-
1
-
-
84881276734
-
Colorectal cancer: molecular mutations and polymorphisms
-
1 [PMID: 23717813]
-
1 Sameer AS. Colorectal cancer: molecular mutations and polymorphisms. Front Oncol2013; 3: 114 [PMID: 23717813 DOI: 10.3389/fonc.2013.00114]
-
Front Oncol2013
, vol.3
, pp. 114
-
-
Sameer, AS.1
-
2
-
-
0347126338
-
Primary and secondary prevention in colorectal cancer
-
2 [PMID: 14968941]
-
2 Vainio H, Miller AB. Primary and secondary prevention in colorectal cancer. Acta Oncol2003; 42: 809-815 [PMID: 14968941]
-
Acta Oncol2003
, vol.42
, pp. 809-815
-
-
Vainio, H1
Miller, AB.2
-
4
-
-
84884189727
-
Long-term colorectal-cancer incidence and mortality after lower endoscopy
-
4 [PMID: 24047059]
-
4 Nishihara R, Wu K, Lochhead P, Morikawa T, Liao X, Qian ZR, Inamura K, Kim SA, Kuchiba A, Yamauchi M, Imamura Y, Willett WC, Rosner BA, Fuchs CS, Giovannucci E, Ogino S, Chan AT. Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med2013; 369: 1095-1105 [PMID: 24047059 DOI: 10.1056/NEJMoa1301969]
-
N Engl J Med2013
, vol.369
, pp. 1095-1105
-
-
Nishihara, R1
Wu, K2
Lochhead, P3
Morikawa, T4
Liao, X5
Qian, ZR6
Inamura, K7
Kim, SA8
Kuchiba, A9
Yamauchi, M10
Imamura, Y11
Willett, WC12
Rosner, BA13
Fuchs, CS14
Giovannucci, E15
Ogino, S16
Chan, AT.17
-
5
-
-
84884183059
-
Long-term mortality after screening for colorectal cancer
-
5 [PMID: 24047060]
-
5 Shaukat A, Mongin SJ, Geisser MS, Lederle FA, Bond JH, Mandel JS, Church TR. Long-term mortality after screening for colorectal cancer. N Engl J Med2013; 369: 1106-1114 [PMID: 24047060 DOI: 10.1056/NEJMoa1300720]
-
N Engl J Med2013
, vol.369
, pp. 1106-1114
-
-
Shaukat, A1
Mongin, SJ2
Geisser, MS3
Lederle, FA4
Bond, JH5
Mandel, JS6
Church, TR.7
-
6
-
-
84866551409
-
European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition–Quality assurance in pathology in colorectal cancer screening and diagnosis
-
6 Suppl 3: [PMID: 23012115]
-
6 Quirke P, Risio M, Lambert R, von Karsa L, Vieth M. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition–Quality assurance in pathology in colorectal cancer screening and diagnosis. Endoscopy2012; 44 Suppl 3: SE116-SE130 [PMID: 23012115]
-
Endoscopy2012
, vol.44
, pp. SE116-SE130
-
-
Quirke, P1
Risio, M2
Lambert, R3
von Karsa, L4
Vieth, M.5
-
8
-
-
0031811367
-
Colorectal cancer in patients under forty: presentation and outcome
-
8 ; discussion 567-568 [PMID: 9619179]
-
8 Parramore JB, Wei JP, Yeh KA. Colorectal cancer in patients under forty: presentation and outcome. Am Surg1998; 64: 563-567; discussion 567-568 [PMID: 9619179]
-
Am Surg1998
, vol.64
, pp. 563-567
-
-
Parramore, JB1
Wei, JP2
Yeh, KA.3
-
9
-
-
37149041833
-
Molecular classification and correlates in colorectal cancer
-
9 [PMID: 18165277]
-
9 Ogino S, Goel A. Molecular classification and correlates in colorectal cancer. J Mol Diagn2008; 10: 13-27 [PMID: 18165277 DOI: 10.2353/jmoldx.2008.070082]
-
J Mol Diagn2008
, vol.10
, pp. 13-27
-
-
Ogino, S1
Goel, A.2
-
10
-
-
77955722606
-
Approach to early-onset colorectal cancer: clinicopathological, familial, molecular and immunohistochemical characteristics
-
10 [PMID: 20677343]
-
10 Perea J, Alvaro E, Rodríguez Y, Gravalos C, Sánchez-Tomé E, Rivera B, Colina F, Carbonell P, González-Sarmiento R, Hidalgo M, Urioste M. Approach to early-onset colorectal cancer: clinicopathological, familial, molecular and immunohistochemical characteristics. World J Gastroenterol2010; 16: 3697-3703 [PMID: 20677343]
-
World J Gastroenterol2010
, vol.16
, pp. 3697-3703
-
-
Perea, J1
Alvaro, E2
Rodríguez, Y3
Gravalos, C4
Sánchez-Tomé, E5
Rivera, B6
Colina, F7
Carbonell, P8
González-Sarmiento, R9
Hidalgo, M10
Urioste, M.11
-
11
-
-
27744589776
-
Molecular genetic alterations and clinical features in early-onset colorectal carcinomas and their role for the recognition of hereditary cancer syndromes
-
11 [PMID: 16181381]
-
11 Losi L, Di Gregorio C, Pedroni M, Ponti G, Roncucci L, Scarselli A, Genuardi M, Baglioni S, Marino M, Rossi G, Benatti P, Maffei S, Menigatti M, Roncari B, Ponz de Leon M. Molecular genetic alterations and clinical features in early-onset colorectal carcinomas and their role for the recognition of hereditary cancer syndromes. Am J Gastroenterol2005; 100: 2280-2287 [PMID: 16181381]
-
Am J Gastroenterol2005
, vol.100
, pp. 2280-2287
-
-
Losi, L1
Di Gregorio, C2
Pedroni, M3
Ponti, G4
Roncucci, L5
Scarselli, A6
Genuardi, M7
Baglioni, S8
Marino, M9
Rossi, G10
Benatti, P11
Maffei, S12
Menigatti, M13
Roncari, B14
Ponz de Leon, M.15
-
12
-
-
33748636460
-
Colorectal cancer in U.S. adults younger than 50 years of age, 1998-2001
-
12 [PMID: 16862554]
-
12 Fairley TL, Cardinez CJ, Martin J, Alley L, Friedman C, Edwards B, Jamison P. Colorectal cancer in U.S. adults younger than 50 years of age, 1998-2001. Cancer2006; 107: 1153-1161 [PMID: 16862554]
-
Cancer2006
, vol.107
, pp. 1153-1161
-
-
Fairley, TL1
Cardinez, CJ2
Martin, J3
Alley, L4
Friedman, C5
Edwards, B6
Jamison, P.7
-
13
-
-
33847212827
-
Colorectal cancer localization in young patients: should we expand the screening program?
-
13 [PMID: 17245629]
-
13 Savas N, Dagli U, Akbulut S, Yuksel O, Sahin B. Colorectal cancer localization in young patients: should we expand the screening program? Dig Dis Sci2007; 52: 798-802 [PMID: 17245629]
-
Dig Dis Sci2007
, vol.52
, pp. 798-802
-
-
Savas, N1
Dagli, U2
Akbulut, S3
Yuksel, O4
Sahin, B.5
-
14
-
-
84857411702
-
Young-onset colorectal cancer: is it time to pay attention?
-
14 [PMID: 22157065]
-
14 You YN, Xing Y, Feig BW, Chang GJ, Cormier JN. Young-onset colorectal cancer: is it time to pay attention? Arch Intern Med2012; 172: 287-289 [PMID: 22157065 DOI: 10.1001/archinternmed.2011. 602]
-
Arch Intern Med2012
, vol.172
, pp. 287-289
-
-
You, YN1
Xing, Y2
Feig, BW3
Chang, GJ4
Cormier, JN.5
-
15
-
-
0033946516
-
Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes
-
15 [PMID: 10861498]
-
15 Calin GA, Gafà R, Tibiletti MG, Herlea V, Becheanu G, Cavazzini L, Barbanti-Brodano G, Nenci I, Negrini M, Lanza G. Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes. Int J Cancer2000; 89: 230-235 [PMID: 10861498]
-
Int J Cancer2000
, vol.89
, pp. 230-235
-
-
Calin, GA1
Gafà, R2
Tibiletti, MG3
Herlea, V4
Becheanu, G5
Cavazzini, L6
Barbanti-Brodano, G7
Nenci, I8
Negrini, M9
Lanza, G.10
-
16
-
-
84918585451
-
Early-onset colorectal cancer: a separate subset of colorectal cancer
-
16 [PMID: 25516639]
-
16 Silla IO, Rueda D, Rodríguez Y, García JL, de la Cruz Vigo F, Perea J. Early-onset colorectal cancer: a separate subset of colorectal cancer. World J Gastroenterol2014; 20: 17288-17296 [PMID: 25516639 DOI: 10.3748/wjg.v20.i46.17288]
-
World J Gastroenterol2014
, vol.20
, pp. 17288-17296
-
-
Silla, IO1
Rueda, D2
Rodríguez, Y3
García, JL4
de la Cruz Vigo, F5
Perea, J.6
-
17
-
-
84959871135
-
Practical genetics of colorectal cancer
-
17 [PMID: 25841492]
-
17 Lynch HT, Shaw TG. Practical genetics of colorectal cancer. Chin Clin Oncol2013; 2: 12 [PMID: 25841492 DOI: 10.3978/j.issn.2304-3865.2013.03.04]
-
Chin Clin Oncol2013
, vol.2
, pp. 12
-
-
Lynch, HT1
Shaw, TG.2
-
18
-
-
57449097359
-
Feasibility of screening for Lynch syndrome among patients with colorectal cancer
-
18 [PMID: 18809606]
-
18 Hampel H, Frankel WL, Martin E, Arnold M, Khanduja K, Kuebler P, Clendenning M, Sotamaa K, Prior T, Westman JA, Panescu J, Fix D, Lockman J, LaJeunesse J, Comeras I, de la Chapelle A. Feasibility of screening for Lynch syndrome among patients with colorectal cancer. J Clin Oncol2008; 26: 5783-5788 [PMID: 18809606 DOI: 10.1200/JCO.2008.17.5950]
-
J Clin Oncol2008
, vol.26
, pp. 5783-5788
-
-
Hampel, H1
Frankel, WL2
Martin, E3
Arnold, M4
Khanduja, K5
Kuebler, P6
Clendenning, M7
Sotamaa, K8
Prior, T9
Westman, JA10
Panescu, J11
Fix, D12
Lockman, J13
LaJeunesse, J14
Comeras, I15
de la Chapelle, A.16
-
19
-
-
0031551963
-
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines
-
19 [PMID: 9392616]
-
19 Rodriguez-Bigas MA, Boland CR, Hamilton SR, Henson DE, Jass JR, Khan PM, Lynch H, Perucho M, Smyrk T, Sobin L, Srivastava S. A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst1997; 89: 1758-1762 [PMID: 9392616]
-
J Natl Cancer Inst1997
, vol.89
, pp. 1758-1762
-
-
Rodriguez-Bigas, MA1
Boland, CR2
Hamilton, SR3
Henson, DE4
Jass, JR5
Khan, PM6
Lynch, H7
Perucho, M8
Smyrk, T9
Sobin, L10
Srivastava, S.11
-
20
-
-
0033063711
-
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC
-
20 [PMID: 10348829]
-
20 Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology1999; 116: 1453-1456 [PMID: 10348829]
-
Gastroenterology1999
, vol.116
, pp. 1453-1456
-
-
Vasen, HF1
Watson, P2
Mecklin, JP3
Lynch, HT.4
-
21
-
-
10744233937
-
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
-
21 [PMID: 14970275]
-
21 Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Rüschoff J, Fishel R, Lindor NM, Burgart LJ, Hamelin R, Hamilton SR, Hiatt RA, Jass J, Lindblom A, Lynch HT, Peltomaki P, Ramsey SD, Rodriguez-Bigas MA, Vasen HF, Hawk ET, Barrett JC, Freedman AN, Srivastava S. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst2004; 96: 261-268 [PMID: 14970275]
-
J Natl Cancer Inst2004
, vol.96
, pp. 261-268
-
-
Umar, A1
Boland, CR2
Terdiman, JP3
Syngal, S4
de la Chapelle, A5
Rüschoff, J6
Fishel, R7
Lindor, NM8
Burgart, LJ9
Hamelin, R10
Hamilton, SR11
Hiatt, RA12
Jass, J13
Lindblom, A14
Lynch, HT15
Peltomaki, P16
Ramsey, SD17
Rodriguez-Bigas, MA18
Vasen, HF19
Hawk, ET20
Barrett, JC21
Freedman, AN22
Srivastava, S.23
more..
-
22
-
-
73949154143
-
Colorectal cancer due to defciency in DNA mismatch repair function: a review
-
22 [PMID: 19851131]
-
22 Bellizzi AM, Frankel WL. Colorectal cancer due to defciency in DNA mismatch repair function: a review. Adv Anat Pathol2009; 16: 405-417 [PMID: 19851131 DOI: 10.1097/PAP.0b013e3181bb6bdc]
-
Adv Anat Pathol2009
, vol.16
, pp. 405-417
-
-
Bellizzi, AM1
Frankel, WL.2
-
23
-
-
78650183976
-
Analysis of mismatch repair gene mutations in Turkish HNPCC patients
-
23 [PMID: 20373145]
-
23 Tunca B, Pedroni M, Cecener G, Egeli U, Borsi E, Zorluoglu A, Di Gregorio C, Yilmazlar T, Yerci O, de Leon MP. Analysis of mismatch repair gene mutations in Turkish HNPCC patients. Fam Cancer2010; 9: 365-376 [PMID: 20373145 DOI: 10.1007/s10689-010-9336-7]
-
Fam Cancer2010
, vol.9
, pp. 365-376
-
-
Tunca, B1
Pedroni, M2
Cecener, G3
Egeli, U4
Borsi, E5
Zorluoglu, A6
Di Gregorio, C7
Yilmazlar, T8
Yerci, O9
de Leon, MP.10
-
24
-
-
79958146180
-
Identification and surveillance of 19 Lynch syndrome families in southern Italy: report of six novel germline mutations and a common founder mutation
-
24 [PMID: 21286823]
-
24 Lastella P, Patruno M, Forte G, Montanaro A, Di Gregorio C, Sabbà C, Suppressa P, Piepoli A, Panza A, Andriulli A, Resta N, Stella A. Identification and surveillance of 19 Lynch syndrome families in southern Italy: report of six novel germline mutations and a common founder mutation. Fam Cancer2011; 10: 285-295 [PMID: 21286823 DOI: 10.1007/s10689-011-9419-0]
-
Fam Cancer2011
, vol.10
, pp. 285-295
-
-
Lastella, P1
Patruno, M2
Forte, G3
Montanaro, A4
Di Gregorio, C5
Sabbà, C6
Suppressa, P7
Piepoli, A8
Panza, A9
Andriulli, A10
Resta, N11
Stella, A.12
-
25
-
-
84893334227
-
Germline mutation and protein expression analysis of mismatch repair genes MSH6 and PMS2 in Malaysian Lynch syndrome patients
-
25 [PMID: 24072394]
-
25 Zahary MN, Kaur G, Hassan MR, Sidek AS, Singh H, Yeh LY, Ankathil R. Germline mutation and protein expression analysis of mismatch repair genes MSH6 and PMS2 in Malaysian Lynch syndrome patients. Int J Colorectal Dis2014; 29: 261-262 [PMID: 24072394 DOI: 10.1007/s00384-013-1770-1]
-
Int J Colorectal Dis2014
, vol.29
, pp. 261-262
-
-
Zahary, MN1
Kaur, G2
Hassan, MR3
Sidek, AS4
Singh, H5
Yeh, LY6
Ankathil, R.7
-
26
-
-
84941022692
-
Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome
-
26 [PMID: 25782445]
-
26 Cruz-Correa M, Diaz-Algorri Y, Pérez-Mayoral J, Suleiman-Suleiman W, Del Mar Gonzalez-Pons M, Bertrán C, Casellas N, Rodríguez N, Pardo S, Rivera K, Mosquera R, Rodriguez-Quilichini S. Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome. Fam Cancer2015; 14: 415-425 [PMID: 25782445 DOI: 10.1007/s10689-015-9795-y]
-
Fam Cancer2015
, vol.14
, pp. 415-425
-
-
Cruz-Correa, M1
Diaz-Algorri, Y2
Pérez-Mayoral, J3
Suleiman-Suleiman, W4
Del Mar Gonzalez-Pons, M5
Bertrán, C6
Casellas, N7
Rodríguez, N8
Pardo, S9
Rivera, K10
Mosquera, R11
Rodriguez-Quilichini, S.12
-
27
-
-
64649096900
-
Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803
-
27 [PMID: 19273709]
-
27 Bertagnolli MM, Niedzwiecki D, Compton CC, Hahn HP, Hall M, Damas B, Jewell SD, Mayer RJ, Goldberg RM, Saltz LB, Warren RS, Redston M. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. J Clin Oncol2009; 27: 1814-1821 [PMID: 19273709 DOI: 10.1200/JCO.2008.18.2071]
-
J Clin Oncol2009
, vol.27
, pp. 1814-1821
-
-
Bertagnolli, MM1
Niedzwiecki, D2
Compton, CC3
Hahn, HP4
Hall, M5
Damas, B6
Jewell, SD7
Mayer, RJ8
Goldberg, RM9
Saltz, LB10
Warren, RS11
Redston, M.12
-
28
-
-
84940004205
-
Microsatellite instability: an update
-
28 [PMID: 25701956]
-
28 Yamamoto H, Imai K. Microsatellite instability: an update. Arch Toxicol2015; 89: 899-921 [PMID: 25701956 DOI: 10.1007/s00204-015-1474-0]
-
Arch Toxicol2015
, vol.89
, pp. 899-921
-
-
Yamamoto, H1
Imai, K.2
-
29
-
-
75549089295
-
SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology
-
29 [PMID: 19820113]
-
29 Woerner SM, Yuan YP, Benner A, Korff S, von Knebel Doeberitz M, Bork P. SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology. Nucleic Acids Res2010; 38: D682-D689 [PMID: 19820113 DOI: 10.1093/nar/gkp839]
-
Nucleic Acids Res2010
, vol.38
, pp. D682-D689
-
-
Woerner, SM1
Yuan, YP2
Benner, A3
Korff, S4
von Knebel Doeberitz, M5
Bork, P.6
-
30
-
-
84929492513
-
Mismatch repair-defcient crypt foci in Lynch syndrome–molecular alterations and association with clinical parameters
-
30 [PMID: 25816162]
-
30 Staffa L, Echterdiek F, Nelius N, Benner A, Werft W, Lahrmann B, Grabe N, Schneider M, Tariverdian M, von Knebel Doeberitz M, Bläker H, Kloor M. Mismatch repair-defcient crypt foci in Lynch syndrome–molecular alterations and association with clinical parameters. PLoS One2015; 10: e0121980 [PMID: 25816162 DOI: 10.1371/journal.pone.0121980]
-
PLoS One2015
, vol.10
, pp. e0121980
-
-
Staffa, L1
Echterdiek, F2
Nelius, N3
Benner, A4
Werft, W5
Lahrmann, B6
Grabe, N7
Schneider, M8
Tariverdian, M9
von Knebel Doeberitz, M10
Bläker, H11
Kloor, M.12
-
31
-
-
69549111048
-
Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations
-
31 [PMID: 19503063]
-
31 Tougeron D, Fauquembergue E, Rouquette A, Le Pessot F, Sesboüé R, Laurent M, Berthet P, Mauillon J, Di Fiore F, Sabourin JC, Michel P, Tosi M, Frébourg T, Latouche JB. Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations. Mod Pathol2009; 22: 1186-1195 [PMID: 19503063 DOI: 10.1038/modpathol.2009.80]
-
Mod Pathol2009
, vol.22
, pp. 1186-1195
-
-
Tougeron, D1
Fauquembergue, E2
Rouquette, A3
Le Pessot, F4
Sesboüé, R5
Laurent, M6
Berthet, P7
Mauillon, J8
Di Fiore, F9
Sabourin, JC10
Michel, P11
Tosi, M12
Frébourg, T13
Latouche, JB.14
-
32
-
-
12244301669
-
Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-defcient cancer cells
-
32 [PMID: 15563124]
-
32 Schwitalle Y, Linnebacher M, Ripberger E, Gebert J, von Knebel Doeberitz M. Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-defcient cancer cells. Cancer Immun2004; 4: 14 [PMID: 15563124]
-
Cancer Immun2004
, vol.4
, pp. 14
-
-
Schwitalle, Y1
Linnebacher, M2
Ripberger, E3
Gebert, J4
von Knebel Doeberitz, M.5
-
33
-
-
84887924524
-
The landscape of microsatellite instability in colorectal and endometrial cancer genomes
-
33 [PMID: 24209623]
-
33 Kim TM, Laird PW, Park PJ. The landscape of microsatellite instability in colorectal and endometrial cancer genomes. Cell2013; 155: 858-868 [PMID: 24209623 DOI: 10.1016/j.cell.2013.10.015]
-
Cell2013
, vol.155
, pp. 858-868
-
-
Kim, TM1
Laird, PW2
Park, PJ.3
-
34
-
-
0029066689
-
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
-
34 [PMID: 7761852]
-
34 Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science1995; 268: 1336-1338 [PMID: 7761852]
-
Science1995
, vol.268
, pp. 1336-1338
-
-
Markowitz, S1
Wang, J2
Myeroff, L3
Parsons, R4
Sun, L5
Lutterbaugh, J6
Fan, RS7
Zborowska, E8
Kinzler, KW9
Vogelstein, B.10
-
35
-
-
84930031024
-
Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2
-
35 e8 [PMID: 25736321]
-
35 de Miranda NF, van Dinther M, van den Akker BE, van Wezel T, ten Dijke P, Morreau H. Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2. Gastroenterology2015; 148: 1427-1437.e8 [PMID: 25736321 DOI: 10.1053/j.gastro.2015.02.052]
-
Gastroenterology2015
, vol.148
, pp. 1427-1437
-
-
de Miranda, NF1
van Dinther, M2
van den Akker, BE3
van Wezel, T4
ten Dijke, P5
Morreau, H.6
-
36
-
-
84897400369
-
Epigenetic mechanisms in the pathogenesis of Lynch syndrome
-
36 [PMID: 24443998]
-
36 Peltomäki P. Epigenetic mechanisms in the pathogenesis of Lynch syndrome. Clin Genet2014; 85: 403-412 [PMID: 24443998 DOI: 10.1111/cge.12349]
-
Clin Genet2014
, vol.85
, pp. 403-412
-
-
Peltomäki, P.1
-
37
-
-
34447132378
-
Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach
-
37 [PMID: 17260015]
-
37 Ollikainen M, Hannelius U, Lindgren CM, Abdel-Rahman WM, Kere J, Peltomäki P. Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach. Oncogene2007; 26: 4541-4549 [PMID: 17260015]
-
Oncogene2007
, vol.26
, pp. 4541-4549
-
-
Ollikainen, M1
Hannelius, U2
Lindgren, CM3
Abdel-Rahman, WM4
Kere, J5
Peltomäki, P.6
-
38
-
-
77951049336
-
Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers
-
38 [PMID: 20388775]
-
38 Nagasaka T, Rhees J, Kloor M, Gebert J, Naomoto Y, Boland CR, Goel A. Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers. Cancer Res2010; 70: 3098-3108 [PMID: 20388775 DOI: 10.1158/0008-5472. CAN-09-3290]
-
Cancer Res2010
, vol.70
, pp. 3098-3108
-
-
Nagasaka, T1
Rhees, J2
Kloor, M3
Gebert, J4
Naomoto, Y5
Boland, CR6
Goel, A.7
-
39
-
-
0037099602
-
A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor
-
39 [PMID: 12124320]
-
39 Gazzoli I, Loda M, Garber J, Syngal S, Kolodner RD. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res2002; 62: 3925-3928 [PMID: 12124320]
-
Cancer Res2002
, vol.62
, pp. 3925-3928
-
-
Gazzoli, I1
Loda, M2
Garber, J3
Syngal, S4
Kolodner, RD.5
-
40
-
-
10744230172
-
Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability
-
40 [PMID: 15017620]
-
40 Miyakura Y, Sugano K, Akasu T, Yoshida T, Maekawa M, Saitoh S, Sasaki H, Nomizu T, Konishi F, Fujita S, Moriya Y, Nagai H. Extensive but hemiallelic methylation of the hMLH1 promoter region in early-onset sporadic colon cancers with microsatellite instability. Clin Gastroenterol Hepatol2004; 2: 147-156 [PMID: 15017620]
-
Clin Gastroenterol Hepatol2004
, vol.2
, pp. 147-156
-
-
Miyakura, Y1
Sugano, K2
Akasu, T3
Yoshida, T4
Maekawa, M5
Saitoh, S6
Sasaki, H7
Nomizu, T8
Konishi, F9
Fujita, S10
Moriya, Y11
Nagai, H.12
-
41
-
-
33846973361
-
Inheritance of a cancer-associated MLH1 germ-line epimutation
-
41 [PMID: 17301300]
-
41 Hitchins MP, Wong JJ, Suthers G, Suter CM, Martin DI, Hawkins NJ, Ward RL. Inheritance of a cancer-associated MLH1 germ-line epimutation. N Engl J Med2007; 356: 697-705 [PMID: 17301300]
-
N Engl J Med2007
, vol.356
, pp. 697-705
-
-
Hitchins, MP1
Wong, JJ2
Suthers, G3
Suter, CM4
Martin, DI5
Hawkins, NJ6
Ward, RL.7
-
42
-
-
33749122904
-
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
-
42 [PMID: 16951683]
-
42 Chan TL, Yuen ST, Kong CK, Chan YW, Chan AS, Ng WF, Tsui WY, Lo MW, Tam WY, Li VS, Leung SY. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat Genet2006; 38: 1178-1183 [PMID: 16951683]
-
Nat Genet2006
, vol.38
, pp. 1178-1183
-
-
Chan, TL1
Yuen, ST2
Kong, CK3
Chan, YW4
Chan, AS5
Ng, WF6
Tsui, WY7
Lo, MW8
Tam, WY9
Li, VS10
Leung, SY.11
-
43
-
-
58149144567
-
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3’ exons of TACSTD1
-
43 [PMID: 19098912]
-
43 Ligtenberg MJ, Kuiper RP, Chan TL, Goossens M, Hebeda KM, Voorendt M, Lee TY, Bodmer D, Hoenselaar E, Hendriks-Cornelissen SJ, Tsui WY, Kong CK, Brunner HG, van Kessel AG, Yuen ST, van Krieken JH, Leung SY, Hoogerbrugge N. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3’ exons of TACSTD1. Nat Genet2009; 41: 112-117 [PMID: 19098912 DOI: 10.1038/ng.283]
-
Nat Genet2009
, vol.41
, pp. 112-117
-
-
Ligtenberg, MJ1
Kuiper, RP2
Chan, TL3
Goossens, M4
Hebeda, KM5
Voorendt, M6
Lee, TY7
Bodmer, D8
Hoenselaar, E9
Hendriks-Cornelissen, SJ10
Tsui, WY11
Kong, CK12
Brunner, HG13
van Kessel, AG14
Yuen, ST15
van Krieken, JH16
Leung, SY17
Hoogerbrugge, N.18
-
44
-
-
79952754996
-
Recurrence and variability of germline EPCAM deletions in Lynch syndrome
-
44 [PMID: 21309036]
-
44 Kuiper RP, Vissers LE, Venkatachalam R, Bodmer D, Hoenselaar E, Goossens M, Haufe A, Kamping E, Niessen RC, Hogervorst FB, Gille JJ, Redeker B, Tops CM, van Gijn ME, van den Ouweland AM, Rahner N, Steinke V, Kahl P, Holinski-Feder E, Morak M, Kloor M, Stemmler S, Betz B, Hutter P, Bunyan DJ, Syngal S, Culver JO, Graham T, Chan TL, Nagtegaal ID, van Krieken JH, Schackert HK, Hoogerbrugge N, van Kessel AG, Ligtenberg MJ. Recurrence and variability of germline EPCAM deletions in Lynch syndrome. Hum Mutat2011; 32: 407-414 [PMID: 21309036 DOI: 10.1002/humu.21446]
-
Hum Mutat2011
, vol.32
, pp. 407-414
-
-
Kuiper, RP1
Vissers, LE2
Venkatachalam, R3
Bodmer, D4
Hoenselaar, E5
Goossens, M6
Haufe, A7
Kamping, E8
Niessen, RC9
Hogervorst, FB10
Gille, JJ11
Redeker, B12
Tops, CM13
van Gijn, ME14
van den Ouweland, AM15
Rahner, N16
Steinke, V17
Kahl, P18
Holinski-Feder, E19
Morak, M20
Kloor, M21
Stemmler, S22
Betz, B23
Hutter, P24
Bunyan, DJ25
Syngal, S26
Culver, JO27
Graham, T28
Chan, TL29
Nagtegaal, ID30
van Krieken, JH31
Schackert, HK32
Hoogerbrugge, N33
van Kessel, AG34
Ligtenberg, MJ.35
more..
-
45
-
-
84888437742
-
How microRNAs infuence both hereditary and infammatory-mediated colon cancers
-
45 [PMID: 24042167]
-
45 Hutchison J, Cohen Z, Onyeagucha BC, Funk J, Nelson MA. How microRNAs infuence both hereditary and infammatory-mediated colon cancers. Cancer Genet2013; 206: 309-316 [PMID: 24042167 DOI: 10.1016/j.cancergen.2013.06.005]
-
Cancer Genet2013
, vol.206
, pp. 309-316
-
-
Hutchison, J1
Cohen, Z2
Onyeagucha, BC3
Funk, J4
Nelson, MA.5
-
46
-
-
77951030494
-
Modulation of mismatch repair and genomic stability by miR-155
-
46 [PMID: 20351277]
-
46 Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, Adair B, Vannini I, Fanini F, Bottoni A, Costinean S, Sandhu SK, Nuovo GJ, Alder H, Gafa R, Calore F, Ferracin M, Lanza G, Volinia S, Negrini M, McIlhatton MA, Amadori D, Fishel R, Croce CM. Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci USA2010; 107: 6982-6987 [PMID: 20351277 DOI: 10.1073/pnas.1002472107]
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6982-6987
-
-
Valeri, N1
Gasparini, P2
Fabbri, M3
Braconi, C4
Veronese, A5
Lovat, F6
Adair, B7
Vannini, I8
Fanini, F9
Bottoni, A10
Costinean, S11
Sandhu, SK12
Nuovo, GJ13
Alder, H14
Gafa, R15
Calore, F16
Ferracin, M17
Lanza, G18
Volinia, S19
Negrini, M20
McIlhatton, MA21
Amadori, D22
Fishel, R23
Croce, CM.24
more..
-
47
-
-
80053528523
-
Colorectal cancers with microsatellite instability display unique miRNA profles
-
47 [PMID: 21844009]
-
47 Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, Cuatrecasas M, Arnold M, Meltzer SJ, Syngal S, Stoffel E, Jover R, Llor X, Castells A, Boland CR, Gironella M, Goel A. Colorectal cancers with microsatellite instability display unique miRNA profles. Clin Cancer Res2011; 17: 6239-6249 [PMID: 21844009 DOI: 10.1158/1078-0432.CCR-11-1424]
-
Clin Cancer Res2011
, vol.17
, pp. 6239-6249
-
-
Balaguer, F1
Moreira, L2
Lozano, JJ3
Link, A4
Ramirez, G5
Shen, Y6
Cuatrecasas, M7
Arnold, M8
Meltzer, SJ9
Syngal, S10
Stoffel, E11
Jover, R12
Llor, X13
Castells, A14
Boland, CR15
Gironella, M16
Goel, A.17
-
48
-
-
77954368612
-
Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma
-
48 [PMID: 20413677]
-
48 Earle JS, Luthra R, Romans A, Abraham R, Ensor J, Yao H, Hamilton SR. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J Mol Diagn2010; 12: 433-440 [PMID: 20413677 DOI: 10.2353/jmoldx.2010.090154]
-
J Mol Diagn2010
, vol.12
, pp. 433-440
-
-
Earle, JS1
Luthra, R2
Romans, A3
Abraham, R4
Ensor, J5
Yao, H6
Hamilton, SR.7
-
49
-
-
84927154459
-
Identification of subgroup-specific miRNA patterns by epigenetic profling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma
-
49 [PMID: 25767621]
-
49 Kaur S, Lotsari JE, Al-Sohaily S, Warusavitarne J, Kohonen-Corish MR, Peltomäki P. Identification of subgroup-specific miRNA patterns by epigenetic profling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma. Clin Epigenetics2015; 7: 20 [PMID: 25767621 DOI: 10.1186/s13148-015-0059-3]
-
Clin Epigenetics2015
, vol.7
, pp. 20
-
-
Kaur, S1
Lotsari, JE2
Al-Sohaily, S3
Warusavitarne, J4
Kohonen-Corish, MR5
Peltomäki, P.6
-
50
-
-
56549129538
-
Chromatin structure analyses identify miRNA promoters
-
50 [PMID: 19056895]
-
50 Ozsolak F, Poling LL, Wang Z, Liu H, Liu XS, Roeder RG, Zhang X, Song JS, Fisher DE. Chromatin structure analyses identify miRNA promoters. Genes Dev2008; 22: 3172-3183 [PMID: 19056895 DOI: 10.1101/gad.1706508]
-
Genes Dev2008
, vol.22
, pp. 3172-3183
-
-
Ozsolak, F1
Poling, LL2
Wang, Z3
Liu, H4
Liu, XS5
Roeder, RG6
Zhang, X7
Song, JS8
Fisher, DE.9
-
51
-
-
20244386256
-
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X
-
51 [PMID: 15855431]
-
51 Lindor NM, Rabe K, Petersen GM, Haile R, Casey G, Baron J, Gallinger S, Bapat B, Aronson M, Hopper J, Jass J, LeMarchand L, Grove J, Potter J, Newcomb P, Terdiman JP, Conrad P, Moslein G, Goldberg R, Ziogas A, Anton-Culver H, de Andrade M, Siegmund K, Thibodeau SN, Boardman LA, Seminara D. Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. JAMA2005; 293: 1979-1985 [PMID: 15855431]
-
(2005)
JAMA
, vol.293
, pp. 1979-1985
-
-
Lindor, NM1
Rabe, K2
Petersen, GM3
Haile, R4
Casey, G5
Baron, J6
Gallinger, S7
Bapat, B8
Aronson, M9
Hopper, J10
Jass, J11
LeMarchand, L12
Grove, J13
Potter, J14
Newcomb, P15
Terdiman, JP16
Conrad, P17
Moslein, G18
Goldberg, R19
Ziogas, A20
Anton-Culver, H21
de Andrade, M22
Siegmund, K23
Thibodeau, SN24
Boardman, LA25
Seminara, D.26
more..
-
52
-
-
84858698973
-
Hereditary colorectal cancer diagnostics: morphological features of familial colorectal cancer type X versus Lynch syndrome
-
52 [PMID: 22287689]
-
52 Klarskov L, Holck S, Bernstein I, Nilbert M. Hereditary colorectal cancer diagnostics: morphological features of familial colorectal cancer type X versus Lynch syndrome. J Clin Pathol2012; 65: 352-356 [PMID: 22287689 DOI: 10.1136/jclinpath-2011-200535]
-
J Clin Pathol2012
, vol.65
, pp. 352-356
-
-
Klarskov, L1
Holck, S2
Bernstein, I3
Nilbert, M.4
-
53
-
-
84930757295
-
Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X
-
53 [PMID: 25381643]
-
53 Sánchez-Tomé E, Rivera B, Perea J, Pita G, Rueda D, Mercadillo F, Canal A, Gonzalez-Neira A, Benitez J, Urioste M. Genome-wide linkage analysis and tumoral characterization reveal heterogeneity in familial colorectal cancer type X. J Gastroenterol2015; 50: 657-666 [PMID: 25381643 DOI: 10.1007/s00535-014-1009-0]
-
J Gastroenterol2015
, vol.50
, pp. 657-666
-
-
Sánchez-Tomé, E1
Rivera, B2
Perea, J3
Pita, G4
Rueda, D5
Mercadillo, F6
Canal, A7
Gonzalez-Neira, A8
Benitez, J9
Urioste, M.10
-
54
-
-
85047698408
-
Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization
-
54 [PMID: 12082642]
-
54 Dunican DS, McWilliam P, Tighe O, Parle-McDermott A, Croke DT. Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization. Oncogene2002; 21: 3253-3257 [PMID: 12082642]
-
Oncogene2002
, vol.21
, pp. 3253-3257
-
-
Dunican, DS1
McWilliam, P2
Tighe, O3
Parle-McDermott, A4
Croke, DT.5
-
55
-
-
1442308342
-
Gene expression profling of colon cancer by DNA microarrays and correlation with histoclinical parameters
-
55 [PMID: 14973550]
-
55 Bertucci F, Salas S, Eysteries S, Nasser V, Finetti P, Ginestier C, Charafe-Jauffret E, Loriod B, Bachelart L, Montfort J, Victorero G, Viret F, Ollendorff V, Fert V, Giovaninni M, Delpero JR, Nguyen C, Viens P, Monges G, Birnbaum D, Houlgatte R. Gene expression profling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene2004; 23: 1377-1391 [PMID: 14973550]
-
Oncogene2004
, vol.23
, pp. 1377-1391
-
-
Bertucci, F1
Salas, S2
Eysteries, S3
Nasser, V4
Finetti, P5
Ginestier, C6
Charafe-Jauffret, E7
Loriod, B8
Bachelart, L9
Montfort, J10
Victorero, G11
Viret, F12
Ollendorff, V13
Fert, V14
Giovaninni, M15
Delpero, JR16
Nguyen, C17
Viens, P18
Monges, G19
Birnbaum, D20
Houlgatte, R.21
more..
-
56
-
-
84855696555
-
Familial colorectal cancer type X syndrome: two distinct molecular entities?
-
56 [PMID: 21837511]
-
56 Francisco I, Albuquerque C, Lage P, Belo H, Vitoriano I, Filipe B, Claro I, Ferreira S, Rodrigues P, Chaves P, Leitão CN, Pereira AD. Familial colorectal cancer type X syndrome: two distinct molecular entities? Fam Cancer2011; 10: 623-631 [PMID: 21837511 DOI: 10.1007/s10689-011-9473-7]
-
Fam Cancer2011
, vol.10
, pp. 623-631
-
-
Francisco, I1
Albuquerque, C2
Lage, P3
Belo, H4
Vitoriano, I5
Filipe, B6
Claro, I7
Ferreira, S8
Rodrigues, P9
Chaves, P10
Leitão, CN11
Pereira, AD.12
-
57
-
-
84875731688
-
Gain of chromosomal region 20q and loss of 18 discriminates between Lynch syndrome and familial colorectal cancer
-
57 [PMID: 23245329]
-
57 Therkildsen C, Jönsson G, Dominguez-Valentin M, Nissen A, Rambech E, Halvarsson B, Bernstein I, Borg K, Nilbert M. Gain of chromosomal region 20q and loss of 18 discriminates between Lynch syndrome and familial colorectal cancer. Eur J Cancer2013; 49: 1226-1235 [PMID: 23245329 DOI: 10.1016/j.ejca.2012.11.011]
-
Eur J Cancer2013
, vol.49
, pp. 1226-1235
-
-
Therkildsen, C1
Jönsson, G2
Dominguez-Valentin, M3
Nissen, A4
Rambech, E5
Halvarsson, B6
Bernstein, I7
Borg, K8
Nilbert, M.9
-
58
-
-
84881540394
-
Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x
-
58 [PMID: 23951239]
-
58 Dominguez-Valentin M, Therkildsen C, Veerla S, Jönsson M, Bernstein I, Borg A, Nilbert M. Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x. PLoS One2013; 8: e71755 [PMID: 23951239 DOI: 10.1371/journal. pone.0071755]
-
PLoS One2013
, vol.8
, pp. e71755
-
-
Dominguez-Valentin, M1
Therkildsen, C2
Veerla, S3
Jönsson, M4
Bernstein, I5
Borg, A6
Nilbert, M.7
-
59
-
-
0032698210
-
Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis
-
59 [PMID: 10537280]
-
59 Watanabe K, Kawamori T, Nakatsugi S, Ohta T, Ohuchida S, Yamamoto H, Maruyama T, Kondo K, Ushikubi F, Narumiya S, Sugimura T, Wakabayashi K. Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis. Cancer Res1999; 59: 5093-5096 [PMID: 10537280]
-
Cancer Res1999
, vol.59
, pp. 5093-5096
-
-
Watanabe, K1
Kawamori, T2
Nakatsugi, S3
Ohta, T4
Ohuchida, S5
Yamamoto, H6
Maruyama, T7
Kondo, K8
Ushikubi, F9
Narumiya, S10
Sugimura, T11
Wakabayashi, K.12
-
60
-
-
81155154267
-
ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression
-
60 [PMID: 21937683]
-
60 Kim SH, Park YY, Kim SW, Lee JS, Wang D, DuBois RN. ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression. Cancer Res2011; 71: 7010-7020 [PMID: 21937683 DOI: 10.1158/0008-5472. CAN-11-1262]
-
Cancer Res2011
, vol.71
, pp. 7010-7020
-
-
Kim, SH1
Park, YY2
Kim, SW3
Lee, JS4
Wang, D5
DuBois, RN.6
-
61
-
-
84923116889
-
Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X
-
61 [PMID: 25307848]
-
61 Schulz E, Klampf P, Holzapfel S, Janecke AR, Ulz P, Renner W, Kashofer K, Nojima S, Leitner A, Zebisch A, Wölfer A, Hofer S, Gerger A, Lax S, Beham-Schmid C, Steinke V, Heitzer E, Geigl JB, Windpassinger C, Hoefler G, Speicher MR, Boland CR, Kumanogoh A, Sill H. Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X. Nat Commun2014; 5: 5191 [PMID: 25307848 DOI: 10.1038/ncomms6191]
-
Nat Commun2014
, vol.5
, pp. 5191
-
-
Schulz, E1
Klampf, P2
Holzapfel, S3
Janecke, AR4
Ulz, P5
Renner, W6
Kashofer, K7
Nojima, S8
Leitner, A9
Zebisch, A10
Wölfer, A11
Hofer, S12
Gerger, A13
Lax, S14
Beham-Schmid, C15
Steinke, V16
Heitzer, E17
Geigl, JB18
Windpassinger, C19
Hoefler, G20
Speicher, MR21
Boland, CR22
Kumanogoh, A23
Sill, H.24
more..
-
62
-
-
84855678488
-
A survey of APC mutations in Quebec
-
62 [PMID: 21779980]
-
62 Jarry J, Brunet JS, Laframboise R, Drouin R, Latreille J, Richard C, Gekas J, Maranda B, Monczak Y, Wong N, Pouchet C, Zaor S, Kasprzak L, Palma L, Wu MK, Tischkowitz M, Foulkes WD, Chong G. A survey of APC mutations in Quebec. Fam Cancer2011; 10: 659-665 [PMID: 21779980 DOI: 10.1007/s10689-011-9468-4]
-
Fam Cancer2011
, vol.10
, pp. 659-665
-
-
Jarry, J1
Brunet, JS2
Laframboise, R3
Drouin, R4
Latreille, J5
Richard, C6
Gekas, J7
Maranda, B8
Monczak, Y9
Wong, N10
Pouchet, C11
Zaor, S12
Kasprzak, L13
Palma, L14
Wu, MK15
Tischkowitz, M16
Foulkes, WD17
Chong, G.18
-
63
-
-
0025817880
-
Identifcation of FAP locus genes from chromosome 5q21
-
63 [PMID: 1651562]
-
63 Kinzler KW, Nilbert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D. Identifcation of FAP locus genes from chromosome 5q21. Science1991; 253: 661-665 [PMID: 1651562]
-
Science1991
, vol.253
, pp. 661-665
-
-
Kinzler, KW1
Nilbert, MC2
Su, LK3
Vogelstein, B4
Bryan, TM5
Levy, DB6
Smith, KJ7
Preisinger, AC8
Hedge, P9
McKechnie, D.10
-
64
-
-
0037162282
-
Casein kinase 1: a Wnt’er of disconnect
-
64 [PMID: 12176352]
-
64 Polakis P. Casein kinase 1: a Wnt’er of disconnect. Curr Biol2002; 12: R499-R501 [PMID: 12176352]
-
Curr Biol2002
, vol.12
, pp. R499-R501
-
-
Polakis, P.1
-
65
-
-
0035070046
-
Mutations in the APC tumour suppressor gene cause chromosomal instability
-
65 [PMID: 11283620]
-
65 Fodde R, Kuipers J, Rosenberg C, Smits R, Kielman M, Gaspar C, van Es JH, Breukel C, Wiegant J, Giles RH, Clevers H. Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat Cell Biol2001; 3: 433-438 [PMID: 11283620]
-
Nat Cell Biol2001
, vol.3
, pp. 433-438
-
-
Fodde, R1
Kuipers, J2
Rosenberg, C3
Smits, R4
Kielman, M5
Gaspar, C6
van Es, JH7
Breukel, C8
Wiegant, J9
Giles, RH10
Clevers, H.11
-
66
-
-
0035067391
-
A role for the Adenomatous Polyposis Coli protein in chromosome segregation
-
66 [PMID: 11283619]
-
66 Kaplan KB, Burds AA, Swedlow JR, Bekir SS, Sorger PK, Näthke IS. A role for the Adenomatous Polyposis Coli protein in chromosome segregation. Nat Cell Biol2001; 3: 429-432 [PMID: 11283619]
-
Nat Cell Biol2001
, vol.3
, pp. 429-432
-
-
Kaplan, KB1
Burds, AA2
Swedlow, JR3
Bekir, SS4
Sorger, PK5
Näthke, IS.6
-
67
-
-
33749006194
-
Familial adenomatous polyposis: The practical applications of clinical and molecular screening
-
67 [PMID: 16998668]
-
67 Rozen P, Macrae F. Familial adenomatous polyposis: The practical applications of clinical and molecular screening. Fam Cancer2006; 5: 227-235 [PMID: 16998668]
-
Fam Cancer2006
, vol.5
, pp. 227-235
-
-
Rozen, P1
Macrae, F.2
-
68
-
-
84995780101
-
The evolution of colorectal cancer genetics-Part 2: clinical implications and applications
-
68 [PMID: 25276406]
-
68 Schlussel AT, Gagliano RA, Seto-Donlon S, Eggerding F, Donlon T, Berenberg J, Lynch HT. The evolution of colorectal cancer genetics-Part 2: clinical implications and applications. J Gastrointest Oncol2014; 5: 336-344 [PMID: 25276406 DOI: 10.3978/j.issn.2078-6891.2014.068]
-
J Gastrointest Oncol2014
, vol.5
, pp. 336-344
-
-
Schlussel, AT1
Gagliano, RA2
Seto-Donlon, S3
Eggerding, F4
Donlon, T5
Berenberg, J6
Lynch, HT.7
-
69
-
-
0029928160
-
APC gene: database of germline and somatic mutations in human tumors and cell lines
-
69 [PMID: 8594558]
-
69 Béroud C, Soussi T. APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res1996; 24: 121-124 [PMID: 8594558]
-
Nucleic Acids Res1996
, vol.24
, pp. 121-124
-
-
Béroud, C1
Soussi, T.2
-
70
-
-
78751687554
-
Gene variants associated to malignant thyroid disease in familial adenomatous polyposis: a novel APC germline mutation
-
70 [PMID: 20935450]
-
70 Martayan A, Sanchez-Mete L, Baldelli R, Falvo E, Barnabei A, Conti L, Giacomini P, Appetecchia M, Stigliano V. Gene variants associated to malignant thyroid disease in familial adenomatous polyposis: a novel APC germline mutation. J Endocrinol Invest2010; 33: 603-606 [PMID: 20935450 DOI: 10.3275/7289]
-
J Endocrinol Invest2010
, vol.33
, pp. 603-606
-
-
Martayan, A1
Sanchez-Mete, L2
Baldelli, R3
Falvo, E4
Barnabei, A5
Conti, L6
Giacomini, P7
Appetecchia, M8
Stigliano, V.9
-
71
-
-
0028970197
-
The molecular basis of Turcot’s syndrome
-
71 [PMID: 7661930]
-
71 Hamilton SR, Liu B, Parsons RE, Papadopoulos N, Jen J, Powell SM, Krush AJ, Berk T, Cohen Z, Tetu B. The molecular basis of Turcot’s syndrome. N Engl J Med1995; 332: 839-847 [PMID: 7661930]
-
N Engl J Med1995
, vol.332
, pp. 839-847
-
-
Hamilton, SR1
Liu, B2
Parsons, RE3
Papadopoulos, N4
Jen, J5
Powell, SM6
Krush, AJ7
Berk, T8
Cohen, Z9
Tetu, B.10
-
72
-
-
50049124155
-
Extra-intestinal manifestations of familial adenomatous polyposis
-
72 [PMID: 18612695]
-
72 Groen EJ, Roos A, Muntinghe FL, Enting RH, de Vries J, Kleibeuker JH, Witjes MJ, Links TP, van Beek AP. Extra-intestinal manifestations of familial adenomatous polyposis. Ann Surg Oncol2008; 15: 2439-2450 [PMID: 18612695 DOI: 10.1245/s10434-008-9981-3]
-
Ann Surg Oncol2008
, vol.15
, pp. 2439-2450
-
-
Groen, EJ1
Roos, A2
Muntinghe, FL3
Enting, RH4
de Vries, J5
Kleibeuker, JH6
Witjes, MJ7
Links, TP8
van Beek, AP.9
-
73
-
-
84884944959
-
Thyroid cancer complicating familial adenomatous polyposis: mutation spectrum of at-risk individuals
-
73 [PMID: 24093640]
-
73 Septer S, Slowik V, Morgan R, Dai H, Attard T. Thyroid cancer complicating familial adenomatous polyposis: mutation spectrum of at-risk individuals. Hered Cancer Clin Pract2013; 11: 13 [PMID: 24093640 DOI: 10.1186/1897-4287-11-13]
-
Hered Cancer Clin Pract2013
, vol.11
, pp. 13
-
-
Septer, S1
Slowik, V2
Morgan, R3
Dai, H4
Attard, T.5
-
74
-
-
0036157818
-
Arylamine N-acetyltransferase type 2 and glutathione S-transferases M1 and T1 polymorphisms in familial adenomatous polyposis
-
74 [PMID: 11773864]
-
74 Lamberti C, Jungck M, Laarmann M, Knapp M, Caspari R, Friedl W, Sauerbruch T, Propping P, Kruse R. Arylamine N-acetyltransferase type 2 and glutathione S-transferases M1 and T1 polymorphisms in familial adenomatous polyposis. Pharmacogenetics2002; 12: 49-54 [PMID: 11773864]
-
Pharmacogenetics2002
, vol.12
, pp. 49-54
-
-
Lamberti, C1
Jungck, M2
Laarmann, M3
Knapp, M4
Caspari, R5
Friedl, W6
Sauerbruch, T7
Propping, P8
Kruse, R.9
-
75
-
-
84943361038
-
Familial adenomatous polyposis-associated and sporadic pyloric gland adenomas of the upper gastrointestinal tract share common genetic features
-
75 [PMID: 25832318]
-
75 Hashimoto T, Ogawa R, Matsubara A, Taniguchi H, Sugano K, Ushiama M, Yoshida T, Kanai Y, Sekine S. Familial adenomatous polyposis-associated and sporadic pyloric gland adenomas of the upper gastrointestinal tract share common genetic features. Histopathology2015; 67: 689-698 [PMID: 25832318 DOI: 10.1111/his.12705]
-
Histopathology2015
, vol.67
, pp. 689-698
-
-
Hashimoto, T1
Ogawa, R2
Matsubara, A3
Taniguchi, H4
Sugano, K5
Ushiama, M6
Yoshida, T7
Kanai, Y8
Sekine, S.9
-
76
-
-
33749320834
-
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression
-
76 [PMID: 17030180]
-
76 Janssen KP, Alberici P, Fsihi H, Gaspar C, Breukel C, Franken P, Rosty C, Abal M, El Marjou F, Smits R, Louvard D, Fodde R, Robine S. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression. Gastroenterology2006; 131: 1096-1109 [PMID: 17030180]
-
Gastroenterology2006
, vol.131
, pp. 1096-1109
-
-
Janssen, KP1
Alberici, P2
Fsihi, H3
Gaspar, C4
Breukel, C5
Franken, P6
Rosty, C7
Abal, M8
El Marjou, F9
Smits, R10
Louvard, D11
Fodde, R12
Robine, S.13
-
77
-
-
42649125571
-
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
-
77 [PMID: 18372904]
-
77 Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon. Nat Genet2008; 40: 600-608 [PMID: 18372904 DOI: 10.1038/ng.115]
-
Nat Genet2008
, vol.40
, pp. 600-608
-
-
Haigis, KM1
Kendall, KR2
Wang, Y3
Cheung, A4
Haigis, MC5
Glickman, JN6
Niwa-Kawakita, M7
Sweet-Cordero, A8
Sebolt-Leopold, J9
Shannon, KM10
Settleman, J11
Giovannini, M12
Jacks, T.13
-
78
-
-
65549159598
-
A two-step model for colon adenoma initiation and progression caused by APC loss
-
78 [PMID: 19450512]
-
78 Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, Broadbent T, Sarkar S, Burt RW, Jones DA. A two-step model for colon adenoma initiation and progression caused by APC loss. Cell2009; 137: 623-634 [PMID: 19450512 DOI: 10.1016/j.cell.2009.02.037]
-
Cell2009
, vol.137
, pp. 623-634
-
-
Phelps, RA1
Chidester, S2
Dehghanizadeh, S3
Phelps, J4
Sandoval, IT5
Rai, K6
Broadbent, T7
Sarkar, S8
Burt, RW9
Jones, DA.10
-
79
-
-
77951008504
-
Onco-genic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas
-
79 [PMID: 20196079]
-
79 Obrador-Hevia A, Chin SF, González S, Rees J, Vilardell F, Greenson JK, Cordero D, Moreno V, Caldas C, Capellá G. Onco-genic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas. J Pathol2010; 221: 57-67 [PMID: 20196079 DOI: 10.1002/path.2685]
-
J Pathol2010
, vol.221
, pp. 57-67
-
-
Obrador-Hevia, A1
Chin, SF2
González, S3
Rees, J4
Vilardell, F5
Greenson, JK6
Cordero, D7
Moreno, V8
Caldas, C9
Capellá, G.10
-
80
-
-
39649123486
-
Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families
-
80 [PMID: 18027849]
-
80 Romero-Giménez J, Dopeso H, Blanco I, Guerra-Moreno A, Gonzalez S, Vogt S, Aretz S, Schwartz S, Capella G, Arango D. Germline hypermethylation of the APC promoter is not a frequent cause of familial adenomatous polyposis in APC/MUTYH mutation negative families. Int J Cancer2008; 122: 1422-1425 [PMID: 18027849]
-
Int J Cancer2008
, vol.122
, pp. 1422-1425
-
-
Romero-Giménez, J1
Dopeso, H2
Blanco, I3
Guerra-Moreno, A4
Gonzalez, S5
Vogt, S6
Aretz, S7
Schwartz, S8
Capella, G9
Arango, D.10
-
81
-
-
49349088305
-
Somatic APC inactivation mechanisms in sporadic colorectal cancer cases in Hungary
-
81 [PMID: 18369740]
-
81 Kámory E, Olasz J, Csuka O. Somatic APC inactivation mechanisms in sporadic colorectal cancer cases in Hungary. Pathol Oncol Res2008; 14: 51-56 [PMID: 18369740 DOI: 10.1007/s1225 3-008-9019-y]
-
Pathol Oncol Res2008
, vol.14
, pp. 51-56
-
-
Kámory, E1
Olasz, J2
Csuka, O.3
-
82
-
-
50249105303
-
Promoter hypermethylation and loss of heterozygosity of the APC gene in patients with familial adenomatous polyposis
-
82 [PMID: 18683131]
-
82 Zhang YY, Chen SQ, Zhu M, Li JT, Ma GJ, Zhang XM, Zhou JN. [Promoter hypermethylation and loss of heterozygosity of the APC gene in patients with familial adenomatous polyposis]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi2008; 25: 378-381 [PMID: 18683131]
-
Zhonghua Yi Xue Yi Chuan Xue Za Zhi2008
, vol.25
, pp. 378-381
-
-
Zhang, YY1
Chen, SQ2
Zhu, M3
Li, JT4
Ma, GJ5
Zhang, XM6
Zhou, JN.7
-
83
-
-
56549109267
-
Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations
-
83 [PMID: 18977219]
-
83 Segditsas S, Sieber OM, Rowan A, Setien F, Neale K, Phillips RK, Ward R, Esteller M, Tomlinson IP. Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations. Exp Mol Pathol2008; 85: 201-206 [PMID: 18977219 DOI: 10.1016/j.yexmp.2008.09.006]
-
Exp Mol Pathol2008
, vol.85
, pp. 201-206
-
-
Segditsas, S1
Sieber, OM2
Rowan, A3
Setien, F4
Neale, K5
Phillips, RK6
Ward, R7
Esteller, M8
Tomlinson, IP.9
-
84
-
-
84905754618
-
Promoter-specifc alterations of APC are a rare cause for mutation-negative familial adenomatous polyposis
-
84 [PMID: 24946964]
-
84 Pavicic W, Nieminen TT, Gylling A, Pursiheimo JP, Laiho A, Gyenesei A, Järvinen HJ, Peltomäki P. Promoter-specifc alterations of APC are a rare cause for mutation-negative familial adenomatous polyposis. Genes Chromosomes Cancer2014; 53: 857-864 [PMID: 24946964 DOI: 10.1002/gcc.22197]
-
Genes Chromosomes Cancer2014
, vol.53
, pp. 857-864
-
-
Pavicic, W1
Nieminen, TT2
Gylling, A3
Pursiheimo, JP4
Laiho, A5
Gyenesei, A6
Järvinen, HJ7
Peltomäki, P.8
-
85
-
-
36248932653
-
Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas
-
85 [PMID: 17873900]
-
85 Berkhout M, Nagtegaal ID, Cornelissen SJ, Dekkers MM, van de Molengraft FJ, Peters WH, Nagengast FM, van Krieken JH, Jeuken JW. Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas. Mod Pathol2007; 20: 1253-1262 [PMID: 17873900]
-
Mod Pathol2007
, vol.20
, pp. 1253-1262
-
-
Berkhout, M1
Nagtegaal, ID2
Cornelissen, SJ3
Dekkers, MM4
van de Molengraft, FJ5
Peters, WH6
Nagengast, FM7
van Krieken, JH8
Jeuken, JW.9
-
86
-
-
31544481421
-
DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients
-
86 [PMID: 16152625]
-
86 Wynter CV, Kambara T, Walsh MD, Leggett BA, Young J, Jass JR. DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients. Int J Cancer2006; 118: 907-915 [PMID: 16152625]
-
Int J Cancer2006
, vol.118
, pp. 907-915
-
-
Wynter, CV1
Kambara, T2
Walsh, MD3
Leggett, BA4
Young, J5
Jass, JR.6
-
87
-
-
84884595808
-
Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors
-
87 [PMID: 23397547]
-
87 Kamatani A, Nakagawa Y, Akao Y, Maruyama N, Nagasaka M, Shibata T, Tahara T, Hirata I. Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors. Med Mol Morphol2013; 46: 166-171 [PMID: 23397547 DOI: 10.1007/s00795-013-0020-5]
-
Med Mol Morphol2013
, vol.46
, pp. 166-171
-
-
Kamatani, A1
Nakagawa, Y2
Akao, Y3
Maruyama, N4
Nagasaka, M5
Shibata, T6
Tahara, T7
Hirata, I.8
-
88
-
-
84906896673
-
Underexpression of miR-126 and miR-20b in hereditary and nonhereditary colorectal tumors
-
88 [PMID: 24994098]
-
88 Yamaguchi T, Iijima T, Wakaume R, Takahashi K, Matsumoto H, Nakano D, Nakayama Y, Mori T, Horiguchi S, Miyaki M. Underexpression of miR-126 and miR-20b in hereditary and nonhereditary colorectal tumors. Oncology2014; 87: 58-66 [PMID: 24994098 DOI: 10.1159/000363303]
-
Oncology2014
, vol.87
, pp. 58-66
-
-
Yamaguchi, T1
Iijima, T2
Wakaume, R3
Takahashi, K4
Matsumoto, H5
Nakano, D6
Nakayama, Y7
Mori, T8
Horiguchi, S9
Miyaki, M.10
-
89
-
-
7944225535
-
Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk
-
89 [PMID: 15523092]
-
89 Croitoru ME, Cleary SP, Di Nicola N, Manno M, Selander T, Aronson M, Redston M, Cotterchio M, Knight J, Gryfe R, Gallinger S. Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. J Natl Cancer Inst2004; 96: 1631-1634 [PMID: 15523092]
-
J Natl Cancer Inst2004
, vol.96
, pp. 1631-1634
-
-
Croitoru, ME1
Cleary, SP2
Di Nicola, N3
Manno, M4
Selander, T5
Aronson, M6
Redston, M7
Cotterchio, M8
Knight, J9
Gryfe, R10
Gallinger, S.11
-
90
-
-
69849112388
-
Clinical implications of the colorectal cancer risk associated with MUTYH mutation
-
90 [PMID: 19620482]
-
90 Lubbe SJ, Di Bernardo MC, Chandler IP, Houlston RS. Clinical implications of the colorectal cancer risk associated with MUTYH mutation. J Clin Oncol2009; 27: 3975-3980 [PMID: 19620482 DOI: 10.1200/JCO.2008.21.6853]
-
J Clin Oncol2009
, vol.27
, pp. 3975-3980
-
-
Lubbe, SJ1
Di Bernardo, MC2
Chandler, IP3
Houlston, RS.4
-
91
-
-
84859755754
-
Understanding MYH-associated neoplasia
-
91 [PMID: 22469805]
-
91 Church J, Heald B, Burke C, Kalady M. Understanding MYH-associated neoplasia. Dis Colon Rectum2012; 55: 359-362 [PMID: 22469805 DOI: 10.1097/DCR.0b013e31823a9392]
-
Dis Colon Rectum2012
, vol.55
, pp. 359-362
-
-
Church, J1
Heald, B2
Burke, C3
Kalady, M.4
-
92
-
-
84896542406
-
MUTYH-associated colorectal cancer and adenomatous polyposis
-
92 [PMID: 23605219]
-
92 Yamaguchi S, Ogata H, Katsumata D, Nakajima M, Fujii T, Tsutsumi S, Asao T, Sasaki K, Kuwano H, Kato H. MUTYH-associated colorectal cancer and adenomatous polyposis. Surg Today2014; 44: 593-600 [PMID: 23605219 DOI: 10.1007/s00595-013-0592-7]
-
Surg Today2014
, vol.44
, pp. 593-600
-
-
Yamaguchi, S1
Ogata, H2
Katsumata, D3
Nakajima, M4
Fujii, T5
Tsutsumi, S6
Asao, T7
Sasaki, K8
Kuwano, H9
Kato, H.10
-
93
-
-
20544452084
-
Germline susceptibility to colorectal cancer due to base-excision repair gene defects
-
93 [PMID: 15931596]
-
93 Farrington SM, Tenesa A, Barnetson R, Wiltshire A, Prendergast J, Porteous M, Campbell H, Dunlop MG. Germline susceptibility to colorectal cancer due to base-excision repair gene defects. Am J Hum Genet2005; 77: 112-119 [PMID: 15931596]
-
Am J Hum Genet2005
, vol.77
, pp. 112-119
-
-
Farrington, SM1
Tenesa, A2
Barnetson, R3
Wiltshire, A4
Prendergast, J5
Porteous, M6
Campbell, H7
Dunlop, MG.8
-
94
-
-
0036478899
-
Inherited variants of MYH associated with somatic G: C–> T: A mutations in colorectal tumors
-
94 [PMID: 11818965]
-
94 Al-Tassan N, Chmiel NH, Maynard J, Fleming N, Livingston AL, Williams GT, Hodges AK, Davies DR, David SS, Sampson JR, Cheadle JP. Inherited variants of MYH associated with somatic G: C–> T: A mutations in colorectal tumors. Nat Genet2002; 30: 227-232 [PMID: 11818965]
-
Nat Genet2002
, vol.30
, pp. 227-232
-
-
Al-Tassan, N1
Chmiel, NH2
Maynard, J3
Fleming, N4
Livingston, AL5
Williams, GT6
Hodges, AK7
Davies, DR8
David, SS9
Sampson, JR10
Cheadle, JP.11
-
95
-
-
0029445186
-
Hereditary cancers: from discovery to intervention
-
95 [PMID: 8573454]
-
95 Knudson AG. Hereditary cancers: from discovery to intervention. J Natl Cancer Inst Monogr1995; (17): 5-7 [PMID: 8573454]
-
J Natl Cancer Inst Monogr1995
, Issue.17
, pp. 5-7
-
-
Knudson, AG.1
-
96
-
-
85099905781
-
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G: C–> T: A mutations
-
96 [PMID: 12393807]
-
96 Jones S, Emmerson P, Maynard J, Best JM, Jordan S, Williams GT, Sampson JR, Cheadle JP. Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G: C–> T: A mutations. Hum Mol Genet2002; 11: 2961-2967 [PMID: 12393807]
-
Hum Mol Genet2002
, vol.11
, pp. 2961-2967
-
-
Jones, S1
Emmerson, P2
Maynard, J3
Best, JM4
Jordan, S5
Williams, GT6
Sampson, JR7
Cheadle, JP.8
-
97
-
-
0037468517
-
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
-
97 [PMID: 12606733]
-
97 Sieber OM, Lipton L, Crabtree M, Heinimann K, Fidalgo P, Phillips RK, Bisgaard ML, Orntoft TF, Aaltonen LA, Hodgson SV, Thomas HJ, Tomlinson IP. Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med2003; 348: 791-799 [PMID: 12606733]
-
N Engl J Med2003
, vol.348
, pp. 791-799
-
-
Sieber, OM1
Lipton, L2
Crabtree, M3
Heinimann, K4
Fidalgo, P5
Phillips, RK6
Bisgaard, ML7
Orntoft, TF8
Aaltonen, LA9
Hodgson, SV10
Thomas, HJ11
Tomlinson, IP.12
-
98
-
-
58649111511
-
Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis
-
98 [PMID: 19032956]
-
98 Nielsen M, Joerink-van de Beld MC, Jones N, Vogt S, Tops CM, Vasen HF, Sampson JR, Aretz S, Hes FJ. Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. Gastroenterology2009; 136: 471-476 [PMID: 19032956 DOI: 10.1053/j.gastro.2008.10.056]
-
Gastroenterology2009
, vol.136
, pp. 471-476
-
-
Nielsen, M1
Joerink-van de Beld, MC2
Jones, N3
Vogt, S4
Tops, CM5
Vasen, HF6
Sampson, JR7
Aretz, S8
Hes, FJ.9
-
99
-
-
25844529526
-
Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas
-
99 [PMID: 15890374]
-
99 Miyaki M, Iijima T, Yamaguchi T, Hishima T, Tamura K, Utsunomiya J, Mori T. Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas. Mutat Res2005; 578: 430-433 [PMID: 15890374]
-
Mutat Res2005
, vol.578
, pp. 430-433
-
-
Miyaki, M1
Iijima, T2
Yamaguchi, T3
Hishima, T4
Tamura, K5
Utsunomiya, J6
Mori, T.7
-
100
-
-
33745065564
-
A novel functionally defcient MYH variant in individuals with colorectal adenomatous polyposis
-
100 [PMID: 16134146]
-
100 Alhopuro P, Parker AR, Lehtonen R, Enholm S, Järvinen HJ, Mecklin JP, Karhu A, Eshleman JR, Aaltonen LA. A novel functionally defcient MYH variant in individuals with colorectal adenomatous polyposis. Hum Mutat2005; 26: 393 [PMID: 16134146]
-
Hum Mutat2005
, vol.26
, pp. 393
-
-
Alhopuro, P1
Parker, AR2
Lehtonen, R3
Enholm, S4
Järvinen, HJ5
Mecklin, JP6
Karhu, A7
Eshleman, JR8
Aaltonen, LA.9
-
101
-
-
84872859784
-
MUTYH c.933+3A& gt; C, associated with a severely impaired gene expression, is the first Italian founder mutation in MUTYH-Associated Polyposis
-
101 [PMID: 22865608]
-
101 Pin E, Pastrello C, Tricarico R, Papi L, Quaia M, Fornasarig M, Carnevali I, Oliani C, Fornasin A, Agostini M, Maestro R, Barana D, Aretz S, Genuardi M, Viel A. MUTYH c.933+3A& gt; C, associated with a severely impaired gene expression, is the first Italian founder mutation in MUTYH-Associated Polyposis. Int J Cancer2013; 132: 1060-1069 [PMID: 22865608 DOI: 10.1002/ijc.27761]
-
Int J Cancer2013
, vol.132
, pp. 1060-1069
-
-
Pin, E1
Pastrello, C2
Tricarico, R3
Papi, L4
Quaia, M5
Fornasarig, M6
Carnevali, I7
Oliani, C8
Fornasin, A9
Agostini, M10
Maestro, R11
Barana, D12
Aretz, S13
Genuardi, M14
Viel, A.15
-
102
-
-
84885019031
-
Oxidative DNA damage drives carcinogenesis in MUTYH-associated-polyposis by specific mutations of mitochondrial and MAPK genes
-
102 [PMID: 23599153]
-
102 Venesio T, Balsamo A, Errichiello E, Ranzani GN, Risio M. Oxidative DNA damage drives carcinogenesis in MUTYH-associated-polyposis by specific mutations of mitochondrial and MAPK genes. Mod Pathol2013; 26: 1371-1381 [PMID: 23599153 DOI: 10.1038/modpathol.2013.66]
-
Mod Pathol2013
, vol.26
, pp. 1371-1381
-
-
Venesio, T1
Balsamo, A2
Errichiello, E3
Ranzani, GN4
Risio, M.5
-
103
-
-
84903575952
-
Juvenile polyposis syndrome
-
103 [PMID: 25097590]
-
103 Cichy W, Klincewicz B, Plawski A. Juvenile polyposis syndrome. Arch Med Sci2014; 10: 570-577 [PMID: 25097590 DOI: 10.5114/aoms.2014.43750]
-
Arch Med Sci2014
, vol.10
, pp. 570-577
-
-
Cichy, W1
Klincewicz, B2
Plawski, A.3
-
104
-
-
12144286738
-
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4)
-
104 [PMID: 15031030]
-
104 Gallione CJ, Repetto GM, Legius E, Rustgi AK, Schelley SL, Tejpar S, Mitchell G, Drouin E, Westermann CJ, Marchuk DA. A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4). Lancet2004; 363: 852-859 [PMID: 15031030]
-
Lancet2004
, vol.363
, pp. 852-859
-
-
Gallione, CJ1
Repetto, GM2
Legius, E3
Rustgi, AK4
Schelley, SL5
Tejpar, S6
Mitchell, G7
Drouin, E8
Westermann, CJ9
Marchuk, DA.10
-
105
-
-
83155165469
-
Juvenile polyposis syndrome
-
105 [PMID: 22171123]
-
105 Brosens LA, Langeveld D, van Hattem WA, Giardiello FM, Offerhaus GJ. Juvenile polyposis syndrome. World J Gastroenterol2011; 17: 4839-4844 [PMID: 22171123 DOI: 10.3748/wjg.v17. i44.4839]
-
World J Gastroenterol2011
, vol.17
, pp. 4839-4844
-
-
Brosens, LA1
Langeveld, D2
van Hattem, WA3
Giardiello, FM4
Offerhaus, GJ.5
-
106
-
-
18344378415
-
Common deletion of SMAD4 in juvenile polyposis is a mutational hotspot
-
106 [PMID: 11920286]
-
106 Howe JR, Shellnut J, Wagner B, Ringold JC, Sayed MG, Ahmed AF, Lynch PM, Amos CI, Sistonen P, Aaltonen LA. Common deletion of SMAD4 in juvenile polyposis is a mutational hotspot. Am J Hum Genet2002; 70: 1357-1362 [PMID: 11920286]
-
Am J Hum Genet2002
, vol.70
, pp. 1357-1362
-
-
Howe, JR1
Shellnut, J2
Wagner, B3
Ringold, JC4
Sayed, MG5
Ahmed, AF6
Lynch, PM7
Amos, CI8
Sistonen, P9
Aaltonen, LA.10
-
107
-
-
84922394840
-
Identifcation of coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome
-
107 [PMID: 25129392]
-
107 Yamaguchi J, Nagayama S, Chino A, Sakata A, Yamamoto N, Sato Y, Ashihara Y, Kita M, Nomura S, Ishikawa Y, Igarashi M, Ueno M, Arai M. Identifcation of coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome. Jpn J Clin Oncol2014; 44: 1004-1008 [PMID: 25129392 DOI: 10.1093/jjco/hyu111]
-
Jpn J Clin Oncol2014
, vol.44
, pp. 1004-1008
-
-
Yamaguchi, J1
Nagayama, S2
Chino, A3
Sakata, A4
Yamamoto, N5
Sato, Y6
Ashihara, Y7
Kita, M8
Nomura, S9
Ishikawa, Y10
Igarashi, M11
Ueno, M12
Arai, M.13
-
108
-
-
0034063711
-
Analysis of genetic and phenotypic heterogeneity in juvenile polyposis
-
108 [PMID: 10764709]
-
108 Woodford-Richens K, Bevan S, Churchman M, Dowling B, Jones D, Norbury CG, Hodgson SV, Desai D, Neale K, Phillips RK, Young J, Leggett B, Dunlop M, Rozen P, Eng C, Markie D, Rodriguez-Bigas MA, Sheridan E, Iwama T, Eccles D, Smith GT, Kim JC, Kim KM, Sampson JR, Evans G, Tejpar S, Bodmer WF, Tomlinson IP, Houlston RS. Analysis of genetic and phenotypic heterogeneity in juvenile polyposis. Gut2000; 46: 656-660 [PMID: 10764709]
-
Gut2000
, vol.46
, pp. 656-660
-
-
Woodford-Richens, K1
Bevan, S2
Churchman, M3
Dowling, B4
Jones, D5
Norbury, CG6
Hodgson, SV7
Desai, D8
Neale, K9
Phillips, RK10
Young, J11
Leggett, B12
Dunlop, M13
Rozen, P14
Eng, C15
Markie, D16
Rodriguez-Bigas, MA17
Sheridan, E18
Iwama, T19
Eccles, D20
Smith, GT21
Kim, JC22
Kim, KM23
Sampson, JR24
Evans, G25
Tejpar, S26
Bodmer, WF27
Tomlinson, IP28
Houlston, RS.29
more..
-
109
-
-
0034795917
-
Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers
-
109 [PMID: 11583957]
-
109 Woodford-Richens KL, Rowan AJ, Poulsom R, Bevan S, Salovaara R, Aaltonen LA, Houlston RS, Wright NA, Tomlinson IP. Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers. Am J Pathol2001; 159: 1293-1300 [PMID: 11583957]
-
Am J Pathol2001
, vol.159
, pp. 1293-1300
-
-
Woodford-Richens, KL1
Rowan, AJ2
Poulsom, R3
Bevan, S4
Salovaara, R5
Aaltonen, LA6
Houlston, RS7
Wright, NA8
Tomlinson, IP.9
-
110
-
-
15444339425
-
Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome
-
110 [PMID: 9371495]
-
110 Marsh DJ, Roth S, Lunetta KL, Hemminki A, Dahia PL, Sistonen P, Zheng Z, Caron S, van Orsouw NJ, Bodmer WF, Cottrell SE, Dunlop MG, Eccles D, Hodgson SV, Järvinen H, Kellokumpu I, Markie D, Neale K, Phillips R, Rozen P, Syngal S, Vijg J, Tomlinson IP, Aaltonen LA, Eng C. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Cancer Res1997; 57: 5017-5021 [PMID: 9371495]
-
Cancer Res1997
, vol.57
, pp. 5017-5021
-
-
Marsh, DJ1
Roth, S2
Lunetta, KL3
Hemminki, A4
Dahia, PL5
Sistonen, P6
Zheng, Z7
Caron, S8
van Orsouw, NJ9
Bodmer, WF10
Cottrell, SE11
Dunlop, MG12
Eccles, D13
Hodgson, SV14
Järvinen, H15
Kellokumpu, I16
Markie, D17
Neale, K18
Phillips, R19
Rozen, P20
Syngal, S21
Vijg, J22
Tomlinson, IP23
Aaltonen, LA24
Eng, C.25
more..
-
111
-
-
84929589715
-
The clinical and biological signifcance of MIR-224 expression in colorectal cancer metastasis
-
111 Gut2015; Epub ahead of print [PMID: 25804630]
-
111 Ling H, Pickard K, Ivan C, Isella C, Ikuo M, Mitter R, Spizzo R, Bullock MD, Braicu C, Pileczki V, Vincent K, Pichler M, Stiegelbauer V, Hoefler G, Almeida MI, Hsiao A, Zhang X, Primrose JN, Packham GK, Liu K, Bojja K, Gafà R, Xiao L, Rossi S, Song JH, Vannini I, Fanini F, Kopetz S, Zweidler-McKay P, Wang X, Ionescu C, Irimie A, Fabbri M, Lanza G, Hamilton SR, Berindan-Neagoe I, Medico E, Mirnezami AH, Calin GA, Nicoloso MS. The clinical and biological signifcance of MIR-224 expression in colorectal cancer metastasis. Gut2015; Epub ahead of print [PMID: 25804630 DOI: 10.1136/gutjnl-2015-309372]
-
-
-
Ling, H1
Pickard, K2
Ivan, C3
Isella, C4
Ikuo, M5
Mitter, R6
Spizzo, R7
Bullock, MD8
Braicu, C9
Pileczki, V10
Vincent, K11
Pichler, M12
Stiegelbauer, V13
Hoefler, G14
Almeida, MI15
Hsiao, A16
Zhang, X17
Primrose, JN18
Packham, GK19
Liu, K20
Bojja, K21
Gafà, R22
Xiao, L23
Rossi, S24
Song, JH25
Vannini, I26
Fanini, F27
Kopetz, S28
Zweidler-McKay, P29
Wang, X30
Ionescu, C31
Irimie, A32
Fabbri, M33
Lanza, G34
Hamilton, SR35
Berindan-Neagoe, I36
Medico, E37
Mirnezami, AH38
Calin, GA39
Nicoloso, MS.40
more..
-
112
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
112 [PMID: 9425897]
-
112 Jenne DE, Reimann H, Nezu J, Friedel W, Loff S, Jeschke R, Müller O, Back W, Zimmer M. Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet1998; 18: 38-43 [PMID: 9425897]
-
Nat Genet1998
, vol.18
, pp. 38-43
-
-
Jenne, DE1
Reimann, H2
Nezu, J3
Friedel, W4
Loff, S5
Jeschke, R6
Müller, O7
Back, W8
Zimmer, M.9
-
113
-
-
13944265646
-
The hamartomatous polyposis syndromes: a clinical and molecular review
-
113 [PMID: 15667510]
-
113 Schreibman IR, Baker M, Amos C, McGarrity TJ. The hamartomatous polyposis syndromes: a clinical and molecular review. Am J Gastroenterol2005; 100: 476-490 [PMID: 15667510]
-
Am J Gastroenterol2005
, vol.100
, pp. 476-490
-
-
Schreibman, IR1
Baker, M2
Amos, C3
McGarrity, TJ.4
-
114
-
-
84909580799
-
Update on imaging of Peutz-Jeghers syndrome
-
114 [PMID: 25152588]
-
114 Tomas C, Soyer P, Dohan A, Dray X, Boudiaf M, Hoeffel C. Update on imaging of Peutz-Jeghers syndrome. World J Gastroenterol2014; 20: 10864-10875 [PMID: 25152588 DOI: 10.3748/wjg.v20.i31]
-
World J Gastroenterol2014
, vol.20
, pp. 10864-10875
-
-
Tomas, C1
Soyer, P2
Dohan, A3
Dray, X4
Boudiaf, M5
Hoeffel, C.6
-
115
-
-
33645838599
-
Peutz-Jeghers syndrome and management recommendations
-
115 [PMID: 16616343]
-
115 Giardiello FM, Trimbath JD. Peutz-Jeghers syndrome and management recommendations. Clin Gastroenterol Hepatol2006; 4: 408-415 [PMID: 16616343]
-
Clin Gastroenterol Hepatol2006
, vol.4
, pp. 408-415
-
-
Giardiello, FM1
Trimbath, JD.2
-
116
-
-
0034464147
-
Very high risk of cancer in familial Peutz-Jeghers syndrome
-
116 [PMID: 11113065]
-
116 Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, Booker S V, Cruz-Correa M, Offerhaus JA. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology2000; 119: 1447-1453 [PMID: 11113065]
-
Gastroenterology2000
, vol.119
, pp. 1447-1453
-
-
Giardiello, FM1
Brensinger, JD2
Tersmette, AC3
Goodman, SN4
Petersen, GM5
Booker, S V6
Cruz-Correa, M7
Offerhaus, JA.8
-
117
-
-
78651095553
-
High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome
-
117 [PMID: 21205875]
-
117 van Lier MG, Westerman AM, Wagner A, Looman CW, Wilson JH, de Rooij FW, Lemmens VE, Kuipers EJ, Mathus-Vliegen EM, van Leerdam ME. High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome. Gut2011; 60: 141-147 [PMID: 21205875 DOI: 10.1136/gut.2010.223750]
-
Gut2011
, vol.60
, pp. 141-147
-
-
van Lier, MG1
Westerman, AM2
Wagner, A3
Looman, CW4
Wilson, JH5
de Rooij, FW6
Lemmens, VE7
Kuipers, EJ8
Mathus-Vliegen, EM9
van Leerdam, ME.10
-
118
-
-
74249108693
-
Peutz-Jeghers syndrome: diagnostic and therapeutic approach
-
118 [PMID: 19916169]
-
118 Kopacova M, Tacheci I, Rejchrt S, Bures J. Peutz-Jeghers syndrome: diagnostic and therapeutic approach. World J Gastroenterol2009; 15: 5397-5408 [PMID: 19916169]
-
World J Gastroenterol2009
, vol.15
, pp. 5397-5408
-
-
Kopacova, M1
Tacheci, I2
Rejchrt, S3
Bures, J.4
-
119
-
-
0037125996
-
Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis
-
119 [PMID: 12218179]
-
119 Rossi DJ, Ylikorkala A, Korsisaari N, Salovaara R, Luukko K, Launonen V, Henkemeyer M, Ristimaki A, Aaltonen LA, Makela TP. Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis. Proc Natl Acad Sci USA2002; 99: 12327-12332 [PMID: 12218179]
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12327-12332
-
-
Rossi, DJ1
Ylikorkala, A2
Korsisaari, N3
Salovaara, R4
Luukko, K5
Launonen, V6
Henkemeyer, M7
Ristimaki, A8
Aaltonen, LA9
Makela, TP.10
-
120
-
-
1542269250
-
Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas
-
120 [PMID: 14760387]
-
120 Takeda H, Miyoshi H, Tamai Y, Oshima M, Taketo MM. Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas. Br J Cancer2004; 90: 701-704 [PMID: 14760387]
-
Br J Cancer2004
, vol.90
, pp. 701-704
-
-
Takeda, H1
Miyoshi, H2
Tamai, Y3
Oshima, M4
Taketo, MM.5
-
121
-
-
84893769960
-
Exome sequencing revealed novel germline mutations in Chinese Peutz-Jeghers syndrome patients
-
121 [PMID: 24154639]
-
121 Wang HH, Xie NN, Li QY, Hu YQ, Ren JL, Guleng B. Exome sequencing revealed novel germline mutations in Chinese Peutz-Jeghers syndrome patients. Dig Dis Sci2014; 59: 64-71 [PMID: 24154639 DOI: 10.1007/s10620-013-2875-7]
-
Dig Dis Sci2014
, vol.59
, pp. 64-71
-
-
Wang, HH1
Xie, NN2
Li, QY3
Hu, YQ4
Ren, JL5
Guleng, B.6
-
122
-
-
17344365130
-
Peutz-Jeghers syndrome: confrmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4
-
122 [PMID: 9399902]
-
122 Mehenni H, Blouin JL, Radhakrishna U, Bhardwaj SS, Bhardwaj K, Dixit VB, Richards KF, Bermejo-Fenoll A, Leal AS, Raval RC, Antonarakis SE. Peutz-Jeghers syndrome: confrmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4. Am J Hum Genet1997; 61: 1327-1334 [PMID: 9399902]
-
Am J Hum Genet1997
, vol.61
, pp. 1327-1334
-
-
Mehenni, H1
Blouin, JL2
Radhakrishna, U3
Bhardwaj, SS4
Bhardwaj, K5
Dixit, VB6
Richards, KF7
Bermejo-Fenoll, A8
Leal, AS9
Raval, RC10
Antonarakis, SE.11
-
123
-
-
0030820394
-
Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p
-
123 [PMID: 9288765]
-
123 Amos CI, Bali D, Thiel TJ, Anderson JP, Gourley I, Frazier ML, Lynch PM, Luchtefeld MA, Young A, McGarrity TJ, Seldin MF. Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. Cancer Res1997; 57: 3653-3656 [PMID: 9288765]
-
Cancer Res1997
, vol.57
, pp. 3653-3656
-
-
Amos, CI1
Bali, D2
Thiel, TJ3
Anderson, JP4
Gourley, I5
Frazier, ML6
Lynch, PM7
Luchtefeld, MA8
Young, A9
McGarrity, TJ10
Seldin, MF.11
-
124
-
-
0029934902
-
A pericentric inversion of chromosome six in a patient with Peutz-Jeghers’ syndrome and the use of FISH to localise the breakpoints on a genetic map
-
124 [PMID: 8698325]
-
124 Markie D, Huson S, Maher E, Davies A, Tomlinson I, Bodmer WF. A pericentric inversion of chromosome six in a patient with Peutz-Jeghers’ syndrome and the use of FISH to localise the breakpoints on a genetic map. Hum Genet1996; 98: 125-128 [PMID: 8698325]
-
Hum Genet1996
, vol.98
, pp. 125-128
-
-
Markie, D1
Huson, S2
Maher, E3
Davies, A4
Tomlinson, I5
Bodmer, WF.6
-
125
-
-
44449178672
-
Unregulated smooth-muscle myosin in human intestinal neoplasia
-
125 [PMID: 18391202]
-
125 Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IP, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL, Aaltonen LA. Unregulated smooth-muscle myosin in human intestinal neoplasia. Proc Natl Acad Sci USA2008; 105: 5513-5518 [PMID: 18391202 DOI: 10.1073/pnas.0801213105]
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5513-5518
-
-
Alhopuro, P1
Phichith, D2
Tuupanen, S3
Sammalkorpi, H4
Nybondas, M5
Saharinen, J6
Robinson, JP7
Yang, Z8
Chen, LQ9
Orntoft, T10
Mecklin, JP11
Järvinen, H12
Eng, C13
Moeslein, G14
Shibata, D15
Houlston, RS16
Lucassen, A17
Tomlinson, IP18
Launonen, V19
Ristimäki, A20
Arango, D21
Karhu, A22
Sweeney, HL23
Aaltonen, LA.24
more..
-
126
-
-
25444524851
-
Mutations in the human LKB1/STK11 gene
-
126 [PMID: 16110486]
-
126 Launonen V. Mutations in the human LKB1/STK11 gene. Hum Mutat2005; 26: 291-297 [PMID: 16110486]
-
Hum Mutat2005
, vol.26
, pp. 291-297
-
-
Launonen, V.1
-
127
-
-
0008944606
-
Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer
-
127 [PMID: 9731485]
-
127 Dong SM, Kim KM, Kim SY, Shin MS, Na EY, Lee SH, Park WS, Yoo NJ, Jang JJ, Yoon CY, Kim JW, Kim SY, Yang YM, Kim SH, Kim CS, Lee JY. Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer. Cancer Res1998; 58:3787-3790 [PMID: 9731485]
-
Cancer Res1998
, vol.58
, pp. 3787-3790
-
-
Dong, SM1
Kim, KM2
Kim, SY3
Shin, MS4
Na, EY5
Lee, SH6
Park, WS7
Yoo, NJ8
Jang, JJ9
Yoon, CY10
Kim, JW11
Kim, SY12
Yang, YM13
Kim, SH14
Kim, CS15
Lee, JY.16
-
128
-
-
14444272759
-
STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer
-
128 [PMID: 9809980]
-
128 Resta N, Simone C, Mareni C, Montera M, Gentile M, Susca F, Gristina R, Pozzi S, Bertario L, Bufo P, Carlomagno N, Ingrosso M, Rossini FP, Tenconi R, Guanti G. STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer. Cancer Res1998; 58: 4799-4801 [PMID: 9809980]
-
Cancer Res1998
, vol.58
, pp. 4799-4801
-
-
Resta, N1
Simone, C2
Mareni, C3
Montera, M4
Gentile, M5
Susca, F6
Gristina, R7
Pozzi, S8
Bertario, L9
Bufo, P10
Carlomagno, N11
Ingrosso, M12
Rossini, FP13
Tenconi, R14
Guanti, G.15
-
129
-
-
34347244948
-
STK11/LKB1 germline mutations in the first Peutz-Jeghers syndrome patients identified in Slovakia
-
129 [PMID: 17319781]
-
129 Bartosova Z, Zavodna K, Krivulcik T, Usak J, Mlkva I, Kruzliak T, Hromec J, Usakova V, Kopecka I, Veres P, Bartosova Z, Bujalkova M. STK11/LKB1 germline mutations in the first Peutz-Jeghers syndrome patients identified in Slovakia. Neoplasma2007; 54: 101-107 [PMID: 17319781]
-
Neoplasma2007
, vol.54
, pp. 101-107
-
-
Bartosova, Z1
Zavodna, K2
Krivulcik, T3
Usak, J4
Mlkva, I5
Kruzliak, T6
Hromec, J7
Usakova, V8
Kopecka, I9
Veres, P10
Bartosova, Z11
Bujalkova, M.12
-
130
-
-
0034610730
-
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
-
130 [PMID: 10644993]
-
130 Esteller M, Avizienyte E, Corn PG, Lothe RA, Baylin SB, Aaltonen LA, Herman JG. Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome. Oncogene2000; 19: 164-168 [PMID: 10644993]
-
Oncogene2000
, vol.19
, pp. 164-168
-
-
Esteller, M1
Avizienyte, E2
Corn, PG3
Lothe, RA4
Baylin, SB5
Aaltonen, LA6
Herman, JG.7
-
131
-
-
0037089467
-
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice
-
131 [PMID: 11956081]
-
131 Miyoshi H, Nakau M, Ishikawa TO, Seldin MF, Oshima M, Taketo MM. Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Cancer Res2002; 62: 2261-2266 [PMID: 11956081]
-
Cancer Res2002
, vol.62
, pp. 2261-2266
-
-
Miyoshi, H1
Nakau, M2
Ishikawa, TO3
Seldin, MF4
Oshima, M5
Taketo, MM.6
-
132
-
-
0037068461
-
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
-
132 [PMID: 12226664]
-
132 Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature2002; 419: 162-167 [PMID: 12226664]
-
Nature2002
, vol.419
, pp. 162-167
-
-
Bardeesy, N1
Sinha, M2
Hezel, AF3
Signoretti, S4
Hathaway, NA5
Sharpless, NE6
Loda, M7
Carrasco, DR8
DePinho, RA.9
-
133
-
-
47349129383
-
Molecular insights into Peutz-Jeghers syndrome: two probands with a germline mutation of LKB1
-
133 [PMID: 18600394]
-
133 Hosogi H, Nagayama S, Kawamura J, Koshiba Y, Nomura A, Itami A, Okabe H, Satoh S, Watanabe G, Sakai Y. Molecular insights into Peutz-Jeghers syndrome: two probands with a germline mutation of LKB1. J Gastroenterol2008; 43: 492-497 [PMID: 18600394 DOI: 10.1007/s00535-008-2185-6]
-
J Gastroenterol2008
, vol.43
, pp. 492-497
-
-
Hosogi, H1
Nagayama, S2
Kawamura, J3
Koshiba, Y4
Nomura, A5
Itami, A6
Okabe, H7
Satoh, S8
Watanabe, G9
Sakai, Y.10
-
134
-
-
0037422027
-
Hereditary colorectal cancer
-
134 [PMID: 12621137]
-
134 Lynch HT, de la Chapelle A. Hereditary colorectal cancer. N Engl J Med2003; 348: 919-932 [PMID: 12621137]
-
N Engl J Med2003
, vol.348
, pp. 919-932
-
-
Lynch, HT1
de la Chapelle, A.2
-
135
-
-
0034799747
-
The colon cancer burden of genetically defned hereditary nonpolyposis colon cancer
-
135 [PMID: 11606497]
-
135 Samowitz WS, Curtin K, Lin HH, Robertson MA, Schaffer D, Nichols M, Gruenthal K, Leppert MF, Slattery ML. The colon cancer burden of genetically defned hereditary nonpolyposis colon cancer. Gastroenterology2001; 121: 830-838 [PMID: 11606497]
-
Gastroenterology2001
, vol.121
, pp. 830-838
-
-
Samowitz, WS1
Curtin, K2
Lin, HH3
Robertson, MA4
Schaffer, D5
Nichols, M6
Gruenthal, K7
Leppert, MF8
Slattery, ML.9
-
136
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
136 [PMID: 9618505]
-
136 Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA1998; 95: 6870-6875 [PMID: 9618505]
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6870-6875
-
-
Herman, JG1
Umar, A2
Polyak, K3
Graff, JR4
Ahuja, N5
Issa, JP6
Markowitz, S7
Willson, JK8
Hamilton, SR9
Kinzler, KW10
Kane, MF11
Kolodner, RD12
Vogelstein, B13
Kunkel, TA14
Baylin, SB.15
-
137
-
-
84905455346
-
Sporadic early-onset colorectal cancer is a specifc sub-type of cancer: a morphological, molecular and genetics study
-
137 [PMID: 25083765]
-
137 Kirzin S, Marisa L, Guimbaud R, De Reynies A, Legrain M, Laurent-Puig P, Cordelier P, Pradère B, Bonnet D, Meggetto F, Portier G, Brousset P, Selves J. Sporadic early-onset colorectal cancer is a specifc sub-type of cancer: a morphological, molecular and genetics study. PLoS One2014; 9: e103159 [PMID: 25083765 DOI: 10.1371/journal.pone.0103159]
-
PLoS One2014
, vol.9
, pp. e103159
-
-
Kirzin, S1
Marisa, L2
Guimbaud, R3
De Reynies, A4
Legrain, M5
Laurent-Puig, P6
Cordelier, P7
Pradère, B8
Bonnet, D9
Meggetto, F10
Portier, G11
Brousset, P12
Selves, J.13
-
138
-
-
77449130761
-
Microsatellite instability in colorectal cancer
-
138 e3 [PMID: 20420947]
-
138 Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology2010; 138: 2073-2087.e3 [PMID: 20420947 DOI: 10.1053/j.gastro.2009.12.064]
-
Gastroenterology2010
, vol.138
, pp. 2073-2087
-
-
Boland, CR1
Goel, A.2
-
139
-
-
67649506174
-
Genetic prognostic and predictive markers in colorectal cancer
-
139 [PMID: 19536109]
-
139 Walther A, Johnstone E, Swanton C, Midgley R, Tomlinson I, Kerr D. Genetic prognostic and predictive markers in colorectal cancer. Nat Rev Cancer2009; 9: 489-499 [PMID: 19536109 DOI: 10.1038/nrc2645]
-
Nat Rev Cancer2009
, vol.9
, pp. 489-499
-
-
Walther, A1
Johnstone, E2
Swanton, C3
Midgley, R4
Tomlinson, I5
Kerr, D.6
-
140
-
-
42649126002
-
Clinicopathologic and molecular features of sporadic microsatelliteand chromosomal-stable colorectal cancers
-
140 [PMID: 18193434]
-
140 Cai G, Xu Y, Lu H, Shi Y, Lian P, Peng J, Du X, Zhou X, Guan Z, Shi D, Cai S. Clinicopathologic and molecular features of sporadic microsatelliteand chromosomal-stable colorectal cancers. Int J Colorectal Dis2008; 23: 365-373 [PMID: 18193434 DOI: 10.1007/s00384-007-0423-7]
-
Int J Colorectal Dis2008
, vol.23
, pp. 365-373
-
-
Cai, G1
Xu, Y2
Lu, H3
Shi, Y4
Lian, P5
Peng, J6
Du, X7
Zhou, X8
Guan, Z9
Shi, D10
Cai, S.11
-
141
-
-
84155165379
-
A distinct DNA methylation profle associated with microsatellite and chromosomal stable sporadic colorectal cancers
-
141 [PMID: 21455990]
-
141 Silver A, Sengupta N, Propper D, Wilson P, Hagemann T, Patel A, Parker A, Ghosh A, Feakins R, Dorudi S, Suraweera N. A distinct DNA methylation profle associated with microsatellite and chromosomal stable sporadic colorectal cancers. Int J Cancer2012; 130: 1082-1092 [PMID: 21455990 DOI: 10.1002/ijc.26104]
-
Int J Cancer2012
, vol.130
, pp. 1082-1092
-
-
Silver, A1
Sengupta, N2
Propper, D3
Wilson, P4
Hagemann, T5
Patel, A6
Parker, A7
Ghosh, A8
Feakins, R9
Dorudi, S10
Suraweera, N.11
-
142
-
-
37649021203
-
Colorectal carcinoma in childhood and adolescence: a clinicopathologic review
-
142 [PMID: 18089879]
-
142 Hill DA, Furman WL, Billups CA, Riedley SE, Cain AM, Rao BN, Pratt CB, Spunt SL. Colorectal carcinoma in childhood and adolescence: a clinicopathologic review. J Clin Oncol2007; 25: 5808-5814 [PMID: 18089879]
-
J Clin Oncol2007
, vol.25
, pp. 5808-5814
-
-
Hill, DA1
Furman, WL2
Billups, CA3
Riedley, SE4
Cain, AM5
Rao, BN6
Pratt, CB7
Spunt, SL.8
-
143
-
-
35748967324
-
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer
-
143 [PMID: 17716371]
-
143 Lanza G, Ferracin M, Gafà R, Veronese A, Spizzo R, Pichiorri F, Liu CG, Calin GA, Ctabel 6roce CM, Negrini M. mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer. Mol Cancer2007; 6: 54 [PMID: 17716371 DOI: 10.1186/1476-4598-6-54]
-
Mol Cancer2007
, vol.6
, pp. 54
-
-
Lanza, G1
Ferracin, M2
Gafà, R3
Veronese, A4
Spizzo, R5
Pichiorri, F6
Liu, CG7
Calin, GA8
Ctabel 6roce, CM9
Negrini, M.10
-
144
-
-
84863092406
-
Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer
-
144 [PMID: 22719182]
-
144 Yamamoto H, Adachi Y, Taniguchi H, Kunimoto H, Nosho K, Suzuki H, Shinomura Y. Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer. World J Gastroenterol2012; 18: 2745-2755 [PMID: 22719182 DOI: 10.3748/wjg.v18.i22.2745]
-
World J Gastroenterol2012
, vol.18
, pp. 2745-2755
-
-
Yamamoto, H1
Adachi, Y2
Taniguchi, H3
Kunimoto, H4
Nosho, K5
Suzuki, H6
Shinomura, Y.7
-
145
-
-
84879842001
-
BMPR1A mutations in early-onset colorectal cancer with mismatch repair profciency
-
145 [PMID: 23057600]
-
145 Fernandez-Rozadilla C, Brea-Fernández A, Bessa X, Alvarez-Urturi C, Abulí A, Clofent J, Payá A, Jover R, Xicola R, Llor X, Andreu M, Castells A, Carracedo A, Castellví-Bel S, Ruiz-Ponte C. BMPR1A mutations in early-onset colorectal cancer with mismatch repair profciency. Clin Genet2013; 84: 94-96 [PMID: 23057600 DOI: 10.1111/cge.12023]
-
Clin Genet2013
, vol.84
, pp. 94-96
-
-
Fernandez-Rozadilla, C1
Brea-Fernández, A2
Bessa, X3
Alvarez-Urturi, C4
Abulí, A5
Clofent, J6
Payá, A7
Jover, R8
Xicola, R9
Llor, X10
Andreu, M11
Castells, A12
Carracedo, A13
Castellví-Bel, S14
Ruiz-Ponte, C.15
-
146
-
-
84890442698
-
Network cluster analysis of protein-protein interaction network identified biomarker for early onset colorectal cancer
-
146 [PMID: 24197691]
-
146 Luo T, Wu S, Shen X, Li L. Network cluster analysis of protein-protein interaction network identified biomarker for early onset colorectal cancer. Mol Biol Rep2013; 40: 6561-6568 [PMID: 24197691 DOI: 10.1007/s11033-013-2694-0]
-
Mol Biol Rep2013
, vol.40
, pp. 6561-6568
-
-
Luo, T1
Wu, S2
Shen, X3
Li, L.4
-
147
-
-
84891668986
-
Microsatellite instability status affects gene expression profiles in early onset colorectal cancer patients
-
147 [PMID: 23992855]
-
147 Ak S, Tunca B, Yilmazlar T, Tezcan G, Cecener G, Egeli U, Ozturk E, Yerci O, Ertürk E, Zorluoglu A. Microsatellite instability status affects gene expression profiles in early onset colorectal cancer patients. J Surg Res2013; 185: 626-637 [PMID: 23992855 DOI: 10.1016/j.jss.2013.07.014]
-
J Surg Res2013
, vol.185
, pp. 626-637
-
-
Ak, S1
Tunca, B2
Yilmazlar, T3
Tezcan, G4
Cecener, G5
Egeli, U6
Ozturk, E7
Yerci, O8
Ertürk, E9
Zorluoglu, A.10
-
148
-
-
0026561237
-
Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies
-
148 [PMID: 1371204]
-
148 Moll R, Löwe A, Laufer J, Franke WW. Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol1992; 140: 427-447 [PMID: 1371204]
-
Am J Pathol1992
, vol.140
, pp. 427-447
-
-
Moll, R1
Löwe, A2
Laufer, J3
Franke, WW.4
-
149
-
-
84876414952
-
Overexpression of CK20, MAP3K8 and EIF5A correlates with poor prognosis in early-onset colorectal cancer patients
-
149 [PMID: 23322277]
-
149 Tunca B, Tezcan G, Cecener G, Egeli U, Zorluoglu A, Yilmazlar T, Ak S, Yerci O, Ozturk E, Umut G, Evrensel T. Overexpression of CK20, MAP3K8 and EIF5A correlates with poor prognosis in early-onset colorectal cancer patients. J Cancer Res Clin Oncol2013; 139: 691-702 [PMID: 23322277 DOI: 10.1007/s00432-013-1372-x]
-
J Cancer Res Clin Oncol2013
, vol.139
, pp. 691-702
-
-
Tunca, B1
Tezcan, G2
Cecener, G3
Egeli, U4
Zorluoglu, A5
Yilmazlar, T6
Ak, S7
Yerci, O8
Ozturk, E9
Umut, G10
Evrensel, T.11
-
150
-
-
2542476370
-
Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability
-
150 [PMID: 15166663]
-
150 McGregor DK, Wu TT, Rashid A, Luthra R, Hamilton SR. Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability. Am J Surg Pathol2004; 28: 712-718 [PMID: 15166663]
-
Am J Surg Pathol2004
, vol.28
, pp. 712-718
-
-
McGregor, DK1
Wu, TT2
Rashid, A3
Luthra, R4
Hamilton, SR.5
-
151
-
-
44949147974
-
REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis
-
151 [PMID: 18452172]
-
151 Astrosini C, Roeefzaad C, Dai Y Y, Dieckgraefe BK, Jöns T, Kem-mner W. REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis. Int J Cancer2008; 123: 409-413 [PMID: 18452172 DOI: 10.1002/ijc.23466]
-
Int J Cancer2008
, vol.123
, pp. 409-413
-
-
Astrosini, C1
Roeefzaad, C2
Dai, Y Y3
Dieckgraefe, BK4
Jöns, T5
Kem-mner, W.6
-
152
-
-
0001382298
-
Ectopic expression of reg protein: A marker of colorectal mucosa at risk for neoplasia
-
152 ; discussion 201-202 [PMID: 9834348]
-
152 Zenilman ME, Kim S, Levine BA, Lee C, Steinberg JJ. Ectopic expression of reg protein: A marker of colorectal mucosa at risk for neoplasia. J Gastrointest Surg1997; 1: 194-201; discussion 201-202 [PMID: 9834348]
-
J Gastrointest Surg1997
, vol.1
, pp. 194-201
-
-
Zenilman, ME1
Kim, S2
Levine, BA3
Lee, C4
Steinberg, JJ.5
-
153
-
-
0032588360
-
pap, reg Ialpha and reg Ibeta mRNAs are concomitantly up-regulated during human colorectal carcinogenesis
-
153 [PMID: 10328217]
-
153 Rechreche H, Montalto G, Mallo GV, Vasseur S, Marasa L, Soubeyran P, Dagorn JC, Iovanna JL. pap, reg Ialpha and reg Ibeta mRNAs are concomitantly up-regulated during human colorectal carcinogenesis. Int J Cancer1999; 81: 688-694 [PMID: 10328217]
-
Int J Cancer1999
, vol.81
, pp. 688-694
-
-
Rechreche, H1
Montalto, G2
Mallo, GV3
Vasseur, S4
Marasa, L5
Soubeyran, P6
Dagorn, JC7
Iovanna, JL.8
-
154
-
-
84871720551
-
Analysis of colorectal cancers in British Bangladeshi identifes early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
-
154 [PMID: 23286373]
-
154 Sengupta N, Yau C, Sakthianandeswaren A, Mouradov D, Gibbs P, Suraweera N, Cazier JB, Polanco-Echeverry G, Ghosh A, Thaha M, Ahmed S, Feakins R, Propper D, Dorudi S, Sieber O, Silver A, Lai C. Analysis of colorectal cancers in British Bangladeshi identifes early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion. Mol Cancer2013; 12: 1 [PMID: 23286373 DOI: 10.1186/1476-4598-12-1]
-
Mol Cancer2013
, vol.12
, pp. 1
-
-
Sengupta, N1
Yau, C2
Sakthianandeswaren, A3
Mouradov, D4
Gibbs, P5
Suraweera, N6
Cazier, JB7
Polanco-Echeverry, G8
Ghosh, A9
Thaha, M10
Ahmed, S11
Feakins, R12
Propper, D13
Dorudi, S14
Sieber, O15
Silver, A16
Lai, C.17
-
155
-
-
84924049990
-
Sporadic microsatellite instability-high colon cancers rarely display immu-nohistochemical evidence of Wnt signaling activation
-
155 [PMID: 25602793]
-
155 Panarelli NC, Vaughn C P, Samowitz WS, Yantiss RK. Sporadic microsatellite instability-high colon cancers rarely display immu-nohistochemical evidence of Wnt signaling activation. Am J Surg Pathol2015; 39: 313-317 [PMID: 25602793 DOI: 10.1097/PAS.00 00000000000380]
-
Am J Surg Pathol2015
, vol.39
, pp. 313-317
-
-
Panarelli, NC1
Vaughn, C P2
Samowitz, WS3
Yantiss, RK.4
-
156
-
-
34547405167
-
Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer
-
156 [PMID: 17453358]
-
156 Loughrey MB, Waring PM, Tan A, Trivett M, Kovalenko S, Beshay V, Young MA, McArthur G, Boussioutas A, Dobrovic A. Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer2007; 6: 301-310 [PMID: 17453358]
-
Fam Cancer2007
, vol.6
, pp. 301-310
-
-
Loughrey, MB1
Waring, PM2
Tan, A3
Trivett, M4
Kovalenko, S5
Beshay, V6
Young, MA7
McArthur, G8
Boussioutas, A9
Dobrovic, A.10
-
157
-
-
84906269215
-
MicroRNA expression patterns of tumors in early-onset colorectal cancer patients
-
157 [PMID: 24746948]
-
157 Ak S, Tunca B, Tezcan G, Cecener G, Egeli U, Yilmazlar T, Ozturk E, Yerci O. MicroRNA expression patterns of tumors in early-onset colorectal cancer patients. J Surg Res2014; 191: 113-122 [PMID: 24746948 DOI: 10.1016/j.jss.2014.03.057]
-
J Surg Res2014
, vol.191
, pp. 113-122
-
-
Ak, S1
Tunca, B2
Tezcan, G3
Cecener, G4
Egeli, U5
Yilmazlar, T6
Ozturk, E7
Yerci, O.8
-
158
-
-
61349127117
-
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function
-
158 [PMID: 19219043]
-
158 Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, Calin GA, Rossi S, Fernandez AF, Carneiro F, Oliveira C, Ferreira B, Liu CG, Villanueva A, Capella G, Schwartz S, Shiekhattar R, Esteller M. A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet2009; 41: 365-370 [PMID: 19219043 DOI: 10.1038/ng.317]
-
Nat Genet2009
, vol.41
, pp. 365-370
-
-
Melo, SA1
Ropero, S2
Moutinho, C3
Aaltonen, LA4
Yamamoto, H5
Calin, GA6
Rossi, S7
Fernandez, AF8
Carneiro, F9
Oliveira, C10
Ferreira, B11
Liu, CG12
Villanueva, A13
Capella, G14
Schwartz, S15
Shiekhattar, R16
Esteller, M.17
-
159
-
-
84924583833
-
Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy
-
159 [PMID: 25301724]
-
159 Martino-Echarri E, Henderson BR, Brocardo MG. Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. Oncotarget2014; 5: 9889-9900 [PMID: 25301724]
-
Oncotarget2014
, vol.5
, pp. 9889-9900
-
-
Martino-Echarri, E1
Henderson, BR2
Brocardo, MG.3
-
160
-
-
14544300998
-
Systematic review of microsate-llite instability and colorectal cancer prognosis
-
160 [PMID: 15659508]
-
160 Popat S, Hubner R, Houlston RS. Systematic review of microsate-llite instability and colorectal cancer prognosis. J Clin Oncol2005; 23: 609-618 [PMID: 15659508]
-
J Clin Oncol2005
, vol.23
, pp. 609-618
-
-
Popat, S1
Hubner, R2
Houlston, RS.3
-
161
-
-
84877126189
-
Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
-
161 [PMID: 23235802]
-
161 Merok MA, Ahlquist T, Røyrvik EC, Tufteland KF, Hektoen M, Sjo OH, Mala T, Svindland A, Lothe RA, Nesbakken A. Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series. Ann Oncol2013; 24: 1274-1282 [PMID: 23235802 DOI: 10.1093/annonc/mds614]
-
Ann Oncol2013
, vol.24
, pp. 1274-1282
-
-
Merok, MA1
Ahlquist, T2
Røyrvik, EC3
Tufteland, KF4
Hektoen, M5
Sjo, OH6
Mala, T7
Svindland, A8
Lothe, RA9
Nesbakken, A.10
-
162
-
-
0036533524
-
Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status
-
162 [PMID: 11920608]
-
162 Violette S, Poulain L, Dussaulx E, Pepin D, Faussat AM, Chambaz J, Lacorte JM, Staedel C, Lesuffeur T. Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status. Int J Cancer2002; 98: 498-504 [PMID: 11920608]
-
Int J Cancer2002
, vol.98
, pp. 498-504
-
-
Violette, S1
Poulain, L2
Dussaulx, E3
Pepin, D4
Faussat, AM5
Chambaz, J6
Lacorte, JM7
Staedel, C8
Lesuffeur, T.9
-
163
-
-
30044442435
-
Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas
-
163 [PMID: 16401477]
-
163 Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology2006; 130: 137-149 [PMID: 16401477]
-
Gastroenterology2006
, vol.130
, pp. 137-149
-
-
Bishnupuri, KS1
Luo, Q2
Murmu, N3
Houchen, CW4
Anant, S5
Dieckgraefe, BK.6
-
164
-
-
84893669133
-
Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro
-
164 [PMID: 24275137]
-
164 Deng J, Lei W, Fu JC, Zhang L, Li JH, Xiong JP. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro. Biochem Biophys Res Commun2014; 443: 789-795 [PMID: 24275137 DOI: 10.1016/j.bbrc.2013.11.064]
-
Biochem Biophys Res Commun2014
, vol.443
, pp. 789-795
-
-
Deng, J1
Lei, W2
Fu, JC3
Zhang, L4
Li, JH5
Xiong, JP.6
-
165
-
-
84857924235
-
-
165 [updated 2014 Apr 25]. Rockville, MD: National Cancer Institute
-
165 Institute NC. Targeted Cancer Therapies. [updated 2014 Apr 25]. Rockville, MD: National Cancer Institute, 2014
-
(2014)
Targeted Cancer Therapies
-
-
Institute, NC.1
-
166
-
-
84872921660
-
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
-
166 [PMID: 23177514]
-
166 Grothey A, Van Cutsem E, Sobrero A, Siena S, Falcone A, Ychou M, Humblet Y, Bouché O, Mineur L, Barone C, Adenis A, Tabernero J, Yoshino T, Lenz HJ, Goldberg RM, Sargent DJ, Cihon F, Cupit L, Wagner A, Laurent D. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet2013; 381: 303-312 [PMID: 23177514 DOI: 10.1016/S0140-6736(12)61900-X]
-
Lancet2013
, vol.381
, pp. 303-312
-
-
Grothey, A1
Van Cutsem, E2
Sobrero, A3
Siena, S4
Falcone, A5
Ychou, M6
Humblet, Y7
Bouché, O8
Mineur, L9
Barone, C10
Adenis, A11
Tabernero, J12
Yoshino, T13
Lenz, HJ14
Goldberg, RM15
Sargent, DJ16
Cihon, F17
Cupit, L18
Wagner, A19
Laurent, D.20
more..
-
167
-
-
84867047384
-
Addition of afibercept to fuorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
-
167 [PMID: 22949147]
-
167 Van Cutsem E, Tabernero J, Lakomy R, Prenen H, Prausová J, Macarulla T, Ruff P, van Hazel GA, Moiseyenko V, Ferry D, McKendrick J, Polikoff J, Tellier A, Castan R, Allegra C. Addition of afibercept to fuorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol2012; 30: 3499-3506 [PMID: 22949147]
-
J Clin Oncol2012
, vol.30
, pp. 3499-3506
-
-
Van Cutsem, E1
Tabernero, J2
Lakomy, R3
Prenen, H4
Prausová, J5
Macarulla, T6
Ruff, P7
van Hazel, GA8
Moiseyenko, V9
Ferry, D10
McKendrick, J11
Polikoff, J12
Tellier, A13
Castan, R14
Allegra, C.15
-
168
-
-
79955636598
-
Molecularly targeted therapy for metastatic colon cancer: proven treatments and promising new agents
-
168 [PMID: 21464866]
-
168 El Zouhairi M, Charabaty A, Pishvaian MJ. Molecularly targeted therapy for metastatic colon cancer: proven treatments and promising new agents. Gastrointest Cancer Res2011; 4: 15-21 [PMID: 21464866]
-
Gastrointest Cancer Res2011
, vol.4
, pp. 15-21
-
-
El Zouhairi, M1
Charabaty, A2
Pishvaian, MJ.3
-
169
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
169 [PMID: 15269313]
-
169 Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med2004; 351: 337-345 [PMID: 15269313]
-
N Engl J Med2004
, vol.351
, pp. 337-345
-
-
Cunningham, D1
Humblet, Y2
Siena, S3
Khayat, D4
Bleiberg, H5
Santoro, A6
Bets, D7
Mueser, M8
Harstrick, A9
Verslype, C10
Chau, I11
Van Cutsem, E.12
-
170
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
-
170 [PMID: 19188670]
-
170 Allegra CJ, Jessup JM, Somerfeld MR, Hamilton SR, Hammond EH, Hayes DF, McAllister PK, Morton RF, Schilsky RL. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol2009; 27: 2091-2096 [PMID: 19188670 DOI: 10.1200/JCO.2009.21.9170]
-
J Clin Oncol2009
, vol.27
, pp. 2091-2096
-
-
Allegra, CJ1
Jessup, JM2
Somerfeld, MR3
Hamilton, SR4
Hammond, EH5
Hayes, DF6
McAllister, PK7
Morton, RF8
Schilsky, RL.9
-
171
-
-
84978062508
-
Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer
-
171 [PMID: 25815366]
-
171 Knickelbein K, Zhang L. Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer. Genes Dis2015; 2: 4-12 [PMID: 25815366]
-
Genes Dis2015
, vol.2
, pp. 4-12
-
-
Knickelbein, K1
Zhang, L.2
-
172
-
-
84903301924
-
The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis
-
172 [PMID: 24666267]
-
172 Therkildsen C, Bergmann TK, Henrichsen-Schnack T, Ladelund S, Nilbert M. The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis. Acta Oncol2014; 53: 852-864 [PMID: 24666267 DOI: 10.3109/0284186X.2014.895036]
-
Acta Oncol2014
, vol.53
, pp. 852-864
-
-
Therkildsen, C1
Bergmann, TK2
Henrichsen-Schnack, T3
Ladelund, S4
Nilbert, M.5
-
173
-
-
50349091081
-
Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer
-
173 [PMID: 18519771]
-
173 French AJ, Sargent DJ, Burgart LJ, Foster NR, Kabat BF, Goldberg R, Shepherd L, Windschitl HE, Thibodeau SN. Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer. Clin Cancer Res2008; 14: 3408-3415 [PMID: 18519771 DOI: 10.1158/1078-0432.CCR-07-1489]
-
Clin Cancer Res2008
, vol.14
, pp. 3408-3415
-
-
French, AJ1
Sargent, DJ2
Burgart, LJ3
Foster, NR4
Kabat, BF5
Goldberg, R6
Shepherd, L7
Windschitl, HE8
Thibodeau, SN.9
-
174
-
-
79952419581
-
Systemic Therapy for Metastatic Colorectal Cancer: Patterns of Chemotherapy and Biologic Therapy Use in US Medical Oncology Practice
-
174 [PMID: 21358960]
-
174 Hess GP, Wang PF, Quach D, Barber B, Zhao Z. Systemic Therapy for Metastatic Colorectal Cancer: Patterns of Chemotherapy and Biologic Therapy Use in US Medical Oncology Practice. J Oncol Pract2010; 6: 301-307 [PMID: 21358960 DOI: 10.1200/JOP.2010.000072]
-
J Oncol Pract2010
, vol.6
, pp. 301-307
-
-
Hess, GP1
Wang, PF2
Quach, D3
Barber, B4
Zhao, Z.5
-
175
-
-
84874725276
-
The development of regorafenib and its current and potential future role in cancer therapy
-
175 [PMID: 23462625]
-
175 Davis SL, Eckhardt SG, Messersmith WA, Jimeno A. The development of regorafenib and its current and potential future role in cancer therapy. Drugs Today (Barc) 2013; 49: 105-115 [PMID: 23462625 DOI: 10.1358/dot.2013.49.2.1930525]
-
(2013)
Drugs Today (Barc)
, vol.49
, pp. 105-115
-
-
Davis, SL1
Eckhardt, SG2
Messersmith, WA3
Jimeno, A.4
-
176
-
-
0037231664
-
Cytokine traps: multi-component, high-affnity blockers of cytokine action
-
176 [PMID: 12483208]
-
176 Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler-Stec EM, Hartnett C, Pyles EA, Xu X, Daly TJ, Young MR, Fandl JP, Lee F, Carver S, McNay J, Bailey K, Ramakanth S, Hutabarat R, Huang TT, Radziejewski C, Yancopoulos GD, Stahl N. Cytokine traps: multi-component, high-affnity blockers of cytokine action. Nat Med2003; 9: 47-52 [PMID: 12483208]
-
Nat Med2003
, vol.9
, pp. 47-52
-
-
Economides, AN1
Carpenter, LR2
Rudge, JS3
Wong, V4
Koehler-Stec, EM5
Hartnett, C6
Pyles, EA7
Xu, X8
Daly, TJ9
Young, MR10
Fandl, JP11
Lee, F12
Carver, S13
McNay, J14
Bailey, K15
Ramakanth, S16
Hutabarat, R17
Huang, TT18
Radziejewski, C19
Yancopoulos, GD20
Stahl, N.21
more..
|