An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 6, 2000, Pages 2809-2813

  Asif, Mohammad ^a   Egan, John ^b   Vasan, Sara ^b   Jyothirmayi, Garikiparthy N ^a   Masurekar, Malthi R ^a   Lopez, Santos ^a   Williams, Chandra ^a   Torres, Ramon L ^a   Wagle, Dilip ^b   Ulrich, Peter ^c   Cerami, Anthony ^c   Brines, Michael ^c   Regan, Timothy J ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b Alteon Inc   (United States)

^c Kenneth S Warren Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALAGEBRIUM; PHENYL 4,5 DIMETHYLTHIAZOLIUM CHLORIDE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DRUG EFFECT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE MASS; HEART MUSCLE COMPLIANCE; HEART STROKE VOLUME; MALE; NONHUMAN; PRIORITY JOURNAL;

AGING; ANIMALS; DIASTOLE; DOGS; ELASTICITY; GLYCOSYLATION END PRODUCTS, ADVANCED; HEART RATE; HEART VENTRICLES; HEMODYNAMIC PROCESSES; MALE; MYOCARDIUM; STROKE VOLUME; SYSTOLE; THIAZOLES;

ANIMALIA; CANIS FAMILIARIS; MAMMALIA;

EID: 0034646372     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040558497     Document Type: Article

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