메뉴 건너뛰기




Volumn 98, Issue 2, 2015, Pages 135-144

Emerging targets for therapeutic development in diabetes and its complications: The RAGE signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANTIDIABETIC AGENT; BIOLOGICAL MARKER; DIAPH1 PROTEIN, HUMAN; GLUCOSE BLOOD LEVEL; IMMUNOGLOBULIN RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84962207552     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1002/cpt.148     Document Type: Article
Times cited : (82)

References (78)
  • 1
    • 4444228888 scopus 로고    scopus 로고
    • WHO Accessed 9 February 2015.
    • WHO. Obesity and Overweight. http://www.who.int/mediacentre/factsheets/fs311/en/ (2015). Accessed 9 February 2015
    • (2015) Obesity and Overweight
  • 2
    • 84907849523 scopus 로고    scopus 로고
    • CDC Accessed 9 February 2015.
    • CDC. Adult Obesity Facts. http://www.cdc.gov/obesity/data/adult.html (2014). Accessed 9 February 2015
    • (2014) Adult Obesity Facts
  • 3
    • 84906978168 scopus 로고    scopus 로고
    • CDC
    • CDC. National Diabetes Statistics Report. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf (2014
    • (2014) National Diabetes Statistics Report
  • 4
    • 0031851293 scopus 로고    scopus 로고
    • Definition diagnosis and classification of diabetes mellitus and its complications Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti, K.G., & Zimmet, P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Med. 15, 539-553 (1998
    • (1998) Diabetic Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 5
    • 84872864013 scopus 로고    scopus 로고
    • Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity
    • Gaens, K.H., Stehouwer, C.D., & Schalkwijk, C.G. Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity. Curr. Opin. Lipidol. 24, 4-11 (2013
    • (2013) Curr. Opin. Lipidol , vol.24 , pp. 4-11
    • Gaens, K.H.1    Stehouwer, C.D.2    Schalkwijk, C.G.3
  • 6
    • 0028068046 scopus 로고
    • Cellular receptors for advanced glycation end products Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
    • Schmidt, A.M., Hori, O., Brett, J., Yan, S.D., Wautier, J.L., & Stern, D. Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions. Arterioscler. Thromb. 14, 1521-1528 (1994
    • (1994) Arterioscler. Thromb , vol.14 , pp. 1521-1528
    • Schmidt, A.M.1    Hori, O.2    Brett, J.3    Yan, S.D.4    Wautier, J.L.5    Stern, D.6
  • 7
    • 79957811092 scopus 로고    scopus 로고
    • Inhibition of advanced glycation endproduct formation by foodstuffs
    • Wu, C.H., Huang, S.M., Lin, J.A., & Yen, G.C. Inhibition of advanced glycation endproduct formation by foodstuffs. Food Funct. 2, 224-234 (2011
    • (2011) Food Funct , vol.2 , pp. 224-234
    • Wu, C.H.1    Huang, S.M.2    Lin, J.A.3    Yen, G.C.4
  • 8
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • Goldin, A., Beckman, J.A., Schmidt, A.M., & Creager, M.A. Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 114, 597-605 (2006
    • (2006) Circulation , vol.114 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 9
    • 0034795140 scopus 로고    scopus 로고
    • The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
    • Schmidt, A.M., Yan, S.D., Yan, S.F., & Stern, D.M. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J. Clin. Invest. 108, 949-955 (2001
    • (2001) J. Clin. Invest , vol.108 , pp. 949-955
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 10
    • 63849315875 scopus 로고    scopus 로고
    • The role of impaired mitochondrial lipid oxidation in obesity
    • Rogge, M.M. The role of impaired mitochondrial lipid oxidation in obesity. Biol. Res. Nurs. 10, 356-373 (2009
    • (2009) Biol. Res. Nurs , vol.10 , pp. 356-373
    • Rogge, M.M.1
  • 11
    • 84901334017 scopus 로고    scopus 로고
    • RAGE regulates themetabolic and inflammatory response to high-fat feeding inmice
    • Song, F., et al. RAGE regulates themetabolic and inflammatory response to high-fat feeding inmice. Diabetes 63, 1948-1965 (2014
    • (2014) Diabetes , vol.63 , pp. 1948-1965
    • Song, F.1
  • 12
    • 0026650438 scopus 로고
    • Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
    • Schmidt, A.M., et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J. Biol. Chem. 267, 14987-14997 (1992
    • (1992) J. Biol. Chem , vol.267 , pp. 14987-14997
    • Schmidt, A.M.1
  • 13
    • 0027718105 scopus 로고
    • Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
    • Brett, J., et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am. J. Pathol. 143, 1699-1712 (1993
    • (1993) Am. J. Pathol , vol.143 , pp. 1699-1712
    • Brett, J.1
  • 14
    • 32444445050 scopus 로고    scopus 로고
    • Promotion of cell adherence and spreading: A novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type i cells
    • Demling, N., Ehrhardt, C., Kasper, M., Laue, M., Knels, L., & Rieber, E.P. Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res. 323, 475-488 (2006
    • (2006) Cell Tissue Res , vol.323 , pp. 475-488
    • Demling, N.1    Ehrhardt, C.2    Kasper, M.3    Laue, M.4    Knels, L.5    Rieber, E.P.6
  • 15
    • 0034682315 scopus 로고    scopus 로고
    • Blockade of RAGE-Amphoterin signalling suppresses tumour growth and metastases
    • Taguchi, A., et al. Blockade of RAGE-Amphoterin signalling suppresses tumour growth and metastases. Nature 405, 354-360 (2000
    • (2000) Nature , vol.405 , pp. 354-360
    • Taguchi, A.1
  • 16
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • Hofmann, M.A., et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97, 889-901 (1999
    • (1999) Cell , vol.97 , pp. 889-901
    • Hofmann, M.A.1
  • 17
    • 0013615899 scopus 로고    scopus 로고
    • RAGE and amyloid-beta peptide neurotoxicity in Alzheimers disease
    • Yan, S.D., et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimers disease. Nature 382, 685-691 (1996
    • (1996) Nature , vol.382 , pp. 685-691
    • Yan, S.D.1
  • 18
    • 84871909158 scopus 로고    scopus 로고
    • Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling
    • Rai, V., et al. Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. J. Exp. Med. 209, 2339-2350 (2012
    • (2012) J. Exp. Med , vol.209 , pp. 2339-2350
    • Rai, V.1
  • 19
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment
    • Chavakis, T., et al. The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment. J. Exp. Med. 198, 1507-1515 (2003
    • (2003) J. Exp. Med , vol.198 , pp. 1507-1515
    • Chavakis, T.1
  • 20
    • 57749122052 scopus 로고    scopus 로고
    • Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42
    • Hudson, B.I., et al. Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J. Biol. Chem. 283, 34457-34468 (2008
    • (2008) J. Biol. Chem , vol.283 , pp. 34457-34468
    • Hudson, B.I.1
  • 21
    • 0041758426 scopus 로고    scopus 로고
    • The formins: Active scaffolds that remodel the cytoskeleton
    • Wallar, B.J., & Alberts, A.S. The formins: active scaffolds that remodel the cytoskeleton. Trends Cell Biol. 13, 435-46 (2003
    • (2003) Trends Cell Biol , vol.13 , pp. 435-446
    • Wallar, B.J.1    Alberts, A.S.2
  • 22
    • 84903978020 scopus 로고    scopus 로고
    • Formins as effector proteins of Rho GTPases
    • Kuhn, S., & Geyer, M. Formins as effector proteins of Rho GTPases. Small GTPases 5, e29513 (2014
    • (2014) Small GTPases , vol.5 , pp. e29513
    • Kuhn, S.1    Geyer, M.2
  • 23
    • 84888437392 scopus 로고    scopus 로고
    • Physiological roles of Rho and Rho effectors inmammals
    • Thumkeo, D.,Watanabe, S., & Narumiya, S. Physiological roles of Rho and Rho effectors inmammals. Eur. J. Cell Biol. 92, 303-315 (2013
    • (2013) Eur. J. Cell Biol , vol.92 , pp. 303-315
    • Thumkeo, D.1    Watanabe, S.2    Narumiya, S.3
  • 24
    • 84892503373 scopus 로고    scopus 로고
    • Complex tissuespecific patterns and distribution of multiple RAGE splice variants in different mammals
    • Lopez-Diez, R., Rastrojo, A., Villate, O., & Aguado, B. Complex tissuespecific patterns and distribution of multiple RAGE splice variants in different mammals. Genome Biol. Evol. 5, 2420-2435 (2013
    • (2013) Genome Biol. Evol , vol.5 , pp. 2420-2435
    • Lopez-Diez, R.1    Rastrojo, A.2    Villate, O.3    Aguado, B.4
  • 25
    • 78650853295 scopus 로고    scopus 로고
    • Enhanced expression of receptor for advanced glycation endproducts is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes
    • Tam, X.H., Shiu, S.W., Leng, L., Bucala, R., Betteridge, D.J., & Tan, K.C. Enhanced expression of receptor for advanced glycation endproducts is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes. Clin. Sci. (Lond) 120, 81-89 (2011
    • (2011) Clin. Sci. (Lond , vol.120 , pp. 81-89
    • Tam, X.H.1    Shiu, S.W.2    Leng, L.3    Bucala, R.4    Betteridge, D.J.5    Tan, K.C.6
  • 26
    • 33644808985 scopus 로고    scopus 로고
    • Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis
    • Koyama, H., et al. Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 25, 2587-2593 (2005
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 2587-2593
    • Koyama, H.1
  • 27
    • 33745741894 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products: From disease marker to potential therapeutic target
    • Geroldi, D., Falcone, C., & Emanuele, E. Soluble receptor for advanced glycation end products: from disease marker to potential therapeutic target. Curr. Med. Chem. 13, 1971-1978 (2006
    • (2006) Curr. Med. Chem , vol.13 , pp. 1971-1978
    • Geroldi, D.1    Falcone, C.2    Emanuele, E.3
  • 28
    • 84886441236 scopus 로고    scopus 로고
    • Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease
    • Cheng, D.T., et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. Am. J. Resp. Crit. Care Med. 188, 948-957 (2013
    • (2013) Am. J. Resp. Crit. Care Med , vol.188 , pp. 948-957
    • Cheng, D.T.1
  • 29
    • 73249144472 scopus 로고    scopus 로고
    • Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels
    • Gaens, K.H., et al. Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels. J. Clin. Endocrinol. Metab. 94, 5174-5180 (2009
    • (2009) J. Clin. Endocrinol. Metab , vol.94 , pp. 5174-5180
    • Gaens, K.H.1
  • 30
    • 14744274872 scopus 로고    scopus 로고
    • Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients
    • Prevost, G., et al. Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients. Diabetes Metab. 31, 35-39 (2005
    • (2005) Diabetes Metab , vol.31 , pp. 35-39
    • Prevost, G.1
  • 31
    • 33847649968 scopus 로고    scopus 로고
    • Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India
    • Ramprasad, S., Radha, V., Mathias, R.A., Majumder, P.P., Rao, M.R., & Rema, M. Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India. Eye (Lond 21, 395-401 (2007
    • (2007) Eye (Lond , vol.21 , pp. 395-401
    • Ramprasad, S.1    Radha, V.2    Mathias, R.A.3    Majumder, P.P.4    Rao, M.R.5    Rema, M.6
  • 32
    • 78149267892 scopus 로고    scopus 로고
    • Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy
    • Balasubbu, S., et al. Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy. BMC Med. Genet. 11, 158 (2010
    • (2010) BMC Med. Genet , vol.11 , pp. 158
    • Balasubbu, S.1
  • 33
    • 84908070235 scopus 로고    scopus 로고
    • Up-regulation of the receptor for advanced glycation end products in the skin biopsy specimens of patients with severe diabetic neuropathy
    • Park, S.Y., Kim, Y.A., Hong, Y.H., Moon, M.K., Koo, B.K., & Kim, T.W. Up-regulation of the receptor for advanced glycation end products in the skin biopsy specimens of patients with severe diabetic neuropathy. J. Clin. Neurol. 10, 334-341 (2014
    • (2014) J. Clin. Neurol , vol.10 , pp. 334-341
    • Park, S.Y.1    Kim, Y.A.2    Hong, Y.H.3    Moon, M.K.4    Koo, B.K.5    Kim, T.W.6
  • 34
    • 85047694774 scopus 로고    scopus 로고
    • Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily
    • Bierhaus, A., et al. Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. J. Clin. Invest. 114, 1741-1751 (2004
    • (2004) J. Clin. Invest , vol.114 , pp. 1741-1751
    • Bierhaus, A.1
  • 35
    • 84874439683 scopus 로고    scopus 로고
    • RAGE deficiency improves postinjury sciatic nerve regeneration in type 1 diabetic mice
    • Juranek, J.K., et al. RAGE deficiency improves postinjury sciatic nerve regeneration in type 1 diabetic mice. Diabetes 62, 931-943 (2013
    • (2013) Diabetes , vol.62 , pp. 931-943
    • Juranek, J.K.1
  • 36
    • 84939943103 scopus 로고    scopus 로고
    • Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice
    • McVicar, C.M., et al. Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice. Diabetologia 58, 1129-1137 (2015
    • (2015) Diabetologia , vol.58 , pp. 1129-1137
    • McVicar, C.M.1
  • 37
    • 77955375901 scopus 로고    scopus 로고
    • Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse
    • Reiniger, N., et al. Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes 59, 2043-2054 (2010
    • (2010) Diabetes , vol.59 , pp. 2043-2054
    • Reiniger, N.1
  • 38
    • 77953440109 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy, causes and effects
    • Boudina, S., & Abel, E.D. Diabetic cardiomyopathy, causes and effects. Rev. Endocr. Metab. Disord. 11, 31-39 (2010
    • (2010) Rev. Endocr. Metab. Disord , vol.11 , pp. 31-39
    • Boudina, S.1    Abel, E.D.2
  • 39
    • 84882628768 scopus 로고    scopus 로고
    • Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes
    • Hutchinson, K.R., Lord, C.K., West, T.A., & Stewart, J.A., Jr. Cardiac fibroblast-dependent extracellular matrix accumulation is associated with diastolic stiffness in type 2 diabetes. PloS One 8, e72080 (2013
    • (2013) PloS One , vol.8 , pp. e72080
    • Hutchinson, K.R.1    Lord, C.K.2    West, T.A.3    Stewart, J.A.4
  • 40
    • 84906040999 scopus 로고    scopus 로고
    • Effects of advanced glycation end products on calcium handling in cardiomyocytes
    • Yan, D., et al. Effects of advanced glycation end products on calcium handling in cardiomyocytes. Cardiology 129, 75-83 (2014
    • (2014) Cardiology , vol.129 , pp. 75-83
    • Yan, D.1
  • 41
    • 52749084063 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes
    • Soro-Paavonen, A., et al. Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 57, 2461-2469 (2008
    • (2008) Diabetes , vol.57 , pp. 2461-2469
    • Soro-Paavonen, A.1
  • 42
    • 77950987553 scopus 로고    scopus 로고
    • Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice
    • Bu, D.X., et al. Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice. Circ. Res. 106, 1040-1051 2010
    • (2010) Circ. Res , vol.106 , pp. 1040-1051
    • Bu, D.X.1
  • 43
    • 84962311193 scopus 로고    scopus 로고
    • The relationship between inflammation and impaired wound healing in a diabetic rat burn model
    • e-pub ahead of print
    • Tian, M., et al. The relationship between inflammation and impaired wound healing in a diabetic rat burn model. J. Burn Care Res. e-pub ahead of print 2014
    • (2014) J. Burn Care Res
    • Tian, M.1
  • 44
    • 84893199488 scopus 로고    scopus 로고
    • High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products
    • Nadatani, Y., et al. High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products. PloS One 8, e80130 (2013
    • (2013) PloS One , vol.8 , pp. e80130
    • Nadatani, Y.1
  • 45
    • 84869087805 scopus 로고    scopus 로고
    • The soluble form of the receptor of advanced glycation endproducts increases after bariatric surgery in morbid obesity
    • Brix, J.M., Hollerl, F., Kopp, H.P., Schernthaner, G.H., & Schernthaner, G. The soluble form of the receptor of advanced glycation endproducts increases after bariatric surgery in morbid obesity. Int. J. Obes. (Lond) 36, 1412-1417 (2012
    • (2012) Int. J. Obes. (Lond , vol.36 , pp. 1412-1417
    • Brix, J.M.1    Hollerl, F.2    Kopp, H.P.3    Schernthaner, G.H.4    Schernthaner, G.5
  • 46
    • 60349094487 scopus 로고    scopus 로고
    • Circulating soluble receptor for advanced glycation end products is inversely associated with body mass index and waist/hip ratio in the general population
    • Norata, G.D., et al. Circulating soluble receptor for advanced glycation end products is inversely associated with body mass index and waist/hip ratio in the general population. Nutr. Metab. Cardiovasc. Dis. NMCD 19, 129-134 (2009
    • (2009) Nutr. Metab. Cardiovasc. Dis. NMCD , vol.19 , pp. 129-134
    • Norata, G.D.1
  • 47
    • 34547659641 scopus 로고    scopus 로고
    • Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes
    • Tan, K.C., et al. Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes. Diabetologia 50, 1819-1825 (2007
    • (2007) Diabetologia , vol.50 , pp. 1819-1825
    • Tan, K.C.1
  • 48
    • 79955537037 scopus 로고    scopus 로고
    • Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: The Northern Manhattan Study (NOMAS
    • Hudson, B.I., et al. Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: the Northern Manhattan Study (NOMAS). Atherosclerosis 216, 192-198 (2011
    • (2011) Atherosclerosis , vol.216 , pp. 192-198
    • Hudson, B.I.1
  • 49
    • 18244381813 scopus 로고    scopus 로고
    • Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men
    • Falcone, C., et al. Plasma levels of soluble receptor for advanced glycation end products and coronary artery disease in nondiabetic men. Arterioscler. Thromb. Vasc. Biol. 25, 1032-1037 (2005
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 1032-1037
    • Falcone, C.1
  • 50
    • 34548740746 scopus 로고    scopus 로고
    • Decreased plasma soluble RAGE in patients with hypercholesterolemia: Effects of statins
    • Santilli, F., et al. Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins. Free Radic. Biol. Med. 43, 1255-1262 (2007
    • (2007) Free Radic. Biol. Med , vol.43 , pp. 1255-1262
    • Santilli, F.1
  • 51
    • 27744510124 scopus 로고    scopus 로고
    • Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia
    • Emanuele, E., et al. Circulating levels of soluble receptor for advanced glycation end products in Alzheimer disease and vascular dementia. Arch. Neurol. 62, 1734-1736 (2005
    • (2005) Arch. Neurol , vol.62 , pp. 1734-1736
    • Emanuele, E.1
  • 52
    • 79953141815 scopus 로고    scopus 로고
    • Increased serum high-mobility group box-1 and cleaved receptor for advanced glycation endproducts levels and decreased endogenous secretory receptor for advanced glycation endproducts levels in diabetic and non-diabetic patients with heart failure
    • Wang, L.J., Lu, L., Zhang, F.R., Chen, Q.J., De Caterina, R., & Shen, W.F. Increased serum high-mobility group box-1 and cleaved receptor for advanced glycation endproducts levels and decreased endogenous secretory receptor for advanced glycation endproducts levels in diabetic and non-diabetic patients with heart failure. Eur. J. Heart Fail. 13, 440-449 (2011
    • (2011) Eur. J. Heart Fail , vol.13 , pp. 440-449
    • Wang, L.J.1    Lu, L.2    Zhang, F.R.3    Chen, Q.J.4    De Caterina, R.5    Shen, W.F.6
  • 53
    • 84896694901 scopus 로고    scopus 로고
    • Low levels of serum soluble receptors for advanced glycation end products, biomarkers for disease state: Myth or reality
    • Prasad, K. Low levels of serum soluble receptors for advanced glycation end products, biomarkers for disease state: myth or reality. Int. J. Angiol. 23, 11-16 (2014
    • (2014) Int. J. Angiol , vol.23 , pp. 11-16
    • Prasad, K.1
  • 54
    • 80052885987 scopus 로고    scopus 로고
    • Total soluble and endogenous secretory receptor for advanced glycation end products as predictive biomarkers of coronary heart disease risk in patients with type 2 diabetes: An analysis from the CARDS trial
    • Colhoun, H.M., et al. Total soluble and endogenous secretory receptor for advanced glycation end products as predictive biomarkers of coronary heart disease risk in patients with type 2 diabetes: an analysis from the CARDS trial. Diabetes 60, 2379-2385 (2011
    • (2011) Diabetes , vol.60 , pp. 2379-2385
    • Colhoun, H.M.1
  • 56
    • 84878260579 scopus 로고    scopus 로고
    • Glyco-oxidation and cardiovascular complications in type 2 diabetes: A clinical update
    • Piarulli, F., Sartore, G., & Lapolla, A. Glyco-oxidation and cardiovascular complications in type 2 diabetes: a clinical update. Acta Diabetol. 50, 101-110 (2013
    • (2013) Acta Diabetol , vol.50 , pp. 101-110
    • Piarulli, F.1    Sartore, G.2    Lapolla, A.3
  • 57
    • 84908023172 scopus 로고    scopus 로고
    • Switching to multiple daily injection therapy with glulisine improves glycaemic control, vascular damage and treatment satisfaction in basal insulin glargine-injected diabetic patients
    • Yanagisawa, K., et al. Switching to multiple daily injection therapy with glulisine improves glycaemic control, vascular damage and treatment satisfaction in basal insulin glargine-injected diabetic patients. Diabetes Metab. Res. Rev. 30, 693-700 (2014
    • (2014) Diabetes Metab. Res. Rev , vol.30 , pp. 693-700
    • Yanagisawa, K.1
  • 58
    • 84900849425 scopus 로고    scopus 로고
    • Comparison of effects of pioglitazone and glimepiride on plasma soluble RAGE and RAGE expression in peripheral mononuclear cells in type 2 diabetes: Randomized controlled trial (PioRAGE
    • Koyama, H., et al. Comparison of effects of pioglitazone and glimepiride on plasma soluble RAGE and RAGE expression in peripheral mononuclear cells in type 2 diabetes: randomized controlled trial (PioRAGE). Atherosclerosis 234, 329-334 (2014
    • (2014) Atherosclerosis , vol.234 , pp. 329-334
    • Koyama, H.1
  • 59
    • 80054051876 scopus 로고    scopus 로고
    • Clinical study of advanced glycation end products in ogyptian diabetic obese and nonobese patients
    • Amin, M.N., Mosa, A.A., & El-Shishtawy, M.M. Clinical study of advanced glycation end products in ogyptian diabetic obese and nonobese patients. Int. J. Biomed. Sci. IJBS 7, 191-200 (2011
    • (2011) Int. J. Biomed. Sci. IJBS , vol.7 , pp. 191-200
    • Amin, M.N.1    Mosa, A.A.2    El-Shishtawy, M.M.3
  • 60
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • Park, L., et al. Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat. Med. 4, 1025-1031 (1998
    • (1998) Nat. Med , vol.4 , pp. 1025-1031
    • Park, L.1
  • 61
    • 84880980969 scopus 로고    scopus 로고
    • The effect of soluble RAGE on inhibition of angiotensin II-mediated atherosclerosis in apolipoprotein e deficient mice
    • Lee, D., et al. The effect of soluble RAGE on inhibition of angiotensin II-mediated atherosclerosis in apolipoprotein E deficient mice. PloS One 8, e69669 (2013
    • (2013) PloS One , vol.8 , pp. e69669
    • Lee, D.1
  • 62
    • 0037180531 scopus 로고    scopus 로고
    • RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice
    • Bucciarelli, L.G., et al. RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice. Circulation 106, 2827-2835 (2002
    • (2002) Circulation , vol.106 , pp. 2827-2835
    • Bucciarelli, L.G.1
  • 63
    • 35248813974 scopus 로고    scopus 로고
    • Soluble RAGE blocks scavenger receptor CD36-mediated uptake of hypochlorite-modified low-density lipoprotein
    • Marsche, G., Weigle, B., Sattler, W., & Malle, E. Soluble RAGE blocks scavenger receptor CD36-mediated uptake of hypochlorite-modified low-density lipoprotein. FASEB J. 21, 3075-3082 (2007
    • (2007) FASEB J. , vol.21 , pp. 3075-3082
    • Marsche, G.1    Weigle, B.2    Sattler, W.3    Malle, E.4
  • 64
    • 2042454165 scopus 로고    scopus 로고
    • Use of topical sRAGE in diabetic wounds increases neovascularization and granulation tissue formation
    • discussion 22
    • Wear-Maggitti, K., Lee, J., Conejero, A., Schmidt, A.M., Grant, R., & Breitbart, A. Use of topical sRAGE in diabetic wounds increases neovascularization and granulation tissue formation. Ann. Plast. Surg. 52, 519-521; discussion 22 (2004
    • (2004) Ann. Plast. Surg , vol.52 , pp. 519-521
    • Wear-Maggitti, K.1    Lee, J.2    Conejero, A.3    Schmidt, A.M.4    Grant, R.5    Breitbart, A.6
  • 65
    • 0034880114 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation endproducts restores effective wound healing in diabetic mice
    • Goova, M.T., et al. Blockade of receptor for advanced glycation endproducts restores effective wound healing in diabetic mice. Am. J. Pathol. 159, 513-525 (2001
    • (2001) Am. J. Pathol , vol.159 , pp. 513-525
    • Goova, M.T.1
  • 66
    • 0037377697 scopus 로고    scopus 로고
    • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
    • Wendt, T.M., et al. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am. J. Pathol. 162, 1123-1137 (2003
    • (2003) Am. J. Pathol , vol.162 , pp. 1123-1137
    • Wendt, T.M.1
  • 67
    • 0141541794 scopus 로고    scopus 로고
    • The role of advanced glycation end products in retinal microvascular leukostasis
    • Moore, T.C., et al. The role of advanced glycation end products in retinal microvascular leukostasis. Invest. Ophthalmol. Visual Sci. 44, 4457-4464 (2003
    • (2003) Invest. Ophthalmol. Visual Sci , vol.44 , pp. 4457-4464
    • Moore, T.C.1
  • 68
    • 84901495081 scopus 로고    scopus 로고
    • Nepsilon-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesityinduced dysregulation of adipokine expression and insulin resistance
    • Gaens, K.H., et al. Nepsilon-(carboxymethyl)lysine-receptor for advanced glycation end product axis is a key modulator of obesityinduced dysregulation of adipokine expression and insulin resistance. Arterioscler. Thromb. Vasc. Biol. 34, 1199-1208 (2014
    • (2014) Arterioscler. Thromb. Vasc. Biol , vol.34 , pp. 1199-1208
    • Gaens, K.H.1
  • 69
    • 84856873812 scopus 로고    scopus 로고
    • Signal transduction in receptor for advanced glycation end products (RAGE): Solution structure of C-Terminal rage (ctRAGE) and its binding to mDia1
    • Rai, V., et al. Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-Terminal rage (ctRAGE) and its binding to mDia1. J. Biol. Chem. 287, 5133-5144 (2012
    • (2012) J. Biol. Chem , vol.287 , pp. 5133-5144
    • Rai, V.1
  • 70
    • 84861098989 scopus 로고    scopus 로고
    • Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways
    • Toure, F., et al. Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways. Circ. Res. 110, 1279-1293 (2012
    • (2012) Circ. Res , vol.110 , pp. 1279-1293
    • Toure, F.1
  • 71
    • 77954889408 scopus 로고    scopus 로고
    • Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages
    • Xu, Y., et al. Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. J. Biol. Chem. 285, 23233-23240 (2010
    • (2010) J. Biol. Chem , vol.285 , pp. 23233-23240
    • Xu, Y.1
  • 72
    • 79953214581 scopus 로고    scopus 로고
    • S100B protein stimulates microglia migration via RAGE-dependent upregulation of chemokine expression and release
    • Bianchi, R., Kastrisianaki, E., Giambanco, I., & Donato, R. S100B protein stimulates microglia migration via RAGE-dependent upregulation of chemokine expression and release. J. Biol. Chem. 286, 7214-7226 (2011
    • (2011) J. Biol. Chem , vol.286 , pp. 7214-7226
    • Bianchi, R.1    Kastrisianaki, E.2    Giambanco, I.3    Donato, R.4
  • 73
    • 0036305635 scopus 로고    scopus 로고
    • ROCK and Dia have opposing effects on adherens junctions downstream of Rho
    • Sahai, E., & Marshall, C.J. ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat. Cell Biol. 4, 408-415 (2002
    • (2002) Nat. Cell Biol , vol.4 , pp. 408-415
    • Sahai, E.1    Marshall, C.J.2
  • 74
    • 33645219720 scopus 로고    scopus 로고
    • Renal effects of a neutralising RAGE-Antibody in longterm streptozotocin-diabetic mice
    • Jensen, L.J., Denner, L., Schrijvers, B.F., Tilton, R.G., Rasch, R., & Flyvbjerg, A. Renal effects of a neutralising RAGE-Antibody in longterm streptozotocin-diabetic mice. J. Endocrinol. 188, 493-501 (2006
    • (2006) J. Endocrinol , vol.188 , pp. 493-501
    • Jensen, L.J.1    Denner, L.2    Schrijvers, B.F.3    Tilton, R.G.4    Rasch, R.5    Flyvbjerg, A.6
  • 75
    • 84878976908 scopus 로고    scopus 로고
    • Combinatorial library of improved peptide aptamers CLIPs to inhibit RAGE signal transduction in mammalian cells
    • Reverdatto, S., Rai, V., Xue, J., Burz, D.S., Schmidt, A.M., & Shekhtman, A. Combinatorial library of improved peptide aptamers, CLIPs to inhibit RAGE signal transduction in mammalian cells. PloS One 8, e65180 (2013
    • (2013) PloS One , vol.8 , pp. e65180
    • Reverdatto, S.1    Rai, V.2    Xue, J.3    Burz, D.S.4    Schmidt, A.M.5    Shekhtman, A.6
  • 76
    • 56149124859 scopus 로고    scopus 로고
    • RAGE ligation affects T cell activation and controls T cell differentiation
    • Chen, Y., et al. RAGE ligation affects T cell activation and controls T cell differentiation. J. Immunol. 181, 4272-4278 (2008
    • (2008) J. Immunol , vol.181 , pp. 4272-4278
    • Chen, Y.1
  • 77
    • 84859723641 scopus 로고    scopus 로고
    • A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
    • Deane, R., et al. A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. J. Clin. Invest. 122, 1377-1392 (2012
    • (2012) J. Clin. Invest , vol.122 , pp. 1377-1392
    • Deane, R.1
  • 78
    • 84937735945 scopus 로고    scopus 로고
    • Deoxycholic acid-modified polyethylenimine based nanocarriers for RAGE siRNA therapy in acute myocardial infarction
    • e-pub ahead of print
    • Ku, S.H., et al. Deoxycholic acid-modified polyethylenimine based nanocarriers for RAGE siRNA therapy in acute myocardial infarction. Arch. Pharm. Res.; e-pub ahead of print 2015.
    • (2015) Arch. Pharm. Res
    • Ku, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.