pap, reg Iα and reg Iβ mRNAs are concomitantly up-regulated during human colorectal carcinogenesis

International Journal of Cancer

Volumn 81, Issue 5, 1999, Pages 688-694

  Rechreche, Hocine ^a   Montalto, Guiseppe ^b   Mallo, Gustavo V ^a   Vasseur, Sophie ^a   Marasa, Lorenzo ^c   Soubeyran, Philippe ^a   Dagorn, Jean Charles ^a   Iovanna, Juan L ^a  

^a INSERM   (France)

^b UNIVERSITY OF PALERMO   (Italy)

^c Ospedale Oncologico M Ascoli   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 6; MESSENGER RNA; ONCOPROTEIN; SECRETORY PROTEIN; CALCIUM BINDING PROTEIN; CELL SURFACE RECEPTOR; EPITHELIAL MEMBRANE PROTEIN 1; EPITHELIAL MEMBRANE PROTEIN-1; LITHOSTATHINE; NERVE PROTEIN; REG1A PROTEIN, HUMAN; TUMOR MARKER; TUMOR PROTEIN;

ADENOCARCINOMA; ARTICLE; CARCINOGENESIS; CARCINOMA CELL; CLINICAL ARTICLE; COLON MUCOSA; COLORECTAL CARCINOMA; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MEDIATOR; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; CELL CULTURE; CELL STRAIN HT29; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NORTHERN BLOTTING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

BLOTTING, NORTHERN; CALCIUM-BINDING PROTEINS; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LITHOSTATHINE; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 0032588360     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990531)81:5<688::AID-IJC3>3.0.CO;2-R     Document Type: Article

References (42)

1. BARTOLI, C., DAGORN, J.C., FONTES, M. and BERGE-LEFRANC, J.L., A limited genomic region contains the human REG and REG-related genes. Europ. J. Hum. Genet., 3, 344-350 (1995).
2. BARTOLI, C., GHARIB, B., GIORGI, D., SANSONETTI, A., DAGORN, J.C. and BERGE-LEFRANC, J.L., A gene homologous to the reg gene is expressed in the human pancreas. FEBS Lett., 327, 289-293 (1993).
3. BRADFORD, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254 (1976).
4. CHANTRET, I., BARBAT, A., DUSSAULX, E., BRATTAIN, M.G. and ZWEIBAUM, A., Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines. Cancer Res., 48, 1936-1942 (1988).
5. CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
6. CHRISTA, L., CARNOT, F., SIMON, M.T., LEVAVASSEUR, F., STINNAKRE, M.G., LASSERRE, C., THEPOT, D., CLEMENT, B., DEVINOY, E. and BRECHOT, C., hip/pap is an adhesive protein expressed in hepatocarcinoma, normal Paneth and pancreatic cells. Amer. J. Physiol., 271, G993-G1002 (1996).
7. DE CARO, A., MULTIGNER, L., LAFONT, H., LOMBARDO, D. and SARLES, H., The molecular characteristics of a human pancreatic acidic phosphoprotein that inhibits calcium carbonate-crystal growth. Biochem. J., 222, 669-677 (1984).
8. DUSETTI, N.J., FRIGERIO, J.M., FOX, M.F., SWALLOW, D.M., DAGORN, J.C. and IOVANNA, J.L., Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene. Genomics, 19, 108-114 (1994).
9. DUSETTI, N.J., FRIGERIO, J.M., KEIM, V., DAGORN, J.C. and IOVANNA, J.L., Structural organization of the gene encoding the rat pancreatitis-associated protein. Analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition-domain-containing genes. J. biol. Chem., 268, 14470-14475 (1993).
10. DUSETTI, N.J., MONTALTO, G., ORTIZ, E.M., MASCIOTRA, L., DAGORN, J.C. and IOVANNA, J.L., Mechanism of PAP I gene induction during hepatocarcinogenesis: clinical implications. Brit. J. Cancer, 74, 1767-1775 (1996).
11. DUSETTI, N.J., VASSEUR, S., ORTIZ, E.M., ROMEO, H., DAGORN, J.C., BURRONE, O. and IOVANNA, J.L., The pancreatitis-associated-protein-I promoter allows targeting to the pancreas of a foreign gene, whose expression is up-regulated during pancreatic inflammation. J. biol. Chem., 272, 5800-5804 (1997).
12. FEARON, E.R. and VOGELSTEIN, B., A genetic model for colorectal tumorigenesis. Cell, 61, 759-767 (1990).
13. FRIGERIO, J.M., BERTHEZENE, P., GARRIDO, P., ORTIZ, E., BERTHELLEMY, S., VASSEUR, S., SASTRE, B., SELEZNIEFF, I., DAGORN, J.C. and IOVANNA, J.L., Analysis of 2166 clones from a human colorectal-cancer-cDNA library by partial sequencing. Hum. mol. Genet., 4, 37-43 (1995).
14. GIORGI, D., BERNARD, J.P., ROUQUIER, S., IOVANNA, J.L., SARLES, H. and DAGORN, J.C., Secretory pancreatic stone protein messenger RNA. Nucleotide sequence and expression in chronic calcifying pancreatitis. J. clin. Invest., 84, 100-106 (1989).
15. GRANJEAUD, S., NGUYEN, C., ROCHA, D., LUTON, R. and JORDAN, B.R., From hybridization image to numerical values: a practical, high throughput quantification system for high-density filter hybridizations. Genet. Anal., 12, 151-162 (1996).
16. IOVANNA, J.L., KEIM, V., BOSSHARD, A., ORELLE, B., FRIGERIO, J.M., DUSETTI, N.J. and DAGORN, J.C., PAP, a pancreatic secrotory protein induced during acute pancreatitis, is expressed in rat intestine. Amer. J. Physiol., 265, G611-G618 (1993).
17. IOVANNA, J.L., KEIM, V., MICHEL, R. and DAGORN, J.C., Pancreatic gene expression is altered during acute experimental pancreatitis in the rat. Amer. J. Physiol., 261, G485-G489 (1991).
18. IHTO, T., and TERAOKA, H., Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). Biochim. biophys. Acta, 1172, 184-186 (1993).
19. KATSUMATA, N., CHAKRABORTY, C., MYAL, Y., SCHROEDTER, I.C., MURPHY, L.J., SHIU, R.P. and FRIESEN, H.G., Molecular cloning and expression of peptide 23, a growth hormone-releasing hormone-inducible pituitary protein. Endocrinology, 136, 775-782 (1995).
20. KEIM, V., IOVANNA, J.L., ORELLE, B., VERDIER, J.M., BUSING, M., HOPT, U. and DAGORN, J.C., A novel exocrine protein associated with pancreas transplantation in humans. Gastroenterology, 103, 248-254 (1992).
21. KIMURA, N., YONEKURA, H., OKAMOTO, H. and NAGURA, H., Expression of human regenerating gene mRNA and its product in normal and neoplastic human pancreas. Cancer, 70, 1857-1863 (1992).
22. LASSERRE, C., CHRISTA, L., SIMON, M., VERNIER, P. and BRECHOT, C., A novel gene (HIP) activated in human primary liver cancer. Cancer Res., 52, 5089-5095 (1992).
23. LECHENE DE LA PORTE, P., DE CARO, A., LAFONT, H. and SARLES, H., Immunocytochemical localization of pancreatic stone protein in the human digestive tract. Pancreas, 1, 301-308 (1986).
24. LIVESEY, F.J., O'BRIEN, J.A., LI, M., SMITH, A.G., MURPHY, L.J. and HUNT, S.P., A Schwann cell mitogen accompanying regeneration of motor neurons. Nature (Lond.), 390, 614-618 (1997).
25. MALLO, G.V., RECHRECHE, H., FRIGERIO, J.M., ROCHA, D., ZWEIBAUM, A., LACASA, M., JORDAN, B.R., DUSETTI, N.J., DAGORN, J.C. and IOVANNA, J.L., Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int. J. Cancer, 74, 35-44 (1997).
26. MASCIOTRA, L., LECHENE DE LA PORTE, P., FRIGERIO, J.M., DUSETTI, N.J., DAGORN, J.C. and IOVANNA, J.L., Immunocytochemical localization of the pancreatitis associated protein in the human small intestine. Dig. Dis. Sci., 40, 519-524 (1995).
27. MIYASHITA, H., NAKAGAWARA, K., MORI, M., NARUSHIMA, Y., NOGUCHI, N., MORIIZUMI, S., TAKASAWA, S., YONEKURA, H., TAKEUCHI, T. and OKOMOTO, H., Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12. FEBS Lett., 377, 429-433 (1995).
28. ORELLE, B., KEIM, V., MASCIOTRA, L., DAGORN, J.C. and IOVANNA, J.L., Human pancreatitis associated protein. Messenger RNA cloning and expression in pancreatic diseases. J. clin. Invest., 90, 2284-2291 (1992).
29. ORTIZ, E., DUSETTI, N.J., VASSEUR, S., MALKA, D., BÖDEKER, H., DAGORN, J.C. and IOVANNA, J.L., The pancreatitis associated protein is induced by free radicals in pancreatic AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology, 114, 808-816 (1998).
30. RAFAELOFF, R., PITTENGER, G.L., BARLOW, S.W., QIN, X.F., YAN, B., ROSENBERG, L., DUGUID, W.P. and VINIK, A.I., Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters. J. clin. Invest., 99, 2100-2109 (1997).
31. RECHRECHE, H., MALLO, G.V., MONTALTO, G., DAGORN, J.C. and IOVANNA, J.L., Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer. Europ. J. Biochem., 248, 225-230 (1997).
32. RUSTGI, A.K. and PODOLSKY, D.K., The molecular basis of colon cancer. Ann. Rev. Med., 43, 61-68 (1992).
33. SAMBROOK, J., FRISCH, E.F. and MANIATIS, T., Molecular cloning: a laboratory manual, 2nd ed., Cold Spring Harbor Laboratory Press, New York (1989).
34. SEED, B. and SHEEN, J. Y., A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene, 67, 271-277 (1988).
35. STERNBERGER, L.A., Immunocytochemistry, 2nd ed., pp. 104-69, Wiley, New York, (1979).
36. TERAZONO, K., UCHIYAMA, Y., IDE, M., WATANABE, T., YONEKURA, H., YAMAMOTO, H. and OKAMOTO, H., Expression of reg gene in rat regenerating islets and its co-localization with insulin in the beta-cell secretory granules. Diabetologia, 33, 250-252 (1990).
37. TERAZONO, K., YAMAMOTO, H., TAKASAWA, S., SHIGA, K., YONEMURA, Y., TOCHINO, Y. and OKAMOTO, H., A novel gene activated in regenerating islets. J. biol. Chem., 263, 2111-2114 (1988).
38. WATANABE, T., YONEKURA, H., TERAZONO, K., YAMAMOTO, H. and OKAMOTO, H., Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein and pancreatic thread protein are one and the same product of the gene. J. biol. Chem., 265, 7432-7439 (1990).
39. WATANABE, T. and 12 OTHERS, Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein. Proc. nat. Acad. Sci. (Wash.), 91, 3589-3592 (1994).
40. ZENILMAN, M.E., KIM, S., LEVINE, B.A., LEE, C. and STEINBERG, J.J., Ectopic expression of reg protein: a marker of colorectal mucosa at risk for neoplasia. J. Gastroenterol. Surg., 1, 194-202 (1997).
41. ZENILMAN, M.E., MAGNUSON, T.H., SWINSON, K., EGAN, J., PERFETTI, R. and SHULDINER, A.R., Pancreatic thread protein is mitogenic to pancreatic-derived cells in culture. Gastroenterology, 110, 1208-1214 (1996).
42. ZHANG, L., ZHOU, W., VELCULESCU, V.E., KERN, S.E., HRUBAN, R.H., HAMILTON, S.R., VOGELSTEIN, B. and KINZLER, K.W., Gene expression profiles in normal and cancer cells. Science, 276, 1268-1272 (1997).