22, 296-298
    • (1968) Clin. Chim. Acta , vol.22 , pp. 296-298
    • Rahbar, S.1
  • 6
    • 0000597981 scopus 로고
    • Aging of proteins and nucleic acids: what is the role of glucose
    • Cerami, A. (1986) Aging of proteins and nucleic acids: what is the role of glucose. Trends Biochem. Sci. 11, 311-314
    • (1986) Trends Biochem. Sci. , vol.11 , pp. 311-314
    • Cerami, A.1
  • 9
    • 84899789618 scopus 로고    scopus 로고
    • Glycation: the angiogenic paradox in aging and age-related disorders and diseases
    • Roca, F., Grossin, N., Chassagne, P., Puisieux, F. and Boulanger, E. (2014) Glycation: the angiogenic paradox in aging and age-related disorders and diseases. Ageing Res. Rev. 15, 146-160
    • (2014) Ageing Res. Rev. , vol.15 , pp. 146-160
    • Roca, F.1    Grossin, N.2    Chassagne, P.3    Puisieux, F.4    Boulanger, E.5
  • 10
    • 84913606113 scopus 로고    scopus 로고
    • Effect of advanced glycation end product intake on inflammation and aging: a systematic review
    • Van Puyvelde, K., Mets, T., Njemini, R., Beyer, I. and Bautmans, I. (2014) Effect of advanced glycation end product intake on inflammation and aging: a systematic review. Nutr. Rev. 72, 638-650
    • (2014) Nutr. Rev. , vol.72 , pp. 638-650
    • Van Puyvelde, K.1    Mets, T.2    Njemini, R.3    Beyer, I.4    Bautmans, I.5
  • 12
  • 13
    • 84862802237 scopus 로고    scopus 로고
    • Advanced glycation end-product Ne-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes
    • Wang, Z., Jiang, Y., Liu, N., Ren, L., Zhu, Y., An, Y. et al. (2012) Advanced glycation end-product Ne-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes. Atherosclerosis 221, 387-396
    • (2012) Atherosclerosis , vol.221 , pp. 387-396
    • Wang, Z.1    Jiang, Y.2    Liu, N.3    Ren, L.4    Zhu, Y.5    An, Y.6
  • 15
    • 84881240163 scopus 로고    scopus 로고
    • Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.
    • Vistoli, G., De Maddis, D., Cipak, A., Zarkovic, N., Carini, M. and Aldini, G. (2013) Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation. Free Radic. Res. 47 (sup1), 3-27
    • (2013) Free Radic. Res. , vol.47 , pp. 3-27
    • Vistoli, G.1    De Maddis, D.2    Cipak, A.3    Zarkovic, N.4    Carini, M.5    Aldini, G.6
  • 16
    • 0345711536 scopus 로고    scopus 로고
    • Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration
    • He, C., Sabol, J., Mitsuhashi, T. and Vlassara, H. (1999) Dietary glycotoxins: inhibition of reactive products by aminoguanidine facilitates renal clearance and reduces tissue sequestration. Diabetes 48, 1308-1315
    • (1999) Diabetes , vol.48 , pp. 1308-1315
    • He, C.1    Sabol, J.2    Mitsuhashi, T.3    Vlassara, H.4
  • 17
    • 0242468729 scopus 로고    scopus 로고
    • Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry.
    • Thornalley, P.J., Battah, S., Ahmed, N., Karachalias, N., Agalou, S., Babaei-Jadidi, R. et al. (2003) Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry. Biochem. J. 375 (Pt 3), 581-592
    • (2003) Biochem. J. , vol.375 , pp. 581-592
    • Thornalley, P.J.1    Battah, S.2    Ahmed, N.3    Karachalias, N.4    Agalou, S.5    Babaei-Jadidi, R.6
  • 18
    • 84920000582 scopus 로고    scopus 로고
    • Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes
    • Rabbani, N. and Thornalley, P.J. (2015) Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes. Diabetes 64, 9-11
    • (2015) Diabetes , vol.64 , pp. 9-11
    • Rabbani, N.1    Thornalley, P.J.2
  • 19
    • 0019796775 scopus 로고
    • Reaction of monosaccharides with proteins: possible evolutionary significance
    • Bunn, H.F. and Higgins, P.J. (1981) Reaction of monosaccharides with proteins: possible evolutionary significance. Science 213, 222-224
    • (1981) Science , vol.213 , pp. 222-224
    • Bunn, H.F.1    Higgins, P.J.2
  • 20
    • 23744447530 scopus 로고    scopus 로고
    • Dicarbonyl intermediates in the maillard reaction
    • Thornalley, P.J. (2005) Dicarbonyl intermediates in the maillard reaction. Ann. N.Y. Acad. Sci. 1043, 111-117
    • (2005) Ann. N.Y. Acad. Sci. , vol.1043 , pp. 111-117
    • Thornalley, P.J.1
  • 21
    • 84974688585 scopus 로고    scopus 로고
    • Pathways of the Maillard reaction under physiological conditions
    • Henning, C. and Glomb, M.A. (2016) Pathways of the Maillard reaction under physiological conditions. Glycoconj. J. 33, 499-512
    • (2016) Glycoconj. J. , vol.33 , pp. 499-512
    • Henning, C.1    Glomb, M.A.2
  • 22
    • 84978132217 scopus 로고    scopus 로고
    • Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
    • Rabbani, N., Xue, M. and Thornalley, P.J. (2016) Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics. Glycoconj. J. 33, 513-525
    • (2016) Glycoconj. J. , vol.33 , pp. 513-525
    • Rabbani, N.1    Xue, M.2    Thornalley, P.J.3
  • 25
    • 79954665442 scopus 로고    scopus 로고
    • Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions
    • Deppe, V.M., Bongaerts, J., O'Connell, T., Maurer, K.-H. and Meinhardt, F. (2011) Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions. Appl. Microbiol. Biotechnol. 90, 399-406
    • (2011) Appl. Microbiol. Biotechnol. , vol.90 , pp. 399-406
    • Deppe, V.M.1    Bongaerts, J.2    O'Connell, T.3    Maurer, K.-H.4    Meinhardt, F.5
  • 26
    • 0035668462 scopus 로고    scopus 로고
    • The AGE-receptor in the pathogenesis of diabetic complications
    • Vlassara, H. (2001) The AGE-receptor in the pathogenesis of diabetic complications. Diabetes Metab. Res. Rev. 17, 436-443
    • (2001) Diabetes Metab. Res. Rev. , vol.17 , pp. 436-443
    • Vlassara, H.1
  • 28
    • 0346100518 scopus 로고    scopus 로고
    • Scavenger receptors for oxidized and glycated proteins
    • Horiuchi, S., Sakamoto, Y. and Sakai, M. (2003) Scavenger receptors for oxidized and glycated proteins. Amino Acids 25, 283-292
    • (2003) Amino Acids , vol.25 , pp. 283-292
    • Horiuchi, S.1    Sakamoto, Y.2    Sakai, M.3
  • 30
    • 0033597866 scopus 로고    scopus 로고
    • Structure and mechanism of formation of human lens fluorophore LM-1 Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis.
    • Tessier, F., Obrenovich, M. and Monnier, V.M. (1999) Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis. J. Biol. Chem. 274, 20796-20804
    • (1999) J. Biol. Chem. , vol.274 , pp. 20796-20804
    • Tessier, F.1    Obrenovich, M.2    Monnier, V.M.3
  • 31
    • 84928528232 scopus 로고    scopus 로고
    • Comprehensive analysis of maillard protein modifications in human lenses: effect of age and cataract
    • Smuda, M., Henning, C., Raghavan, C.T., Johar, K., Vasavada, A.R., Nagaraj, R.H. et al. (2015) Comprehensive analysis of maillard protein modifications in human lenses: effect of age and cataract. Biochemistry 54, 2500-2507
    • (2015) Biochemistry , vol.54 , pp. 2500-2507
    • Smuda, M.1    Henning, C.2    Raghavan, C.T.3    Johar, K.4    Vasavada, A.R.5    Nagaraj, R.H.6
  • 32
    • 0027160460 scopus 로고
    • Accumulation of Maillard reaction products in skin collagen in diabetes and aging
    • Dyer, D.G., Dunn, J.A., Thorpe, S.R., Bailie, K.E., Lyons, T.J., McCance, D.R. et al. (1993) Accumulation of Maillard reaction products in skin collagen in diabetes and aging. J. Clin. Invest. 91, 2463-2469
    • (1993) J. Clin. Invest. , vol.91 , pp. 2463-2469
    • Dyer, D.G.1    Dunn, J.A.2    Thorpe, S.R.3    Bailie, K.E.4    Lyons, T.J.5    McCance, D.R.6
  • 33
    • 0034826534 scopus 로고    scopus 로고
    • Isolation and characterization of glyoxal-arginine modifications
    • Glomb, M.A. and Lang, G. (2001) Isolation and characterization of glyoxal-arginine modifications. J. Agric. Food Chem. 49, 1493-1501
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 1493-1501
    • Glomb, M.A.1    Lang, G.2
  • 34
    • 0037093336 scopus 로고    scopus 로고
    • Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysineand Nepsilon-(1-carboxyethyl)lysine-modified albumin.
    • Ahmed, N., Argirov, O.K., Minhas, H.S., Cordeiro, C.A.A. and Thornalley, P.J. (2002) Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysineand Nepsilon-(1-carboxyethyl)lysine-modified albumin. Biochem. J. 364 (Pt 1), 1-14
    • (2002) Biochem. J. , vol.364 , pp. 1-14
    • Ahmed, N.1    Argirov, O.K.2    Minhas, H.S.3    Cordeiro, C.A.A.4    Thornalley, P.J.5
  • 35
    • 78651113258 scopus 로고    scopus 로고
    • Formation of arginine modifications in a model system of Na-tert-butoxycarbonyl (Boc)-arginine with methylglyoxal
    • Klöpfer, A., Spanneberg, R. and Glomb, M.A. (2011) Formation of arginine modifications in a model system of Na-tert-butoxycarbonyl (Boc)-arginine with methylglyoxal. J. Agric. Food Chem. 59, 394-401
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 394-401
    • Klöpfer, A.1    Spanneberg, R.2    Glomb, M.A.3
  • 36
    • 0037067723 scopus 로고    scopus 로고
    • Identification and quantification of major Maillard cross-links in human serum albumin and lens protein vidence for glucosepane as the dominant compound.
    • Biemel, K.M. (2002) Identification and quantification of major Maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound. J. Biol. Chem. 277, 24907-24915
    • (2002) EJ. Biol. Chem. , vol.277 , pp. 24907-24915
    • Biemel, K.M.1
  • 37
    • 0034671714 scopus 로고    scopus 로고
    • Effect of collagen turnover on the accumulation of advanced glycation end products
    • Verzijl, N., DeGroot, J., Thorpe, S.R., Bank, R.A., Shaw, J.N., Lyons, T.J. et al. (2000) Effect of collagen turnover on the accumulation of advanced glycation end products. J. Biol. Chem. 275, 39027-39031
    • (2000) J. Biol. Chem. , vol.275 , pp. 39027-39031
    • Verzijl, N.1    DeGroot, J.2    Thorpe, S.R.3    Bank, R.A.4    Shaw, J.N.5    Lyons, T.J.6
  • 38
    • 0034659178 scopus 로고    scopus 로고
    • Glycoxidation and lipoxidation in atherogenesis
    • Baynes, J.W. and Thorpe, S.R. (2000) Glycoxidation and lipoxidation in atherogenesis. Free Radic. Biol. Med. 28, 1708-1716
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1708-1716
    • Baynes, J.W.1    Thorpe, S.R.2
  • 40
    • 84855830535 scopus 로고    scopus 로고
    • Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)
    • Uchiki, T., Weikel, K.A., Jiao, W., Shang, F., Caceres, A., Pawlak, D. et al. (2012) Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics). Aging Cell 11, 1-13
    • (2012) Aging Cell , vol.11 , pp. 1-13
    • Uchiki, T.1    Weikel, K.A.2    Jiao, W.3    Shang, F.4    Caceres, A.5    Pawlak, D.6
  • 43
    • 0030031177 scopus 로고    scopus 로고
    • Renal fate of circulating advanced glycated end products (AGE): evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells
    • Gugliucci, A. and Bendayan, M. (1996) Renal fate of circulating advanced glycated end products (AGE): evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells. Diabetologia 39, 149-160
    • (1996) Diabetologia , vol.39 , pp. 149-160
    • Gugliucci, A.1    Bendayan, M.2
  • 44
    • 0035995375 scopus 로고    scopus 로고
    • Renal proximal tubular metabolism of protein-linked pentosidine, an advanced glycation end product
    • Asano, M., Fujita, Y., Ueda, Y., Suzuki, D., Miyata, T., Sakai, H. et al. (2002) Renal proximal tubular metabolism of protein-linked pentosidine, an advanced glycation end product. Nephron 91, 688-694
    • (2002) Nephron , vol.91 , pp. 688-694
    • Asano, M.1    Fujita, Y.2    Ueda, Y.3    Suzuki, D.4    Miyata, T.5    Sakai, H.6
  • 46
    • 0030391546 scopus 로고    scopus 로고
    • Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine
    • Miyata, T., Ueda, Y., Shinzato, T., Iida, Y., Tanaka, S., Kurokawa, K. et al. (1996) Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine. J. Am. Soc. Nephrol. 7, 1198-1206
    • (1996) J. Am. Soc. Nephrol. , vol.7 , pp. 1198-1206
    • Miyata, T.1    Ueda, Y.2    Shinzato, T.3    Iida, Y.4    Tanaka, S.5    Kurokawa, K.6
  • 47
    • 79951992162 scopus 로고    scopus 로고
    • Associations of serum levels of advanced glycation end products with nutrition markers and anemia in patients with chronic kidney disease
    • Kratochvilová, M., Zakiyanov, O., Kalousová, M., Kŕiha, V., Zima, T. and Tesar V. (2011) Associations of serum levels of advanced glycation end products with nutrition markers and anemia in patients with chronic kidney disease. Ren. Fail. 33, 131-137
    • (2011) Ren. Fail. , vol.33 , pp. 131-137
    • Kratochvilová, M.1    Zakiyanov, O.2    Kalousová, M.3    Kŕiha, V.4    Zima, T.5    Tesar, V.6
  • 48
    • 22444445653 scopus 로고    scopus 로고
    • Profound mishandling of protein glycation degradation products in uremia and dialysis
    • Agalou, S., Ahmed, N., Babaei-Jadidi, R., Dawnay, A. and Thornalley, P.J. (2005) Profound mishandling of protein glycation degradation products in uremia and dialysis. J. Am. Soc. Nephrol. 16, 1471-185
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 1471-1485
    • Agalou, S.1    Ahmed, N.2    Babaei-Jadidi, R.3    Dawnay, A.4    Thornalley, P.J.5
  • 49
    • 4444227471 scopus 로고    scopus 로고
    • Normalization of oxidative stress parameters after kidney transplant is secondary to full recovery of renal function
    • Antolini, F., Valente, F., Ricciardi, D. and Fagugli, R.M. (2004) Normalization of oxidative stress parameters after kidney transplant is secondary to full recovery of renal function. Clin. Nephrol. 62, 131-137
    • (2004) Clin. Nephrol. , vol.62 , pp. 131-137
    • Antolini, F.1    Valente, F.2    Ricciardi, D.3    Fagugli, R.M.4
  • 50
    • 0019742621 scopus 로고
    • Metabolic transit of early and advanced Maillard products
    • Finot, P.A. and Magnenat, E. (1981) Metabolic transit of early and advanced Maillard products. Prog. Food Nutr. Sci. 5, 193-207
    • (1981) Prog. Food Nutr. Sci. , vol.5 , pp. 193-207
    • Finot, P.A.1    Magnenat, E.2
  • 51
    • 4444333899 scopus 로고    scopus 로고
    • Glycation, carbonyl stress, EAGLEs, and the vascular complications of diabetes
    • Lyons, T.J. (2002) Glycation, carbonyl stress, EAGLEs, and the vascular complications of diabetes. Semin. Vasc. Med. 2, 175-189
    • (2002) Semin. Vasc. Med. , vol.2 , pp. 175-189
    • Lyons, T.J.1
  • 53
    • 0030763201 scopus 로고    scopus 로고
    • Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging
    • Schleicher, E.D., Wagner, E. and Nerlich, A.G. (1997) Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. J. Clin. Invest. 99, 457-468
    • (1997) J. Clin. Invest. , vol.99 , pp. 457-468
    • Schleicher, E.D.1    Wagner, E.2    Nerlich, A.G.3
  • 54
    • 0031453830 scopus 로고    scopus 로고
    • Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
    • Horie, K., Miyata, T., Maeda, K., Miyata, S., Sugiyama, S., Sakai, H. et al. (1997) Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J. Clin. Invest. 100, 2995-3004
    • (1997) J. Clin. Invest. , vol.100 , pp. 2995-3004
    • Horie, K.1    Miyata, T.2    Maeda, K.3    Miyata, S.4    Sugiyama, S.5    Sakai, H.6
  • 55
    • 84862654327 scopus 로고    scopus 로고
    • Health effects of dietary Maillard reaction products: the results of ICARE and other studies
    • Tessier, F.J. and Birlouez-Aragon, I. (2012) Health effects of dietary Maillard reaction products: the results of ICARE and other studies. Amino Acids 42, 1119-1131
    • (2012) Amino Acids , vol.42 , pp. 1119-1131
    • Tessier, F.J.1    Birlouez-Aragon, I.2
  • 56
    • 84985990833 scopus 로고    scopus 로고
    • Quantitative assessment of organ distribution of dietary protein-bound (13) C-labeled N(?) -carboxymethyllysine after a chronic oral exposure in mice
    • Tessier, F.J., Niquet-Léridon, C., Jacolot, P., Jouquand, C., Genin, M., Schmidt, A.-M. et al. (2016) Quantitative assessment of organ distribution of dietary protein-bound (13) C-labeled N(?) -carboxymethyllysine after a chronic oral exposure in mice. Mol. Nutr. Food Res. 60, 2446-2456
    • (2016) Mol. Nutr. Food Res. , vol.60 , pp. 2446-2456
    • Tessier, F.J.1    Niquet-Léridon, C.2    Jacolot, P.3    Jouquand, C.4    Genin, M.5    Schmidt, A.-M.6
  • 57
    • 77955867860 scopus 로고    scopus 로고
    • Does accumulation of advanced glycation end products contribute to the aging phenotype
    • Semba, R.D., Nicklett, E.J. and Ferrucci, L. (2010) Does accumulation of advanced glycation end products contribute to the aging phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 65, 963-975
    • (2010) J. Gerontol. A Biol. Sci. Med. Sci. , vol.65 , pp. 963-975
    • Semba, R.D.1    Nicklett, E.J.2    Ferrucci, L.3
  • 58
    • 0030992848 scopus 로고    scopus 로고
    • Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy
    • Koschinsky, T., He, C.J., Mitsuhashi, T., Bucala, R., Liu, C., Buenting, C. et al. (1997) Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy. Proc. Natl. Acad. Sci. U.S.A. 94, 6474-6479
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 6474-6479
    • Koschinsky, T.1    He, C.J.2    Mitsuhashi, T.3    Bucala, R.4    Liu, C.5    Buenting, C.6
  • 59
    • 29144467932 scopus 로고    scopus 로고
    • Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods
    • Henle, T. (2005) Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods. Amino Acids 29, 313-322
    • (2005) Amino Acids , vol.29 , pp. 313-322
    • Henle, T.1
  • 60
    • 84962207552 scopus 로고    scopus 로고
    • Emerging targets for therapeutic development in diabetes and its complications: the RAGE signaling pathway
    • Litwinoff, E., Hurtado Del Pozo, C., Ramasamy, R. and Schmidt, A.M. (2015) Emerging targets for therapeutic development in diabetes and its complications: the RAGE signaling pathway. Clin. Pharmacol. Ther. 98, 135-144
    • (2015) Clin. Pharmacol. Ther. , vol.98 , pp. 135-144
    • Litwinoff, E.1    Hurtado Del Pozo, C.2    Ramasamy, R.3    Schmidt, A.M.4
  • 61
    • 84924060735 scopus 로고    scopus 로고
    • Advanced glycation end products induce endothelial-to-mesenchymal transition via downregulating Sirt 1 and upregulating TGF-ß in human endothelial cells
    • He, W., Zhang, J., Gan, T., Xu, G. and Tang, B. (2015) Advanced glycation end products induce endothelial-to-mesenchymal transition via downregulating Sirt 1 and upregulating TGF-ß in human endothelial cells. BioMed. Res. Int. 2015, 684242
    • (2015) BioMed. Res. Int. , vol.2015 , pp. 684242
    • He, W.1    Zhang, J.2    Gan, T.3    Xu, G.4    Tang, B.5
  • 62
    • 84922694268 scopus 로고    scopus 로고
    • SiRNA-HMGA2 weakened AGEs-induced epithelial-to-mesenchymal transition in tubular epithelial cells
    • Bai, Y.-H., Wang, J.-P., Yang, M., Zeng, Y. and Jiang, H.-Y. (2015) SiRNA-HMGA2 weakened AGEs-induced epithelial-to-mesenchymal transition in tubular epithelial cells. Biochem. Biophys. Res. Commun. 457, 730-735
    • (2015) Biochem. Biophys. Res. Commun. , vol.457 , pp. 730-735
    • Bai, Y.-H.1    Wang, J.-P.2    Yang, M.3    Zeng, Y.4    Jiang, H.-Y.5
  • 63
    • 0022615251 scopus 로고
    • Relation between complications of type I diabetes mellitus and collagen-linked fluorescence
    • Monnier, V.M., Vishwanath, V., Frank, K.E., Elmets, C.A., Dauchot, P. and Kohn, R.R. (1986) Relation between complications of type I diabetes mellitus and collagen-linked fluorescence. N. Engl. J. Med. 314, 403-408
    • (1986) N. Engl. J. Med. , vol.314 , pp. 403-408
    • Monnier, V.M.1    Vishwanath, V.2    Frank, K.E.3    Elmets, C.A.4    Dauchot, P.5    Kohn, R.R.6
  • 64
    • 84903288986 scopus 로고    scopus 로고
    • An advanced glycation end product (AGE)-rich diet promotes Nε-carboxymethyl-lysine accumulation in the cardiac tissue and tendons of rats
    • Roncero-Ramos, I., Niquet-Léridon, C., Strauch, C., Monnier, V.M., Tessier, F.J., Navarro, M.P. et al. (2014) An advanced glycation end product (AGE)-rich diet promotes Nε-carboxymethyl-lysine accumulation in the cardiac tissue and tendons of rats. J. Agric. Food. Chem. 62, 6001-6006
    • (2014) J. Agric. Food. Chem. , vol.62 , pp. 6001-6006
    • Roncero-Ramos, I.1    Niquet-Léridon, C.2    Strauch, C.3    Monnier, V.M.4    Tessier, F.J.5    Navarro, M.P.6
  • 65
    • 34948834721 scopus 로고    scopus 로고
    • Dietary advanced glycation end products-a risk to human health? A call for an interdisciplinary debate.
    • Henle, T. (2007) Dietary advanced glycation end products-a risk to human health? A call for an interdisciplinary debate. Mol. Nutr. Food Res. 51, 1075-1078
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1075-1078
    • Henle, T.1
  • 66
    • 84878225796 scopus 로고    scopus 로고
    • Digestibility of extruded proteins and metabolic transit of N ε-carboxymethyllysine in rats
    • Alamir, I., Niquet-Leridon, C., Jacolot, P., Rodriguez, C., Orosco, M., Anton, P.M. et al. (2013) Digestibility of extruded proteins and metabolic transit of N ε-carboxymethyllysine in rats. Amino Acids 44, 1441-1449
    • (2013) Amino Acids , vol.44 , pp. 1441-1449
    • Alamir, I.1    Niquet-Leridon, C.2    Jacolot, P.3    Rodriguez, C.4    Orosco, M.5    Anton, P.M.6
  • 67
    • 84960104929 scopus 로고    scopus 로고
    • Dietary advanced glycation end products and risk factors for chronic disease: a systematic review of randomised controlled trials
    • Clarke, R.E., Dordevic, A.L., Tan, S.M., Ryan, L. and Coughlan, M.T. (2016) Dietary advanced glycation end products and risk factors for chronic disease: a systematic review of randomised controlled trials. Nutrients 8, 125
    • (2016) Nutrients , vol.8 , pp. 125
    • Clarke, R.E.1    Dordevic, A.L.2    Tan, S.M.3    Ryan, L.4    Coughlan, M.T.5
  • 69
    • 84955661326 scopus 로고    scopus 로고
    • The low AGE diet: a neglected aspect of clinical nephrology practice
    • Uribarri, J. and He, J.C. (2015) The low AGE diet: a neglected aspect of clinical nephrology practice. Nephron 130, 48-53
    • (2015) Nephron , vol.130 , pp. 48-53
    • Uribarri, J.1    He, J.C.2
  • 71
    • 84893797069 scopus 로고    scopus 로고
    • MicroRNA in diabetic nephropathy: renin angiotensin, aGE/RAGE, and oxidative stress pathway
    • Hagiwara, S., McClelland, A. and Kantharidis, P. (2013) MicroRNA in diabetic nephropathy: renin angiotensin, aGE/RAGE, and oxidative stress pathway. J. Diabetes Res. 2013, 173783
    • (2013) J. Diabetes Res. , vol.2013 , pp. 173783
    • Hagiwara, S.1    McClelland, A.2    Kantharidis, P.3
  • 72
    • 84981169465 scopus 로고    scopus 로고
    • Diabetic kidney disease: a role for advanced glycation end-product receptor 1 (AGE-R1).
    • Zhuang, A. and Forbes, J.M. (2016) Diabetic kidney disease: a role for advanced glycation end-product receptor 1 (AGE-R1). Glycoconj. J. 33, 645-652
    • (2016) Glycoconj. J. , vol.33 , pp. 645-652
    • Zhuang, A.1    Forbes, J.M.2
  • 74
    • 0034947508 scopus 로고    scopus 로고
    • Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
    • Yamamoto, Y., Kato, I., Doi, T., Yonekura, H., Ohashi, S., Takeuchi, M. et al. (2001) Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J. Clin. Invest. 108, 261-268
    • (2001) J. Clin. Invest. , vol.108 , pp. 261-268
    • Yamamoto, Y.1    Kato, I.2    Doi, T.3    Yonekura, H.4    Ohashi, S.5    Takeuchi, M.6
  • 75
    • 0030906581 scopus 로고    scopus 로고
    • Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation
    • Nakamura, S., Makita, Z., Ishikawa, S., Yasumura, K., Fujii, W., Yanagisawa, K. et al. (1997) Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation. Diabetes 46, 895-899
    • (1997) Diabetes , vol.46 , pp. 895-899
    • Nakamura, S.1    Makita, Z.2    Ishikawa, S.3    Yasumura, K.4    Fujii, W.5    Yanagisawa, K.6
  • 76
    • 0141483457 scopus 로고    scopus 로고
    • The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
    • Forbes, J.M., Thallas, V., Thomas, M.C., Founds, H.W., Burns, W.C., Jerums, G. et al. (2003) The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB J. 17, 1762-1764
    • (2003) FASEB J. , vol.17 , pp. 1762-1764
    • Forbes, J.M.1    Thallas, V.2    Thomas, M.C.3    Founds, H.W.4    Burns, W.C.5    Jerums, G.6
  • 78
    • 0031008674 scopus 로고    scopus 로고
    • Advanced glycation end products in serum predict changes in the kidney morphology of patients with insulin-dependent diabetes mellitus
    • Berg, T.J., Bangstad, H.J., Torjesen, P.A., Osterby, R., Bucala, R. and Hanssen, K.F. (1997) Advanced glycation end products in serum predict changes in the kidney morphology of patients with insulin-dependent diabetes mellitus. Metabolism 46, 661-665
    • (1997) Metabolism , vol.46 , pp. 661-665
    • Berg, T.J.1    Bangstad, H.J.2    Torjesen, P.A.3    Osterby, R.4    Bucala, R.5    Hanssen, K.F.6
  • 79
    • 84962439630 scopus 로고    scopus 로고
    • Relationship between levels of advanced glycation end products and their soluble receptor and adverse outcomes in adults with type 2 diabetes
    • Thomas, M.C., Woodward, M., Neal, B., Li, Q., Pickering, R., Marre, M. et al. (2015) Relationship between levels of advanced glycation end products and their soluble receptor and adverse outcomes in adults with type 2 diabetes. Diabetes Care 38, 1891-1897
    • (2015) Diabetes Care , vol.38 , pp. 1891-1897
    • Thomas, M.C.1    Woodward, M.2    Neal, B.3    Li, Q.4    Pickering, R.5    Marre, M.6
  • 80
    • 0027169317 scopus 로고
    • Increased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy
    • Beisswenger, P.J., Moore, L.L., Brinck-Johnsen, T. and Curphey, T.J. (1993) Increased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy. J. Clin. Invest. 92, 212-217
    • (1993) J. Clin. Invest. , vol.92 , pp. 212-217
    • Beisswenger, P.J.1    Moore, L.L.2    Brinck-Johnsen, T.3    Curphey, T.J.4
  • 81
    • 33644698951 scopus 로고    scopus 로고
    • Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes
    • Genuth, S., Sun, W., Cleary, P., Sell, D.R., Dahms, W., Malone, J. et al. (2005) Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes. Diabetes 54, 3103-3111
    • (2005) Diabetes , vol.54 , pp. 3103-3111
    • Genuth, S.1    Sun, W.2    Cleary, P.3    Sell, D.R.4    Dahms, W.5    Malone, J.6
  • 82
    • 10744223527 scopus 로고    scopus 로고
    • Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy
    • Bolton, W.K., Cattran, D.C., Williams, M.E., Adler, S.G., Appel, G.B., Cartwright, K. et al. (2004) Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy. Am. J. Nephrol. 24, 32-40
    • (2004) Am. J. Nephrol. , vol.24 , pp. 32-40
    • Bolton, W.K.1    Cattran, D.C.2    Williams, M.E.3    Adler, S.G.4    Appel, G.B.5    Cartwright, K.6
  • 83
    • 84863654466 scopus 로고    scopus 로고
    • Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy
    • Alkhalaf, A., Kleefstra, N., Groenier, K.H., Bilo, H.J.G., Gans, R.O.B., Heeringa, P. et al. (2012) Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy. PloS One 7, e40427
    • (2012) PloS One , vol.7
    • Alkhalaf, A.1    Kleefstra, N.2    Groenier, K.H.3    Bilo, H.J.G.4    Gans, R.O.B.5    Heeringa, P.6
  • 84
    • 77958158176 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy
    • Alkhalaf, A., Klooster, A., van Oeveren, W., Achenbach, U., Kleefstra, N., Slingerland, R.J. et al. (2010) A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy. Diabetes Care 33, 1598-1601
    • (2010) Diabetes Care , vol.33 , pp. 1598-1601
    • Alkhalaf, A.1    Klooster, A.2    van Oeveren, W.3    Achenbach, U.4    Kleefstra, N.5    Slingerland, R.J.6
  • 85
    • 35548975242 scopus 로고    scopus 로고
    • Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy
    • Williams, M.E., Bolton, W.K., Khalifah, R.G., Degenhardt, T.P., Schotzinger, R.J. and McGill, J.B. (2007) Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy. Am. J. Nephrol. 27, 605-614
    • (2007) Am. J. Nephrol. , vol.27 , pp. 605-614
    • Williams, M.E.1    Bolton, W.K.2    Khalifah, R.G.3    Degenhardt, T.P.4    Schotzinger, R.J.5    McGill, J.B.6
  • 86
    • 0033848466 scopus 로고    scopus 로고
    • Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease
    • Tanji, N., Markowitz, G.S., Fu, C., Kislinger, T., Taguchi, A., Pischetsrieder, M. et al. (2000) Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease. J. Am. Soc. Nephrol. 11, 1656-1666
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 1656-1666
    • Tanji, N.1    Markowitz, G.S.2    Fu, C.3    Kislinger, T.4    Taguchi, A.5    Pischetsrieder, M.6
  • 87
    • 84863893585 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis
    • Martens, H.A., Nienhuis, H.L.A., Gross, S., van der Steege, G., Brouwer, E., Berden, J.H.M. et al. (2012) Receptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis. Lupus 21, 959-968
    • (2012) Lupus , vol.21 , pp. 959-968
    • Martens, H.A.1    Nienhuis, H.L.A.2    Gross, S.3    van der Steege, G.4    Brouwer, E.5    Berden, J.H.M.6
  • 88
    • 0031785582 scopus 로고    scopus 로고
    • Accumulation of carbonyls accelerates the formation of pentosidine, an advanced glycation end product: carbonyl stress in uremia
    • Miyata, T., Ueda, Y., Yamada, Y., Izuhara, Y., Wada, T., Jadoul, M. et al. (1998) Accumulation of carbonyls accelerates the formation of pentosidine, an advanced glycation end product: carbonyl stress in uremia. J. Am. Soc. Nephrol. 9, 2349-2356
    • (1998) J. Am. Soc. Nephrol. , vol.9 , pp. 2349-2356
    • Miyata, T.1    Ueda, Y.2    Yamada, Y.3    Izuhara, Y.4    Wada, T.5    Jadoul, M.6
  • 89
  • 90
    • 84922623834 scopus 로고    scopus 로고
    • Increased accumulation of protein-bound N(e)-(carboxymethyl)lysine in tissues of healthy rats after chronic oral N(e)-(carboxymethyl)lysine
    • Li, M., Zeng, M., He, Z., Zheng, Z., Qin, F., Tao, G. et al. (2015) Increased accumulation of protein-bound N(e)-(carboxymethyl)lysine in tissues of healthy rats after chronic oral N(e)-(carboxymethyl)lysine. J. Agric. Food Chem. 63, 1658-1663
    • (2015) J. Agric. Food Chem. , vol.63 , pp. 1658-1663
    • Li, M.1    Zeng, M.2    He, Z.3    Zheng, Z.4    Qin, F.5    Tao, G.6
  • 91
    • 23744512395 scopus 로고    scopus 로고
    • Renal effects of oral maillard reaction product load in the form of bread crusts in healthy and subtotally nephrectomized rats
    • Sebeková, K., Hofmann, T., Boor, P., Sebeková, K., Ulicná, O., Erbersdobler, H.F. et al. (2005) Renal effects of oral maillard reaction product load in the form of bread crusts in healthy and subtotally nephrectomized rats. Ann. N.Y. Acad. Sci. 1043, 482-491
    • (2005) Ann. N.Y. Acad. Sci. , vol.1043 , pp. 482-491
    • Sebeková, K.1    Hofmann, T.2    Boor, P.3    Sebeková, K.4    Ulicná, O.5    Erbersdobler, H.F.6
  • 92
    • 0035985243 scopus 로고    scopus 로고
    • Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products
    • Zheng, F., He, C., Cai, W., Hattori, M., Steffes, M. and Vlassara, H. (2002) Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products. Diabetes Metab. Res. Rev. 18, 224-237
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. 224-237
    • Zheng, F.1    He, C.2    Cai, W.3    Hattori, M.4    Steffes, M.5    Vlassara, H.6
  • 93
    • 34247547940 scopus 로고    scopus 로고
    • Restricted intake of dietary advanced glycation end products retards renal progression in the remnant kidney model
    • Feng, J.X., Hou, F.F., Liang, M., Wang, G.B., Zhang, X., Li, H.Y. et al. (2007) Restricted intake of dietary advanced glycation end products retards renal progression in the remnant kidney model. Kidney Int. 71, 901-911
    • (2007) Kidney Int. , vol.71 , pp. 901-911
    • Feng, J.X.1    Hou, F.F.2    Liang, M.3    Wang, G.B.4    Zhang, X.5    Li, H.Y.6
  • 94
    • 70449131003 scopus 로고    scopus 로고
    • Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1
    • Vlassara, H., Cai, W., Goodman, S., Pyzik, R., Yong, A., Chen, X. et al. (2009) Protection against loss of innate defenses in adulthood by low advanced glycation end products (AGE) intake: role of the antiinflammatory AGE receptor-1. J. Clin. Endocrinol. Metab. 94, 4483-4491
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 4483-4491
    • Vlassara, H.1    Cai, W.2    Goodman, S.3    Pyzik, R.4    Yong, A.5    Chen, X.6
  • 95
    • 0037369890 scopus 로고    scopus 로고
    • Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients
    • Uribarri, J., Peppa, M., Cai, W., Goldberg, T., Lu, M., He, C. et al. (2003) Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients. J. Am. Soc. Nephrol. 14, 728-731
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 728-731
    • Uribarri, J.1    Peppa, M.2    Cai, W.3    Goldberg, T.4    Lu, M.5    He, C.6
  • 97
    • 27744505416 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation
    • Pala, L., Cresci, B., Manuelli, C., Maggi, E., Yamaguchi, Y.F., Cappugi, P. et al. (2005) Vascular endothelial growth factor receptor-2 and low affinity VEGF binding sites on human glomerular endothelial cells: Biological effects and advanced glycosilation end products modulation. Microvasc. Res. 70, 179-188
    • (2005) Microvasc. Res. , vol.70 , pp. 179-188
    • Pala, L.1    Cresci, B.2    Manuelli, C.3    Maggi, E.4    Yamaguchi, Y.F.5    Cappugi, P.6
  • 98
    • 79954617011 scopus 로고    scopus 로고
    • Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells
    • Matsui, T., Nishino, Y., Maeda, S., Takeuchi, M. and Yamagishi, S. (2011) Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells. Microvasc. Res. 81, 269-273
    • (2011) Microvasc. Res. , vol.81 , pp. 269-273
    • Matsui, T.1    Nishino, Y.2    Maeda, S.3    Takeuchi, M.4    Yamagishi, S.5
  • 99
    • 84924692264 scopus 로고    scopus 로고
    • Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity
    • Luo, P., Peng, H., Li, C., Ye, Z., Tang, H., Tang, Y. et al. (2015) Advanced glycation end products induce glomerular endothelial cell hyperpermeability by upregulating matrix metalloproteinase activity. Mol. Med. Rep. 11, 4447-4453
    • (2015) Mol. Med. Rep. , vol.11 , pp. 4447-4453
    • Luo, P.1    Peng, H.2    Li, C.3    Ye, Z.4    Tang, H.5    Tang, Y.6
  • 100
    • 84924705831 scopus 로고    scopus 로고
    • Advanced glycation end-products affect the cytoskeletal structure of rat glomerular endothelial cells via the Ras-related C3 botulinum toxin substrate 1 signaling pathway
    • Lan, L., Han, Y., Ren, W., Jiang, J., Wang, P. and Hu, Z. (2015) Advanced glycation end-products affect the cytoskeletal structure of rat glomerular endothelial cells via the Ras-related C3 botulinum toxin substrate 1 signaling pathway. Mol. Med. Rep. 11, 4321-4326
    • (2015) Mol. Med. Rep. , vol.11 , pp. 4321-4326
    • Lan, L.1    Han, Y.2    Ren, W.3    Jiang, J.4    Wang, P.5    Hu, Z.6
  • 101
    • 46849090102 scopus 로고    scopus 로고
    • Advanced glycation end-products induce cell cycle arrest and hypertrophy in podocytes
    • Rüster, C., Bondeva, T., Franke, S., Förster, M. and Wolf, G. (2008) Advanced glycation end-products induce cell cycle arrest and hypertrophy in podocytes. Nephrol. Dial. Transplant. 23, 2179-2191
    • (2008) Nephrol. Dial. Transplant. , vol.23 , pp. 2179-2191
    • Rüster, C.1    Bondeva, T.2    Franke, S.3    Förster, M.4    Wolf, G.5
  • 102
    • 34948906839 scopus 로고    scopus 로고
    • Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor
    • Chuang, P.Y., Yu, Q., Fang, W., Uribarri, J. and He, J.C. (2007) Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor. Kidney Int. 72, 965-976
    • (2007) Kidney Int. , vol.72 , pp. 965-976
    • Chuang, P.Y.1    Yu, Q.2    Fang, W.3    Uribarri, J.4    He, J.C.5
  • 103
    • 84939469548 scopus 로고    scopus 로고
    • Advanced oxidation protein products induce apoptosis in podocytes through induction of endoplasmic reticulum stress
    • Rong, G., Tang, X., Guo, T., Duan, N., Wang, Y., Yang, L. et al. (2015) Advanced oxidation protein products induce apoptosis in podocytes through induction of endoplasmic reticulum stress. J. Physiol. Biochem. 71, 455-470
    • (2015) J. Physiol. Biochem. , vol.71 , pp. 455-470
    • Rong, G.1    Tang, X.2    Guo, T.3    Duan, N.4    Wang, Y.5    Yang, L.6
  • 104
    • 84866419120 scopus 로고    scopus 로고
    • The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis
    • Zhou, L.L., Cao, W., Xie, C., Tian, J., Zhou, Z., Zhou, Q. et al. (2012) The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis. Kidney Int. 82, 759-770
    • (2012) Kidney Int. , vol.82 , pp. 759-770
    • Zhou, L.L.1    Cao, W.2    Xie, C.3    Tian, J.4    Zhou, Z.5    Zhou, Q.6
  • 105
    • 0345505674 scopus 로고    scopus 로고
    • Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II
    • Doublier, S., Salvidio, G., Lupia, E., Ruotsalainen, V., Verzola, D., Deferrari, G. et al. (2003) Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes 52, 1023-1030
    • (2003) Diabetes , vol.52 , pp. 1023-1030
    • Doublier, S.1    Salvidio, G.2    Lupia, E.3    Ruotsalainen, V.4    Verzola, D.5    Deferrari, G.6
  • 106
    • 84872029442 scopus 로고    scopus 로고
    • Advanced glycation end-products activate the renin-angiotensin system through the RAGE/PI3-K signaling pathway in podocytes
    • Cheng, C.L., Tang, Y., Zheng, Z., Liu, X., Ye, Z.C., Wang, C. et al. (2012) Advanced glycation end-products activate the renin-angiotensin system through the RAGE/PI3-K signaling pathway in podocytes. Clin. Invest. Med. 35, E282
    • (2012) Clin. Invest. Med. , vol.35 , pp. E282
    • Cheng, C.L.1    Tang, Y.2    Zheng, Z.3    Liu, X.4    Ye, Z.C.5    Wang, C.6
  • 107
    • 33749120097 scopus 로고    scopus 로고
    • High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells
    • Ha, T.-S. (2006) High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells. Nephrology (Carlton) 11, 435-441
    • (2006) Nephrology (Carlton) , vol.11 , pp. 435-441
    • Ha, T.-S.1
  • 109
    • 80053380547 scopus 로고    scopus 로고
    • Advanced glycation end products inhibit adhesion ability of differentiated podocytes in a neuropilin-1-dependent manner
    • Bondeva, T., Wojciech, S. and Wolf, G. (2011) Advanced glycation end products inhibit adhesion ability of differentiated podocytes in a neuropilin-1-dependent manner. Am. J. Physiol. Renal. Physiol. 301, F852-F870
    • (2011) Am. J. Physiol. Renal. Physiol. , vol.301 , pp. F852-F870
    • Bondeva, T.1    Wojciech, S.2    Wolf, G.3
  • 110
    • 84951778548 scopus 로고    scopus 로고
    • Ezrin contributes to impaired podocyte migration and adhesion caused by advanced glycation end products
    • McRobert, E.A. and Bach, L.A. (2016) Ezrin contributes to impaired podocyte migration and adhesion caused by advanced glycation end products. Nephrology (Carlton) 21, 13-20
    • (2016) Nephrology (Carlton) , vol.21 , pp. 13-20
    • McRobert, E.A.1    Bach, L.A.2
  • 113
    • 84947081161 scopus 로고    scopus 로고
    • Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus
    • Kumar, P.A., Welsh, G.I., Raghu, G., Menon, R.K., Saleem, M.A. and Reddy, G.B. (2016) Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus. Arch. Biochem. Biophys. 590, 10-19
    • (2016) Arch. Biochem. Biophys. , vol.590 , pp. 10-19
    • Kumar, P.A.1    Welsh, G.I.2    Raghu, G.3    Menon, R.K.4    Saleem, M.A.5    Reddy, G.B.6
  • 115
    • 9444266461 scopus 로고    scopus 로고
    • RAGE- and TGF-beta receptor-mediated signals converge on STAT5 and p21waf to control cell-cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy
    • Brizzi, M.F., Dentelli, P., Rosso, A., Calvi, C., Gambino, R., Cassader, M. et al. (2004) RAGE- and TGF-beta receptor-mediated signals converge on STAT5 and p21waf to control cell-cycle progression of mesangial cells: a possible role in the development and progression of diabetic nephropathy. FASEB J. 18, 1249-1251
    • (2004) FASEB J. , vol.18 , pp. 1249-1251
    • Brizzi, M.F.1    Dentelli, P.2    Rosso, A.3    Calvi, C.4    Gambino, R.5    Cassader, M.6
  • 116
    • 0037036345 scopus 로고    scopus 로고
    • Advanced glycation end product-induced apoptosis and overexpression of vascular endothelial growth factor and monocyte chemoattractant protein-1 in human-cultured mesangial cells
    • Yamagishi, S., Inagaki, Y., Okamoto, T., Amano, S., Koga, K., Takeuchi, M. et al. (2002) Advanced glycation end product-induced apoptosis and overexpression of vascular endothelial growth factor and monocyte chemoattractant protein-1 in human-cultured mesangial cells. J. Biol. Chem. 277, 20309-20315
    • (2002) J. Biol. Chem. , vol.277 , pp. 20309-20315
    • Yamagishi, S.1    Inagaki, Y.2    Okamoto, T.3    Amano, S.4    Koga, K.5    Takeuchi, M.6
  • 117
    • 84884673379 scopus 로고    scopus 로고
    • NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes
    • Gao, L., Huang, W. and Li, J. (2013) NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. Mol. Cell Biochem. 382, 185-191
    • (2013) Mol. Cell Biochem. , vol.382 , pp. 185-191
    • Gao, L.1    Huang, W.2    Li, J.3
  • 118
    • 84908571333 scopus 로고    scopus 로고
    • Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-ß1 in rat glomerular messangial cells
    • Huang, K., Chen, C., Hao, J., Huang, J., Wang, S., Liu, P. et al. (2015) Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-ß1 in rat glomerular messangial cells. Mol. Cell Endocrinol. 399, 178-189
    • (2015) Mol. Cell Endocrinol. , vol.399 , pp. 178-189
    • Huang, K.1    Chen, C.2    Hao, J.3    Huang, J.4    Wang, S.5    Liu, P.6
  • 119
    • 80054966317 scopus 로고    scopus 로고
    • CCN-2 is up-regulated by and mediates effects of matrix bound advanced glycated end-products in human renal mesangial cells
    • Wang, X., McLennan, S.V. and Twigg, S.M. (2011) CCN-2 is up-regulated by and mediates effects of matrix bound advanced glycated end-products in human renal mesangial cells. J. Cell Commun. Signal. 5, 193-200
    • (2011) J. Cell Commun. Signal. , vol.5 , pp. 193-200
    • Wang, X.1    McLennan, S.V.2    Twigg, S.M.3
  • 120
    • 79960053947 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro
    • Yuan, Y., Zhao, L., Chen, Y., Moorhead, J.F., Varghese, Z., Powis, S.H. et al. (2011) Advanced glycation end products (AGEs) increase human mesangial foam cell formation by increasing Golgi SCAP glycosylation in vitro. Am. J. Physiol. Renal. Physiol. 301, F236-F243
    • (2011) Am. J. Physiol. Renal. Physiol. , vol.301 , pp. F236-F243
    • Yuan, Y.1    Zhao, L.2    Chen, Y.3    Moorhead, J.F.4    Varghese, Z.5    Powis, S.H.6
  • 121
    • 0032731318 scopus 로고    scopus 로고
    • The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury
    • Gilbert, R.E. and Cooper, M.E. (1999) The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury. Kidney Int. 56, 1627-1637
    • (1999) Kidney Int. , vol.56 , pp. 1627-1637
    • Gilbert, R.E.1    Cooper, M.E.2
  • 122
    • 84864601012 scopus 로고    scopus 로고
    • The pathogenic role of the renal proximal tubular cell in diabetic nephropathy
    • Tang, S.C.W. and Lai, K.N. (2012) The pathogenic role of the renal proximal tubular cell in diabetic nephropathy. Nephrol. Dial. Transplant. 27, 3049-3056
    • (2012) Nephrol. Dial. Transplant. , vol.27 , pp. 3049-3056
    • Tang, S.C.W.1    Lai, K.N.2
  • 123
    • 36248956180 scopus 로고    scopus 로고
    • Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin
    • Ozdemir, A.M., Hopfer, U., Rosca, M.V., Fan, X.-J., Monnier, V.M. and Weiss, M.F. (2008) Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin. Am. J. Nephrol. 28, 14-24
    • (2008) Am. J. Nephrol. , vol.28 , pp. 14-24
    • Ozdemir, A.M.1    Hopfer, U.2    Rosca, M.V.3    Fan, X.-J.4    Monnier, V.M.5    Weiss, M.F.6
  • 124
    • 84882766895 scopus 로고    scopus 로고
    • Uptake of advanced glycation end products by proximal tubule epithelial cells via macropinocytosis
    • Gallicchio, M.A. and Bach, L.A. (2013) Uptake of advanced glycation end products by proximal tubule epithelial cells via macropinocytosis. Biochim. Biophys. Acta 1833, 2922-2932
    • (2013) Biochim. Biophys. Acta , vol.1833 , pp. 2922-2932
    • Gallicchio, M.A.1    Bach, L.A.2
  • 125
    • 1642336325 scopus 로고    scopus 로고
    • Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway
    • Li, J.H., Wang, W., Huang, X.R., Oldfield, M., Schmidt, A.M., Cooper, M.E. et al. (2004) Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am. J. Pathol. 164, 1389-1397
    • (2004) Am. J. Pathol. , vol.164 , pp. 1389-1397
    • Li, J.H.1    Wang, W.2    Huang, X.R.3    Oldfield, M.4    Schmidt, A.M.5    Cooper, M.E.6
  • 126
    • 0035661067 scopus 로고    scopus 로고
    • Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE).
    • Oldfield, M.D., Bach, L.A., Forbes, J.M., Nikolic-Paterson, D., McRobert, A., Thallas, V. et al. (2001) Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J. Clin. Invest. 108, 1853-1863
    • (2001) J. Clin. Invest. , vol.108 , pp. 1853-1863
    • Oldfield, M.D.1    Bach, L.A.2    Forbes, J.M.3    Nikolic-Paterson, D.4    McRobert, A.5    Thallas, V.6
  • 127
    • 84928719808 scopus 로고    scopus 로고
    • HMGB1 enhances the AGE-induced expression of CTGF and TGF-ß via RAGE-dependent signaling in renal tubular epithelial cells
    • Cheng, M., Liu, H., Zhang, D., Liu, Y., Wang, C., Liu, F. et al. (2015) HMGB1 enhances the AGE-induced expression of CTGF and TGF-β via RAGE-dependent signaling in renal tubular epithelial cells. Am. J. Nephrol. 41, 257-266
    • (2015) Am. J. Nephrol. , vol.41 , pp. 257-266
    • Cheng, M.1    Liu, H.2    Zhang, D.3    Liu, Y.4    Wang, C.5    Liu, F.6
  • 128
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: sparking the development of diabetic vascular injury
    • Goldin, A., Beckman, J.A., Schmidt, A.M. and Creager, M.A. (2006) Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation. 114, 597-605
    • (2006) Circulation. , vol.114 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 129
    • 33745683623 scopus 로고    scopus 로고
    • Oxidative stress, advanced glycation end product, and coronary artery calcification in hemodialysis patients
    • Taki, K., Takayama, F., Tsuruta, Y. and Niwa, T. (2006) Oxidative stress, advanced glycation end product, and coronary artery calcification in hemodialysis patients. Kidney Int. 70, 218-224
    • (2006) Kidney Int. , vol.70 , pp. 218-224
    • Taki, K.1    Takayama, F.2    Tsuruta, Y.3    Niwa, T.4
  • 130
    • 79952985492 scopus 로고    scopus 로고
    • Advanced glycation end products, carotid atherosclerosis, and circulating endothelial progenitor cells in patients with end-stage renal disease
    • Ueno, H., Koyama, H., Fukumoto, S., Tanaka, S., Shoji, T., Shoji, T. et al. (2011) Advanced glycation end products, carotid atherosclerosis, and circulating endothelial progenitor cells in patients with end-stage renal disease. Metabolism 60, 453-459
    • (2011) Metabolism , vol.60 , pp. 453-459
    • Ueno, H.1    Koyama, H.2    Fukumoto, S.3    Tanaka, S.4    Shoji, T.5    Shoji, T.6
  • 131
    • 84865376010 scopus 로고    scopus 로고
    • Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis
    • Jiang, J., Chen, P., Chen, J., Yu, X., Xie, D., Mei, C. et al. (2012) Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis. Atherosclerosis 224, 187-194
    • (2012) Atherosclerosis , vol.224 , pp. 187-194
    • Jiang, J.1    Chen, P.2    Chen, J.3    Yu, X.4    Xie, D.5    Mei, C.6
  • 132
    • 84860348119 scopus 로고    scopus 로고
    • Molecular basis of arterial stiffening: role of glycation-a mini-review
    • Sell, D.R. and Monnier, V,M. (2012) Molecular basis of arterial stiffening: role of glycation-a mini-review. Gerontology 58, 227-237
    • (2012) Gerontology , vol.58 , pp. 227-237
    • Sell, D.R.1    Monnier, V.M.2
  • 133
    • 0027956982 scopus 로고
    • Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency
    • Bucala, R., Makita, Z., Vega, G., Grundy, S., Koschinsky, T., Cerami, A. et al. (1994) Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency. Proc. Natl. Acad. Sci. U.S.A. 91, 9441-9445
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 9441-9445
    • Bucala, R.1    Makita, Z.2    Vega, G.3    Grundy, S.4    Koschinsky, T.5    Cerami, A.6
  • 135
    • 84976321291 scopus 로고    scopus 로고
    • Implication of advanced glycation end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions
    • Neviere, R., Yu, Y., Wang, L., Tessier, F. and Boulanger, E. (2016) Implication of advanced glycation end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions. Glycoconj. J. 33, 607-617
    • (2016) Glycoconj. J. , vol.33 , pp. 607-617
    • Neviere, R.1    Yu, Y.2    Wang, L.3    Tessier, F.4    Boulanger, E.5
  • 136
    • 84908206562 scopus 로고    scopus 로고
    • Lifestyle and advanced glycation end products (AGEs) burden: its relevance to healthy aging
    • Prasad, C., Imrhan, V., Marotta, F., Juma, S. and Vijayagopal, P. (2014) Lifestyle and advanced glycation end products (AGEs) burden: its relevance to healthy aging. Aging Dis. 5, 212-217
    • (2014) Aging Dis. , vol.5 , pp. 212-217
    • Prasad, C.1    Imrhan, V.2    Marotta, F.3    Juma, S.4    Vijayagopal, P.5
  • 137
    • 84886953422 scopus 로고    scopus 로고
    • Protein glycation during aging and in cardiovascular disease
    • Simm, A. (2013) Protein glycation during aging and in cardiovascular disease. J. Proteomics 92, 248-259
    • (2013) J. Proteomics , vol.92 , pp. 248-259
    • Simm, A.1
  • 138
    • 84899119923 scopus 로고    scopus 로고
    • Advanced glycation end products: role in pathology of diabetic cardiomyopathy
    • Bodiga, V.L., Eda, S.R. and Bodiga, S. (2014) Advanced glycation end products: role in pathology of diabetic cardiomyopathy. Heart Fail. Rev. 19, 49-63
    • (2014) Heart Fail. Rev. , vol.19 , pp. 49-63
    • Bodiga, V.L.1    Eda, S.R.2    Bodiga, S.3
  • 140
    • 0027718105 scopus 로고
    • Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
    • Brett, J., Schmidt, A.M., Yan, S.D., Zou, Y.S., Weidman, E., Pinsky, D. et al. (1993) Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am. J. Pathol. 143, 1699-1712
    • (1993) Am. J. Pathol. , vol.143 , pp. 1699-1712
    • Brett, J.1    Schmidt, A.M.2    Yan, S.D.3    Zou, Y.S.4    Weidman, E.5    Pinsky, D.6
  • 142
    • 0029946123 scopus 로고    scopus 로고
    • Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats
    • Norton, G.R., Candy, G. and Woodiwiss, A.J. (1996) Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats. Circulation 93, 1905-1912
    • (1996) Circulation , vol.93 , pp. 1905-1912
    • Norton, G.R.1    Candy, G.2    Woodiwiss, A.J.3
  • 144
    • 84903698784 scopus 로고    scopus 로고
    • Role of AGEs-RAGE system in cardiovascular disease
    • Fukami, K., Yamagishi, S.-I. and Okuda, S. (2014) Role of AGEs-RAGE system in cardiovascular disease. Curr. Pharm. Des. 20, 2395-2402
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 2395-2402
    • Fukami, K.1    Yamagishi, S.-I.2    Okuda, S.3
  • 146
    • 84864885117 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) and implications for the pathophysiology of heart failure
    • Ramasamy, R. and Schmidt, A.M. (2012) Receptor for advanced glycation end products (RAGE) and implications for the pathophysiology of heart failure. Curr. Heart Fail. Rep. 9, 107-116
    • (2012) Curr. Heart Fail. Rep. , vol.9 , pp. 107-116
    • Ramasamy, R.1    Schmidt, A.M.2
  • 147
    • 84885955952 scopus 로고    scopus 로고
    • Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease
    • Ward, M.S., Fortheringham, A.K., Cooper, M.E. and Forbes, J.M. (2013) Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease. Curr. Opin. Pharmacol. 13, 654-661
    • (2013) Curr. Opin. Pharmacol. , vol.13 , pp. 654-661
    • Ward, M.S.1    Fortheringham, A.K.2    Cooper, M.E.3    Forbes, J.M.4
  • 148
    • 65349167787 scopus 로고    scopus 로고
    • The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease
    • Yan, S.F., Ramasamy, R. and Schmidt, A.M. (2009) The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease. Expert Rev. Mol. Med. 11, e9
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Yan, S.F.1    Ramasamy, R.2    Schmidt, A.M.3
  • 149
    • 67650096803 scopus 로고    scopus 로고
    • Blockage of receptor for advanced glycation end products prevents development of cardiac dysfunction in db/db type 2 diabetic mice
    • Nielsen, J.M., Kristiansen, S.B., Nørregaard, R., Andersen, C.L., Denner, L., Nielsen, T.T. et al. (2009) Blockage of receptor for advanced glycation end products prevents development of cardiac dysfunction in db/db type 2 diabetic mice. Eur. J. Heart Fail. 11, 638-647
    • (2009) Eur. J. Heart Fail. , vol.11 , pp. 638-647
    • Nielsen, J.M.1    Kristiansen, S.B.2    Nørregaard, R.3    Andersen, C.L.4    Denner, L.5    Nielsen, T.T.6
  • 150
    • 84964658330 scopus 로고    scopus 로고
    • Cross-linking versus RAGE: How do high molecular weight advanced glycation products induce cardiac dysfunction
    • Deluyker, D., Ferferieva, V., Noben, J.-P., Swennen, Q., Bronckaers, A., Lambrichts, I. et al. (2016) Cross-linking versus RAGE: How do high molecular weight advanced glycation products induce cardiac dysfunction. Int. J. Cardiol. 210, 100-108
    • (2016) Int. J. Cardiol. , vol.210 , pp. 100-108
    • Deluyker, D.1    Ferferieva, V.2    Noben, J.-P.3    Swennen, Q.4    Bronckaers, A.5    Lambrichts, I.6
  • 151
    • 0034646372 scopus 로고    scopus 로고
    • An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness
    • Asif, M., Egan, J., Vasan, S., Jyothirmayi, G.N., Masurekar, M.R., Lopez, S. et al. (2000) An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness. Proc. Natl. Acad. Sci. U.S.A. 97, 2809-2813
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 2809-2813
    • Asif, M.1    Egan, J.2    Vasan, S.3    Jyothirmayi, G.N.4    Masurekar, M.R.5    Lopez, S.6
  • 152
    • 37349080234 scopus 로고    scopus 로고
    • Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension
    • van Heerebeek, L., Hamdani, N., Handoko, M.L., Falcao-Pires, I., Musters, R.J., Kupreishvili, K. et al. (2008) Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation 117, 43-51
    • (2008) Circulation , vol.117 , pp. 43-51
    • van Heerebeek, L.1    Hamdani, N.2    Handoko, M.L.3    Falcao-Pires, I.4    Musters, R.J.5    Kupreishvili, K.6
  • 153
    • 0032989116 scopus 로고    scopus 로고
    • Effects of glucose intolerance on myocardial function and collagen-linked glycation
    • Avendano, G.F., Agarwal, R.K., Bashey, R.I., Lyons, M.M., Soni, B.J., Jyothirmayi, G.N. et al. (1999) Effects of glucose intolerance on myocardial function and collagen-linked glycation. Diabetes 48, 1443-1447
    • (1999) Diabetes , vol.48 , pp. 1443-1447
    • Avendano, G.F.1    Agarwal, R.K.2    Bashey, R.I.3    Lyons, M.M.4    Soni, B.J.5    Jyothirmayi, G.N.6
  • 154
    • 0035970120 scopus 로고    scopus 로고
    • A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys
    • Vaitkevicius, P.V., Lane, M., Spurgeon, H., Ingram, D.K., Roth, G.S., Egan, J.J. et al. (2001) A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc. Natl. Acad. Sci. U.S.A. 98, 1171-1175
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 1171-1175
    • Vaitkevicius, P.V.1    Lane, M.2    Spurgeon, H.3    Ingram, D.K.4    Roth, G.S.5    Egan, J.J.6
  • 155
    • 4143091435 scopus 로고    scopus 로고
    • Aminoguanidine prevents age-related deterioration in left ventricular-arterial coupling in Fisher 344 rats
    • Chang, K.-C., Hsu, K.-L., Chou, T.-F., Lo, H.-M. and Tseng, Y.-Z. (2004) Aminoguanidine prevents age-related deterioration in left ventricular-arterial coupling in Fisher 344 rats. Br. J. Pharmacol. 142, 1099-1104
    • (2004) Br. J. Pharmacol. , vol.142 , pp. 1099-1104
    • Chang, K.-C.1    Hsu, K.-L.2    Chou, T.-F.3    Lo, H.-M.4    Tseng, Y.-Z.5
  • 156
    • 36248989151 scopus 로고    scopus 로고
    • Advanced glycation end-products (AGEs) and heart failure: pathophysiology and clinical implications
    • Hartog, J.W.L., Voors, A.A., Bakker, S.J.L., Smit, A.J. and van Veldhuisen, D.J. (2007) Advanced glycation end-products (AGEs) and heart failure: pathophysiology and clinical implications. Eur. J. Heart Fail. 9, 1146-1155
    • (2007) Eur. J. Heart Fail. , vol.9 , pp. 1146-1155
    • Hartog, J.W.L.1    Voors, A.A.2    Bakker, S.J.L.3    Smit, A.J.4    van Veldhuisen, D.J.5
  • 159
    • 80052851550 scopus 로고    scopus 로고
    • Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease
    • Campbell, D.J., Somaratne, J.B., Jenkins, A.J., Prior, D.L., Yii, M., Kenny, J.F. et al. (2011) Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease. Cardiovasc. Diabetol. 10, 80
    • (2011) Cardiovasc. Diabetol. , vol.10 , pp. 80
    • Campbell, D.J.1    Somaratne, J.B.2    Jenkins, A.J.3    Prior, D.L.4    Yii, M.5    Kenny, J.F.6
  • 160
    • 77954212461 scopus 로고    scopus 로고
    • Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium
    • Donaldson, C., Taatjes, D.J., Zile, M., Palmer, B., VanBuren, P., Spinale, F. et al. (2010) Combined immunoelectron microscopic and computer-assisted image analyses to detect advanced glycation end-products in human myocardium. Histochem. Cell Biol. 134, 23-30
    • (2010) Histochem. Cell Biol. , vol.134 , pp. 23-30
    • Donaldson, C.1    Taatjes, D.J.2    Zile, M.3    Palmer, B.4    VanBuren, P.5    Spinale, F.6
  • 161
    • 84863543331 scopus 로고    scopus 로고
    • Advanced glycation end product accumulation in the cardiomyocytes of heart failure patients with and without diabetes
    • Nozyński, J., Zakliczyński, M., Konecka-Mrowka, D., Zielinska, T., Zakliczynska, H., Nikiel, B. et al. (2012) Advanced glycation end product accumulation in the cardiomyocytes of heart failure patients with and without diabetes. Ann. Transplant. 17, 53-61
    • (2012) Ann. Transplant. , vol.17 , pp. 53-61
    • Nozyński, J.1    Zakliczyński, M.2    Konecka-Mrowka, D.3    Zielinska, T.4    Zakliczynska, H.5    Nikiel, B.6
  • 162
    • 79951712789 scopus 로고    scopus 로고
    • Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study
    • Nin, J.W., Jorsal, A., Ferreira, I., Schalkwijk, C.G., Prins, M.H., Parving, H.-H. et al. (2011) Higher plasma levels of advanced glycation end products are associated with incident cardiovascular disease and all-cause mortality in type 1 diabetes: a 12-year follow-up study. Diabetes Care 34, 442-447
    • (2011) Diabetes Care , vol.34 , pp. 442-447
    • Nin, J.W.1    Jorsal, A.2    Ferreira, I.3    Schalkwijk, C.G.4    Prins, M.H.5    Parving, H.-H.6
  • 163
    • 34249931268 scopus 로고    scopus 로고
    • Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study
    • Kilhovd, B.K., Juutilainen, A., Lehto, S., Rönnemaa, T., Torjesen, P.A., Hanssen, K.F. et al. (2007) Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study. Diabetologia 50, 1409-1417
    • (2007) Diabetologia , vol.50 , pp. 1409-1417
    • Kilhovd, B.K.1    Juutilainen, A.2    Lehto, S.3    Rönnemaa, T.4    Torjesen, P.A.5    Hanssen, K.F.6
  • 164
    • 70350425792 scopus 로고    scopus 로고
    • Plasma carboxymethyl-lysine, an advanced glycation end product, and all-cause and cardiovascular disease mortality in older community-dwelling adults
    • Semba, R.D., Bandinelli, S., Sun, K., Guralnik, J.M. and Ferrucci, L. (2009) Plasma carboxymethyl-lysine, an advanced glycation end product, and all-cause and cardiovascular disease mortality in older community-dwelling adults. J. Am. Geriatr. Soc. 57, 1874-1880
    • (2009) J. Am. Geriatr. Soc. , vol.57 , pp. 1874-1880
    • Semba, R.D.1    Bandinelli, S.2    Sun, K.3    Guralnik, J.M.4    Ferrucci, L.5
  • 165
    • 84957881493 scopus 로고    scopus 로고
    • Skin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes
    • Sell, D.R., Sun, W., Gao, X., Strauch, C., Lachin, J.M., Cleary, P.A. et al. (2016) Skin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes. Cardiovasc. Diabetol. 15, 30
    • (2016) Cardiovasc. Diabetol. , vol.15 , pp. 30
    • Sell, D.R.1    Sun, W.2    Gao, X.3    Strauch, C.4    Lachin, J.M.5    Cleary, P.A.6
  • 166
    • 49549110731 scopus 로고    scopus 로고
    • Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients
    • Hartog, J.W.L., Hummel, Y.M., Voors, A.A., Schalkwijk, C.G., Miyata, T., Huisman, R.M. et al. (2008) Skin-autofluorescence, a measure of tissue advanced glycation end-products (AGEs), is related to diastolic function in dialysis patients. J. Card. Fail. 14, 596-602
    • (2008) J. Card. Fail. , vol.14 , pp. 596-602
    • Hartog, J.W.L.1    Hummel, Y.M.2    Voors, A.A.3    Schalkwijk, C.G.4    Miyata, T.5    Huisman, R.M.6
  • 168
    • 48749126012 scopus 로고    scopus 로고
    • Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan
    • Cai, W., He, J.C., Zhu, L., Chen, X., Zheng, F., Striker, G.E. et al. (2008) Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan. Am. J. Pathol. 173, 327-336
    • (2008) Am. J. Pathol. , vol.173 , pp. 327-336
    • Cai, W.1    He, J.C.2    Zhu, L.3    Chen, X.4    Zheng, F.5    Striker, G.E.6
  • 169
    • 77950898257 scopus 로고    scopus 로고
    • The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
    • Yan, S.F., Ramasamy, R. and Schmidt, A.M. (2010) The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circ. Res. 106, 842-853
    • (2010) Circ. Res. , vol.106 , pp. 842-853
    • Yan, S.F.1    Ramasamy, R.2    Schmidt, A.M.3
  • 170
    • 84886314922 scopus 로고    scopus 로고
    • Perspectives on RAGE signaling and its role in cardiovascular disease.
    • Cohen, M.M. (2013) Perspectives on RAGE signaling and its role in cardiovascular disease. Am. J. Med. Genet. A 161A, 2750-2755
    • (2013) Am. J. Med. Genet. , vol.161 , pp. 2750-2755
    • Cohen, M.M.1
  • 171
    • 72949084201 scopus 로고    scopus 로고
    • Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy
    • Ma, H., Li, S.-Y., Xu, P., Babcock, S.A., Dolence, E.K., Brownlee, M. et al. (2009) Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy. J. Cell Mol. Med. 13, 1751-1764
    • (2009) J. Cell Mol. Med. , vol.13 , pp. 1751-1764
    • Ma, H.1    Li, S.-Y.2    Xu, P.3    Babcock, S.A.4    Dolence, E.K.5    Brownlee, M.6
  • 172
    • 84897501364 scopus 로고    scopus 로고
    • Advanced glycation end-products impair Na+ /K+ -ATPase activity in diabetic cardiomyopathy: role of the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway
    • Yuan, Q., Zhou, Q.-Y., Liu, D., Yu, L., Zhan, L., Li, X.-J. et al. (2014) Advanced glycation end-products impair Na+ /K+ -ATPase activity in diabetic cardiomyopathy: role of the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway. Clin. Exp. Pharmacol. Physiol. 41, 127-133
    • (2014) Clin. Exp. Pharmacol. Physiol. , vol.41 , pp. 127-133
    • Yuan, Q.1    Zhou, Q.-Y.2    Liu, D.3    Yu, L.4    Zhan, L.5    Li, X.-J.6
  • 173
    • 33846785483 scopus 로고    scopus 로고
    • Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes
    • Li, S.-Y., Sigmon, V.K., Babcock, S.A. and Ren, J. (2007) Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes. Life Sci. 80, 1051-1056
    • (2007) Life Sci. , vol.80 , pp. 1051-1056
    • Li, S.-Y.1    Sigmon, V.K.2    Babcock, S.A.3    Ren, J.4
  • 174
    • 84885153340 scopus 로고    scopus 로고
    • Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond
    • Daffu, G., del Pozo, C.H., O'Shea, K.M., Ananthakrishnan, R., Ramasamy, R. and Schmidt, A.M. (2013) Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond. Int. J. Mol. Sci. 14, 19891-1910
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 19891-19910
    • Daffu, G.1    del Pozo, C.H.2    O'Shea, K.M.3    Ananthakrishnan, R.4    Ramasamy, R.5    Schmidt, A.M.6
  • 175
    • 80053427168 scopus 로고    scopus 로고
    • Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy
    • Diguet, N., Mallat, Y., Ladouce, R., Clodic, G., Prola, A., Tritsch, E. et al. (2011) Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy. J. Biol. Chem. 286, 35007-35019
    • (2011) J. Biol. Chem. , vol.286 , pp. 35007-35019
    • Diguet, N.1    Mallat, Y.2    Ladouce, R.3    Clodic, G.4    Prola, A.5    Tritsch, E.6
  • 176
    • 84935513713 scopus 로고    scopus 로고
    • Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner
    • Nelson, M.B., Swensen, A.C., Winden, D.R., Bodine, J.S., Bikman, B.T. and Reynolds, P.R. (2015) Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner. Am. J. Physiol. Heart Circ. Physiol. 309, H63-H69
    • (2015) Am. J. Physiol. Heart Circ. Physiol. , vol.309 , pp. H63-H69
    • Nelson, M.B.1    Swensen, A.C.2    Winden, D.R.3    Bodine, J.S.4    Bikman, B.T.5    Reynolds, P.R.6
  • 177
    • 84864244458 scopus 로고    scopus 로고
    • Catalase, a target of glycation damage in rat liver mitochondria with aging
    • Bakala, H., Hamelin, M., Mary, J., Borot-Laloi, C. and Friguet, B. (2012) Catalase, a target of glycation damage in rat liver mitochondria with aging. Biochim. Biophys. Acta 1822, 1527-1534
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1527-1534
    • Bakala, H.1    Hamelin, M.2    Mary, J.3    Borot-Laloi, C.4    Friguet, B.5
  • 178
    • 84882753352 scopus 로고    scopus 로고
    • Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver
    • Bakala, H., Ladouce, R., Baraibar, M.A. and Friguet, B. (2013) Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver. Biochim. Biophys. Acta 1832, 2057-2067
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 2057-2067
    • Bakala, H.1    Ladouce, R.2    Baraibar, M.A.3    Friguet, B.4
  • 179
    • 84947230056 scopus 로고    scopus 로고
    • Ne-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from ß-cells
    • Lo, M.-C., Chen, M.-H., Lee, W.-S., Lu, C.-I., Chang, C.-R., Kao, S.-H. et al. (2015) Ne-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from ß-cells. Am. J. Physiol. Endocrinol. Metab. 309, E829E-E839
    • (2015) Am. J. Physiol. Endocrinol. Metab. , vol.309 , pp. E829E-E839
    • Lo, M.-C.1    Chen, M.-H.2    Lee, W.-S.3    Lu, C.-I.4    Chang, C.-R.5    Kao, S.-H.6
  • 180
    • 84934441687 scopus 로고    scopus 로고
    • Mitochondrial dynamism and heart disease: changing shape and shaping change
    • Dorn, G.W. (2015) Mitochondrial dynamism and heart disease: changing shape and shaping change. EMBO Mol. Med. 7, 865-877
    • (2015) EMBO Mol. Med. , vol.7 , pp. 865-877
    • Dorn, G.W.1
  • 183
    • 67649695176 scopus 로고    scopus 로고
    • Involvement of toxic AGEs (TAGE) in the pathogenesis of diabetic vascular complications and Alzheimer's disease
    • Takeuchi, M. and Yamagishi, S. (2009) Involvement of toxic AGEs (TAGE) in the pathogenesis of diabetic vascular complications and Alzheimer's disease. J. Alzheimers Dis. 16, 845-858
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 845-858
    • Takeuchi, M.1    Yamagishi, S.2
  • 184
    • 84897568346 scopus 로고    scopus 로고
    • Role of methylglyoxal in Alzheimer's disease
    • Angeloni, C., Zambonin, L. and Hrelia, S. (2014) Role of methylglyoxal in Alzheimer's disease. BioMed. Res. Int. 2014, 238485
    • (2014) BioMed. Res. Int. , vol.2014 , pp. 238485
    • Angeloni, C.1    Zambonin, L.2    Hrelia, S.3
  • 187
    • 36849076840 scopus 로고    scopus 로고
    • Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia
    • Southern, L., Williams, J. and Esiri, M.M. (2007) Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia. BMC Neurol. 7, 35
    • (2007) BMC Neurol. , vol.7 , pp. 35
    • Southern, L.1    Williams, J.2    Esiri, M.M.3
  • 189
    • 79952785518 scopus 로고    scopus 로고
    • Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease
    • Rahmadi, A., Steiner, N. and Münch, G. (2011) Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease. Clin. Chem. Lab. Med. 49, 385-391
    • (2011) Clin. Chem. Lab. Med. , vol.49 , pp. 385-391
    • Rahmadi, A.1    Steiner, N.2    Münch, G.3
  • 191
    • 84861521520 scopus 로고    scopus 로고
    • Amyloid-ß metabolite sensing: biochemical linking of glycation modification and misfolding
    • Fawver, J.N., Schall, H.E., Petrofes Chapa, R.D., Zhu, X. and Murray, I.V.J. (2012) Amyloid-ß metabolite sensing: biochemical linking of glycation modification and misfolding. J. Alzheimers Dis. 30, 63-73
    • (2012) J. Alzheimers Dis. , vol.30 , pp. 63-73
    • Fawver, J.N.1    Schall, H.E.2    Petrofes Chapa, R.D.3    Zhu, X.4    Murray, I.V.J.5
  • 192
    • 0028959714 scopus 로고
    • Are advanced glycation end-products associated with amyloidosis in Alzheimer's disease
    • Kimura, T., Takamatsu, J., Araki, N., Goto, M., Kondo, A., Miyakawa, T. et al. (1995) Are advanced glycation end-products associated with amyloidosis in Alzheimer's disease. NeuroReport 6, 866-868
    • (1995) NeuroReport , vol.6 , pp. 866-868
    • Kimura, T.1    Takamatsu, J.2    Araki, N.3    Goto, M.4    Kondo, A.5    Miyakawa, T.6
  • 193
    • 0031050268 scopus 로고    scopus 로고
    • Risk of dementia among persons with diabetes mellitus: a population-based cohort study
    • Leibson, C.L., Rocca, W.A., Hanson, V.A., Cha, R., Kokmen, E., O'Brien, P.C. et al. (1997) Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am. J. Epidemiol. 145, 301-308
    • (1997) Am. J. Epidemiol. , vol.145 , pp. 301-308
    • Leibson, C.L.1    Rocca, W.A.2    Hanson, V.A.3    Cha, R.4    Kokmen, E.5    O'Brien, P.C.6
  • 194
    • 34548711907 scopus 로고    scopus 로고
    • Type 2 diabetes and risk of cognitive impairment and dementia
    • Whitmer, R.A. (2007) Type 2 diabetes and risk of cognitive impairment and dementia. Curr. Neurol. Neurosci. Rep. 7, 373-380
    • (2007) Curr. Neurol. Neurosci. Rep. , vol.7 , pp. 373-380
    • Whitmer, R.A.1
  • 195
    • 80555157642 scopus 로고    scopus 로고
    • Glucose tolerance status and risk of dementia in the community: the Hisayama study
    • Ohara, T., Doi, Y., Ninomiya, T., Hirakawa, Y., Hata, J., Iwaki, T. et al. (2011) Glucose tolerance status and risk of dementia in the community: the Hisayama study. Neurology 77, 1126-1134
    • (2011) Neurology , vol.77 , pp. 1126-1134
    • Ohara, T.1    Doi, Y.2    Ninomiya, T.3    Hirakawa, Y.4    Hata, J.5    Iwaki, T.6
  • 198
    • 33845704496 scopus 로고    scopus 로고
    • Diabetes is related to cerebral infarction but not to AD pathology in older persons
    • Arvanitakis, Z., Schneider, J.A., Wilson, R.S., Li, Y., Arnold, S.E., Wang, Z. et al. (2006) Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology 67, 1960-1965
    • (2006) Neurology , vol.67 , pp. 1960-1965
    • Arvanitakis, Z.1    Schneider, J.A.2    Wilson, R.S.3    Li, Y.4    Arnold, S.E.5    Wang, Z.6
  • 199
    • 77957940731 scopus 로고    scopus 로고
    • Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study
    • Ahtiluoto, S., Polvikoski, T., Peltonen, M., Solomon, A., Tuomilehto, J., Winblad, B. et al. (2010) Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study. Neurology 75, 1195-1202
    • (2010) Neurology , vol.75 , pp. 1195-1202
    • Ahtiluoto, S.1    Polvikoski, T.2    Peltonen, M.3    Solomon, A.4    Tuomilehto, J.5    Winblad, B.6
  • 201
    • 64049098761 scopus 로고    scopus 로고
    • Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship
    • Nelson, P.T., Braak, H. and Markesbery, W.R. (2009) Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship. J. Neuropathol. Exp. Neurol. 68, 1-14
    • (2009) J. Neuropathol. Exp. Neurol. , vol.68 , pp. 1-14
    • Nelson, P.T.1    Braak, H.2    Markesbery, W.R.3
  • 202
    • 84976512375 scopus 로고    scopus 로고
    • The role of insulin resistance and glucose metabolism dysregulation in the development of Alzheimer's Disease
    • Arrieta-Cruz, I. and Gutiérrez-Juárez, R. (2016) The role of insulin resistance and glucose metabolism dysregulation in the development of Alzheimer's Disease. Rev. Invest. Cĺin. 68, 53-58
    • (2016) Rev. Invest. Cĺin. , vol.68 , pp. 53-58
    • Arrieta-Cruz, I.1    Gutiérrez-Juárez, R.2
  • 203
    • 80052400687 scopus 로고    scopus 로고
    • Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association
    • Gorelick, P.B., Scuteri, A., Black, S.E., Decarli, C., Greenberg, S.M., Iadecola, C. et al. (2011) Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 42, 2672-2713
    • (2011) Stroke , vol.42 , pp. 2672-2713
    • Gorelick, P.B.1    Scuteri, A.2    Black, S.E.3    Decarli, C.4    Greenberg, S.M.5    Iadecola, C.6
  • 205
    • 84923270529 scopus 로고    scopus 로고
    • Elevated HbA1c is associated with increased risk of incident dementia in primary care patients
    • Ramirez, A., Wolfsgruber, S., Lange, C., Kaduszkiewicz, H., Weyerer, S., Werle, J. et al. (2015) Elevated HbA1c is associated with increased risk of incident dementia in primary care patients. J. Alzheimers Dis. 44, 1203-1212
    • (2015) J. Alzheimers Dis. , vol.44 , pp. 1203-1212
    • Ramirez, A.1    Wolfsgruber, S.2    Lange, C.3    Kaduszkiewicz, H.4    Weyerer, S.5    Werle, J.6
  • 206
    • 77951909056 scopus 로고    scopus 로고
    • Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.
    • Pan, X., Gong, N., Zhao, J., Yu, Z., Gu, F., Chen, J. et al. (2010) Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice. Brain J. Neurol. 133 (Pt 5), 1342-1351
    • (2010) Brain J. Neurol. , vol.133 , pp. 1342-1351
    • Pan, X.1    Gong, N.2    Zhao, J.3    Yu, Z.4    Gu, F.5    Chen, J.6
  • 207
    • 84861466154 scopus 로고    scopus 로고
    • Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease
    • Byun, K., Bayarsaikhan, E., Kim, D., Kim, C.Y., Mook-Jung, I., Paek, S.H. et al. (2012) Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease. PloS One 7, e37917
    • (2012) PloS One , vol.7
    • Byun, K.1    Bayarsaikhan, E.2    Kim, D.3    Kim, C.Y.4    Mook-Jung, I.5    Paek, S.H.6
  • 209
    • 84897555551 scopus 로고    scopus 로고
    • Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans
    • Cai, W., Uribarri, J., Zhu, L., Chen, X., Swamy, S., Zhao, Z. et al. (2014) Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans. Proc. Natl. Acad. Sci. U.S.A. 111, 4940-4945
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 4940-4945
    • Cai, W.1    Uribarri, J.2    Zhu, L.3    Chen, X.4    Swamy, S.5    Zhao, Z.6
  • 210
    • 84883733870 scopus 로고    scopus 로고
    • Molecular links between Alzheimer's disease and diabetes mellitus
    • Yang, Y. and Song, W. (2013) Molecular links between Alzheimer's disease and diabetes mellitus. Neuroscience 250, 140-150
    • (2013) Neuroscience , vol.250 , pp. 140-150
    • Yang, Y.1    Song, W.2
  • 211
    • 0028065142 scopus 로고
    • Analysis of microtubule-associated protein tau glycation in paired helical filaments
    • Ledesma, M.D., Bonay, P., Colaço, C. and Avila, J. (1994) Analysis of microtubule-associated protein tau glycation in paired helical filaments. J. Biol. Chem. 269, 21614-21619
    • (1994) J. Biol. Chem. , vol.269 , pp. 21614-21619
    • Ledesma, M.D.1    Bonay, P.2    Colaço, C.3    Avila, J.4
  • 212
    • 0035847269 scopus 로고    scopus 로고
    • Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
    • Sasaki, N., Toki, S., Chowei, H., Saito, T., Nakano, N., Hayashi, Y. et al. (2001) Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease. Brain Res. 888, 256-262
    • (2001) Brain Res. , vol.888 , pp. 256-262
    • Sasaki, N.1    Toki, S.2    Chowei, H.3    Saito, T.4    Nakano, N.5    Hayashi, Y.6
  • 213
    • 12144278195 scopus 로고    scopus 로고
    • Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains
    • Lüth, H.-J., Ogunlade, V., Kuhla, B., Kientsch-Engel, R., Stahl, P., Webster, J. et al. (2005) Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains. Cereb. Cortex 15, 211-220
    • (2005) Cereb. Cortex , vol.15 , pp. 211-220
    • Lüth, H.-J.1    Ogunlade, V.2    Kuhla, B.3    Kientsch-Engel, R.4    Stahl, P.5    Webster, J.6
  • 214
    • 84875827340 scopus 로고    scopus 로고
    • Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-ß by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro
    • Shimizu, F., Sano, Y., Tominaga, O., Maeda, T., Abe, M. and Kanda, T. (2013) Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-ß by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro. Neurobiol. Aging 34, 1902-1912
    • (2013) Neurobiol. Aging , vol.34 , pp. 1902-1912
    • Shimizu, F.1    Sano, Y.2    Tominaga, O.3    Maeda, T.4    Abe, M.5    Kanda, T.6
  • 215
    • 78650659385 scopus 로고    scopus 로고
    • Apical-to-basolateral transport of amyloid-ß peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein
    • Candela, P., Gosselet, F., Saint-Pol, J., Sevin, E., Boucau, M.-C., Boulanger, E. et al. (2010) Apical-to-basolateral transport of amyloid-ß peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein. J. Alzheimers Dis. 22, 849-859
    • (2010) J. Alzheimers Dis. , vol.22 , pp. 849-859
    • Candela, P.1    Gosselet, F.2    Saint-Pol, J.3    Sevin, E.4    Boucau, M.-C.5    Boulanger, E.6
  • 216
    • 77951647591 scopus 로고    scopus 로고
    • RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
    • Fang, F., Lue, L.-F., Yan, S., Xu, H., Luddy, J.S., Chen, D. et al. (2010) RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease. FASEB J. 24, 1043-1055
    • (2010) FASEB J. , vol.24 , pp. 1043-1055
    • Fang, F.1    Lue, L.-F.2    Yan, S.3    Xu, H.4    Luddy, J.S.5    Chen, D.6
  • 217
    • 79954585505 scopus 로고    scopus 로고
    • Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
    • Srikanth, V., Maczurek, A., Phan, T., Steele, M., Westcott, B., Juskiw, D. et al. (2011) Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease. Neurobiol. Aging 32, 763-777
    • (2011) Neurobiol. Aging , vol.32 , pp. 763-777
    • Srikanth, V.1    Maczurek, A.2    Phan, T.3    Steele, M.4    Westcott, B.5    Juskiw, D.6
  • 218
    • 84856802897 scopus 로고    scopus 로고
    • Hypoxia induces angiogenic factors in brain microvascular endothelial cells
    • Luo, J., Martinez, J., Yin, X., Sanchez, A., Tripathy, D. and Grammas, P. (2012) Hypoxia induces angiogenic factors in brain microvascular endothelial cells. Microvasc. Res. 83, 138-145
    • (2012) Microvasc. Res. , vol.83 , pp. 138-145
    • Luo, J.1    Martinez, J.2    Yin, X.3    Sanchez, A.4    Tripathy, D.5    Grammas, P.6
  • 219
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass, C.K., Saijo, K., Winner, B., Marchetto, M.C. and Gage, F.H. (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 220
    • 84855533945 scopus 로고    scopus 로고
    • Involvement of rat hippocampal astrocytes in ß-amyloid-induced angiogenesis and neuroinflammation
    • Fioravanzo, L., Venturini, M., Di Liddo, R., Liddo, R.D., Marchi, F., Grandi, C. et al. (2010) Involvement of rat hippocampal astrocytes in ß-amyloid-induced angiogenesis and neuroinflammation. Curr. Alzheimer Res. 7, 591-601
    • (2010) Curr. Alzheimer Res. , vol.7 , pp. 591-601
    • Fioravanzo, L.1    Venturini, M.2    Di Liddo, R.3    Liddo, R.D.4    Marchi, F.5    Grandi, C.6
  • 221
    • 1242338809 scopus 로고    scopus 로고
    • Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease
    • Yang, S.-P., Bae, D.-G., Kang, H.J., Gwag, B.J., Gho, Y.S. and Chae, C.-B. (2004) Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease. Neurobiol. Aging 25, 283-290
    • (2004) Neurobiol. Aging , vol.25 , pp. 283-290
    • Yang, S.-P.1    Bae, D.-G.2    Kang, H.J.3    Gwag, B.J.4    Gho, Y.S.5    Chae, C.-B.6
  • 222
    • 84859723641 scopus 로고    scopus 로고
    • A multimodal RAGE-specific inhibitor reduces amyloid ß-mediated brain disorder in a mouse model of Alzheimer disease
    • Deane, R., Singh, I., Sagare, A.P., Bell, R.D., Ross, N.T., LaRue, B. et al. (2012) A multimodal RAGE-specific inhibitor reduces amyloid ß-mediated brain disorder in a mouse model of Alzheimer disease. J. Clin. Invest. 122, 1377-1392
    • (2012) J. Clin. Invest. , vol.122 , pp. 1377-1392
    • Deane, R.1    Singh, I.2    Sagare, A.P.3    Bell, R.D.4    Ross, N.T.5    LaRue, B.6
  • 223
    • 28044449557 scopus 로고    scopus 로고
    • Advanced glycation end products and diabetic nephropathy
    • Thomas, M.C., Forbes, J.M. and Cooper, M.E. (2005) Advanced glycation end products and diabetic nephropathy. Am. J. Ther. 12, 562-572
    • (2005) Am. J. Ther. , vol.12 , pp. 562-572
    • Thomas, M.C.1    Forbes, J.M.2    Cooper, M.E.3
  • 224
    • 77951622247 scopus 로고    scopus 로고
    • Potential new therapeutic agents for diabetic kidney disease
    • Turgut, F. and Bolton, W.K. (2010) Potential new therapeutic agents for diabetic kidney disease. Am. J. Kidney Dis. 55, 928-940
    • (2010) Am. J. Kidney Dis. , vol.55 , pp. 928-940
    • Turgut, F.1    Bolton, W.K.2
  • 225
    • 0036236805 scopus 로고    scopus 로고
    • Pimagedine: a novel therapy for diabetic nephropathy
    • Abdel-Rahman, E. and Bolton, W.K. (2002) Pimagedine: a novel therapy for diabetic nephropathy. Expert Opin. Invest. Drugs 11, 565-574
    • (2002) Expert Opin. Invest. Drugs , vol.11 , pp. 565-574
    • Abdel-Rahman, E.1    Bolton, W.K.2
  • 226
    • 0032857820 scopus 로고    scopus 로고
    • Control Clin
    • Freedman, B.I., Wuerth, J.P., Cartwright, K., Bain, R.P., Dippe, S., Hershon, K. et al. (1999) Design and baseline characteristics for the Aminoguanidine Clinical Trial in Overt Type 2 Diabetic Nephropathy (ACTION II). Control Clin. Trials 20, 493-510
    • (1999) Trials , vol.20 , pp. 493-510
    • Freedman, B.I.1    Wuerth, J.P.2    Cartwright, K.3    Bain, R.P.4    Dippe, S.5    Hershon, K.6
  • 227
    • 34250830236 scopus 로고    scopus 로고
    • Antibodies against RAGE in sepsis and inflammation: implications for therapy
    • Lutterloh, E.C. and Opal, S.M. (2007) Antibodies against RAGE in sepsis and inflammation: implications for therapy. Expert Opin. Pharmacother. 8, 1193-1196
    • (2007) Expert Opin. Pharmacother. , vol.8 , pp. 1193-1196
    • Lutterloh, E.C.1    Opal, S.M.2
  • 228
    • 84953287235 scopus 로고    scopus 로고
    • Effects of RAGE-specific inhibitor FPS-ZM1 on amyloid-ß metabolism and AGEs-induced inflammation and oxidative stress in rat hippocampus
    • Hong, Y., Shen, C., Yin, Q., Sun, M., Ma, Y. and Liu, X. (2016) Effects of RAGE-specific inhibitor FPS-ZM1 on amyloid-ß metabolism and AGEs-induced inflammation and oxidative stress in rat hippocampus. Neurochem. Res. 41, 1192-1199
    • (2016) Neurochem. Res. , vol.41 , pp. 1192-1199
    • Hong, Y.1    Shen, C.2    Yin, Q.3    Sun, M.4    Ma, Y.5    Liu, X.6
  • 229
    • 84906963073 scopus 로고    scopus 로고
    • Contribution of receptor for advanced glycation end products to vasculature-protecting effects of exercise training in aged rats
    • Gu, Q., Wang, B., Zhang, X.-F., Ma, Y.-P., Liu, J.-D. and Wang, X.-Z. (2014) Contribution of receptor for advanced glycation end products to vasculature-protecting effects of exercise training in aged rats. Eur. J. Pharmacol. 741, 186-194
    • (2014) Eur. J. Pharmacol. , vol.741 , pp. 186-194
    • Gu, Q.1    Wang, B.2    Zhang, X.-F.3    Ma, Y.-P.4    Liu, J.-D.5    Wang, X.-Z.6
  • 230
    • 80052258842 scopus 로고    scopus 로고
    • PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease
    • Sabbagh, M.N., Agro, A., Bell, J., Aisen, P.S., Schweizer, E. and Galasko, D. (2011) PF-04494700, an oral inhibitor of receptor for advanced glycation end products (RAGE), in Alzheimer disease. Alzheimer Dis. Assoc. Disord. 25, 206-212
    • (2011) Alzheimer Dis. Assoc. Disord. , vol.25 , pp. 206-212
    • Sabbagh, M.N.1    Agro, A.2    Bell, J.3    Aisen, P.S.4    Schweizer, E.5    Galasko, D.6
  • 231
    • 84902173668 scopus 로고    scopus 로고
    • Clinical trial of an inhibitor of RAGE-Aß interactions in Alzheimer disease
    • Galasko, D., Bell, J., Mancuso, J.Y., Kupiec, J.W., Sabbagh, M.N., van Dyck, C. et al. (2014) Clinical trial of an inhibitor of RAGE-Aß interactions in Alzheimer disease. Neurology 82, 1536-1542
    • (2014) Neurology , vol.82 , pp. 1536-1542
    • Galasko, D.1    Bell, J.2    Mancuso, J.Y.3    Kupiec, J.W.4    Sabbagh, M.N.5    van Dyck, C.6
  • 233
    • 77954057601 scopus 로고    scopus 로고
    • Deletion of RAGE causes hyperactivity and increased sensitivity to auditory stimuli in mice
    • Sakatani, S., Yamada, K., Homma, C., Munesue, S., Yamamoto, Y., Yamamoto, H. et al. (2009) Deletion of RAGE causes hyperactivity and increased sensitivity to auditory stimuli in mice. PloS One 4, e8309
    • (2009) PloS One , vol.4
    • Sakatani, S.1    Yamada, K.2    Homma, C.3    Munesue, S.4    Yamamoto, Y.5    Yamamoto, H.6
  • 235
    • 0034695098 scopus 로고    scopus 로고
    • The biology of the receptor for advanced glycation end products and its ligands
    • Schmidt, A.M., Yan, S.D., Yan, S.F. and Stern, D.M. (2000) The biology of the receptor for advanced glycation end products and its ligands. Biochim. Biophys. Acta 1498, 99-111
    • (2000) Biochim. Biophys. Acta , vol.1498 , pp. 99-111
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 236
    • 0035464966 scopus 로고    scopus 로고
    • Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo
    • Szwergold, B.S., Howell, S. and Beisswenger, P.J. (2001) Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo. Diabetes 50, 2139-2147
    • (2001) Diabetes , vol.50 , pp. 2139-2147
    • Szwergold, B.S.1    Howell, S.2    Beisswenger, P.J.3
  • 237
    • 0036683724 scopus 로고    scopus 로고
    • Fructosamine 3-kinase is involved in an intracellular deglycation pathway in human erythrocytes.
    • Delpierre, G., Collard, F., Fortpied, J. and Van Schaftingen, E. (2002) Fructosamine 3-kinase is involved in an intracellular deglycation pathway in human erythrocytes. Biochem. J. 365 (Pt 3), 801-808
    • (2002) Biochem. J. , vol.365 , pp. 801-808
    • Delpierre, G.1    Collard, F.2    Fortpied, J.3    Van Schaftingen, E.4
  • 239
    • 78650044928 scopus 로고    scopus 로고
    • Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function
    • Miller, A.G., Tan, G., Binger, K.J., Pickering, R.J., Thomas, M.C., Nagaraj, R.H. et al. (2010) Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function. Diabetes 59, 3208-3215
    • (2010) Diabetes , vol.59 , pp. 3208-3215
    • Miller, A.G.1    Tan, G.2    Binger, K.J.3    Pickering, R.J.4    Thomas, M.C.5    Nagaraj, R.H.6
  • 240
    • 0036612722 scopus 로고    scopus 로고
    • Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal
    • Nagaraj, R.H., Sarkar, P., Mally, A., Biemel, K.M., Lederer, M.O. and Padayatti, P.S. (2002) Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal. Arch. Biochem. Biophys. 402, 110-119
    • (2002) Arch. Biochem. Biophys. , vol.402 , pp. 110-119
    • Nagaraj, R.H.1    Sarkar, P.2    Mally, A.3    Biemel, K.M.4    Lederer, M.O.5    Padayatti, P.S.6
  • 241
    • 84866369891 scopus 로고    scopus 로고
    • Resveratrol upregulates nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells
    • Cheng, A.-S., Cheng, Y.-H., Chiou, C.-H. and Chang, T.-L. (2012) Resveratrol upregulates nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells. J. Agric. Food Chem. 60, 9180-9187
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 9180-9187
    • Cheng, A.-S.1    Cheng, Y.-H.2    Chiou, C.-H.3    Chang, T.-L.4
  • 242
    • 84980371738 scopus 로고    scopus 로고
    • Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation
    • Xue, M., Weickert, M.O., Qureshi, S., Kandala, N-B, Anwar, A., Waldron, M. et al. (2016) Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation. Diabetes 65, 2282-2294
    • (2016) Diabetes , vol.65 , pp. 2282-2294
    • Xue, M.1    Weickert, M.O.2    Qureshi, S.3    Kandala N-B Anwar, A.4    Waldron, M.5
  • 243
    • 84939569848 scopus 로고    scopus 로고
    • Soluble RAGEs-prospects for treating & tracking metabolic and inflammatory disease
    • Schmidt, A.M. (2015) Soluble RAGEs-prospects for treating & tracking metabolic and inflammatory disease. Vasc. Pharmacol. 72, 1-8
    • (2015) Vasc. Pharmacol. , vol.72 , pp. 1-8
    • Schmidt, A.M.1
  • 244
    • 43249092154 scopus 로고    scopus 로고
    • Identification, classification, and expression of RAGE gene splice variants
    • Hudson, B.I., Carter, A.M., Harja, E., Kalea, A.Z., Arriero, M., Yang, H. et al. (2008) Identification, classification, and expression of RAGE gene splice variants. FASEB J. 22, 1572-1580
    • (2008) FASEB J. , vol.22 , pp. 1572-1580
    • Hudson, B.I.1    Carter, A.M.2    Harja, E.3    Kalea, A.Z.4    Arriero, M.5    Yang, H.6
  • 245
    • 54049108485 scopus 로고    scopus 로고
    • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
    • Raucci, A., Cugusi, S., Antonelli, A., Barabino, S.M., Monti, L., Bierhaus, A. et al. (2008) A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J. 22, 3716-3727
    • (2008) FASEB J. , vol.22 , pp. 3716-3727
    • Raucci, A.1    Cugusi, S.2    Antonelli, A.3    Barabino, S.M.4    Monti, L.5    Bierhaus, A.6
  • 246
    • 0034880114 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice
    • Goova, M.T., Li, J., Kislinger, T., Qu, W., Lu, Y., Bucciarelli, L.G. et al. (2001) Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice. Am. J. Pathol. 159, 513-525
    • (2001) Am. J. Pathol. , vol.159 , pp. 513-525
    • Goova, M.T.1    Li, J.2    Kislinger, T.3    Qu, W.4    Lu, Y.5    Bucciarelli, L.G.6
  • 247
    • 0034102284 scopus 로고    scopus 로고
    • Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice
    • Lalla, E., Lamster, I.B., Feit, M., Huang, L., Spessot, A., Qu, W. et al. (2000) Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice. J. Clin. Invest. 105, 1117-1124
    • (2000) J. Clin. Invest. , vol.105 , pp. 1117-1124
    • Lalla, E.1    Lamster, I.B.2    Feit, M.3    Huang, L.4    Spessot, A.5    Qu, W.6
  • 248
    • 84988646859 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end products protects against systolic overload-induced heart failure after transverse aortic constriction in mice
    • Liu, Y., Yu, M., Zhang, Z., Yu, Y., Chen, Q., Zhang, W. et al. (2016) Blockade of receptor for advanced glycation end products protects against systolic overload-induced heart failure after transverse aortic constriction in mice. Eur. J. Pharmacol. 791, 535-543
    • (2016) Eur. J. Pharmacol. , vol.791 , pp. 535-543
    • Liu, Y.1    Yu, M.2    Zhang, Z.3    Yu, Y.4    Chen, Q.5    Zhang, W.6
  • 249
    • 10744229479 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice
    • Zeng, S., Feirt, N., Goldstein, M., Guarrera, J., Ippagunta, N., Ekong, U. et al. (2004) Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice. Hepatology 39, 422-432
    • (2004) Hepatology , vol.39 , pp. 422-432
    • Zeng, S.1    Feirt, N.2    Goldstein, M.3    Guarrera, J.4    Ippagunta, N.5    Ekong, U.6
  • 250
    • 77949527584 scopus 로고    scopus 로고
    • Soluble RAGE-modulating drugs: state-of-the-art and future perspectives for targeting vascular inflammation
    • Lanati, N., Emanuele, E., Brondino, N. and Geroldi, D. (2010) Soluble RAGE-modulating drugs: state-of-the-art and future perspectives for targeting vascular inflammation. Curr. Vasc. Pharmacol. 8, 86-92
    • (2010) Curr. Vasc. Pharmacol. , vol.8 , pp. 86-92
    • Lanati, N.1    Emanuele, E.2    Brondino, N.3    Geroldi, D.4


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