-
2
-
-
77955273537
-
-
Lyon, France: International Agency for Research on Cancer, Available online, Accessed: August 30, 2012
-
Ferlay J, Shin HR, Bray F, et al. GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer, 2010. Available online: http://www-dep.iarc.fr/. Accessed: August 30, 2012.
-
(2010)
GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
-
3
-
-
57449097359
-
Feasibility of screening for Lynch syndrome among patients with colorectal cancer
-
Hampel H, Frankel WL, Martin E, et al. Feasibility of screening for Lynch syndrome among patients with colorectal cancer. J Clin Oncol 2008;26:5783-8.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5783-5788
-
-
Hampel, H.1
Frankel, W.L.2
Martin, E.3
-
4
-
-
24144463165
-
Lynch syndrome genes
-
Peltomäki P. Lynch syndrome genes. Fam Cancer 2005;4:227-32.
-
(2005)
Fam Cancer
, vol.4
, pp. 227-232
-
-
Peltomäki, P.1
-
5
-
-
0028221943
-
Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
-
Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 1994;368:258-61.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
-
6
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993;75:1027-38.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
-
7
-
-
0027145633
-
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-25.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
8
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
Miyaki M, Konishi M, Tanaka K, et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 1997;17:271-2.
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
-
9
-
-
0027933070
-
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
-
Nicolaides NC, Papadopoulos N, Liu B, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 1994;371:75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
10
-
-
0029862873
-
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
-
Vasen HF, Wijnen JT, Menko FH, et al. Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis. Gastroenterology 1996;110:1020-7.
-
(1996)
Gastroenterology
, vol.110
, pp. 1020-1027
-
-
Vasen, H.F.1
Wijnen, J.T.2
Menko, F.H.3
-
11
-
-
0343307082
-
Rectal cancer risk in hereditary nonpolyposis colorectal cancer after abdominal colectomy. International Collaborative Group on HNPCC
-
Rodríguez-Bigas MA, Vasen HF, Pekka-Mecklin J, et al. Rectal cancer risk in hereditary nonpolyposis colorectal cancer after abdominal colectomy. International Collaborative Group on HNPCC. Ann Surg 1997;225:202-7.
-
(1997)
Ann Surg
, vol.225
, pp. 202-207
-
-
Rodríguez-Bigas, M.A.1
Vasen, H.F.2
Pekka-Mecklin, J.3
-
12
-
-
67650924286
-
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
-
Lynch HT, Lynch PM, Lanspa SJ, et al. Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet 2009;76:1-18.
-
(2009)
Clin Genet
, vol.76
, pp. 1-18
-
-
Lynch, H.T.1
Lynch, P.M.2
Lanspa, S.J.3
-
13
-
-
70349148223
-
Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model
-
Lynch HT, Lynch JF, Attard TA. Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model. CMAJ 2009;181:273-80.
-
(2009)
CMAJ
, vol.181
, pp. 273-280
-
-
Lynch, H.T.1
Lynch, J.F.2
Attard, T.A.3
-
15
-
-
0027467494
-
Extracolonic cancer in hereditary nonpolyposis colorectal cancer
-
Watson P, Lynch HT. Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer 1993;71:677-85.
-
(1993)
Cancer
, vol.71
, pp. 677-685
-
-
Watson, P.1
Lynch, H.T.2
-
16
-
-
0031012805
-
Cancer risk associated with germline DNA mismatch repair gene mutations
-
Dunlop MG, Farrington SM, Carothers AD, et al. Cancer risk associated with germline DNA mismatch repair gene mutations. Hum Mol Genet 1997;6:105-10.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 105-110
-
-
Dunlop, M.G.1
Farrington, S.M.2
Carothers, A.D.3
-
17
-
-
0028970197
-
The molecular basis of Turcot's syndrome
-
Hamilton SR, Liu B, Parsons RE, et al. The molecular basis of Turcot's syndrome. N Engl J Med 1995;332:839-47.
-
(1995)
N Engl J Med
, vol.332
, pp. 839-847
-
-
Hamilton, S.R.1
Liu, B.2
Parsons, R.E.3
-
18
-
-
0027515364
-
Muir-Torre syndrome: heterogeneity, natural history, diagnosis, and management
-
Lynch HT, Fusaro RM. Muir-Torre syndrome: heterogeneity, natural history, diagnosis, and management. Prob Gen Surg 1993;10:1-14.
-
(1993)
Prob Gen Surg
, vol.10
, pp. 1-14
-
-
Lynch, H.T.1
Fusaro, R.M.2
-
19
-
-
0029966487
-
Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome
-
Risinger JI, Barrett JC, Watson P, et al. Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome. Cancer 1996;77:1836-43.
-
(1996)
Cancer
, vol.77
, pp. 1836-1843
-
-
Risinger, J.I.1
Barrett, J.C.2
Watson, P.3
-
20
-
-
0032730774
-
Genetic susceptibility to non-polyposis colorectal cancer
-
Lynch HT, de la Chapelle A. Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet 1999;36:801-18.
-
(1999)
J Med Genet
, vol.36
, pp. 801-818
-
-
Lynch, H.T.1
de la Chapelle, A.2
-
21
-
-
0031910118
-
A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype
-
Nicolaides NC, Littman SJ, Modrich P, et al. A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype. Mol Cell Biol 1998;18:1635-41.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1635-1641
-
-
Nicolaides, N.C.1
Littman, S.J.2
Modrich, P.3
-
22
-
-
0001628596
-
Familial endometrial cancer in female carriers of MSH6 germline mutations
-
Wijnen J, de Leeuw W, Vasen H, et al. Familial endometrial cancer in female carriers of MSH6 germline mutations. Nat Genet 1999;23:142-4.
-
(1999)
Nat Genet
, vol.23
, pp. 142-144
-
-
Wijnen, J.1
de Leeuw, W.2
Vasen, H.3
-
23
-
-
0035886698
-
MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families
-
Vasen HF, Stormorken A, Menko FH, et al. MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families. J Clin Oncol 2001;19:4074-80.
-
(2001)
J Clin Oncol
, vol.19
, pp. 4074-4080
-
-
Vasen, H.F.1
Stormorken, A.2
Menko, F.H.3
-
24
-
-
3242670404
-
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
-
Hendriks YM, Wagner A, Morreau H, et al. Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance. Gastroenterology 2004;127:17-25.
-
(2004)
Gastroenterology
, vol.127
, pp. 17-25
-
-
Hendriks, Y.M.1
Wagner, A.2
Morreau, H.3
-
25
-
-
29144462041
-
Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations
-
Bandipalliam P. Syndrome of early onset colon cancers, hematologic malignancies & features of neurofibromatosis in HNPCC families with homozygous mismatch repair gene mutations. Fam Cancer 2005;4:323-33.
-
(2005)
Fam Cancer
, vol.4
, pp. 323-333
-
-
Bandipalliam, P.1
-
26
-
-
23844494113
-
Phenotype associated with recessively inherited mutations in DNA mismatch repair (MMR) genes
-
de Vos M, Hayward B, Bonthron DT, et al. Phenotype associated with recessively inherited mutations in DNA mismatch repair (MMR) genes. Biochem Soc Trans 2005;33:718-20.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 718-720
-
-
de Vos, M.1
Hayward, B.2
Bonthron, D.T.3
-
27
-
-
39049084248
-
Familial T-cell non-Hodgkin lymphoma caused by biallelic MSH2 mutations
-
Scott RH, Homfray T, Huxter NL, et al. Familial T-cell non-Hodgkin lymphoma caused by biallelic MSH2 mutations. J Med Genet 2007;44:e83.
-
(2007)
J Med Genet
, vol.44
, pp. e83
-
-
Scott, R.H.1
Homfray, T.2
Huxter, N.L.3
-
28
-
-
40049112855
-
Non-Hodgkin lymphoma related to hereditary nonpolyposis colorectal cancer in a patient with a novel heterozygous complex deletion in the MSH2 gene
-
Pineda M, Castellsagué E, Musulén E, et al. Non-Hodgkin lymphoma related to hereditary nonpolyposis colorectal cancer in a patient with a novel heterozygous complex deletion in the MSH2 gene. Genes Chromosomes Cancer 2008;47:326-32.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 326-332
-
-
Pineda, M.1
Castellsagué, E.2
Musulén, E.3
-
29
-
-
16544395180
-
A homozygous MSH6 mutation in a child with café-au-lait spots, oligodendroglioma and rectal cancer
-
Menko FH, Kaspers GL, Meijer GA, et al. A homozygous MSH6 mutation in a child with café-au-lait spots, oligodendroglioma and rectal cancer. Fam Cancer 2004;3:123-7.
-
(2004)
Fam Cancer
, vol.3
, pp. 123-127
-
-
Menko, F.H.1
Kaspers, G.L.2
Meijer, G.A.3
-
30
-
-
0033556009
-
Neurofibromatosis and early onset of cancers in hMLH1-deficient children
-
Wang Q, Lasset C, Desseigne F, et al. Neurofibromatosis and early onset of cancers in hMLH1-deficient children. Cancer Res 1999;59:294-7.
-
(1999)
Cancer Res
, vol.59
, pp. 294-297
-
-
Wang, Q.1
Lasset, C.2
Desseigne, F.3
-
31
-
-
0345222475
-
Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1
-
Ricciardone MD, Ozçelik T, Cevher B, et al. Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1. Cancer Res 1999;59:290-3.
-
(1999)
Cancer Res
, vol.59
, pp. 290-293
-
-
Ricciardone, M.D.1
Ozçelik, T.2
Cevher, B.3
-
32
-
-
0001510499
-
Evidence for a recessive inheritance of Turcot's syndrome caused by compound heterozygous mutations within the PMS2 gene
-
De Rosa M, Fasano C, Panariello L, et al. Evidence for a recessive inheritance of Turcot's syndrome caused by compound heterozygous mutations within the PMS2 gene. Oncogene 2000;19:1719-23.
-
(2000)
Oncogene
, vol.19
, pp. 1719-1723
-
-
De Rosa, M.1
Fasano, C.2
Panariello, L.3
-
33
-
-
0035360278
-
Extensive somatic microsatellite mutations in normal human tissue
-
Vilkki S, Tsao JL, Loukola A, et al. Extensive somatic microsatellite mutations in normal human tissue. Cancer Res 2001;61:4541-4.
-
(2001)
Cancer Res
, vol.61
, pp. 4541-4544
-
-
Vilkki, S.1
Tsao, J.L.2
Loukola, A.3
-
34
-
-
0035770411
-
Café-au-lait spots and early onset colorectal neoplasia: a variant of HNPCC?
-
Trimbath JD, Petersen GM, Erdman SH, et al. Café-au-lait spots and early onset colorectal neoplasia: a variant of HNPCC? Fam Cancer 2001;1:101-5.
-
(2001)
Fam Cancer
, vol.1
, pp. 101-105
-
-
Trimbath, J.D.1
Petersen, G.M.2
Erdman, S.H.3
-
35
-
-
0037081077
-
A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple café-au-lait spots
-
Whiteside D, McLeod R, Graham G, et al. A homozygous germ-line mutation in the human MSH2 gene predisposes to hematological malignancy and multiple café-au-lait spots. Cancer Res 2002;62:359-62.
-
(2002)
Cancer Res
, vol.62
, pp. 359-362
-
-
Whiteside, D.1
McLeod, R.2
Graham, G.3
-
36
-
-
0037221952
-
Early onset brain tumor and lymphoma in MSH2-deficient children
-
Bougeard G, Charbonnier F, Moerman A, et al. Early onset brain tumor and lymphoma in MSH2-deficient children. Am J Hum Genet 2003;72:213-6.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 213-216
-
-
Bougeard, G.1
Charbonnier, F.2
Moerman, A.3
-
37
-
-
10744228073
-
Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation
-
Gallinger S, Aronson M, Shayan K, et al. Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation. Gastroenterology 2004;126:576-85.
-
(2004)
Gastroenterology
, vol.126
, pp. 576-585
-
-
Gallinger, S.1
Aronson, M.2
Shayan, K.3
-
38
-
-
3342984883
-
Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome
-
Broaddus RR, Lynch PM, Lu KH, et al. Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome. Mod Pathol 2004;17:981-9.
-
(2004)
Mod Pathol
, vol.17
, pp. 981-989
-
-
Broaddus, R.R.1
Lynch, P.M.2
Lu, K.H.3
-
39
-
-
0034526111
-
Adrenocortical adenocarcinoma in an MSH2 carrier: coincidence or causal relation?
-
Berends MJ, Cats A, Hollema H, et al. Adrenocortical adenocarcinoma in an MSH2 carrier: coincidence or causal relation? Hum Pathol 2000;31:1522-7.
-
(2000)
Hum Pathol
, vol.31
, pp. 1522-1527
-
-
Berends, M.J.1
Cats, A.2
Hollema, H.3
-
40
-
-
0013878809
-
Hereditary factors in cancer. Study of two large midwestern kindreds
-
Lynch HT, Shaw MW, Magnuson CW, et al. Hereditary factors in cancer. Study of two large midwestern kindreds. Arch Intern Med 1966;117:206-12.
-
(1966)
Arch Intern Med
, vol.117
, pp. 206-212
-
-
Lynch, H.T.1
Shaw, M.W.2
Magnuson, C.W.3
-
41
-
-
0033763207
-
Inclusion of malignant fibrous histiocytoma in the tumour spectrum associated with hereditary non-polyposis colorectal cancer
-
Sijmons R, Hofstra R, Hollema H, et al. Inclusion of malignant fibrous histiocytoma in the tumour spectrum associated with hereditary non-polyposis colorectal cancer. Genes Chromosomes Cancer 2000;29:353-5.
-
(2000)
Genes Chromosomes Cancer
, vol.29
, pp. 353-355
-
-
Sijmons, R.1
Hofstra, R.2
Hollema, H.3
-
42
-
-
0032974544
-
Male breast cancer in the hereditary nonpolyposis colorectal cancer syndrome
-
Boyd J, Rhei E, Federici MG, et al. Male breast cancer in the hereditary nonpolyposis colorectal cancer syndrome. Breast Cancer Res Treat 1999;53:87-91.
-
(1999)
Breast Cancer Res Treat
, vol.53
, pp. 87-91
-
-
Boyd, J.1
Rhei, E.2
Federici, M.G.3
-
43
-
-
59749085710
-
Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome
-
Kovacs ME, Papp J, Szentirmay Z, et al. Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome. Hum Mutat 2009;30:197-203.
-
(2009)
Hum Mutat
, vol.30
, pp. 197-203
-
-
Kovacs, M.E.1
Papp, J.2
Szentirmay, Z.3
-
44
-
-
66549109535
-
Silencing is not-so golden: a new model for inheritance of Lynch syndrome
-
Kobelka CE. Silencing is not-so golden: a new model for inheritance of Lynch syndrome. Clin Genet 2009;75:522-3.
-
(2009)
Clin Genet
, vol.75
, pp. 522-523
-
-
Kobelka, C.E.1
-
45
-
-
58149144567
-
Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1
-
Ligtenberg MJ, Kuiper RP, Chan TL, et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. Nat Genet 2009;41:112-7.
-
(2009)
Nat Genet
, vol.41
, pp. 112-117
-
-
Ligtenberg, M.J.1
Kuiper, R.P.2
Chan, T.L.3
-
46
-
-
79952754996
-
Recurrence and variability of germline EPCAM deletions in Lynch syndrome
-
Kuiper RP, Vissers LE, Venkatachalam R, et al. Recurrence and variability of germline EPCAM deletions in Lynch syndrome. Hum Mutat 2011;32:407-14.
-
(2011)
Hum Mutat
, vol.32
, pp. 407-414
-
-
Kuiper, R.P.1
Vissers, L.E.2
Venkatachalam, R.3
-
47
-
-
80053909171
-
Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion
-
Lynch HT, Riegert-Johnson DL, Snyder C, et al. Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion. Am J Gastroenterol 2011;106:1829-36.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 1829-1836
-
-
Lynch, H.T.1
Riegert-Johnson, D.L.2
Snyder, C.3
-
48
-
-
20244386256
-
Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X
-
Lindor NM, Rabe K, Petersen GM, et al. Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. JAMA 2005;293:1979-85.
-
(2005)
JAMA
, vol.293
, pp. 1979-1985
-
-
Lindor, N.M.1
Rabe, K.2
Petersen, G.M.3
-
49
-
-
27144484911
-
Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway
-
Llor X, Pons E, Xicola RM, et al. Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway. Clin Cancer Res 2005;11:7304-10.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7304-7310
-
-
Llor, X.1
Pons, E.2
Xicola, R.M.3
-
50
-
-
33947539706
-
Clinicopathologic and pedigree differences in amsterdam I-positive hereditary nonpolyposis colorectal cancer families according to tumor microsatellite instability status
-
Valle L, Perea J, Carbonell P, et al. Clinicopathologic and pedigree differences in amsterdam I-positive hereditary nonpolyposis colorectal cancer families according to tumor microsatellite instability status. J Clin Oncol 2007;25:781-51.
-
(2007)
J Clin Oncol
, vol.25
, pp. 751-781
-
-
Valle, L.1
Perea, J.2
Carbonell, P.3
-
51
-
-
0032146118
-
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
-
Cunningham JM, Christensen ER, Tester DJ, et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res 1998;58:3455-60.
-
(1998)
Cancer Res
, vol.58
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
-
52
-
-
0032852979
-
Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors
-
Marcus VA, Madlensky L, Gryfe R, et al. Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors. Am J Surg Pathol 1999;23:1248-55.
-
(1999)
Am J Surg Pathol
, vol.23
, pp. 1248-1255
-
-
Marcus, V.A.1
Madlensky, L.2
Gryfe, R.3
-
53
-
-
59849108362
-
Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives
-
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group
-
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group. Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. Genet Med 2009;11:35-41.
-
(2009)
Genet Med
, vol.11
, pp. 35-41
-
-
-
54
-
-
79960604164
-
Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis
-
Ladabaum U, Wang G, Terdiman J, et al. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med 2011;155:69-79.
-
(2011)
Ann Intern Med
, vol.155
, pp. 69-79
-
-
Ladabaum, U.1
Wang, G.2
Terdiman, J.3
-
55
-
-
79960611444
-
Who should have genetic testing for the Lynch syndrome?
-
Burt RW. Who should have genetic testing for the Lynch syndrome? Ann Intern Med 2011;155:127-8.
-
(2011)
Ann Intern Med
, vol.155
, pp. 127-128
-
-
Burt, R.W.1
-
56
-
-
59849108152
-
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group
-
Teutsch SM, Bradley LA, Palomaki GE, et al. The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group. Genet Med 2009;11:3-14.
-
(2009)
Genet Med
, vol.11
, pp. 3-14
-
-
Teutsch, S.M.1
Bradley, L.A.2
Palomaki, G.E.3
-
57
-
-
77149122082
-
The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer
-
Mvundura M, Grosse SD, Hampel H, et al. The cost-effectiveness of genetic testing strategies for Lynch syndrome among newly diagnosed patients with colorectal cancer. Genet Med 2010;12:93-104.
-
(2010)
Genet Med
, vol.12
, pp. 93-104
-
-
Mvundura, M.1
Grosse, S.D.2
Hampel, H.3
-
58
-
-
77955053291
-
Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
-
Vasen HF, Möslein G, Alonso A, et al. Recommendations to improve identification of hereditary and familial colorectal cancer in Europe. Fam Cancer 2010;9:109-15.
-
(2010)
Fam Cancer
, vol.9
, pp. 109-115
-
-
Vasen, H.F.1
Möslein, G.2
Alonso, A.3
-
59
-
-
0034011564
-
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
-
Järvinen HJ, Aarnio M, Mustonen H, et al. Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 2000;118:829-34.
-
(2000)
Gastroenterology
, vol.118
, pp. 829-834
-
-
Järvinen, H.J.1
Aarnio, M.2
Mustonen, H.3
-
60
-
-
27744477699
-
Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study
-
Dove-Edwin I, Sasieni P, Adams J, et al. Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study. BMJ 2005;331:1047.
-
(2005)
BMJ
, vol.331
, pp. 1047
-
-
Dove-Edwin, I.1
Sasieni, P.2
Adams, J.3
-
61
-
-
0026511623
-
Evolution of hereditary non-polyposis colorectal cancer
-
Jass JR, Stewart SM. Evolution of hereditary non-polyposis colorectal cancer. Gut 1992;33:783-6.
-
(1992)
Gut
, vol.33
, pp. 783-786
-
-
Jass, J.R.1
Stewart, S.M.2
-
62
-
-
0029005780
-
Interval cancers in hereditary non-polyposis colorectal cancer (Lynch syndrome)
-
Vasen HF, Nagengast FM, Khan PM. Interval cancers in hereditary non-polyposis colorectal cancer (Lynch syndrome). Lancet 1995;345:1183-4.
-
(1995)
Lancet
, vol.345
, pp. 1183-1184
-
-
Vasen, H.F.1
Nagengast, F.M.2
Khan, P.M.3
-
63
-
-
0032460496
-
Hereditary colon cancers can be tiny: a cautionary case report of the results of colonoscopic surveillance
-
Church J. Hereditary colon cancers can be tiny: a cautionary case report of the results of colonoscopic surveillance. Am J Gastroenterol 1998;93:2289-90.
-
(1998)
Am J Gastroenterol
, vol.93
, pp. 2289-2290
-
-
Church, J.1
-
64
-
-
0031022236
-
Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies
-
Rex DK, Cutler CS, Lemmel GT, et al. Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology 1997;112:24-8.
-
(1997)
Gastroenterology
, vol.112
, pp. 24-28
-
-
Rex, D.K.1
Cutler, C.S.2
Lemmel, G.T.3
-
65
-
-
0030064756
-
Is there a role for prophylactic subtotal colectomy among hereditary nonpolyposis colorectal cancer germline mutation carriers?
-
Lynch HT. Is there a role for prophylactic subtotal colectomy among hereditary nonpolyposis colorectal cancer germline mutation carriers? Dis Colon Rectum 1996;39:109-10.
-
(1996)
Dis Colon Rectum
, vol.39
, pp. 109-110
-
-
Lynch, H.T.1
-
66
-
-
0030451233
-
Prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer
-
Church JM. Prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer. Ann Med 1996;28:479-82.
-
(1996)
Ann Med
, vol.28
, pp. 479-482
-
-
Church, J.M.1
-
67
-
-
0032533172
-
Benefits of colonoscopic surveillance and prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer mutations
-
Syngal S, Weeks JC, Schrag D, et al. Benefits of colonoscopic surveillance and prophylactic colectomy in patients with hereditary nonpolyposis colorectal cancer mutations. Ann Intern Med 1998;129:787-96.
-
(1998)
Ann Intern Med
, vol.129
, pp. 787-796
-
-
Syngal, S.1
Weeks, J.C.2
Schrag, D.3
-
68
-
-
30944457531
-
Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome
-
Schmeler KM, Lynch HT, Chen LM, et al. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N Engl J Med 2006;354:261-9.
-
(2006)
N Engl J Med
, vol.354
, pp. 261-269
-
-
Schmeler, K.M.1
Lynch, H.T.2
Chen, L.M.3
-
69
-
-
0027763498
-
Molecular diagnosis of familial adenomatous polyposis
-
Powell SM, Petersen GM, Krush AJ, et al. Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 1993;329:1982-7.
-
(1993)
N Engl J Med
, vol.329
, pp. 1982-1987
-
-
Powell, S.M.1
Petersen, G.M.2
Krush, A.J.3
-
70
-
-
0023223410
-
Localization of the gene for familial adenomatous polyposis on chromosome 5
-
Bodmer WF, Bailey CJ, Bodmer J, et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987;328:614-6.
-
(1987)
Nature
, vol.328
, pp. 614-616
-
-
Bodmer, W.F.1
Bailey, C.J.2
Bodmer, J.3
-
71
-
-
0023572211
-
The gene for familial polyposis coli maps to the long arm of chromosome 5
-
Leppert M, Dobbs M, Scambler P, et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 1987;238:1411-3.
-
(1987)
Science
, vol.238
, pp. 1411-1413
-
-
Leppert, M.1
Dobbs, M.2
Scambler, P.3
-
72
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK, et al. Identification of FAP locus genes from chromosome 5q21. Science 1991;253:661-5.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
-
73
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Y, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 1991;253:665-9.
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
-
74
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992;359:235-7.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
-
75
-
-
0031837883
-
Upper gastrointestinal disease in patients with familial adenomatous polyposis
-
Wallace MH, Phillips RK. Upper gastrointestinal disease in patients with familial adenomatous polyposis. Br J Surg 1998;85:742-50.
-
(1998)
Br J Surg
, vol.85
, pp. 742-750
-
-
Wallace, M.H.1
Phillips, R.K.2
-
76
-
-
0026664339
-
Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus
-
Spirio L, Otterud B, Stauffer D, et al. Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus. Am J Hum Genet 1992;51:92-100.
-
(1992)
Am J Hum Genet
, vol.51
, pp. 92-100
-
-
Spirio, L.1
Otterud, B.2
Stauffer, D.3
-
77
-
-
0027724691
-
Alleles of the APC gene: an attenuated form of familial polyposis
-
Spirio L, Olschwang S, Groden J, et al. Alleles of the APC gene: an attenuated form of familial polyposis. Cell 1993;75:951-7.
-
(1993)
Cell
, vol.75
, pp. 951-957
-
-
Spirio, L.1
Olschwang, S.2
Groden, J.3
-
78
-
-
0028823186
-
Attenuated familial adenomatous polyposis (AFAP). A phenotypically and genotypically distinctive variant of FAP
-
Lynch HT, Smyrk T, McGinn T, et al. Attenuated familial adenomatous polyposis (AFAP). A phenotypically and genotypically distinctive variant of FAP. Cancer 1995;76:2427-33.
-
(1995)
Cancer
, vol.76
, pp. 2427-2433
-
-
Lynch, H.T.1
Smyrk, T.2
McGinn, T.3
-
79
-
-
0033569812
-
Chemoprevention in hereditary colorectal cancer syndromes
-
Hawk E, Lubet R, Limburg P. Chemoprevention in hereditary colorectal cancer syndromes. Cancer 1999;86:2551-63.
-
(1999)
Cancer
, vol.86
, pp. 2551-2563
-
-
Hawk, E.1
Lubet, R.2
Limburg, P.3
-
80
-
-
0028323658
-
Use of doxorubicin and dacarbazine for the management of unresectable intra-abdominal desmoid tumors in Gardner,s syndrome
-
Lynch HT, Fitzgibbons R Jr, Chong S, et al. Use of doxorubicin and dacarbazine for the management of unresectable intra-abdominal desmoid tumors in Gardner,s syndrome. Dis Colon Rectum 1994;37:260-7.
-
(1994)
Dis Colon Rectum
, vol.37
, pp. 260-267
-
-
Lynch, H.T.1
Fitzgibbons, R.2
Chong, S.3
-
81
-
-
0029902433
-
Surgery, desmoid tumors, and familial adenomatous polyposis: case report and literature review
-
Lynch HT, Fitzgibbons R Jr. Surgery, desmoid tumors, and familial adenomatous polyposis: case report and literature review. Am J Gastroenterol 1996;91:2598-601.
-
(1996)
Am J Gastroenterol
, vol.91
, pp. 2598-2601
-
-
Lynch, H.T.1
Fitzgibbons, R.2
-
82
-
-
0027953855
-
Desmoid tumors in patients with familial adenomatous polyposis
-
Rodriguez-Bigas MA, Mahoney MC, Karakousis CP, et al. Desmoid tumors in patients with familial adenomatous polyposis. Cancer 1994;74:1270-4.
-
(1994)
Cancer
, vol.74
, pp. 1270-1274
-
-
Rodriguez-Bigas, M.A.1
Mahoney, M.C.2
Karakousis, C.P.3
-
83
-
-
0029811242
-
Desmoid tumors: genotype-phenotype differences in familial adenomatous polyposis--a nosological dilemma
-
Lynch HT. Desmoid tumors: genotype-phenotype differences in familial adenomatous polyposis--a nosological dilemma. Am J Hum Genet 1996;59:1184-5.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 1184-1185
-
-
Lynch, H.T.1
-
84
-
-
0034768413
-
Familial adenomatous polyposis and extracolonic cancer
-
Lynch HT, Thorson AG, McComb RD, et al. Familial adenomatous polyposis and extracolonic cancer. Dig Dis Sci 2001;46:2325-32.
-
(2001)
Dig Dis Sci
, vol.46
, pp. 2325-2332
-
-
Lynch, H.T.1
Thorson, A.G.2
McComb, R.D.3
-
85
-
-
0037468517
-
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
-
Sieber OM, Lipton L, Crabtree M, et al. Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med 2003;348:791-9.
-
(2003)
N Engl J Med
, vol.348
, pp. 791-799
-
-
Sieber, O.M.1
Lipton, L.2
Crabtree, M.3
-
86
-
-
34547920290
-
Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations
-
Nielsen M, Hes FJ, Vasen HF, et al. Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations. BMC Med Genet 2007;8:42.
-
(2007)
BMC Med Genet
, vol.8
, pp. 42
-
-
Nielsen, M.1
Hes, F.J.2
Vasen, H.F.3
-
87
-
-
3342939012
-
Adenomas of the large intestine in children
-
Helwig EB. Adenomas of the large intestine in children. Am J Dis Child 1946;72:289-95.
-
(1946)
Am J Dis Child
, vol.72
, pp. 289-295
-
-
Helwig, E.B.1
-
89
-
-
0027268069
-
Solitary juvenile polyps: not a marker for subsequent malignancy
-
Nugent KP, Talbot IC, Hodgson SV, et al. Solitary juvenile polyps: not a marker for subsequent malignancy. Gastroenterology 1993;105:698-700.
-
(1993)
Gastroenterology
, vol.105
, pp. 698-700
-
-
Nugent, K.P.1
Talbot, I.C.2
Hodgson, S.V.3
-
90
-
-
0031971514
-
Molecular classification of the inherited hamartoma polyposis syndromes: clearing the muddied waters
-
Eng C, Ji H. Molecular classification of the inherited hamartoma polyposis syndromes: clearing the muddied waters. Am J Hum Genet 1998;62:1020-2.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1020-1022
-
-
Eng, C.1
Ji, H.2
-
92
-
-
0028891955
-
Familial juvenile polyposis: patterns of recurrence and implications for surgical management
-
Scott-Conner CE, Hausmann M, Hall TJ, et al. Familial juvenile polyposis: patterns of recurrence and implications for surgical management. J Am Coll Surg 1995;181:407-13.
-
(1995)
J Am Coll Surg
, vol.181
, pp. 407-413
-
-
Scott-Conner, C.E.1
Hausmann, M.2
Hall, T.J.3
-
93
-
-
0027484239
-
Juvenile gastrointestinal polyposis
-
Järvinen HJ. Juvenile gastrointestinal polyposis. Prob Clin Surg 1993;10:749-57.
-
(1993)
Prob Clin Surg
, vol.10
, pp. 749-757
-
-
Järvinen, H.J.1
-
94
-
-
0031673225
-
The risk of gastrointestinal carcinoma in familial juvenile polyposis
-
Howe JR, Mitros FA, Summers RW. The risk of gastrointestinal carcinoma in familial juvenile polyposis. Ann Surg Oncol 1998;5:751-6.
-
(1998)
Ann Surg Oncol
, vol.5
, pp. 751-756
-
-
Howe, J.R.1
Mitros, F.A.2
Summers, R.W.3
-
95
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
Jenne DE, Reimann H, Nezu J, et al. Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 1998;18:38-43.
-
(1998)
Nat Genet
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
-
96
-
-
0031012344
-
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
Hemminki A, Tomlinson I, Markie D, et al. Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 1997;15:87-90.
-
(1997)
Nat Genet
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
-
97
-
-
17344367301
-
Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3
-
Olschwang S, Markie D, Seal S, et al. Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3. J Med Genet 1998;35:42-4.
-
(1998)
J Med Genet
, vol.35
, pp. 42-44
-
-
Olschwang, S.1
Markie, D.2
Seal, S.3
-
98
-
-
17344365130
-
Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4
-
Mehenni H, Blouin JL, Radhakrishna U, et al. Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4. Am J Hum Genet 1997;61:1327-34.
-
(1997)
Am J Hum Genet
, vol.61
, pp. 1327-1334
-
-
Mehenni, H.1
Blouin, J.L.2
Radhakrishna, U.3
-
99
-
-
13944265646
-
The hamartomatous polyposis syndromes: a clinical and molecular review
-
Schreibman IR, Baker M, Amos C, et al. The hamartomatous polyposis syndromes: a clinical and molecular review. Am J Gastroenterol 2005;100:476-90.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 476-490
-
-
Schreibman, I.R.1
Baker, M.2
Amos, C.3
-
100
-
-
0023192463
-
Increased risk of cancer in the Peutz-Jeghers syndrome
-
Giardiello FM, Welsh SB, Hamilton SR, et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 1987;316:1511-4.
-
(1987)
N Engl J Med
, vol.316
, pp. 1511-1514
-
-
Giardiello, F.M.1
Welsh, S.B.2
Hamilton, S.R.3
-
101
-
-
0033541557
-
Peutz-Jeghers syndrome: 78-year follow-up of the original family
-
Westerman AM, Entius MM, de Baar E, et al. Peutz-Jeghers syndrome: 78-year follow-up of the original family. Lancet 1999;353:1211-5.
-
(1999)
Lancet
, vol.353
, pp. 1211-1215
-
-
Westerman, A.M.1
Entius, M.M.2
de Baar, E.3
-
102
-
-
0024350881
-
Cancer and the Peutz-Jeghers syndrome
-
Spigelman AD, Murday V, Phillips RK. Cancer and the Peutz-Jeghers syndrome. Gut 1989;30:1588-90.
-
(1989)
Gut
, vol.30
, pp. 1588-1590
-
-
Spigelman, A.D.1
Murday, V.2
Phillips, R.K.3
-
103
-
-
15444350943
-
Increased risk for cancer in patients with the Peutz-Jeghers syndrome
-
Boardman LA, Thibodeau SN, Schaid DJ, et al. Increased risk for cancer in patients with the Peutz-Jeghers syndrome. Ann Intern Med 1998;128:896-9.
-
(1998)
Ann Intern Med
, vol.128
, pp. 896-899
-
-
Boardman, L.A.1
Thibodeau, S.N.2
Schaid, D.J.3
-
104
-
-
0019963714
-
Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix
-
Young RH, Welch WR, Dickersin GR, et al. Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. Cancer 1982;50:1384-402.
-
(1982)
Cancer
, vol.50
, pp. 1384-1402
-
-
Young, R.H.1
Welch, W.R.2
Dickersin, G.R.3
-
107
-
-
0042327828
-
Carrier risk status changes resulting from mutation testing in hereditary non-polyposis colorectal cancer and hereditary breast-ovarian cancer
-
Watson P, Narod SA, Fodde R, et al. Carrier risk status changes resulting from mutation testing in hereditary non-polyposis colorectal cancer and hereditary breast-ovarian cancer. J Med Genet 2003;40:591-6.
-
(2003)
J Med Genet
, vol.40
, pp. 591-596
-
-
Watson, P.1
Narod, S.A.2
Fodde, R.3
|