Increased accumulation of protein-bound N (carboxymethyl)lysine in tissues of healthy rats after chronic oral n (carboxymethyl)lysine

Journal of Agricultural and Food Chemistry

Volumn 63, Issue 5, 2015, Pages 1658-1663

  Li, Mei ^a   Zeng, Maomao ^a   He, Zhiyong ^a   Zheng, Zongping ^a   Qin, Fang ^a   Tao, Guanjun ^a   Zhang, Shuang ^a   Chen, Jie ^a,b  

^a State Key Laboratory of Food Science and Technology   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

advanced glycation end products; fasting blood glucose; N (carboxymethyl)lysine; serum markers; tissues

Indexed keywords

BLOOD; BODY FLUIDS; DRUG PRODUCTS; FIBER BRAGG GRATINGS; GLUCOSE; GLYCOSYLATION; HEALTH RISKS; HISTOLOGY; NUTRITION; PROTEINS; RATS; TISSUE; UREA;

ADVANCED GLYCATION END PRODUCTS; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BLOOD GLUCOSE; BLOOD UREA NITROGENS; CARBOXYMETHYL; POTENTIAL HEALTH RISKS; SERUM MARKERS;

AMINO ACIDS;

RATTUS;

LYSINE; N(6)-CARBOXYMETHYLLYSINE; PROTEIN; PROTEIN BINDING;

ANALOGS AND DERIVATIVES; ANIMAL; KIDNEY; LIVER; LUNG; MALE; METABOLISM; RAT; SPLEEN; SPRAGUE DAWLEY RAT;

ANIMALS; KIDNEY; LIVER; LUNG; LYSINE; MALE; PROTEIN BINDING; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN;

EID: 84922623834     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf505063t     Document Type: Article

References (47)

1. Singh, R.; Barden, A.; Mori, T.; Beilin, L. Advanced glycation end-products: A review Diabetologia 2001, 44, 129-146
2. Vitek, M. P.; Bhattacharya, K.; Glendening, J. M.; Stopa, E.; Vlassara, H.; Bucala, R.; Manogue, K.; Cerami, A. Advanced glycation end products contribute to amyloidosis in Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 1994, 91, 4766-4770
3. Takeuchi, M.; Yamagishi, S. I. Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimers disease Curr. Pharm. Des. 2008, 14, 973-978
4. Basta, G.; Schmidt, A. M.; De Caterina, R. Advanced glycation end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes Cardiovasc. Res. 2004, 63, 582-592
5. Vlassara, H.; Palace, M. R. Diabetes and advanced glycation endproducts J. Int. Med. 2002, 251, 87-101
6. ε-(carboxymethyl)lysine in hearts of diabetic patients: Generation and characterisation of a monoclonal anti-CML antibody Biochim. Biophys. Acta, Mol. Cell Res. 2004, 1636, 82-89
7. ε-(carboxymethyl) lysine and argpyrimidine Ann. N.Y. Acad. Sci. 2005, 1043, 725-733
8. Thornalley, P.; Battah, S.; Ahmed, N.; Karachalias, N.; Agalou, S.; Babaei-Jadidi, R.; Dawnay, A. Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry Biochem. J. 2003, 375, 581-592
9. Goldberg, T.; Cai, W.; Peppa, M.; Dardaine, V.; Baliga, B. S.; Uribarri, J.; Vlassara, H. Advanced glycoxidation end products in commonly consumed foods J. Am. Diet. Assoc. 2004, 104, 1287-1291
10. Uribarri, J.; Peppa, M.; Cai, W.; Goldberg, T.; Lu, M.; Baliga, S.; Vassalotti, J. A.; Vlassara, H. Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients Am. J. Kidney Dis. 2003, 42, 532-538
11. Vlassara, H.; Cai, W.; Crandall, J.; Goldberg, T.; Oberstein, R.; Dardaine, V.; Peppa, M.; Rayfield, E. J. Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy Proc. Natl. Acad. Sci. U. S. A. 2002, 99, 15596-15601
12. Koschinsky, T.; He, C. J.; Mitsuhashi, T.; Bucala, R.; Liu, C.; Buenting, C.; Heitmann, K.; Vlassara, H. Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic nephropathy Proc. Natl. Acad. Sci. U. S. A. 1997, 94, 6474-6479
13. Delgado-Andrade, C. Maillard reaction products: Some considerations on their health effects Clin. Chem. Lab. Med. 2014, 52, 53-60
14. ε-carboxymethyllysine: A new Maillard reaction product in rat urine J. Agric. Food Chem. 1987, 35, 427-431
15. ε-(carboxymethyl) lysine in foods and related systems Ann. N.Y. Acad. Sci. 2008, 1126, 20-24
16. Chao, P. C.; Hsu, C. C.; Yin, M. C. Analysis of glycative products in sauces and sauce-treated foods Food Chem. 2009, 113, 262-266
17. Uribarri, J.; Woodruff, S.; Goodman, S.; Cai, W.; Chen, X.; Pyzik, R.; Yong, A.; Striker, G. E.; Vlassara, H. Advanced glycation end products in foods and a practical guide to their reduction in the diet J. Am. Diet. Assoc. 2010, 110, 911-916
18. Zhang, G.; Huang, G.; Xiao, L.; Mitchell, A. E. Determination of advanced glycation endproducts by LC-MS/MS in raw and roasted almonds (Prunus dulcis) J. Agric. Food Chem. 2011, 59, 12037-12046
19. ε-(Carboxymethyl) lysine content of foods commonly consumed in a Western style diet Food Chem. 2012, 131, 170-174
20. ε-(carboxymethyl) lysine levels in patients with type 2 diabetes: Role of renal function Am. J. Kidney Dis. 2001, 38, 785-791
21. ε-(carboxymethyl) lysine excretion in normal and diabetic subjects J. Chromatogr., B 2003, 794, 273-280
22. ε-(carboxyethyl) lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry Clin. Chem. 2004, 50, 1222-1228
23. ε-carboxymethyllysine in casein model systems Food (Weinheim, Germany) 2001, 45, 218-221
24. ε-(Carboxymethyl) lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression J. Biol. Chem. 1999, 274, 31740-31749
25. Uribarri, J.; Cai, W.; Peppa, M.; Goodman, S.; Ferrucci, L.; Striker, G.; Vlassara, H. Circulating glycotoxins and dietary advanced glycation endproducts: Two links to inflammatory response, oxidative stress, and aging J. Gerontol., Ser. A 2007, 62, 427-433
26. Somoza, V.; Lindenmeier, M.; Hofmann, T.; Frank, O.; Erbersdobler, H. F.; Baynes, J. W.; Thorpe, S. R.; Heidland, A.; Zill, H.; Bek, S.; Huber, J.; Weigle, T.; Scheidler, S.; Busch, A. E.; Šebeková, K. Dietary bread crust advanced glycation end products bind to the receptor for AGEs in HEK-293 kidney cells but are rapidly excreted after oral administration to healthy and subtotally nephrectomized rats Ann. N.Y. Acad. Sci. 2005, 1043, 492-500
27. Tanji, N.; Markowitz, G. S.; Fu, C.; Kislinger, T.; Taguchi, A.; Pischetsrieder, M.; Stern, D.; Schmidt, M.; Dagati, V. D. Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease J. Am. Soc. Nephrol. 2000, 11, 1656-1666
28. ε-(Carboxymethyl) lysine in atherosclerotic vascular lesions as a marker for local oxidative stress Atherosclerosis 1999, 144, 41-47
29. ε-carboxymethyl-lysine after consumption of AGEs from bread crust Food Funct. 2013, 4, 1032-1039
30. ε-carboxymethyl-lysine accumulation in the cardiac tissue and tendons of rats J. Agric. Food Chem. 2014, 62, 6001-6006
31. ε-carboxymethyllysine in rats Amino Acids 2013, 44, 1441-1449
32. Somoza, V.; Wenzel, E.; Weiss, C.; Clawin-Rädecker, I.; Grübel, N.; Erbersdobler, H. F. Dose-dependent utilisation of casein-linked lysinoalanine, N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine in rats Mol. Nutr. Food Res. 2006, 50, 833-841
33. Dhar, A.; Dhar, I.; Jiang, B.; Desai, K. M.; Wu, L. Chronic methylglyoxal infusion by minipump causes pancreatic β-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats Diabetes 2011, 60, 899-908
34. Tessier, F. J.; Birlouez-Aragon, I. Health effects of dietary Maillard reaction products: The results of ICARE and other studies Amino Acids 2012, 42, 1119-1131
35. Schwedler, S. B.; Metzger, T.; Schinzel, R.; Wanner, C. Advanced glycation end products and mortality in hemodialysis patients Kidney Int. 2002, 62, 301-310
36. ε-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension Am. J. Kidney Dis. 2006, 48 (4) 571-579
37. Kellow, N. J.; Savige, G. S. Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: A systematic review Eur. J. Clin. Nutr. 2013, 67, 239-248
38. Higuchi, H.; Gores, G. J. Mechanisms of liver injury: An overview Curr. Mol. Med. 2003, 3, 483-490
39. ε-carboxyethyllysine (CEL) Food (Weinheim, Germany) 2001, 45, 182-188
40. ε-(carboxymethyl) lysine by the mouse liver reticulo-endothelial system: Implications for pathophysiology Biochem. Biophys. Res. Commun. 2003, 309, 786-791
41. ε-(carboxymethyl) lysine in human tissues in diabetes and aging J. Clin. Invest. 1997, 99, 457-468
42. Baynes, J. W. Role of oxidative stress in development of complications in diabetes Diabetes 1991, 40, 405-412
43. Cai, W.; He, J. C.; Zhu, L.; Chen, X.; Zheng, F.; Striker, G. E.; Vlassara, H. Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan Am. J. Pathol. 2008, 173, 327-336
44. Finco, D. R.; Duncan, J. R. Evaluation of blood urea nitrogen and serum creatinine concentrations as indicators of renal dysfunction: A study of 111 cases and a review of related literature J. Am. Vet. Med. Assoc. 1976, 168, 593-601
45. Williams, P.; Lopez, H.; Britt, D.; Chan, C.; Ezrin, A.; Hottendorf, R. Characterization of renal ischemia-reperfusion injury in rats J. Pharmacol. Toxicol. Methods 1997, 37, 1-7
46. Ramaiah, S. K. A toxicologist guide to the diagnostic interpretation of hepatic biochemical parameters Food Chem. Toxicol. 2007, 45, 1551-1557
47. Solter, P. F. Clinical pathology approaches to hepatic injury Toxicol. Pathol. 2005, 33, 9-16