Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome

Familial Cancer

Volumn 14, Issue 3, 2015, Pages 415-425

  Cruz Correa, Marcia ^a,b   Diaz Algorri, Yaritza ^a   Pérez Mayoral, Julyann ^a,b   Suleiman Suleiman, Wasilah ^b   del Mar Gonzalez Pons, Maria ^a   Bertrán, Carlos ^a   Casellas, Nicolás ^a   Rodríguez, Natalia ^a   Pardo, Sherly ^b   Rivera, Keyla ^b   Mosquera, Rafael ^c   Rodriguez Quilichini, Segundo ^b  

^a UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

^c Department of Biochemistry University of Puerto Rico School of Medicine ^*  (United States)

Author keywords

Hispanics; Lynch syndrome; Mismatch repair system; MLH1; MSH2; MSH6 and or PMS2

Indexed keywords

MISMATCH REPAIR PROTEIN; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; DNA BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; AGED; ARTICLE; ASCENDING COLON; CANCER REGISTRY; CARIBBEAN (PERSON); DOMINICAN REPUBLIC; FAMILY HISTORY; FEMALE; FOLLOW UP; GENE SEQUENCE; GENETIC COUNSELING; GENETIC RISK; GENETIC SCREENING; GERMLINE MUTATION; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HISPANIC; HUMAN; IMMUNOHISTOCHEMISTRY; INSURANCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; NORMAL HUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PUERTO RICO; SELF REPORT; TUMOR LOCALIZATION; CARIBBEAN; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; ECONOMICS; GENETICS; METABOLISM; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MUIR TORRE SYNDROME; MUTATION; PROCEDURES; REIMBURSEMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; CARIBBEAN REGION; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; FEMALE; GENETIC TESTING; GERM-LINE MUTATION; HISPANIC AMERICANS; HUMANS; INSURANCE, HEALTH, REIMBURSEMENT; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUIR-TORRE SYNDROME; MUTATION; MUTL PROTEIN HOMOLOG 1; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; PUERTO RICO;

EID: 84941022692     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-015-9795-y     Document Type: Article

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